List Labs Bacterial Toxin & Vaccine Research Blog

Anthrax toxin research takes several directions in 2014

January 5, 2015

By: List Labs

By: Suzanne Canada, Ph.D. Tanager Medical Writing Three anthrax toxin components—Protective antigen (PA), edema factor (EF) and lethal factor (LF) are available for research purposes from LIST Biological Laboratories, separately at a high level of purification. At least two out of three of these components are necessary to enter a mammalian cell and exert […]

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How to kick start the immune system

December 15, 2014

By: douano@listlabs.com

By: Karen Crawford, Ph.D. President, List Biological Laboratories, Inc. Many bacterial products are potent immune system activators, helping our bodies identify and defend against microbial invasions. The innate immune system or non-specific immune system is found in animals as well as in plants, fungi and insects and is employed when pathogens break through the […]

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How the Body Defends Against Environmental Toxins

December 8, 2014

By: List Labs

By: Suzanne Canada, Ph.D. Tanager Medical Writing An ongoing barrage of information and mis-information has been dispersed through various media about the dangers of toxins in our environment. Although everyone agrees that you certainly should avoid ingesting, inhaling, or absorbing toxins into your body; your body has natural ways of removing toxins. Some new […]

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Bacterial toxins for vaccine research and design

October 21, 2014

By: List Labs

By: Suzanne Canada, Ph.D. Tanager Medical Writing Vaccines have been used to help control diseases for more than 200 years and are the common practice for children and adults. Childhood vaccination has substantially reduced the morbidity and mortality from infectious diseases in much of the developed world, and influenza vaccinations have reduced the impact […]

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Bordetella Pertussis uses Adenylate Cyclase Toxin-Hemolysin to fight off immune cells

September 30, 2014

By: douano@listlabs.com

Adenylate cyclase toxin-hemolysin (ACT, AC-Hly, or CyaA) is an important virulence factor for Bordetella pertussis. Adenylate cyclase toxin is a large (178 kDa), 1,706-residue-long, toxin consisting of an amino-terminal adenylate cyclase (AC) domain of 400 residues and a repeat toxin (RTX) moiety of 1,306 residues. Sequences within the RTX domain are responsible for target binding, pore-formation […]

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Staphylococcus Enterotoxin B Stimulates T-Cell Proliferation

July 28, 2014

By: List Labs

By: Suzanne Canada, Ph.D. Tanager Medical Writing The world of microbial pathology is often understood as a system of various organisms who are trying to survive by using plants or animals as “hosts”. The dynamics of these systems can described the pathogen as trying to establish a living space for itself, while the “host” […]

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