Citations

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4694 total record number 67 records this year

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4694 citations found

A novel regulatory pathway for autoimmune disease: binding of partial MHC class II constructs to monocytes reduces CD74 expression and induces both specific and bystander T-cell tolerance

Vandenbark, AA;Meza-Romero, R;Benedek, G;Andrew, S;Huan, J;Chou, YK;Buenafe, AC;Dahan, R;Reiter, Y;Mooney, JL;Offner, H;Burrows, GG;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Therapeutic effect of cytotoxic T lymphocyte antigen 4/immunoglobulin on a murine model of primary biliary cirrhosis

Dhirapong, A;Yang, GX;Nadler, S;Zhang, W;Tsuneyama, K;Leung, P;Knechtle, S;Ansari, AA;Coppel, RL;Liu, FT;He, XS;Gershwin, ME;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

An obligate cell-intrinsic function for CD28 in Tregs

Zhang, R;Huynh, A;Whitcher, G;Chang, J;Maltzman, JS;Turka, LA;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Specialized role of migratory dendritic cells in peripheral tolerance induction

Idoyaga, J;Fiorese, C;Zbytnuik, L;Lubkin, A;Miller, J;Malissen, B;Mucida, D;Merad, M;Steinman, RM;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Genetic and pharmacological targeting of CSF-1/CSF-1R inhibits tumor-associated macrophages and impairs BRAF-induced thyroid cancer progression

Ryder, M;Gild, M;Hohl, TM;Pamer, E;Knauf, J;Ghossein, R;Joyce, JA;Fagin, JA;

Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae

  • Depletion of TAMs in Braf-induced thyroid cancer mouse models:

    Macrophage depletion in the bone marrow (BM), blood, spleen and peritoneal cavity was examined in Ccr2-DTR mice after treatment with diphtheria toxin (DT) 20 ng/g (List Biologicals, Campbell, CA ) intraperitoneally (i.p.) on alternating days for 7 days. Twenty-four hours following the last dose of DT, mice were euthanized by CO2 inhalation and tissue samples obtained for flow cytometry and/or immunohistochemistry (IHC) as described below.

    To assess the effects of TAMs on PTC development, Tg-rtTA/tetO-Braf/Ccr2-DTR mice were fed dox-impregnated chow (2500 ppm; Harlan-Teklad) for 7 days with or without DT i.p. on alternating days beginning on day 0. On day 7 (24 hr after the last dose of DT), mice were euthanized by CO2 inhalation and thyroids extracted for IHC. To examine the role of TAMs in established BRAF-induced thyroid cancers we treated Tg-Braf/Ccr2-DTR mice at approximately 6 and 12 weeks of age with or without DT on alternating days for 10 days. Mice were euthanized and thyroids extracted 24 hr after the last dose of DT for flow cytometry and IHC.

NVC-422 inactivates Staphylococcus aureus toxins

Jekle, A;Yoon, J;Zuck, M;Najafi, R;Wang, L;Shiau, T;Francavilla, C;Rani, SA;Eitzinger, C;Nagl, M;Anderson, M;Debabov, D;

Product: Enterotoxin Type B from Staphylococcus aureus

  • Materials:

    Staphylococcal enterotoxin B (SEB) was purchased at List Biological Laboratories (Campbell, CA),…

    LC-MS:

    … To avoid undesirable oxidation of cysteines by air oxygenation, digested SEB samples were further treated with 10 mM TCEP [tris(2-carboxyethyl)phosphine] and then with 100 mM iodoacetamide…

2 Adrenergic receptor-mediated inhibition of thermogenesis

Madden, CJ;Tupone, D;Cano, G;Morrison, SF;

Product: Anti-Cholera Toxin B Subunit (Goat)

Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae

Pocketed microneedles for rapid delivery of a liquid-state botulinum toxin A formulation into human skin

Torrisi, BM;Zarnitsyn, V;Prausnitz, MR;Anstey, A;Gateley, C;Birchall, JC;Coulman, SA;

Product: Botulinum Neurotoxin Type A Toxoid from Clostridium botulinum

  • Materials:

    Botulinum neurotoxin type A toxoid and anti botulinum toxin type A chicken IgY were purchased from List Biological Laboratories (Campbell, California, USA).

    Cutaneous delivery of botulinum toxoid A using liquid-loaded PMNs:

    PMNs (n=3) were liquid-loaded, as previously described, with a solution containing formaldehyde inactivated BT i.e. botulinum toxoid (BTD) (100ng/l)…Next, slides were washed with PBS and incubated for 1 h with a diluted primary polyclonal antibody (Anti-botulinum toxin/toxoid type A chichen IgY).

    Cutaneous delivery of fluorescence-conjugated BTD using liquid-loaded PMNs:

    BTD was fluorescently labelled with PE/Cy7 using the EasyLink PE/Cy7 kit…The PMN was then re-imaged by fluorescence and light microscopy to evaluate release of the fluorescent BTD formulation from the pockets.

Simultaneous vaccination and treatment against anthrax

Aulinger, B;

Product: Anthrax Lethal Factor (LF), Recombinant from B. anthracis