Toxoids of both Clostridium difficile Toxin A and Toxin B are prepared from purified toxin by formaldehyde inactivation. All preparations are tested for cytotoxicity, and results are in a C of A that is provided with every shipment.
Product #153 Toxin A Toxoid from C. difficile is provided lyophilized in a histidine buffer.
Product #154 Toxin B Toxoid from C. difficile is provided lyophilized in a histidine buffer.
By: Rachel Berlin, Marketing Manager Microbiome research is uncovering the enormous potential for developing drugs, such a live biotherapeutic products, from the microbiome. This burgeoning field is the future of medicine. List Labs is excited and proud to support microbiome research by providing reagents to scientists studying the human microbiome. Below is a list of microbiome […]
By: Mary N. Wessling, Ph.D. ELS List Biological Laboratories’ (List Labs) catalog of products is related to furthering research in human health and preventing disease, most commonly as the starting materials for vaccine research & development or production around the world. Vaccines are mainly identified for their capacity to prevent diseases that the body’s innate defensive […]
By: Rachel Berlin, Marketing Manager The List Labs website hosts a library of scientific article abstracts related to the research performed using our products called the Citations Page. Visitors can search this library to learn how others have used List Labs’ reagents in their research. This valuable resource is updated monthly with new articles from a wide variety […]
By: Mary N. Wessling, Ph.D. ELS List Biological Laboratories, Inc.’s products are being used to confront one of the most pressing problems in health care today: stopping the worldwide spread of illness caused by Clostridium difficile (CD, C Difficile Toxin), a gram-positive, spore-forming anaerobic bacillus. The spores are highly resistant to adverse environmental conditions and are […]
By: Suzanne Canada, Ph.D. Tanager Medical Writing Concerns over outbreaks of potentially serious childhood diseases are in the news again in California with an increase in whooping cough infections in 2014, caused by the pathogen Bordetella pertussis, and a measles outbreak in December 2014 to February 2015. Since outbreaks and epidemics may be infrequent, many […]
By: Suzanne Canada, Ph.D. Tanager Medical Writing While you go about your day, you are surrounded by micro-organisms. Although most of us spend a lot of time washing up and trying not to think about the propensity of creatures that share our personal space, scientists have been studying them. Due to their great progress, we […]
By: Karen Crawford, Ph.D. President, List Biological Laboratories, Inc. Many bacterial products are potent immune system activators, helping our bodies identify and defend against microbial invasions. The innate immune system or non-specific immune system is found in animals as well as in plants, fungi and insects and is employed when pathogens break through the […]
What is Clostridium Difficile? Clostridium difficile is the causative agent of antibiotic-associated diarrhea and pseudomembranous colitis. It produces two major exotoxins, Toxin A and Toxin B; however, about 10% of strains isolated from patients with colitis also contain genes, coding for a unique ADP-ribosylating toxin, CDT Binary Toxin. Additionally, Clostridium difficile produces and secretes a glutamate […]
What Are Toxin Neutralization Assays & How Do They Work? For clinical detection or vaccine testing, it is hard to beat a toxin neutralization assay. Toxin neutralization assays (TNA) assess the ability of antibodies to protect cells in culture from the cytotoxic affect of the specific toxins. Interestingly, these assays may be used for sensitive […]
By: Karen Crawford, Ph.D. President, List Biological Laboratories, Inc. You hear about Clostridium difficile at your doctor’s office and in news articles, but what does it mean and how does it affect the world around us? C. Difficile Statisitcs C. Difficile Mortality Rates: Complications from C. difficile infection (CDI) have become an increasing patient safety concern […]