Citations

Bacterial Toxin Research Citations

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4945 citations found

Central amygdala-to-pre-Bötzinger complex neurotransmission is direct and inhibitory

Gu, J;Sugimura, YK;Kato, F;Del Negro, CA;

Product: Anti-Cholera Toxin B Subunit (Goat)

  • 2.7 Immunohistochemistry

    … A series of 30 μm-thick transverse sections containing the CeA or the preBötC was prepared with a cryostat (CM1860, Leica Biosystems, Tokyo, Japan). Sections containing the CeA were stored in 0.1 M PBS containing 0.1% sodium azide (Nacalai Tesque, Kyoto, Japan) until immunostaining. We amplified CTb-Alexa-488 via immunostaining (Arima et al., 2019). Sections were washed in 0.1 M PBS, incubated in blocking buffer (PBS containing 0.3% Triton X-100 and 3% normal donkey serum) for 1 h and then incubated overnight with a goat CTb antibody (1:10000, #703, List Labs, Campbell, CA, USA) and a rabbit monoclonal protein kinase C-delta (PKCδ) antibody (1:1000, ab182126, Abcam, Waltham, MA, USA) in blocking buffer. …

    Product #703 – Anti-Cholera Toxin B Subunit (Goat)

Strength training attenuates neuropathic pain by Preventing dendritic Spine dysgenesis through Suppressing Rac1 and inflammation in experimental autoimmune encephalomyelitis

Saffar Kohneh Quchan, AH;Kordi, MR;Mohammadi, G;Amiri Raeez, R;Choobineh, S;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

An analysis of single-cell data reveals therapeutic effects of AMG487 in experimental autoimmune uveitis

Jiang, L;Duan, R;Yu, X;Huang, Z;Peng, X;Wang, T;Li, Z;Liu, X;Wang, M;Su, W;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

  • immunization of mice, the prepared emulsion was mixed with equal volumes of interphotoreceptor retinoid-binding protein (1-20) (IRBP1-20; 2 mg/mL; GPTHLFQPSLVLDMAKVLLD, GiL Biochem, Shanghai, China) phosphate buffer saline (PBS) solution. Injections of pertussis toxin (List Biological Laboratories, Campbell, CA, USA) were administered intraperitoneally on day 0 and day 2. Fundus photograph was taken on day 14 for assessment of clinical scores, and mice were euthanized for histopathology analysis of their eyeballs. Based on previously published evaluation criteria [27], clinical and histological scores were calculated

Nuclear Focal Adhesion Kinase Protects Against Cisplatin Stress in Ovarian Carcinoma

Zhang, Y;Ojalill, M;Boyer, A;Chen, XL;Tahon, E;Thivolle Lioux, G;Xia, M;Abbas, M;Soylu, HM;Flieder, DB;Connolly, DC;Molinolo, AA;McHale, MT;Stupack, DG;Schlaepfer, DD;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

  • D Systems S12450), 0.4 ug/ml hydrocortisone (Stem Cell Technologies 07904), 5 µg/ml insulin (Gibco 12585014), 8.4 ng/ml cholera toxin (List Biological Laboratories Inc. 100B), 10 ng/ml EGF (Gibco PHG0313), 24 ug/ml adenine (Alfa Aesar A14906), 10 µM ROCK inhibitor

Dendritic cells accelerate CAR T cells in irradiated tumors through chimeric synapses

Navarre, S;Ishibashi, M;Nair, A;Reyes-Torres, I;Belabed, M;Halasz, L;Park, M;Mattiuz, R;Ounadjela, M;Gunset, G;Mansilla-Soto, J;Feucht, J;Cabriolu, A;Berichel, J;Eyquem, J;Brown, B;Merad, M;Sadelain, M;Ahmed, J;

Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae

  • Unnicked DT from Corynebacterium diphtheriae was purchased from List Biological 683 Laboratories. Zbtb46-DTR bone marrow chimeras were injected i.p. with a first dose of 640 ng 684 DT per mouse, fol

A novel mouse model of myositis-associated interstitial lung disease was established by using TLR9 agonist combined with muscle homogenate

Bai, L;Zhu, J;Ma, W;Zhao, P;Li, F;Zhang, C;Zhang, S;

Product: Pertussis Toxin from B. pertussis, Lyophilized (Salt-Free)

  • ?g). The MAILD group additionally included two concentration groups of 5?g and 20?g to study the optimal modeling dose of ODN2395. Immunization was carried out at days 0, 7, 14, 21 and 28. Additionally, PTX (List Labs, cat. #: 181, Campbell, California, USA) was intraperi

MRGPRX2 facilitates IgE-mediated systemic anaphylaxis in a newly established knock-in mouse model

Bawazir, M;Sutradhar, S;Roy, S;Ali, H;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

  • dies were obtained from BioLegend (San Diego, CA, USA). FITC132 conjugated anti-mouse Fc?RI antibody (Clone MAR-1, Catalog 11-5898-85) was obtained from eBioscienceTM 133 (San Diego, CA, USA). Pertussis toxin (PTx) was obtained from List Biological 134 Laboratories (Campbell, CA, USA)

Pseudokinase STK40 promotes TH1 and TH17 cell differentiation by targeting FOXO transcription factors

Tao, Y;Jiang, Z;Wang, H;Li, J;Li, X;Ni, J;Liu, J;Xiang, H;Guan, C;Cao, W;Li, D;He, K;Wang, L;Hu, J;Jin, Y;Liao, B;Zhang, T;Wu, X;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

  • (Shanghai) Ltd.] in Freund’s complete adjuvant containing heat-killed Mycobacterium tuberculosis H37Ra (5 mg/ml; BD Difco). On the day of immunization and 48 hours later, 200 ng of pertussis toxin (List Biological Laboratories) was administered intravenously. Clinical signs of EAE were assessed daily according to the following scores: 0, no clinical signs; 0.5, partially limp tail; 1, paralyzed ... (Shanghai) Ltd.] in Freund’s complete adjuvant containing heat-killed Mycobacterium tuberculosis H37Ra (5 mg/ml; BD Difco). On the day of immunization and 48 hours later, 200 ng of pertussis toxin (List Biological Laboratories) was administered intravenously. Clinical signs of EAE were assessed daily according to the following scores: 0, no clinical signs; 0.5, partially limp tail; 1, paralyzed

Proteome Profiling of Experimental Autoimmune Encephalomyelitis Mouse Model and the Effect of a SUMO E1 Inhibitor

Du, Y;Yang, L;Wang, X;Jiang, N;Zhou, Y;Chen, R;Li, H;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

  • MOG peptide (sequence: MEVGWYRSPFSRVVHLYRNGK) was purchased from GeneScript (Nanjing, Jiangsu, China), pertussis toxin was purchased from List Biological Laboratories (Campbell, California, USA), and Mycobacterium tuberculosis strain H37Ra and BD Inc

Engineered Immune Constructs Alter Antigen-Specific Immune Tolerance and Confer Durable Protection in Myelin-Driven Autoimmunity

Ackun-Farmmer, MA;Willson Shirkey, M;Oakes, RS;Shah, SA;Edwards, C;Kapnick, S;Carey, ST;Yanes, A;Bromberg, J;Jewell, CM;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

  • ratio (v/v) of 2 mg/mL MOG35-55 peptide in sterile 1x PBS and CFA. This mixture was emulsified using a probe sonicator (Qsonica, CL-18, and 1/8 in. probe, 4422) while on ice. Mice were anesthetized with isoflurane and injected with two 100 ?L emulsion injections along the midline. Two and 24 h later, mice were injected intraperitoneally (i.p.) with 60 ng of PTX (List Biological Laboratories). In male mouse studies, 40 ng of PTX was used. Clinical signs of disease were monitored accordingly: 0,