Citations

Bacterial Toxin Research Citations

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5030 total record number 58 records this year

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5030 citations found

Interactions of high-affinity cationic blockers with the translocation pores of B. anthracis, C. botulinum, and C. perfringens binary toxins

Bezrukov, SM;Liu, X;Karginov, VA;Wein, AN;Leppla, SH;Popoff, MR;Barth, H;Nestorovich, EM;

Product: Anthrax Protective Antigen, Activated (PA 63) from B. anthracis

  • Reagents:

    PA63 was purchased from List Biological Laboratories (Campbell, CA). …

    Channel reconstitution into planar lipid bilayers:

    … For multichannel experiments, we applied 12 l of 0.2 mg ml1 stock PA63. Under this protocol, the channel insertions were always directional. The applied potential was defined as positive if it was higher on the side of protein addition.

Dependence of regenerated sensory axons on continuous neurotrophin-3 delivery

Hou, S;Nicholson, L;van Niekerk, E;Motsch, M;Blesch, A;

Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

CD28 promotes CD4+ T cell clonal expansion during infection independently of its YMNM and PYAP motifs

Pagn, AJ;Pepper, M;Chu, HH;Green, JM;Jenkins, MK;

Product: Unspecified List Labs LPS

  • RelA translocation assay:

    OT-II CD90.1+CD4+ T cells were isolated from spleen and lymph nodes with a CD4+ T cell isolation kit (Miltenyi Biotec), and 0.51 3 106 cells were adoptively transferred into CD90.2+ wild-type recipients. The next day, recipient mice were injected i.v. with 5 mg of Escherichia coli LPS (List Biological Laboratories) diluted in PBS, and then a day later, some mice were injected i.v. with 100 mg of chicken OVA peptide 323339 (Invitrogen) diluted in PBS. …

    Author did not specify which List Labs LPS product was utilized in their research.  List Labs provides the following LPS products:  https://listlabs.com/product-information/lipopolysaccharides/

Ingested (oral) neuropeptide Y inhibits EAE

Brod, SA;Bauer, VL;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

CD5-dependent CK2 activation pathway regulates threshold for T cell anergy.

Sestero, CM;McGuire, DJ;De Sarno, P;Brantley, EC;Soldevila, G;Axtell, RC;Raman, C;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Myelin basic protein-specific TCR/HLA-DRB5*01:01 transgenic mice support the etiologic role of DRB5*01:01 in multiple sclerosis

Quandt, JA;Huh, J;Baig, M;Yao, K;Ito, N;Bryant, M;Kawamura, K;Pinilla, C;McFarland, HF;Martin, R;Ito, K;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Phenethyl Isothiocyanate Inhibits Ovalbumin-induced Inducible Nitric Oxide Synthase Expression

Shin, H;Youn, H;

Product: Unspecified List Labs LPS

Intravascular neutrophil extracellular traps capture bacteria from the bloodstream during sepsis

McDonald, B;Urrutia, R;Yipp, BG;Jenne, CN;Kubes, P;

Product: LPS from Escherichia coli O111:B4

  • Experimental Protocols:

    Mice were treated with an intraperitoneal injection of 1 mg/kg purified LPS from E. coli 0111:B4 (List Biologicals) 4 hr prior to intravital microscopy. The dose of LPS used in this study was sufficiently low that animals survived anesthesia and hepatic perfusion was not severely diminished. The purity of the commercial LPS was confirmed by inoculation into TLR4 knockout (TLR4/) animals and observation of no measurable response in any of the parameters reported in this study (data not shown). For platelet depletion experiments, mice were injected i.p. with 50 l anti-mouse thrombocyte serum or 50 l control serum (adsorbed normal rabbit serum) 24 hr prior to LPS administration or E. coli infection. For neutrophil depletion experiments, mice were injected i.p. with 200 g anti-Gr-1 antibody or 200 g rat IgG control antibody 24 hr prior to LPS administration. Platelet and neutrophil depletion were confirmed with SD-IVM (see Figure 2). In some experiments, mice were treated with 2000 U DNase intravenously at various time points after infection with E. coli (noted in the figure legends). 

Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae

  • Mouse Treatments and Immunizations:

    For immunization with OVA in complete Freunds adjuvant (OVA/CFA), OVA was emulsified in CFA at final concentration of 1 mg/ml OVA, and mice received hind footpad injection of 20 l of OVA/CFA as described (Webster et al., 2006).

    Foxp3-DTR mice express simian diphtheria toxin (DT) receptor that allows for depletion of Foxp3+ regulatory T cells upon DT administration (Kim et al., 2007; Chinen et al., 2010). For regulatory T cell depletion, wild-type control or Foxp3-DTR mice were injected intraperitoneally with 1.5 g of DTList Biological Laboratory, Campbell, CA, USA) on days 0, 1, 4, and 7 and examined on day 8. CD4+, CD25+, Foxp3+ regulatory T cells in lymph nodes were depleted by at least 12-fold by day 8.