Toxoids
Purified neurotoxin is treated with formaldehyde to inactivate the toxin while maintaining epitopes which may be recognized by antibodies. The current lot of BoNT/A toxoid has been prepared using an optimized method for formaldehyde toxoiding. It has been tested for antigenicity and compared with the antigen reactivity of pure neurotoxin. It has been shown that the toxoid resembles the native toxin but is not toxic. Two botulinum toxin toxoids are available from List Labs.
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