Citations

Bacterial Toxin Research Citations

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4868 citations found

Immunization with an mRNA DTP vaccine protects against pertussis in rats

Bitzer, GJ;Fitzgerald, NA;DeJong, MA;Cunningham, C;Chapman, JA;Boehm, DT;Pyles, GM;Huckaby, AB;Miller, SJ;Dublin, SR;Warden, MD;Barbier, M;Damron, FH;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

  • Plates were coated with 50 µL per well of either whole PT (List Biological Laboratories; cat#180) or an individual subunit of PT synthesized by GenScript Biotech (PTxA, B,

Gut-specific H3R signaling orchestrates microglia-dependent resolution of peripheral inflammation

Dürholz, K;Linnerbauer, M;Schmid, E;Danzer, H;Lößlein, L;Amend, L;Ehnes, L;Frech, M;Azizov, V;Schälter, F;Gessner, A;Lucas, S;Lesker, T;Taudte, R;Hofmann, J;Beyer, F;Bootz-Maoz, H;Reich, Y;Romano, H;Mauro, D;Beckervordersandforth, R;Xiang, W;Haghikia, A;Akdis, C;Ciccia, F;Bäuerle, T;Sarter, K;Strowig, T;Yissachar, N;Schett, G;Rothhammer, V;Zaiss, M;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

  • All mice then received a single intraperitoneal injection of 200 ng 528 pertussis toxin (List Biological Laboratories, #180) at a concentration in 200 ?l of PBS. Mice 529

Standardizing the skin tape stripping method for sensitization and using it to create a mouse model of peanut allergy

Nesovic, LD;Gonzalez Cruz, PE;Rychener, N;Wilks, LR;Singh Gill, H;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

  • sh tape re-applied each time) ( Fig. 1 B, C) until treated skin achieved the inflamed and shiny appearance akin to shown in Fig. 1 C (7 tape applications). Next, a foam reservoir (Acrysure Next Gen 1/16? PE Foam, Mactac, OH, USA) was applied on the inflamed skin, while taking care to align the reservoir opening (measuring 1 cm by 1 cm) over the inflamed skin ( Fig. 2 A). A 50 µl of peanut extract (PE) (Greer, Laboratories, Inc., NC, USA) +/- cholera toxin (CT) (List Labs, CA, USA), or PBS alone was pipetted into the reservoir ( Fig. 2 B) and covered with an adhesive film (Silk Double Coated 0.5 mil PET, Mactac, OH, USA) ( Fig. 2 C). Another larger adhe

Dosage and organic acid residue of MOG35-55 peptide influences immunopathology and development of BCG induced experimental autoimmune encephalomyelitis (EAE)

Han, X;Wang, Y;Zhang, K;Na, T;Wu, T;Hao, X;Jin, Y;Wang, Y;Wang, H;Meng, S;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

  • Most of the pertussis toxins used in this study were purchased from List Biological 140 Laboratories, Campbell, CA, except for experiments in Figures S1 and Figure S3, in

Pathophysiology of hypereosinophilia-associated heart disease

Sunusi, U;Ziegelmeyer, B;Osuji, I;Medvedovic, M;Todd, H;Abou-Khalil, J;Zimmermann, N;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

  • (Ac-IQAQ ARGQ LMRI EFKK)15 emulsified in complete Freund’s adjuvant (CFA, Sigma-Aldrich) supplemented to 5 mg/ml heat-killed Mycobacterium tuberculosis strain H37Ra (BD Biosciences). On day 0, mice also received 500 ng pertussis toxin intraperitoneally (List Biologicals)16. Pre-challenge and weekly during the protocol venous blood was collected from mice via submandibular puncture. If complete blood counts were being performed,

Immune Checkpoint Inhibition-related Neuroinflammation Disrupts Cognitive Function

Ifejeokwu, OV;Do, A;El Khatib, SM;Ho, NH;Zavala, A;Othy, S;Acharya, MM;

Product: Pertussis Toxin from B. pertussis, Lyophilized (Salt-Free)

  • over the flank region. Additionally, on the day of EAE induction and 48 hours post-induction, 200 ng pertussis toxin (List Biologic Laboratories, Cat. 181) was injected intraperitoneally to each mouse. To induce adoptive-transfer (AT) EAE, WT donor mice were first actively immunized with MOG35-55 peptide and a single dose of pertussis toxin as described above. 11 days later, cells were isolated from the inguinal draining lymph node

Asymptomatic herpes simplex virus brain infection elicits cellular senescence phenotypes in the central nervous system of mice suffering multiple sclerosis-like disease

Duarte, LF;Villalobos, V;Farías, MA;Rangel-Ramírez, MA;González-Madrid, E;Navarro, AJ;Carbone-Schellman, J;Domínguez, A;Alvarez, A;Riedel, CA;Bueno, SM;Kalergis, AM;Cáceres, M;González, PA;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

  • Additionally, mice received two intraperitoneal injections of 350 ng of pertussis toxin (List Biological Laboratories, Inc.) at the time of induction and 48 h later. Daily

GV-971 attenuates the progression of neuromyelitis optica in murine models and reverses alterations in gut microbiota and associated peripheral abnormalities

Yang, X;Zhangyi, Z;Yu, A;Zhou, Q;Xia, A;Qiu, J;Cai, M;Chu, X;Li, L;Feng, Z;Luo, Z;Sun, G;Zhang, J;Geng, M;Chen, S;Xie, Z;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

  • e experimental autoimmune encephalomyelitis (EAE), we administered myelin oligodendrocyte glycoprotein (MOG) (#51716, GL Biochem (Shanghai), Ltd.) and pertussis toxin (PTX) (#180, List Biological) to mice. On day 0, the mice were randomly assigned to different groups (n?=?10). After anesthetizing the mice with isoflurane, we subcutaneously injected an emulsion containing 2?mg/mL MOG35-55 and 4?mg/mL complete Freund's adjuvant (CFA) in equal volumes (10??L each), which had been homogenized for 1?h in a 40?mL brown glass vial. Simultaneously, we intraperitoneally injected 200??L (200?ng) of a diluted PTX solution. After 48?h, th

NK Receptor Signaling Lowers TCR Activation Threshold, Enhancing Selective Recognition of Cancer Cells by TAA-Specific CTLs

Dong, B;Obermajer, N;Tsuji, T;Matsuzaki, J;Bonura, CM;Sander, C;Withers, H;Long, MD;Chavel, C;Olejniczak, SH;Minderman, H;Kirkwood, JM;Edwards, RP;Storkus, WJ;Romero, P;Kalinski, P;

Product: Enterotoxin Type B from Staphylococcus aureus

  • Partner Therapeutics; IL-4, IL-1?, TNF?, and IFN-? were purchased from Miltenyi; IL-6 was purchased from R&D Systems; IFN-? (Intron A- IFN-?-2b) and IL-2 (Proleukin aldesleukin) were purchased from McKesson; PGE2 and poly-I:C were purchased from Sigma-Aldrich; IL-7 and IL12p70 were purchased from Peprotech; Staphylococcus Enterotoxin B (SEB) was purchased from List Labs; Dynabeads Human T-Activator CD3/CD28 was purchased from Gibco; purified Streptavidin was purchased from Biolegend to crosslink biotinylated-antibodies for short-term CTL stimulation. Oxaliplatin and cis-Diammineplatinum(II) Dichloride (Cisplatin) were purchased from Sigma-Aldrich

Polyvinylpyrrolidone-curcumin nanoparticles with immune regulatory and metabolism regulatory effects for the treatment of experimental autoimmune uveitis

Cao, F;Liang, K;Tang, WW;Ni, QY;Ji, ZY;Zha, CK;Wang, YK;Jiang, ZX;Hou, S;Tao, LM;Wang, X;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

  • popolysaccharide (LPS) and complete Freund's adjuvant (CFA) were purchased from Sigma-Aldrich (St. Louis, Missouri, USA). Pertussis toxin (PTX) was purchased from List Biological Labs (USA). Human intercellular retinol-binding protein (IRBP1169-1191, PTARSVGAADGSSWEGVGVVPDV) was purchased from Sangon Bioengineering Technology and Services Co., Ltd. (Shanghai, China). All primary antibodies for immunofluorescenc