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Anti-C. difficile Toxins | Related Citations
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Design, performance, processing, and validation of a pooled CRISPR perturbation screen for bacterial toxins
Nature Protocols
Tian, S;Qin, Y;Wu, Y;Dong, M;
Product: Anti-Clostridium difficile Toxin B (Chicken lgY)
Unbiased forward genetic screens have been extensively employed in biological research to elucidate ....
A rapid multiplex real-time PCR detection of toxigenic Clostridioides difficile directly from fecal samples
3 Biotech
Jia, XX;Wang, YY;Zhang, WZ;Li, WG;Bai, LL;Lu, JX;Ma, CF;Wu, Y;
Product: Anti-Clostridium difficile Toxin A (Chicken lgY)
This study developed a new single-tube multiplex real-time PCR method for detecting toxigenic C. dif....
Identification of TFPI as a receptor reveals recombination-driven receptor switching in Clostridioides difficile toxin B variants
Nature Communications
Tian, S;Xiong, X;Zeng, J;Wang, S;Tremblay, BJ;Chen, P;Chen, B;Liu, M;Chen, P;Sheng, K;Zeve, D;Qi, W;Breault, DT;RodrÃguez, C;Gerhard, R;Jin, R;Doxey, AC;Dong, M;
Product: Anti-Clostridium difficile Toxin B (Chicken lgY)
Toxin B (TcdB) is a major exotoxin responsible for diseases associated with Clostridioides difficile....
TFPI is a colonic crypt receptor for TcdB from hypervirulent clade 2 C.difficile
Cell
Luo, J;Yang, Q;Zhang, X;Zhang, Y;Wan, L;Zhan, X;Zhou, Y;He, L;Li, D;Jin, D;Zhen, Y;Huang, J;Li, Y;Tao, L;
Product: Anti-Clostridium difficile Toxin B (Chicken lgY)
The emergence of hypervirulent clade 2 Clostridioides difficile is associated with severe symptoms a....
Structural basis for CSPG4 as a receptor for TcdB and a therapeutic target in Clostridioides difficile infection
Nature Communications
Chen, P;Zeng, J;Liu, Z;Thaker, H;Wang, S;Tian, S;Zhang, J;Tao, L;Gutierrez, CB;Xing, L;Gerhard, R;Huang, L;Dong, M;Jin, R;
Product: Anti-Clostridium difficile Toxin B (Chicken lgY)
C. difficile is a major cause of antibiotic-associated gastrointestinal infections. Two C. difficile....
Functional analyses of epidemic Clostridioides difficile toxin B variants reveal their divergence in utilizing receptors and inducing pathology
Plos Pathogens
Pan, Z;Zhang, Y;Luo, J;Li, D;Zhou, Y;He, L;Yang, Q;Dong, M;Tao, L;
Product: Anti-Clostridium difficile Toxin B (Chicken lgY)
Clostridioides difficile toxin B (TcdB) is a key virulence factor that causes C. difficile associate....
A Replicating Single-Cycle Adenovirus Vaccine Effective against Clostridium difficile
Vaccines
Matchett, WE;Anguiano-Zarate, S;Malewana, GBR;Mudrick, H;Weldy, M;Evert, C;Khoruts, A;Sadowsky, M;Barry, MA;
Product: Anti-Clostridium difficile Toxin B (Chicken lgY)
Clostridium difficile causes nearly 500,000 infections and nearly 30,000 deaths each year in the U.S....
Sulfated glycosaminoglycans and low-density lipoprotein receptor contribute to Clostridium difficile toxin A entry into cells
Nature Microbiology
Tao, L;Tian, S;Zhang, J;Liu, Z;Robinson-McCarthy, L;Miyashita, SI;Breault, DT;Gerhard, R;Oottamasathien, S;Whelan, SPJ;Dong, M;
Product: Anti-Clostridium difficile Toxin A (Chicken lgY)
Clostridium difficile toxin A (TcdA) is a major exotoxin contributing to disruption of the colonic e....
Frizzled proteins are colonic epithelial receptors for C. difficile toxin B
Nature
Tao, L;Zhang, J;Meraner, P;Tovaglieri, A;Wu, X;Gerhard, R;Zhang, X;Stallcup, WB;Miao, J;He, X;Hurdle, JG;Breault, DT;Brass, AL;Dong, M;
Product: Anti-Clostridium difficile Toxin B (Chicken lgY)
Clostridium difficile toxin B (TcdB) is a critical virulence factor that causes diseases associated ....
Toll-like receptor 5-dependent immunogenicity and protective efficacy of a recombinant fusion protein vaccine containing the nontoxic domains of Clostridium difficile toxins A and B and Salmonella enterica serovar typhimurium flagellin in a mouse model of
Infection And Immunity
Ghose, C;Verhagen, JM;Chen, X;Yu, J;Huang, Y;Chenesseau, O;Kelly, CP;Ho, DD;
Product: Anti-Toxin A from Clostridium difficile (Goat)
Clostridium difficile is a spore-forming bacillus that produces toxin-mediated enteric disease. C. d....
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