Branched chain -ketoacid dehydrogenase kinase 111-130, a T cell epitope that induces both autoimmune myocarditis and hepatitis in A/J mice.

Immunity, Inflammation And Disease

Krishnan, B;Massilamany, C;Basavalingappa, RH;Gangaplara, A;Kang, G;Li, Q;Uzal, FA;Strande, JL;Delhon, GA;Riethoven, JJ;Steffen, D;Reddy, J;

Organ-specific autoimmune diseases are believed to result from immune responses generated against self-antigens specific to each organ. However, when such responses target antigens expressed promiscuously in multiple tissues, then the immune-mediated damage may be wide spread.

PubMed ID: 28597552

Citation

Branched chain -ketoacid dehydrogenase kinase 111-130, a T cell epitope that induces both autoimmune myocarditis and hepatitis in A/J mice.