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#100B (1 mg)
$225.00
$330.00
$615.00
#112 (0.2 mg)
$595.00
#116L (Liquid)
$310.00
#122 (0.5 mg)
$475.00
#123 (0.25 mg)
$490.00
#126A (0.1 mg)
$360.00
$320.00
#130A (10ug), #130B (100ug)
$320.00 – $800.00
$320.00
#136A (10 ug), #136B (100 ug)
Botulinum Neurotoxin Type B, Nicked, from Clostridium botulinum
$300.00 – $1,000.00
#138B (100 ug), #138A (10 ug)
Botulinum Neurotoxin Type B Complex, Nicked, from Clostridium botulinum
$170.00 – $425.00
$400.00
#140A (10 ug), #140B (100 ug)
Botulinum Neurotoxin Type E Complex, Nicked, from Clostridium botulinum
$170.00 – $525.00
$475.00
$315.00
#149A (0.25 mg)
$475.00
$620.00
#151 (0.5 mg)
$670.00
#152C (100 ug)
$505.00
#155B (20 ug), 155L
$555.00 – $700.00
#156 (50 ug)
$500.00
#157A (20 ug)
$350.00
#159A (0.1 mg)
$290.00
#161 (10 ug)
$720.00
#162L (Liquid)
$680.00
$380.00
#171E (0.5 mg)
Anthrax Protective Antigen (PA), Recombinant from B. anthracis
Product # 171 is the entire 83 kDa native protein; This product contains the entire anthrax protective antigen 83 kDa native protein.$555.00
#172B (1 mg), #172L (1 mg),
$775.00 – $800.00
$980.00
#174 (0.5 mg)
Anthrax Protective Antigen, Activated (PA 63) from B. anthracis
Product # 174 is PA63, which has been created by enzymatic digestion and purified;$565.00
#175 (50 ug)
Anthrax PA 63 - FITC Conjugate
Product # 175 is purified PA63 conjugated to FITC for visualization.$425.00
#176A (1 mg), #176B (1 mg),
Anthrax Lethal Factor (LF), Recombinant, Mutant E687C from B. anthracis
$300.00 – $950.00
#177A (50 ug), #177B (.25mg),
Anthrax Protective Antigen Fragment (PA 20) from B. anthracis
Product # 177 is PA20, the approximately 20 kDA fragment cleaved from PA; and$350.00 – $670.00
#178A (0.1 mg)
$185.00
#179A (50 ug)
$310.00
$345.00
$345.00
#184 (50 ug)
$345.00
#186 (50 ug)
$370.00
#187 (50 ug)
$310.00
#188L (Liquid)
$320.00
#190A (25 ug), #190B (100 ug),
$180.00 – $580.00
#191A (25 ug), #191B (100 ug),
$305.00 – $880.00
#193 (10 ug)
$610.00
$415.00
#201 (5 mg)
$200.00
#203A (2.5 mg)
$200.00
#225 (5 mg)
$180.00
#301 (5 mg)
$180.00
#302 (5 mg)
$180.00
#304 (5 mg)
$180.00
#314 (1 mg)
$180.00
$210.00
#421 (1 mg)
$225.00
#423 (1 mg)
$235.00
#433 (1 mg)
$260.00
$215.00
$350.00
$350.00
$620.00
$515.00
$515.00
$515.00
#528 (50 nmoles)
Unquenched Calibration Peptide for SNAPtide® 521 Substrate for C. botulinum Type A Neurotoxin
$175.00
#529 (50 nmoles)
Unquenched Calibration Peptide for SNAPtide® 520 Substrate for C. botulinum Type A Neurotoxin
$175.00
#530 (200 nmoles)
MAPKKide® Peptide Substrate (o-Abz/Dnp) for Anthrax Lethal Factor
Product # 530 is MAPKKide® utilizing the o-Abz/Dnp FRET pair. A calibration peptide, Product #539 is available for convenient use with the quenched substrate.$310.00
#531 (200 nmoles)
MAPKKide® Peptide Substrate (DABCYL/FITC) for Anthrax Lethal Factor
Product # 531 is MAPKKide® with the FRET pair DABCYL/FITC.$310.00
#532 (100 nmoles)
MAPKKide® Plus (AMC) Specific Substrate for Anthrax Lethal Factor
Product # 532 is MAPKKide® Plus Specific Substrate for Anthrax Lethal Factor. This peptide is remarkable in its resistance to non-specific cleavage by enzymes which may be present in natural samples. MAPKKide® Plus carries the fluorophore 7-amido-4-methylcoumarin (AMC).$260.00
$175.00
#540 (200 nmoles)
VAMPtide® Peptide Substrate (o-Abz/Dnp) Substrate for C. botulinum Type B Neurotoxin
$515.00
#541 (200 nmoles)
VAMPtide® Peptide Substrate (FITC/DABCYL) Substrate for C. botulinum Type B Neurotoxin
$515.00
$515.00
#549 (100 nmoles)
Calibration Fluorophore for VAMPtide® 540 Substrate for C. botulinum Type B Neurotoxin
$175.00
$425.00
#559 (50 nmoles)
$260.00
$500.00
$280.00
$280.00
$280.00
#620A (10 ug)
$500.00
$280.00
$280.00
#625A (10 ug)
$500.00
#630A (10 ug)
$335.00
$430.00
#703 (0.1 ml)
$195.00
#730A (0.1 mg)
$350.00
$370.00
#752 (0.5 ml)
$195.00
#753A (0.1 mg)
$340.00
#754A (0.1 mg)
$340.00
$340.00
$350.00
$340.00
$340.00
#761L (Liquid)
$200.00
#766L (Liquid)
$350.00
#768L (Liquid)
Anti-B. anthracis Lethal Factor (LF-A), lgY Antibody, Biotinylated
Product # 768L affinity purified and biotinylated Anti-Lethal Factor from B. anthracis (chicken lgY) works to detect the LF as described in the C of A.$360.00
#769B (0.2 MG)
Anti-Lethal Factor from B. anthracis (Chicken lgY)
Product # 769B Anti-Lethal Factor from B. anthracis (chicken lgY) may be used to capture LF. Additionally, we have demonstrated that the antibody # 769B may be used to capture LF and use the MAPKKide®substrate.$500.00
#771B (1 mg)
Anti-Protective Antigen from B. anthracis (Goat)
Products # 771, purified IgG from goat, is directed to PA.$170.00
Prokineticin receptors interact unselectively with several G protein subtypes but bind selectively to β-arrestin 2
Cellular Signalling
Casella, I;Ambrosio, C;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
TIM-3 restrains anti-tumour immunity by regulating inflammasome activation
Nature
Dixon, KO;Tabaka, M;Schramm, MA;Xiao, S;Tang, R;Dionne, D;Anderson, AC;Rozenblatt-Rosen, O;Regev, A;Kuchroo, VK;
Product: Toxin A from Clostridium difficile
Human iPS cells engender corneal epithelial stem cells with holoclone-forming capabilities
iScience
Watanabe, S;Hayashi, R;Sasamoto, Y;Tsujikawa, M;Ksander, BR;Frank, MH;Quantock, AJ;Frank, NY;Nishida, K;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
An image-based flow cytometric approach to the assessment of the nucleus-to-cytoplasm ratio
PLOS One
Sebastian, JA;Moore, MJ;Berndl, ESL;Kolios, MC;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Spatiotemporally specific roles of TLR4, TNF, and IL-17A in murine endotoxin-induced inflammation inferred from analysis of dynamic networks
Molecular Medicine
Zamora, R;Chavan, S;Zanos, T;Simmons, RL;Billiar, TR;Vodovotz, Y;
Product: ULTRA PURE LPS from Escherichia coli O111:B4
A non-lethal murine flame burn model leads to a transient reduction in host defenses and enhanced susceptibility to lethal Pseudomonas aeruginosa infection
Infection and Immunity
Brammer, J;Choi, M;Baliban, SM;Kambouris, AR;Fiskum, G;Chao, W;Lopez, K;Miller, C;Al-Abed, Y;Vogel, SN;Simon, R;Cross, AS;
Product: LIPID A monophosphoryl from Salmonella minnesota R595
The Role of Posterior Pallial Amygdala in Mediating Motor Behavior in Pigeons
Research Square
Tian, X;Shi, Y;Zhang, Y;Wang, Y;Li, M;Cheng, H;Wang, Z;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
Structural basis for CSPG4 as a receptor for TcdB and a therapeutic target in Clostridioides difficile infection
Nature Communications
Chen, P;Zeng, J;Liu, Z;Thaker, H;Wang, S;Tian, S;Zhang, J;Tao, L;Gutierrez, CB;Xing, L;Gerhard, R;Huang, L;Dong, M;Jin, R;
Product: Anti-Clostridium difficile Toxin B (Chicken lgY)
Inhibition of cow’s milk allergy development in mice by oral delivery of ?-lactoglobulin-derived peptides loaded PLGA nanoparticles is associated with systemic whey-specific immune silencing
Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology
Liu, M;Thijssen, S;van Nostrum, CF;Hennink, WE;Garssen, J;Willemsen, LEM;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Ciliary GPCR?based transcriptome as a key regulator of cilia length control
FASEB BioAdvances
Kobayashi, Y;Tomoshige, S;Imakado, K;Sekino, Y;Koganezawa, N;Shirao, T;Diniz, G;Miyamoto, T;Saito, Y;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
Tissue-resident macrophages provide a pro-tumorigenic niche to early NSCLC cells
Nature
Casanova-Acebes, M;Dalla, E;Leader, AM;LeBerichel, J;Nikolic, J;Morales, BM;Brown, M;Chang, C;Troncoso, L;Chen, ST;Sastre-Perona, A;Park, MD;Tabachnikova, A;Dhainaut, M;Hamon, P;Maier, B;Sawai, CM;Agulló-Pascual, E;Schober, M;Brown, BD;Reizis, B;Marron, T;Kenigsberg, E;Moussion, C;Benaroch, P;Aguirre-Ghiso, JA;Merad, M;
Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae
Galectin-3 modulates microglia inflammation in vitro but not neonatal brain injury in vivo under inflammatory conditions
Developmental Neuroscience
Sävman, K;Wang, W;Rafati, AH;Svedin, P;Nair, S;Golubinskaya, V;Ardalan, M;Brown, KL;Karlsson-Bengtsson, A;Mallard, C;
Product: ULTRA PURE LPS from Escherichia coli O55:B5
A Novel Fatty Acid-Binding Protein 5 and 7 Inhibitor Ameliorates Oligodendrocyte Injury in Multiple Sclerosis Mouse Models
SSRN Electronic Journal
CHENG, A;Jia, W;Kawahata, I;Fukunaga, K;
Product: Pertussis Toxin from B. pertussis, Lyophilized (Salt-Free)
Appearance of Claudin-5+ Leukocyte Subtypes in the Blood and CNS During Progression of EAE
Research Square
Krajewski, D;Paul, D;Ge, S;Jellison, E;Pachter, J;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
Structural specificities of cell surface β-glucan polysaccharides determine commensal yeast mediated immuno-modulatory activities
Nature Communications
Lee, C;Verma, R;Byun, S;Jeun, EJ;Kim, GC;Lee, S;Kang, HJ;Kim, CJ;Sharma, G;Lahiri, A;Paul, S;Kim, KS;Hwang, DS;Iwakura, Y;Speciale, I;Molinaro, A;De Castro, C;Rudra, D;Im, SH;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
Label-free and Rapid Detection of Anthrax Protective Antigen by Surface-enhanced Raman Scattering on Au Nanorods
IEEE Sensors Journal
Li, B;Wang, T;Bai, W;Su, Q;Wu, X;Dong, P;
Product: Anthrax Protective Antigen (PA), Recombinant from B. anthracis
Deciphering an AgRP-serotoninergic neural circuit in distinct control of energy metabolism from feeding
Nature Communications
Han, Y;Xia, G;Srisai, D;Meng, F;He, Y;Ran, Y;He, Y;Farias, M;Hoang, G;Tóth, I;Dietrich, MO;Chen, MH;Xu, Y;Wu, Q;
Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae
Distinctive waves of innate immune response in the retina in experimental autoimmune encephalomyelitis
JCI insight
Cruz-Herranz, A;Oertel, FC;Kim, K;Cantó, E;Timmons, G;Sin, JH;Devereux, M;Baker, N;Michel, B;Schubert, RD;Rani, L;Cordano, C;Baranzini, SE;Green, AJ;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
Hemolysis-associated phosphatidylserine exposure promotes polyclonal plasmablast differentiation
The Journal Of Experimental Medicine
Vijay, R;Guthmiller, JJ;Sturtz, AJ;Crooks, S;Johnson, JT;Li, L;Lan, LY;Pope, RL;Chen, Y;Rogers, KJ;Dutta, N;Toombs, JE;Wilson, ME;Wilson, PC;Maury, W;Brekken, RA;Butler, NS;
Product: Anthrax Protective Antigen (PA), Recombinant from B. anthracis
Brain gray matter astroglia-specific connexin 43 ablation attenuates spinal cord inflammatory demyelination
Journal of Neuroinflammation
Une, H;Yamasaki, R;Nagata, S;Yamaguchi, H;Nakamuta, Y;Indiasari, UC;Cui, Y;Shinoda, K;Masaki, K;Götz, M;Kira, JI;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
Involvement of microRNA-155 in the mechanism of electroacupuncture treatment effects on experimental autoimmune encephalomyelitis
International Immunopharmacology
Zhao, P;Chen, X;Han, X;Wang, Y;Shi, Y;Ji, J;Lei, Y;Liu, Y;Kong, Q;Mu, L;Wang, J;Zhao, W;Wang, G;Liu, X;Zhang, T;Zhang, Y;Sun, B;Liu, Y;Li, H;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
Skull and vertebral bone marrow are myeloid cell reservoirs for the meninges and CNS parenchyma
Science
Cugurra, A;Mamuladze, T;Rustenhoven, J;Dykstra, T;Beroshvili, G;Greenberg, ZJ;Baker, W;Papadopoulos, Z;Drieu, A;Blackburn, S;Kanamori, M;Brioschi, S;Herz, J;Schuettpelz, LG;Colonna, M;Smirnov, I;Kipnis, J;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
Ghrelin Treatment Induces Rapid and Delayed Increments of Food Intake: A Heuristic Model to Explain Ghrelins Orexigenic Effects
Research Square
Cornejo, M;Denis, R;Romero, G;Fernandez, G;Reynaldo, M;Luquet, S;Perello, M;
Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae
Targeted Expression of Myelin Autoantigen in the Periphery Induces Antigen-Specific T and B Cell Tolerance and Ameliorates Autoimmune Disease
Frontiers In Immunology
Na, SY;Krishnamoorthy, G;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
Insufficient Anthrax Lethal Toxin Neutralization Is Associated with Antibody Subclass and Domain Specificity in the Plasma of Anthrax-Vaccinated Individuals
Microorganisms
Smith, K;Garman, L;Norris, K;Muther, J;Duke, A;Engler, RJM;Nelson, MR;Collins, LC;Spooner, C;Guthridge, C;James, JA;
Product: Anthrax Protective Antigen (PA), Recombinant from B. anthracis
m6A demethylase ALKBH5 controls CD4+ T cell pathogenicity and promotes autoimmunity
Science Advances
Zhou, J;Zhang, X;Hu, J;Qu, R;Yu, Z;Xu, H;Chen, H;Yan, L;Ding, C;Zou, Q;Ye, Y;Wang, Z;Flavell, RA;Li, HB;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
Type 17 immunity promotes the exhaustion of CD8+ T cells in cancer
Journal For Immunotherapy Of Cancer
Kim, BS;Kuen, DS;Koh, CH;Kim, HD;Chang, SH;Kim, S;Jeon, YK;Park, YJ;Choi, G;Kim, J;Kang, KW;Kim, HY;Kang, SJ;Hwang, S;Shin, EC;Kang, CY;Dong, C;Chung, Y;
Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae
Effect of Preexisting Immunity to Tetanus Toxoid on the Efficacy of Tetanus Toxoid-Conjugated Heroin Vaccine in Mice
Vaccines
Komla, E;Torres, OB;Jalah, R;Sulima, A;Beck, Z;Alving, CR;Jacobson, AE;Rice, KC;Matyas, GR;
Product: Diphtheria Toxoid, from Corynebacterium diphtheriae
RRx-001 ameliorates inflammatory diseases by acting as a potent covalent NLRP3 inhibitor
Cellular & Molecular Immunology
Chen, Y;He, H;Lin, B;Chen, Y;Deng, X;Jiang, W;Zhou, R;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
Type I interferon decreases macrophage energy metabolism during mycobacterial infection
Cell Reports
Olson, GS;Murray, TA;Jahn, AN;Mai, D;Diercks, AH;Gold, ES;Aderem, A;
Product: LPS from Salmonella minnesota R595 (Re)
The LINC01119-SOCS5 axis as a critical theranostic in triple-negative breast cancer
NPJ Breast Cancer
Tu, Z;Schmoellerl, J;Mariani, O;Zheng, Y;Hu, Y;Vincent-Salomon, A;Karnoub, AE;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Olaparib attenuates sepsis-induced acute multiple organ injury via ERK-mediated CD14 expression
Experimental Biology And Medicine
Chen, Z;Chen, Y;Jin, X;Liu, Y;Shao, Z;Li, Q;
Product: LPS from Escherichia coli O55:B5
The CD44/COL17A1 pathway promotes the formation of multilayered, transformed epithelia
Current Biology : CB
Kozawa, K;Sekai, M;Ohba, K;Ito, S;Sako, H;Maruyama, T;Kakeno, M;Shirai, T;Kuromiya, K;Kamasaki, T;Kohashi, K;Tanaka, S;Ishikawa, S;Sato, N;Asano, S;Suzuki, H;Tanimura, N;Mukai, Y;Gotoh, N;Tanino, M;Tanaka, S;Natsuga, K;Soga, T;Nakamura, T;Yabuta, Y;Saitou, M;Ito, T;Matsuura, K;Tsunoda, M;Kikumori, T;Iida, T;Mizutani, Y;Miyai, Y;Kaibuchi, K;Enomoto, A;Fujita, Y;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
A critical role for Th17 cell-derived TGF-β1 in regulating the stability and pathogenicity of autoimmune Th17 cells
Experimental & Molecular Medicine
Choi, G;Park, YJ;Cho, M;Moon, H;Kim, D;Kang, CY;Chung, Y;Kim, BS;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
Annexin Induces Cellular Uptake of Extracellular Vesicles and Delays Disease in Escherichia coli O157:H7 Infection
Microorganisms
Tontanahal, A;Arvidsson, I;Karpman, D;
Product: Anti-Shiga Toxin, Camelid Antibody, VHH
Oral anaphylaxis to peanut in a mouse model is associated with gut permeability but not with Tlr4 or Dock8 mutations
The Journal Of Allergy And Clinical Immunology
Gertie, JA;Zhang, B;Liu, EG;Hoyt, LR;Yin, X;Xu, L;Long, LL;Soldatenko, A;Gowthaman, U;Williams, A;Eisenbarth, SC;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
MeCP2 deficiency exacerbates the neuroinflammatory setting and autoreactive response during an autoimmune challenge
Scientific Reports
Zalosnik, MI;Fabio, MC;Bertoldi, ML;Castañares, CN;Degano, AL;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
A mutant equipped with a regenerated disulfide for the missing his loop of a serine protease zymogen in the horseshoe crab coagulation cascade
Journal Of Biochemistry
Yamashita, K;Takeshita, N;Arita, A;Shibata, T;Kobayashi, Y;Kawabata, SI;
Product: LPS from Salmonella minnesota R595 (Re)
Hydrophobic Gating and 1/f Noise of the Anthrax Toxin Channel
The Journal Of Physical Chemistry. B
Yamini, G;Kanchi, S;Kalu, N;Momben Abolfath, S;Leppla, SH;Ayappa, KG;Maiti, PK;Nestorovich, EM;
Product: Anthrax Protective Antigen (PA), Recombinant from B. anthracis
Gβγ translocation to the Golgi apparatus activates ARF1 to spatiotemporally regulate G protein–coupled receptor signaling to MAPK
The Journal Of Biological Chemistry
Khater, M;Bryant, CN;Wu, G;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
G?? translocation to the Golgi apparatus activates ARF1 to spatiotemporally regulate G protein-coupled receptor signaling to MAPK
The Journal Of Biological Chemistry
Khater, M;Bryant, CN;Wu, G;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
Stabilin Receptors Clear LPS and Control Systemic Inflammation
Ssrn Electronic Journal
Cabral, F;Skaggs, J;Al-Rahem, M;Thomas, T;Kumar, N;Wu, Q;Fadda, P;Yu, L;Robinson (Late), J;Kim, J;Jarjour, W;Rajaram, M;Harris, E;Ganesan, L;
Product: LPS from Escherichia coli K12 strain LCD25
Avian adeno-associated virus as an anterograde transsynaptic vector
Journal Of Neuroscience Methods
Ito, T;Ono, M;Matsui, R;Watanabe, D;Ohmori, H;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
A systematic assessment of the relationship between synthetic surfactants and mucosal adjuvanticity
European Journal Of Pharmaceutics And Biopharmaceutics : Official Journal Of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V
Yoshino, N;Kawamura, H;Sugiyama, I;Sasaki, Y;Odagiri, T;Sadzuka, Y;Muraki, Y;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
SLFN2 protection of tRNAs from stress-induced cleavage is essential for T cell-mediated immunity
Science
Yue, T;Zhan, X;Zhang, D;Jain, R;Wang, KW;Choi, JH;Misawa, T;Su, L;Quan, J;Hildebrand, S;Xu, D;Li, X;Turer, E;Sun, L;Moresco, EMY;Beutler, B;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
4-Ethylguaiacol modulates neuroinflammation and Th1/Th17 differentiation to ameliorate disease severity in experimental autoimmune encephalomyelitis
Journal Of Neuroinflammation
Weng, WT;Kuo, PC;Brown, DA;Scofield, BA;Furnas, D;Paraiso, HC;Wang, PY;Yu, IC;Yen, JH;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
Glycolytic ATP fuels phosphoinositide 3-kinase signaling to support effector T helper 17 cell responses
Immunity
Xu, K;Yin, N;Peng, M;Stamatiades, EG;Chhangawala, S;Shyu, A;Li, P;Zhang, X;Do, MH;Capistrano, KJ;Chou, C;Leslie, CS;Li, MO;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
YAP promotes the activation of NLRP3 inflammasome via blocking K27-linked polyubiquitination of NLRP3
Nature Communications
Wang, D;Zhang, Y;Xu, X;Wu, J;Peng, Y;Li, J;Luo, R;Huang, L;Liu, L;Yu, S;Zhang, N;Lu, B;Zhao, K;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
A photoswitchable GPCR-based opsin for presynaptic inhibition
Neuron
Copits, BA;Gowrishankar, R;O'Neill, PR;Li, JN;Girven, KS;Yoo, JJ;Meshik, X;Parker, KE;Spangler, SM;Elerding, AJ;Brown, BJ;Shirley, SE;Ma, KKL;Vasquez, AM;Stander, MC;Kalyanaraman, V;Vogt, SK;Samineni, VK;Patriarchi, T;Tian, L;Gautam, N;Sunahara, RK;Gereau, RW;Bruchas, MR;
Product: Pertussis Toxin from B. pertussis (in Glycerol)
Respiratory axon regeneration in the chronically injured spinal cord
Neurobiology Of Disease
Cheng, L;Sami, A;Ghosh, B;Goudsward, HJ;Smith, GM;Wright, MC;Li, S;Lepore, AC;
Product: Anti-Cholera Toxin B Subunit (Goat)
IgE-activated mast cells enhance TLR4-mediated antigen-specific CD4+ T cell responses
Scientific Reports
Phong, BL;D'Souza, SJ;Baudier, RL;Wu, E;Immethun, VE;Bauer, DL;McLachlan, JB;
Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae
Downregulation of DUOX1 function contributes to aging-related impairment of innate airway injury responses and accelerated senile emphysema
American Journal Of Physiology. Lung Cellular And Molecular Physiology
Schiffers, C;Lundblad, LKA;Hristova, M;Habibovic, A;Dustin, CM;Daphtary, N;Aliyeva, M;Seward, DJ;Janssen-Heininger, YMW;Wouters, EFM;Reynaert, NL;van der Vliet, A;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Selection of a picomolar antibody that targets CXCR2-mediated neutrophil activation and alleviates EAE symptoms
Nature Communications
Shi, X;Wan, Y;Wang, N;Xiang, J;Wang, T;Yang, X;Wang, J;Dong, X;Dong, L;Yan, L;Li, Y;Liu, L;Hou, S;Zhong, Z;Wilson, IA;Yang, B;Yang, G;Lerner, RA;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
Effect of dental malocclusion on cerebellar neuron activation via the dorsomedial part of the principal sensory trigeminal nucleus
European Journal Of Oral Sciences
Shi, M;Liu, X;Zhang, C;Zhang, H;Liu, Q;Wang, D;Liu, X;Li, J;Wang, M;
Product: Anti-Cholera Toxin B Subunit (Goat)
HDAC8 Activates AKT through Upregulating PLCB1 and Suppressing DESC1 Expression in MEK1/2 Inhibition-Resistant Cells
Cells
Ha, SD;Lewin, N;Li, SSC;Kim, SO;
Product: Anthrax Protective Antigen (PA), Recombinant from B. anthracis
ADAM9 enhances Th17 cell differentiation and autoimmunity by activating TGF-?1
Proceedings Of The National Academy Of Sciences Of The United States Of America
Umeda, M;Yoshida, N;Hisada, R;Burbano, C;Orite, SYK;Kono, M;Kyttaris, VC;Krishfield, S;Owen, CA;Tsokos, GC;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
Quinoa (Chenopodium quinoa Willd.) Seeds Increase Intestinal Protein Uptake
Molecular Nutrition & Food Research
Ballegaard, AR;Larsen, JM;Rasmussen, PH;Untersmayr, E;Pilegaard, K;Bøgh, KL;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
AIM2 controls microglial inflammation to prevent experimental autoimmune encephalomyelitis
The Journal Of Experimental Medicine
Ma, C;Li, S;Hu, Y;Ma, Y;Wu, Y;Wu, C;Liu, X;Wang, B;Hu, G;Zhou, J;Yang, S;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
Antigen-encapsulating host extracellular vesicles derived from Salmonella-infected cells stimulate pathogen-specific Th1-type responses in vivo
Plos Pathogens
Hui, WW;Emerson, LE;Clapp, B;Sheppe, AE;Sharma, J;Del Castillo, J;Ou, M;Maegawa, GHB;Hoffman, C;Larkin Iii, J;Pascual, DW;Edelmann, MJ;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
Macrophage migration inhibitory factor promotes the migration of dendritic cells through CD74 and the activation of the Src/PI3K/myosin II pathway
FASEB Journal : Official Publication Of The Federation Of American Societies For Experimental Biology
Ives, A;Le Roy, D;Théroude, C;Bernhagen, J;Roger, T;Calandra, T;
Product: ULTRA PURE LPS from Salmonella minnesota R595 (Re)
A novel single-domain antibody multimer that potently neutralizes tetanus neurotoxin
Vaccine: X
de Smit Conceptualisation, H;Ackerschott, B;Tierney, R;Stickings, P;Harmsen Conceptualisation, M;
Product: Tetanus Toxin from Clostridium tetani
Conditional Deletions of Hdc Confirm Roles of Histamine in Anaphylaxis and Circadian Activity but Not in Autoimmune Encephalomyelitis
Journal Of Immunology
Morin, F;Singh, N;Mdzomba, JB;Dumas, A;Pernet, V;Vallières, L;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
CNS Autoimmune Responses in BCMA-Deficient Mice Provide Insight for the Failure of Atacicept in MS
Neurology(R) Neuroimmunology & Neuroinflammation
Kumar, G;Maria, Z;Kohli, U;Agasing, A;Quinn, JL;Ko, RM;Zamvil, SS;Axtell, RC;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
STING Agonist Mitigates Experimental Autoimmune Encephalomyelitis by Stimulating Type I IFN-Dependent and -Independent Immune-Regulatory Pathways
Journal Of Immunology
Johnson, BM;Uchimura, T;Gallovic, MD;Thamilarasan, M;Chou, WC;Gibson, SA;Deng, M;Tam, JW;Batty, CJ;Williams, J;Matsushima, GK;Bachelder, EM;Ainslie, KM;Markovic-Plese, S;Ting, JP;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
LRRC4 functions as a neuron-protective role in experimental autoimmune encephalomyelitis
Molecular Medicine (Cambridge, Mass.)
Zhang, Y;Li, D;Zeng, Q;Feng, J;Fu, H;Luo, Z;Xiao, B;Yang, H;Wu, M;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
Glucan particles as a novel adjuvant for the induction of experimental autoimmune encephalomyelitis
Cellular Immunology
Huizar, C;Ji, N;Reddick, R;Ostroff, G;Forsthuber, T;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
Four single-basepair mutations in the ptx promoter of Bordetella bronchiseptica are sufficient to activate the expression of pertussis toxin
Scientific Reports
Chen, Q;Gray, MC;Hewlett, E;Stibitz, S;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
Developing a Novel Multiplexed Immune Assay Platform to Screen Kinase Modulators of T Cell Activation
High-Throughput Screening For Drug Discovery
Liu, Z;Gomez-Donart, A;Weldon, C;Senutovitch, N;ORourke, J;
Product: Enterotoxin Type B from Staphylococcus aureus
T cell immune discriminants of HIV reservoir size in a pediatric cohort of perinatally infected individuals
Plos Pathogens
Rinaldi, S;de Armas, L;Dominguez-Rodríguez, S;Pallikkuth, S;Dinh, V;Pan, L;G?rtner, K;Pahwa, R;Cotugno, N;Rojo, P;Nastouli, E;Klein, N;Foster, C;De Rossi, A;Giaquinto, C;Rossi, P;Palma, P;EPIICAL consortium, ;
Product: Enterotoxin Type B from Staphylococcus aureus
Suppression of neuroinflammation by an allosteric agonist and positive allosteric modulator of the ?7 nicotinic acetylcholine receptor GAT107
Journal Of Neuroinflammation
Mizrachi, T;Marsha, O;Brusin, K;Ben-David, Y;Thakur, GA;Vaknin-Dembinsky, A;Treinin, M;Brenner, T;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
Characterisation of tetanus monoclonal antibodies as a first step towards the development of an in vitro vaccine potency immunoassay
Biologicals : Journal Of The International Association Of Biological Standardization
Riches-Duit, R;Hassall, L;Kogelman, A;Westdijk, J;Rajagopal, S;Davletov, B;Doran, C;Dobly, A;Francotte, A;Stickings, P;
Product: Tetanus Toxin from Clostridium tetani
S1P2-Gα12 signaling inhibits astrocytic glutamate uptake and mitochondrial oxygen consumption
Eneuro
Jonnalagadda, D;Kihara, Y;Rivera, R;Chun, J;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
Construction and evaluation of a pertactin-deficient live attenuated pertussis vaccine candidate BPZE1 derivative
Vaccine
Solans, L;Debrie, AS;Coutte, L;Locht, C;
Product: Pertactin from B. pertussis (69 kDa Protein)
Immunisation with the BCG and DTPw vaccines induces different programs of trained immunity in mice
Vaccine
Stevens, NE;van Wolfswinkel, M;Bao, W;Ryan, FJ;Brook, B;Amenyogbe, N;Marshall, HS;Lynn, MA;Kollmann, TR;Tumes, DJ;Lynn, DJ;
Product: Diphtheria Toxoid, from Corynebacterium diphtheriae
Temporal overexpression of IL-22 and Reg3γ differentially impacts the severity of experimental autoimmune encephalomyelitis
Immunology
Eken, A;Erdem, S;Haliloglu, Y;Zehra Okus, F;Cakir, M;Fatih Yetkin, M;Akcakoyunlu, M;Karayigit, MO;Azizoglu, ZB;Bicer, A;Gur, TN;Aslan, K;Hora, M;Oukka, M;Altuntas, HD;Ufuk Nalbantoglu, O;Gundogdu, A;Mirza, M;Canatan, H;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
Temporal overexpression of IL-22 and Reg3? differentially impacts the severity of experimental autoimmune encephalomyelitis
Immunology
Eken, A;Erdem, S;Haliloglu, Y;Zehra Okus, F;Cakir, M;Fatih Yetkin, M;Akcakoyunlu, M;Karayigit, MO;Azizoglu, ZB;Bicer, A;Gur, TN;Aslan, K;Hora, M;Oukka, M;Altuntas, HD;Ufuk Nalbantoglu, O;Gundogdu, A;Mirza, M;Canatan, H;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
Dual Regeneration of Muscle and Nerve by Intramuscular Infusion of Mitochondria in a Nerve Crush Injury Model
Neurosurgery
Sheu, ML;Shen, CC;Tsou, HK;Yang, MY;Su, HL;Sheehan, J;Chang, MH;Chen, HS;Pan, HC;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
Neuromedin U uses Gαi2 and Gαo to suppress glucose-stimulated Ca2+ signaling and insulin secretion in pancreatic β cells
Plos One
Zhang, W;Sakoda, H;Nakazato, Y;Islam, MN;Pattou, F;Kerr-Conte, J;Nakazato, M;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
Baricitinib Ameliorates Experimental Autoimmune Encephalomyelitis by Modulating the Janus Kinase/Signal Transducer and Activator of Transcription Signaling Pathway
Frontiers In Immunology
Dang, C;Lu, Y;Chen, X;Li, Q;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
Genome-wide screens uncover KDM2B as a modifier of protein binding to heparan sulfate
Nature Chemical Biology
Weiss, RJ;Spahn, PN;Chiang, AWT;Liu, Q;Li, J;Hamill, KM;Rother, S;Clausen, TM;Hoeksema, MA;Timm, BM;Godula, K;Glass, CK;Tor, Y;Gordts, PLSM;Lewis, NE;Esko, JD;
Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae
Human in vivo neuroimaging to detect reprogramming of the cerebral immune response following repeated systemic inflammation
Brain, Behavior, And Immunity
Peters van Ton, AM;Leijte, GP;Franssen, GM;Bruse, N;Booij, J;Doorduin, J;Rijpkema, M;Kox, M;Abdo, WF;Pickkers, P;
Product: LIST™ HPT™ from Escherichia coli O113
Clostridioides difficile toxins enhanced the in vitro production of CXC chemokine ligand 2 and tumor necrosis factor-α via Toll-like receptors in macrophages
Journal Of Medical Microbiology
McKee, HK;Kajiwara, C;Yamaguchi, T;Ishii, Y;Shimizu, N;Ohara, A;Tateda, K;
Product: Toxin B from Clostridium difficile
Cathepsin L regulates pathogenic CD4 T cells in experimental autoimmune encephalomyelitis
International Immunopharmacology
Shibamura-Fujiogi, M;Yuki, K;Hou, L;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
Dual motor cortex and spinal cord neuromodulation improves rehabilitation efficacy and restores skilled locomotor function in a rat cervical contusion injury model
Experimental Neurology
Sharif, H;Alexander, H;Azam, A;Martin, J;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
Strain and sex differences in somatosensation and sociability during experimental autoimmune encephalomyelitis
Brain, Behavior, & Immunity - Health
Ondek, K;Nasirishargh, A;Dayton, J;Nuño, M;Cruz-Orengo, L;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
Assessing the Association of Mitochondrial Function and Inflammasome Activation in Murine Macrophages Exposed to Select Mitotoxic Tri-Organotin Compounds
Environmental Health Perspectives
Childers, GM;Perry, CA;Blachut, B;Martin, N;Bortner, CD;Sieber, S;Li, JL;Fessler, MB;Harry, GJ;
Product: ULTRA PURE LPS from Escherichia coli O111:B4
Complementary biosensors reveal different G-protein signaling modes triggered by GPCRs and non-receptor activators
Elife
Garcia-Marcos, M;
Product: Pertussis Toxin from B. pertussis (in Glycerol)
The mechanism of grape seed oligomeric procyanidins in the treatment of experimental autoimmune encephalomyelitis mice
Research Square
Xue, L;Wang, Q;Ding, Z;Miao, Q;Li, Y;Song, L;Li, Y;Yu, J;Wang, Y;Ma, C;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
Protection from Lethal Clostridioides difficile Infection via Intraspecies Competition for Cogerminant
mBio
Leslie, JL;Jenior, ML;Vendrov, KC;Standke, AK;Barron, MR;O'Brien, TJ;Unverdorben, L;Thaprawat, P;Bergin, IL;Schloss, PD;Young, VB;
Product: Toxin A from Clostridium difficile
Endotoxin acts synergistically with C. difficile toxin B to increase IL-1 ? production: A potential role for the intestinal biome in modifying the severity of C. difficile colitis
The Journal Of Infectious Diseases
Htwe, P;Aung, HH;Kywe, B;Niang, PT;Oo, TS;Monhandas, S;Kelly, L;Goldman, DL;
Product: Toxin B from Clostridium difficile
Dual function of a turbot inflammatory caspase in mediating both canonical and non-canonical inflammasome activation
Developmental And Comparative Immunology
Chen, S;Jin, P;Chen, H;Wu, D;Li, S;Zhang, Y;Liu, Q;Yang, D;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
CTRP4 binds to the interleukin-6 Receptor and ameliorates autoimmune encephalomyelitis by suppressing Th17 cell differentiation
Research Square
Cao, L;Chen, W;Na, D;Huang, H;Li, Q;Zhu, X;Wang, L;
Product: Pertussis Toxin from B. pertussis (in Glycerol)
C-Reactive Protein Suppresses the Th17 Response Indirectly by Attenuating the Antigen Presentation Ability of Monocyte Derived Dendritic Cells in Experimental Autoimmune Encephalomyelitis
Frontiers In Immunology
Shen, Z;Zheng, Y;Pecsok, M;Wang, K;Li, W;Gong, M;Wu, F;Zhang, L;
Product: Pertussis Toxin from B. pertussis, Lyophilized (Salt-Free)
The Regulatory Subunit PPP2R2A of PP2A Enhances Th1 and Th17 Differentiation through Activation of the GEF-H1/RhoA/ROCK Signaling Pathway
Journal Of Immunology
Pan, W;Nagpal, K;Suárez-Fueyo, A;Ferretti, A;Yoshida, N;Tsokos, MG;Tsokos, GC;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
Phagocytosis of microparticles increases responsiveness of macrophage-like cell lines U937 and THP-1 to bacterial lipopolysaccharide and lipopeptide
Scientific Reports
Ueno, T;Yamamoto, Y;Kawasaki, K;
Product: LPS from Escherichia coli O111:B4
Exploiting Rational Assembly to Map Distinct Roles of Regulatory Cues during Autoimmune Therapy
ACS Nano
Oakes, RS;Tostanoski, LH;Kapnick, SM;Froimchuk, E;Black, SK;Zeng, X;Jewell, CM;
Product: Pertussis Toxin from B. pertussis (in Glycerol)
Projections from the ventral nucleus of the lateral lemniscus to the cochlea in the mouse
The Journal Of Comparative Neurology
Suthakar, K;Ryugo, DK;
Product: Anti-Cholera Toxin B Subunit (Goat)
Development of a competitive inhibition kinetic ELISA to determine the inhibition constant (Ki) of monoclonal antibodies
Journal Of Immunological Methods
Toraño, A;Moreno, I;Infantes, JA;Domínguez, M;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Nonpeptidergic neurons suppress mast cells via glutamate to maintain skin homeostasis
Cell
Zhang, S;Edwards, TN;Chaudhri, VK;Wu, J;Cohen, JA;Hirai, T;Rittenhouse, N;Schmitz, EG;Zhou, PY;McNeil, BD;Yang, Y;Koerber, HR;Sumpter, TL;Poholek, AC;Davis, BM;Albers, KM;Singh, H;Kaplan, DH;
Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae
Ginsenoside Rd attenuates mouse experimental autoimmune neuritis by modulating monocyte subsets conversion
Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie
Ren, K;Li, S;Ding, J;Zhao, S;Liang, S;Cao, X;Su, C;Guo, J;
Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer
July 23, 2018
By: Mary N. Wessling, Ph.D. ELS In this blog we will unravel the terminology describing bacterial toxins. In general, there are at least three ways that bacterial toxins are described in the literature: by their biological designation—the genus and/or species from which they come by the origin of the toxin, either as innate to the […]
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