Citations

Bacterial Toxin Research Citations

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5030 citations found

Aromatic substances in wheat malt inducing antisecretory factor and resistance to diarrhoea

Johansson, E;Lange, S;Lnnroth, I;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

Activation of constitutive androstane receptor inhibits intestinal CFTR-mediated chloride transport

Kittayaruksakul, S;Sawasvirojwong, S;Noitem, R;Pongkorpsakol, P;Muanprasat, C;Chatsudthipong, V;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

  • Chemicals and reagents:

    Cholera toxin was purchased from List Biological Laboratories, Inc. (Campbell, CA, USA). …

    Results – 

    Effect of CAR activation on cholera toxin (CT)-induced Cl secretion in T84 cells:

    As activation of CFTR-dependent Cl secretion is involved in the pathogenesis of secretory diarrhea especially cholera [23], the therapeutic potential of CAR agonist on cholera toxin (CT)-induced Cl secretion by T84 cell monolayers was investigated using short-circuit current analysis. Snapwell inserts containing confluent T84 cells were treated with 1M CITCO for 24h followed by mounting in an Ussing chamber. Then, 1g/ml of CT was added into apical Krebs buffer to stimulate Clsecretion. As demonstrated in Fig. 8, CT-induced Cl secretion in T84 cells was significantly reduced by CITCO (78.66.0% of control).

    Product #100B – Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

Impact of clinical pharmacist engagement in ward teams on the number of drug-related readmissions among older patients with dementia or cognitive impairment: An economic evaluation

Sjlander, M;Lindholm, L;Pfister, B;Jonsson, J;Schneede, J;Lvheim, H;Gustafsson, M;

Product: Anti-Cholera Toxin B Subunit (Goat)

Akt-1 and Akt-2 Differentially Regulate the Development of Experimental Autoimmune Encephalomyelitis by Controlling Proliferation of Thymus-Derived Regulatory T Cells

Ouyang, S;Zeng, Q;Tang, N;Guo, H;Tang, R;Yin, W;Wang, A;Tang, H;Zhou, J;Xie, H;Langdon, WY;Yang, H;Zhang, J;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae

  • Mice:

    C57BL/6J (stock #000664), MHCIIfl/fl (stock #013181) [89], and Arg1fl/fl (stock #008817) [90] mice were purchased from the Jackson Laboratory (JAX). CCR2-/- mice (JAX stock #004999) [34] were generously provided by Dr. E Pamer (MSKCC). Rosa26flSTOP-tdRFP mice [36] were generously provided by Dr. J. Sun (MSKCC) [91]. The dblGATA mice [50] on a C57BL/6 background were generously provided by Dr. H. Rosenberg (NIH). Vav1-Cre mice (JAX stock #008610) [92] were generously provided by Dr. F Geissmann (MSKCC). RAG2-/-c-/- mice (stock #4111) [9394] were purchased from Taconic. CD45.1+ mice (stock #564) were purchased from Charles River Laboratories. The CCR2-DTR depleter mice and CCR2-GFP reporter mice were generated as previously described [595]. All mouse strains were bred and housed in the Memorial Sloan Kettering Cancer Centers (MSKCC) Research Animal Resource Center under specific pathogen-free conditions. Mice on the RAG-/-c-/- background were maintained on amoxicillin- and Vitamin E-containing chow. To ablate monocytes, CCR2-DTR or CCR2-DTR RAG-/-c-/- mice and their control littermates were injected intraperitoneally with 200 ng (10 ng/g body weight) of diphtheria toxin (List Biological Laboratories) every other day for three doses, starting the day before infection (Fig 1B), unless otherwise noted. All experiments were conducted using male and female mice at age 68 weeks with sex- and age-matched mice in experimental and control groups. Experiments with CCR2-DTR, CCR2-DTR RAG-/-c-/-, CCR2-Cre and Vav1-Cre mice used littermate control mice that were weaned from the same litters and co-housed.

Proteomic analysis reveals a protective role of specific macrophage subsets in liver repair

Yang, W;Zhao, X;Tao, Y;Wu, Y;He, F;Tang, L;

Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae

Laquinimod, a prototypic quinoline-3-carboxamide and aryl hydrocarbon receptor agonist, utilizes a CD155-mediated natural killer/dendritic cell interaction to suppress CNS autoimmunity

Ott, M;Avendao-Guzmn, E;Ullrich, E;Dreyer, C;Strauss, J;Harden, M;Schn, M;Schn, MP;Bernhardt, G;Stadelmann, C;Wegner, C;Brck, W;Nessler, S;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Lateral parabrachial neurons innervate orexin neurons projecting to brainstem arousal areas in the rat

Arima, Y;Yokota, S;Fujitani, M;

Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

  • Combined anterograde tracing and retrograde tracing:

    Ipsilateral injections of BDA (Thermo Fisher Scientific, Waltham, MA, USA) into the LPB and CTb (List Biological Labs, Campbell, CA, USA) into the VTA (4 out of 10 rats received a successful injection), DR (4 out of 10 rats received a successful injection), PPT (4 out of 14 rats received a successful injection), LDT (4 out of 14 rats received a successful injection) or LC (4 out of 12 rats received a successful injection) were made stereotaxically by iontophoresis. In each rat, a single injection of CTb into these regions was made using a glass micropipette filled with 0.5% solution of CTb dissolved in 0.05M phosphate buffer (PB; pH 6.0). The driving current (56mA, 200ms, 2Hz) was delivered for 30-40min. After CTb injection, a single injection of BDA was made into the LPB via a glass micropipette filled with a 10% solution of BDA dissolved in 0.01M PB (pH 7.3). The driving current (56mA, 200ms, 2Hz) was delivered for 4060min.

    Product #104 – Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

Evaluation of a non-canonical Cys40-Cys55 disulfide linkage for stabilization of single-domain antibodies

Kim, DY;Kandalaft, H;Hussack, G;Raphael, S;Ding, W;Kelly, JF;Henry, KA;Tanha, J;

Product: Toxin A from Clostridium difficile

Yersinia pestis Pla protein thwarts T cell defense against plague

Smiley, ST;Szaba, FM;Kummer, LW;Duso, DK;Lin, JS;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

  • Immunization and challenge.

    Mice were lightly anesthetized by the use of isoflurane for intranasal administration. For immunization with D27-pLpxL, mice were primed with intranasal inoculation of 2 × 106 CFU D27-pLpxL in 30 μl saline solution, boosted with the same dose of D27-pLpxL 30 days later, and rested for 60 days before challenge. For peptide immunizations, mice were inoculated intranasally with a 15-μl solution containing 1 μg cholera toxin (CT; List Biological Laboratory, Campbell, CA) as the adjuvant
    and …

    Product #100B – Cholera Toxin (AZIDE-FREE) from Vibrio cholerae