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Toxin A from Clostridium difficile

Toxin A from Clostridium difficile

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Products are for research purposes only and are
not for use in humans or as diagnostic agents.

View our other C. difficile Toxins Products

$650.00

#152C (100 ug)

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Technical Info

Certificate Of Analysis

SDS / MSDS

Purity

>80%

Form

lyophilized powder

Storage temp

2-8°C

Additional information

Weight N/A
Dimensions N/A
Destination

,

We have 72 citations
Phenotypic profiling of neutrophils in acute Clostridioides difficile infection identifies a TNF-induced activation signature associated with epithelial damage
Huber, Mathew, Khondokar et al
Gut Microbes (2026) 18 (1), 2659430 DOI: 10.1080/19490976.2026.2659430
Snippet: … Concentration of various stimuli used is based on published literature and pilot studies done in our lab: C. difficile toxins A and B (5?ng/ml each; List Biologicals #152C and #155L), …
FigureFigureFigure
An N-terminal CDC42 T43I variant reveals the mechanism of pyrin inflammasome activation
Aoki, Iannuzzo, Mertz et al
Sci Immunol (2026) 11 (122), eaea0515 DOI: 10.1126/sciimmunol.aea0515
Cited by 4
Snippet: … After 2 hours of LPS priming, TcdA (1 μg/ml; List Biological Laboratories, no. 152C) was added and the supernatants …
Adenosine deaminase co-immunization reverses age-associated immunosenescence by restoring germinal center T follicular helper cell function
Bitsko, Joyner, Maslanka et al
bioRxiv (2026)
Snippet: … To determine the neutralization capacity of vaccine-induced antibodies in mouse sera, Vero cells were propagated in complete DMEM (cDMEM) and plated at 8,000 cells/well in Nunc MicroWell 96-Well Black Optical-Bottom Plates (Thermo Scientific, Cat: 12-566-70). Following 37°C incubation for 24 hours (∼90% confluency), serum dilutions for individual mice were prepared and incubated with 60ng/mL Toxin A (List Biological Laboratories Inc., Cat: 152C) for 90 minutes at 37°C. ...
Oral co-exposure to Clostridioides difficile toxin A and ovalbumin disrupts intestinal homeostasis and predisposes to food allergy in mice
Xu, Zeng, Cheng et al
Toxicon (2026) 275, 109052 DOI: 10.1016/j.toxicon.2026.109052
Snippet: TcdA was purchased from List Biological Laboratories Inc (Campbell, CA, USA).
Construction of an electrochemical aptasensor based on DNA walker and redox capacitor for ultrasensitive detection of Clostridium difficile toxin B
Chen, Fu, Wu et al
Electrochimica Acta (2026) 551, 148178-148178 DOI: 10.1016/j.electacta.2026.148178
Snippet: - Clostridium difficile infection (CDI) has become a pressing global health challenge, with increasing incidence, recurrence, and mortality in both healthcare and community …;0mg/mL) was purchased from Thermofisher scientific, Inc; TcdB and TcdA were purchased from List Biological Laboratories Inc.(USA); GDH was purchased from Meridian Bioscience Inc.(VIVO.USA); Nt.AlwI
High-fat diet rewires gut host-microbiota relationship to derive worse outcomes following Clostridioides difficile infection
Kumar, Nguyen, O'Brien et al
bioRxiv (2026)
Snippet: … The activity of toxins in cecal samples is compared with a standard curve using C. difficile toxin A (List Biological Labs).4.5MicrobiotaTo investigate the microbiota of ND- and HFD-fed male and female mice at baseline, we collected fec ... …difficile toxin A (List Biological Labs).4.5MicrobiotaTo investigate the microbiota of ND- and HFD-fed male and female mice at baseline, we collected fec
FigureFigureFigure
Experimental glycopeptide antibiotic EVG7 prevents recurrent Clostridioides difficile infection by sparing members of the Lachnospiraceae family
Mons, Henderickx, Sanders et al
Nat Commun (2025) 16 (1), 9017 DOI: 10.1038/s41467-025-64067-w
Cited by 3
Snippet: Vero cells treated with purified C. difficile toxin A (List Biological Labs, 152?C) were used as controls. …
FigureFigureFigure
Temporally segregated subpopulations of CDT and TcdA producer cells of Clostridioides difficile
Ramalhete, Roseiro, Cassona et al
mSphere (2025) 10 (9), e0018625 DOI: 10.1128/msphere.00186-25
Cited by 1
Snippet: ... Brilliant Blue R-250, or subject to immunoblot analysis with an anti-TcdA antibody at a dilution of 1:5,000 (from Santa Cruz Biotechnology), an anti-CdtA antibody at a dilution of 1:5,000 (from List Biological Laboratories), or an anti-SNAP antibody at a dilution of 1:1,000 (from New England Biolabs). The following secondary antibodies conjugated to horseradish peroxidase were used: ...
Half-Pipe Melt Electrowritten Scaffolds Support Engineering of an Immunocompetent Hydrogel-Embedded Intestine-on-a-Chip
Janssen, Schulze, Nelissen et al
Adv Sci (Weinh) (2025)
Cited by 4
Snippet: lly exposed to OVA (100 µg mL−1), Ara h 2 (100 µg mL−1) or BLG (100 µg mL−1), hypo-allergen Rubisco (100 µg mL−1), or exposed to toxin A derived from gram-positive bacterium C. difficile (toxin A, List Biological Labs, Inc, 152C; 0.065 µg mL−1) combined with LPS (100 ng mL−1). …
Clostridioides difficile Toxins Alter Host Metabolic Pathway and Bile Acid Homeostasis Gene Expression In Colonic Epithelium
Thomas, Pike, Perkins et al
bioRxiv (2025)
Snippet: S and filtered with a 0.22 μm filter. Filtrates were added to wells seeded with 104 cells per well and incubated overnight. Toxin A from VPI 10463 was used as a positive control and antitoxin (List Labs 152C, and TechLab, T5003) was used to quench activity. RNA isolation and gene expression analysis
Showing 1-10 of 72 papers.
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