List Labs Bacterial Toxin & Vaccine Research Blog

Bordetella Pertussis uses Adenylate Cyclase Toxin-Hemolysin to fight off immune cells

September 30, 2014

By: douano@listlabs.com

Adenylate cyclase toxin-hemolysin (ACT, AC-Hly, or CyaA) is an important virulence factor for Bordetella pertussis. Adenylate cyclase toxin is a large (178 kDa), 1,706-residue-long, toxin consisting of an amino-terminal adenylate cyclase (AC) domain of 400 residues and a repeat toxin (RTX) moiety of 1,306 residues. Sequences within the RTX domain are responsible for target binding, pore-formation […]

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Staphylococcus Enterotoxin B Stimulates T-Cell Proliferation

July 28, 2014

By: List Labs

By: Suzanne Canada, Ph.D. Tanager Medical Writing The world of microbial pathology is often understood as a system of various organisms who are trying to survive by using plants or animals as “hosts”. The dynamics of these systems can described the pathogen as trying to establish a living space for itself, while the “host” […]

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New C. difficile product and improvements

July 21, 2014

By: List Labs

List Biological Laboratories, Inc. is pleased to announce a key addition to our Clostridium difficile Toxin A and Toxin B product line. Our new product, 155L is a liquid formulation of Toxin B. This product allows for the highest activity level of any of our C.difficile offerings and the most stability. It already shows stability […]

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Volume discounts and bulk orders save you more

July 17, 2014

By: dpinkston@listlabs.com

Volume Discounts on Toxins and Reagents List Laboratories has been in business since 1978. We’ve been providing our customers with quality toxins and custom manufacturing services for decades. We want to make it easier for everyone within your company to purchase and receive the best value for those purchases. We have recently begun a […]

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Lipopolysaccharide (LPS): Key Role in Immune Response and Research

June 17, 2014

By: dpinkston@listlabs.com

What is Lipopolysaccharide (LPS) and How Does it Function? Lipopolysaccharide (LPS), a component of the outer membrane of Gram-negative bacteria, is a potent stimulator of the vertebrate innate immune system. This innate immune system, mediated by macrophages and dendritic cells, generates a rapid response to infectious agents. Structural patterns common to diverse LPS molecules are […]

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New C. difficile proteins improve discovery and detection

May 14, 2014

By: dpinkston@listlabs.com

What is Clostridium Difficile? Clostridium difficile is the causative agent of antibiotic-associated diarrhea and pseudomembranous colitis. It produces two major exotoxins, Toxin A and Toxin B; however, about 10% of strains isolated from patients with colitis also contain genes, coding for a unique ADP-ribosylating toxin, CDT Binary Toxin. Additionally, Clostridium difficile produces and secretes a glutamate […]

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