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Neurology Neuroimmunology & Neuroinflammation

Induction of gut regulatory CD39(+) T cells by teriflunomide protects against EAE

Ochoa-Repraz, J;Colpitts, SL;Kircher, C;Kasper, EJ;Telesford, KM;Begum-Haque, S;Pant, A;Kasper, LH;

To determine whether as an orally delivered treatment, teriflunomide, an inhibitor of the mitochondrial enzyme dihydroorotate dehydrogenase approved to treat relapsing forms of multiple sclerosis, could affect gut-associated lymphoid tissue (GALT) immune responses functionally.

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