Purified tetanus toxin is formaldehyde treated to form toxoid. Starting with purified tetanus toxin, this toxoid does not contain crosslinked culture components or other contaminates characteristic of toxoid derived from culture filtrates. This is a purified product, suitable for dialysis into a reaction buffer and conjugation of antigens for antibody production. Toxoid is tested for purity, toxicity, immunoprecipitation and endotoxin contamination.
By: Mary N. Wessling, Ph.D. ELS In this blog we will unravel the terminology describing bacterial toxins. In general, there are at least three ways that bacterial toxins are described in the literature: by their biological designation—the genus and/or species from which they come by the origin of the toxin, either as innate to the […]
By: Mary N. Wessling, Ph.D. ELS List Biological Laboratories’ (List Labs) catalog of products is related to furthering research in human health and preventing disease, most commonly as the starting materials for vaccine research & development or production around the world. Vaccines are mainly identified for their capacity to prevent diseases that the body’s innate defensive […]
By: Rachel Berlin, Marketing Manager List Labs is proud to be exhibiting at ASM Biothreats February 12-14th. The conference will be held in Baltimore, Maryland at the Hilton Hotel. Thought leaders in academia, industry and government will gather to present and discuss the latest developments in the emerging field of biothreats. This year’s conference has […]
By: Mary N. Wessling, Ph.D. ELS Tetanus Toxin’s Use as a Protein Carrier and Antigen Tetanus toxin (TT) is the major virulence factor of the Gram-positive bacterium Clostridium tetani. Infection with this bacterium in unvaccinated persons produces muscle spasms by binding to nerve endings and moving throughout the nervous system in a specific way. Eventually, […]
By: Md. Elias, Ph.D, Senior Scientist List Labs is one of the leading manufacturers of high quality adjuvants from bacterial sources. Our highly purified adjuvants for research and development are Tetanus Toxoid (Product #191), Cholera Toxin B Subunit (Product #104), Diphtheria Toxin CRM197 Mutant (Product #149), Adenylate Cyclase Mutant, Cya-AC– (Product #198L), Pertusis Toxin Mutant (Product #184), […]
By: Dom C. Ouano, Marketing Coordinator Since List Labs introduced products in the Tetanus Toxin family more than 25 years ago, interest and knowledge in this field has multiplied. Tetanus Toxin C fragment, the non-toxic C-terminal domain of the heavy chain, is retrogradely transported to the central nervous system and is useful as a neuronal […]
By: Suzanne Canada, Ph.D. Tanager Medical Writing Concerns over outbreaks of potentially serious childhood diseases are in the news again in California with an increase in whooping cough infections in 2014, caused by the pathogen Bordetella pertussis, and a measles outbreak in December 2014 to February 2015. Since outbreaks and epidemics may be infrequent, many […]