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Investigations of Thiosemicarbazides as Botulinum Toxin Active-Site Inhibitors: Enzyme, Cellular, and Rodent Intoxication Studies
ACS Infectious Diseases
Patel, EN;Lin, L;Park, H;Sneller, MM;Eubanks, LM;Tepp, WH;Pellet, S;Janda, KD;
Product: SNAPtide® Peptide Substrate flP6(DABCYL/5-IAF) for C. botulinum Type A Neurotoxin
Botulinum neurotoxin type A (BoNT/A) is an exceptionally potent neurotoxin of great therapeutic valu....
A Preclinical Study Comparing the Activity and Potency of OnabotulinumtoxinA and PrabotulinumtoxinA
Clinical, Cosmetic And Investigational Dermatology
Rupp, DC;Canty, D;Rhéaume, C;Sondergaard, B;Niño, C;Broide, RS;Brideau-Andersen, AD;
Product: SNAPtide® Peptide Substrate (o-Abz/Dnp) for C. botulinum Type A Neurotoxin
The goal of this study was to compare the unit-to-unit biological activity of the vacuum-dried formu....
Transformation of a Metal Chelate into a Catch and Anchor Inhibitor of Botulinum A Protease
International Journal Of Molecular Sciences
Lin, L;Patel, E;Nielsen, A;Turner, L;Tepp, W;Nguyen, K;Pellett, S;Janda, K;
Product: SNAPtide® Peptide Substrate (FITC/DABCYL) for C. botulinum Type A Neurotoxin
Targeting the botulinum neurotoxin light chain (LC) metalloprotease using small-molecule metal chela....
Investigation of Salicylanilides as Botulinum Toxin Antagonists
ACS Infectious Diseases
Patel, EN;Lin, L;Sneller, MM;Eubanks, LM;Tepp, WH;Pellett, S;Janda, KD;
Product: SNAPtide® Peptide Substrate flP6(DABCYL/5-IAF) for C. botulinum Type A Neurotoxin
Botulinum neurotoxin serotype A (BoNT/A) is recognized by the Centers for Disease Control and Preven....
Product: SNAPtide® Peptide Substrate (o-Abz/Dnp) for C. botulinum Type A Neurotoxin
Botulinum neurotoxin A (BoNT/A), which causes botulism, is the most potent toxin known. Intoxication....
Botulinum Toxin as an Ultrasensitive Reporter for Bacterial and SARS-CoV-2 Nucleic Acid Diagnostics
Biosensors And Bioelectronics
Song, F;Shen, Y;Wei, Y;Yang, C;Ge, X;Wang, A;Li, C;Wan, Y;Li, J;
Product: SNAPtide® Peptide Substrate (FITC/DABCYL) for C. botulinum Type A Neurotoxin
The rapid identification of pathogenic microorganisms plays a crucial role in the timely diagnosis a....
Wrinkle in Time: Development of Botulinum Neurotoxin Light Chain a Inhibitors through Structure Activity Relationship Studies
Thesis
Ku, A;
Product: SNAPtide® Peptide Substrate (o-Abz/Dnp) for C. botulinum Type A Neurotoxin
The botulinum neurotoxin serotype A (BoNT/A) is the deadliest toxin known to man with a lethal dose ....
Catch and Anchor Approach To Combat Both Toxicity and Longevity of Botulinum Toxin A
Journal of Medicinal Chemistry
Lin, L;Olson, ME;Sugane, T;Turner, LD;Tararina, MA;Nielsen, AL;Kurbanov, EK;Pellett, S;Johnson, EA;Cohen, SM;Allen, KN;Janda, KD;
Product: SNAPtide® Peptide Substrate flP6(DABCYL/5-IAF) for C. botulinum Type A Neurotoxin
Botulinum neurotoxins have remarkable persistence (?weeks to months in cells), outlasting the small-....
OnabotulinumtoxinA Displays Greater Biological Activity Compared to IncobotulinumtoxinA, Demonstrating Non-Interchangeability in Both In Vitro and In Vivo Assays
Toxins
Rupp, D;Nicholson, G;Canty, D;Wang, J;Rhaume, C;Le, L;Steward, LE;Washburn, M;Jacky, BP;Broide, RS;Philipp-Dormston, WG;Brin, MF;Brideau-Andersen, A;
Product: SNAPtide® Peptide Substrate (o-Abz/Dnp) for C. botulinum Type A Neurotoxin
Differences in botulinum neurotoxin manufacturing, formulation, and potency evaluation can impact do....
Optimization of a FRET Assay for Evaluating the Biological Activity of Anthrax Lethal Factor Inhibitors
Pointloma.Whdl.Org
Veenbaas, SD;Rouffet, MJ;
Product: MAPKKide® Peptide Substrate (o-Abz/Dnp) for Anthrax Lethal Factor
Anthrax is a deadly infection caused by spores of the gram-positive bacterium Bacillus anthracis. Pa....
Design and use of a novel substrate for simple, rapid, and specific early detection of anthrax infection
Plos One
Suryadi, K;Shine, N;
Product: MAPKKide® Plus (AMC) Specific Substrate for Anthrax Lethal Factor
Bacillus anthracis is a major biological warfare threat. The inhalation form of infection can kill q....
An investigation of the pH dependence of copper-substituted anthrax lethal factor and its mechanistic implications
Journal Of Inorganic Biochemistry
Young, CJ;Richard, K;Beruar, A;Lo, SY;Siemann, S;
Product: MAPKKide® Peptide Substrate (o-Abz/Dnp) for Anthrax Lethal Factor
Anthrax lethal factor (LF) is a zinc-dependent endopeptidase involved in the cleavage of proteins cr....
Differential endopeptidase activity of different forms of type A botulinum neurotoxin: A unique relationship between the size of the substrate and activity of the enzyme
Toxicon : Official Journal Of The International Society On Toxinology
Ambrin, G;Kumar, R;Singh, BR;
Product: SNAPtide® Peptide Substrate (FITC/DABCYL) for C. botulinum Type A Neurotoxin
Botulinum neurotoxins (BoNTs; serotypes A-G) are metalloproteases, which cleave and inactivate cellu....
High Yield Preparation of Functionally Active Catalytic-Translocation Domain Module of Botulinum Neurotoxin Type A That Exhibits Uniquely Different Enzyme Kinetics
The Protein Journal
Dhaliwal, HK;Thiruvanakarasu, N;Kumar, R;Patel, K;Ambrin, G;Cai, S;Singh, BR;
Product: SNAPtide® Peptide Substrate (o-Abz/Dnp) for C. botulinum Type A Neurotoxin
Botulinum neurotoxins (BoNTs) are the most toxic proteins known to cause flaccid muscle paralysis as....
Newly Designed Quinolinol Inhibitors Mitigate the Effects of Botulinum Neurotoxin A in Enzymatic, Cell-Based, and ex Vivo Assays
Journal of Medicinal Chemistry
Bremer, PT;Adler, M;Phung, CH;Singh, AK;Janda, KD;
Product: SNAPtide® Peptide Substrate (FITC/DABCYL) for C. botulinum Type A Neurotoxin
Botulinum neurotoxin A (BoNT/A) is one of the most deadly toxins and is the etiological agent of the....
Cross-inhibition of pathogenic agents and the host proteins they exploit
Scientific Reports
Zilbermintz, L;Leonardi, W;Tran, SH;Zozaya, J;Mathew-Joseph, A;Liem, S;Levitin, A;Martchenko, M;
Product: MAPKKide® Peptide Substrate (DABCYL/FITC) for Anthrax Lethal Factor
The major limitations of pathogen-directed therapies are the emergence of drug-resistance and their ....
Bithionol blocks pathogenicity of bacterial toxins, ricin, and Zika virus
Scientific Reports
Leonardi, W;Zilbermintz, L;Cheng, LW;Zozaya, J;Tran, SH;Elliott, JH;Polukhina, K;Manasherob, R;Li, A;Chi, X;Gharaibeh, D;Kenny, T;Zamani, R;Soloveva, V;Haddow, AD;Nasar, F;Bavari, S;Bassik, MC;Cohen, SN;Levitin, A;Martchenko, M;
Product: SNAPtide® Peptide Substrate (FITC/DABCYL) for C. botulinum Type A Neurotoxin
Diverse pathogenic agents often utilize overlapping host networks, and hub proteins within these net....
High-Throughput Screening Uncovers Novel Botulinum Neurotoxin Inhibitor Chemotypes
ACS Combinatorial Science
Bompiani, KM;Cagli, D;Krutein, MC;Benoni, G;Hrones, M;Lairson, LL;Bian, H;Smith, GR;Dickerson, TJ;
Product: SNAPtide® Peptide Substrate (FITC/DABCYL) for C. botulinum Type A Neurotoxin
Botulism is caused by potent and specific bacterial neurotoxins that infect host neurons and block n....
Identification of small molecule inhibitors of botulinum neurotoxin serotype E via footprint similarity.
Bioorganic & Medicinal Chemistry
Zhou, Y;McGillick, BE;Teng, YG;Haranahalli, K;Ojima, I;Swaminathan, S;Rizzo, RC;
Product: SNAP Etide® Peptide Substrate (o-Abz/Dnp) for C. botulinum Type E Neurotoxin
Botulinum neurotoxins (BoNT) are among the most poisonous substances known, and of the 7 serotypes (....
Substrate For Specific and Quantitative Detection of Anthrax Lethal Factor in Plasma
List Labs POSTER - For ASM Biodefense 2016
Shine, N., Suryadi, K.
Product: MAPKKide® Plus (AMC) Specific Substrate for Anthrax Lethal Factor
Bacillus anthracis is regarded as a major biological warfare threat. The inhalation form of Bacillus....
Investigation of the substrate recognition mechanisms of botulinum neurotoxin and its application in detection and therapy development
Thesis
Guo, J;
Product: VAMPtide® Peptide Substrate (o-Abz/Dnp) Substrate for C. botulinum Type B Neurotoxin
Removal of Botulinum Neurotoxin a Surrogate from Reusable Medical Device Surfaces
Applied Biosafety
Lucas, AD;Di Prima, MA;Hitchins, VM;
Product: SNAPtide® Peptide Substrate (FITC/DABCYL) for C. botulinum Type A Neurotoxin
Botulinum neurotoxin A (BoNT/A) is on the national select agent registry and can be an extremely pot....
Computer-aided identification, synthesis, and biological evaluation of novel inhibitors for botulinum neurotoxin serotype A.
Bioorganic & Medicinal Chemistry
Teng, YH;Berger, WT;Nesbitt, NM;Kumar, K;Balius, TE;Rizzo, RC;Tonge, PJ;Ojima, I;Swaminathan, S;
Product: SNAP-25 Recombinant Protein Substrate for C. botulinum Types A and E Neurotoxin
Botulinum neurotoxins (BoNTs) are among the most potent biological toxin known to humans, and are cl....
Identification of agents effective against multiple toxins and viruses by host-oriented cell targeting
Scientific Reports
Zilbermintz, L;Leonardi, W;Jeong, SY;Sjodt, M;McComb, R;Ho, CL;Retterer, C;Gharaibeh, D;Zamani, R;Soloveva, V;Bavari, S;Levitin, A;West, J;Bradley, KA;Clubb, RT;Cohen, SN;Gupta, V;Martchenko, M;
Product: MAPKKide® Peptide Substrate (DABCYL/FITC) for Anthrax Lethal Factor
A longstanding and still-increasing threat to the effective treatment of infectious diseases is resi....
A simple, rapid and sensitive FRET assay for botulinum neurotoxin serotype B detection
PLoS ONE
Guo, J;Xu, C;Li, X;Chen, S;
Product: SNAPtide® Peptide Substrate (o-Abz/Dnp) for C. botulinum Type A Neurotoxin
Botulinum neurotoxins (BoNTs), the most potent naturally-occurring neurotoxins known to humans, comp....
High-throughput screening technologies for botulinum neurotoxins
Current Topics In Medicinal Chemistry
Bompiani, KM;Dickerson, TJ;
Product: SNAPtide® Peptide Substrate (FITC/DABCYL) for C. botulinum Type A Neurotoxin
Botulinum neurotoxins (BoNTs) are a class of bacterial neurotoxins that are the most potent toxic co....
High metal substitution tolerance of anthrax lethal factor and characterization of its active copper-substituted analogue
Journal of Inorganic Biochemistry
Lo, SY;Sbel, CE;Webb, MI;Walsby, CJ;Siemann, S;
Product: MAPKKide® Peptide Substrate (o-Abz/Dnp) for Anthrax Lethal Factor
Anthrax lethal factor (LF) is a zinc-dependent metalloendopeptidase and a member of the gluzincin fa....
Benzoquinones as inhibitors of botulinum neurotoxin serotype A
Bioorganic & Medicinal Chemistry
Bremer, PT;Hixon, MS;Janda, KD;
Product: SNAPtide® Peptide Substrate (FITC/DABCYL) for C. botulinum Type A Neurotoxin
Although botulinum neurotoxin serotype A (BoNT/A) is known for its use in cosmetics, it causes a pot....
Differential role of molten globule and protein folding in distinguishing unique features of botulinum neurotoxin
Biochimica et Biophysica Acta (BBA) - Proteins And Proteomics
Kumar, R;Kukreja, RV;Cai, S;Singh, BR;
Product: VAMPtide® Peptide Substrate (o-Abz/Dnp) Substrate for C. botulinum Type B Neurotoxin
Botulinum neurotoxins (BoNTs) are proteins of great interest not only because of their extreme toxic....
Botulinum neurotoxin: unique folding of enzyme domain of the most-poisonous poison
Journal Of Biomolecular Structure And Dynamics
Kumar, R;Kukreja, RV;Li, L;Zhmurov, A;Kononova, O;Cai, S;Ahmed, SA;Barsegov, V;Singh, BR;
Product: SNAPtide® Peptide Substrate (FITC/DABCYL) for C. botulinum Type A Neurotoxin
Botulinum neurotoxin (BoNT), the most toxic substance known to mankind, is the first example of the ....
Identification of clinically viable quinolinol inhibitors of botulinum neurotoxin A light chain
Journal of Medicinal Chemistry
Cagli, D;Krutein, MC;Bompiani, KM;Barlow, DJ;Benoni, G;Pelletier, JC;Reitz, AB;Lairson, LL;Houseknecht, KL;Smith, GR;Dickerson, TJ;
Product: SNAPtide® Peptide Substrate (FITC/DABCYL) for C. botulinum Type A Neurotoxin
Botulinum neurotoxins (BoNT) are the most potent toxins known and a significant bioterrorist threat.....
A high-throughput-compatible FRET-based platform for identification and characterization of botulinum neurotoxin light chain modulators
Journal Of Visualized Experiments : JoVE
Cagli, D;Bompiani, KM;Krutein, MC;apek, P;Dickerson, TJ;
Product: SNAPtide® Peptide Substrate (FITC/DABCYL) for C. botulinum Type A Neurotoxin
Botulinum neurotoxin (BoNT) is a potent and potentially lethal bacterial toxin that binds to host mo....
The Use of Fragment-Based Lead Discovery Towards the Design and Development of Metalloenzyme Inhibitors
Thesis
Sardo, JL;
Product: MAPKKide® Peptide Substrate (DABCYL/FITC) for Anthrax Lethal Factor
Bioluminescence assay for the highly sensitive detection of botulinum neurotoxin A activity
Analyst
Stevens, GB;Silver, DA;Zgaga-Griesz, A;Bessler, WG;Vashist, SK;Patel, P;Achazi, K;Strotmeier, J;Worbs, S;Dorner, MB;Dorner, BG;Pauly, D;Rummel, A;Urban, GA;Krueger, M;
Product: SNAPtide® Peptide Substrate (FITC/DABCYL) for C. botulinum Type A Neurotoxin
This article describes a novel bioluminescence assay for detecting the proteolytic activity of Botul....
Substrates and controls for the quantitative detection of active botulinum neurotoxin in protease-containing samples
Analytical Chemistry
Bagramyan, K;Kaplan, BE;Cheng, LW;Strotmeier, J;Rummel, A;Kalkum, M;
Product: SNAPtide® Peptide Substrate (FITC/DABCYL) for C. botulinum Type A Neurotoxin
Botulinum neurotoxins (BoNTs) are used in a wide variety of medical applications, but there is limit....
Comparison of fluorigenic peptide substrates PL50, SNAPTide, and BoTest A/E for BoNT/A detection and quantification: exosite binding confers high-assay sensitivity.
Journal Of Biomolecular Screening
Ouimet, T;Duquesnoy, S;Poras, H;Fourni-Zaluski, MC;Roques, BP;
Product: SNAPtide® Peptide Substrate (FITC/DABCYL) for C. botulinum Type A Neurotoxin
Detection and quantification of low doses of botulinum toxin serotype A (BoNT/A) in medicinal prepar....
Development of a fluorescence internal quenching correction factor to correct botulinum neurotoxin type A endopeptidase kinetics using SNAPtide
Analytical Chemistry
Feltrup, TM;Singh, BR;
Product: Unquenched Calibration Peptide for SNAPtide® 521 Substrate for C. botulinum Type A Neurotoxin
Botulinum neurotoxins (BoNTs), which are highly toxic proteins responsible for botulism, are produce....
Metal ion-mediated inactivation and small molecule inhibition of the metalloprotease in botulinum neurotoxin A
Thesis
Feng, M;
Product: SNAPtide® Peptide Substrate (o-Abz/Dnp) for C. botulinum Type A Neurotoxin
Sensitive and Specific Bifunctional Assay for Botulinum Neurotoxin Type A
List Labs POSTER - Presented at the 49th Annual Interagency Botulinum Research Coordinating Committee Meeting, September 2012 in Baltimore Maryland
Suryadi, K.; Christian, T.; Shine, N.
Product: Receptor for Clostridium botulinum Type A Neurotoxin, GST-SV2c luminal domain
Background: The purpose of this study is to develop a highly specific and sensitive method to assess....
Evaluation of Three VAMPtide Substrates for Botulinum Neurotoxin Type B
List Labs POSTER - Presented at the 49th Annual Interagency Botulinum Research Coordinating Committee Meeting, September 2012 in Baltimore Maryland
Shine, N.; Ouimet, T.
Product: VAMPtide® Peptide Substrate (o-Abz/Dnp) Substrate for C. botulinum Type B Neurotoxin
Background: Peptide substrates which are specific for Botulinum neurotoxin type B (BoNT/B) have been....
Mechanisms of SNAP-25 Association with Botulinum Neurotoxin Light Chain A and SNARE Proteins
Thesis
Sultani, M;
Product: SNAPtide® Peptide Substrate (o-Abz/Dnp) for C. botulinum Type A Neurotoxin
Development of highly sensitive chemiluminescence enzyme immunoassay based on the anti-recombinant HC subunit of botulinum neurotoxin type A monoclonal antibodies
Analytica Chimica Acta
Liu, Z;Song, C;Li, Y;Liu, F;Zhang, K;Sun, Y;Li, H;Wei, Y;Xu, Z;Zhang, C;Yang, A;Xu, Z;Yang, K;Jin, B;
Product: SNAPtide® Peptide Substrate (o-Abz/Dnp) for C. botulinum Type A Neurotoxin
Botulinum neurotoxins (BoNTs) are the most poisonous substances ever known. The early detection of t....
Sensitive Detection of Botulinum Neurotoxin Type A Using High Affinity Polyclonal Antibodies
List Labs POSTER - Presented at the 7th International Conference on Basic and Therapeutic Aspects of Botulinum and Tetanus Toxins, Santa Fe, NM.
Suryadi, K.; Christian, T.; Shine, N.
Product: SNAPtide® Peptide Substrate (o-Abz/Dnp) for C. botulinum Type A Neurotoxin
Purpose of Study: The purpose of this study was to determine if a polyclonal antibody directed towar....
New FRET Substrate For Botulinum Neurotoxin Type A
List Labs POSTER - Presented at the 7th International Conference on Basic and Therapeutic Aspects of Botulinum and Tetanus Toxins, October 2011 Santa
Shine, N.; Suryadi, K.
Product: SNAPtide® Peptide Substrate (FITC/DABCYL) for C. botulinum Type A Neurotoxin
Purpose of Study: A new FRET peptide substrate for botulinum toxin type A (BoNT/A), marketed as SNAP....
New SV2c Construct for Use in Binding and Detecting Botulinum Neurotoxin Type A
List Labs POSTER - Presented at the 7th International Conference on Basic and Therapeutic Aspects of Botulinum and Tetanus Toxins, October 2011
Christian, T.; Suryadi, K.; Shine, N.
Product: SNAPtide® Peptide Substrate (o-Abz/Dnp) for C. botulinum Type A Neurotoxin
Purpose of Study:The purpose of this study was to express and purify the luminal domain loop of huma....
Ultra Sensitive HPLC Detection Assay for Botulinum Neurotoxin Type A
List Labs POSTER - Presented at the 47th Annual Interagency Botulinum Research Coordinating Committee Meeting, November 2010, Atlanta, GA
Christian, T.; Suryadi, K.; Shine, N.
Product: SNAPtide® Peptide Substrate (o-Abz/Dnp) for C. botulinum Type A Neurotoxin
The botulinumneurotoxins are among the most potent toxins in nature. They are synthesized as single ....
Evaluation of a Small Peptide Inhibitor and A Control Peptide for Botulinum Neurotoxin, Type A
List Labs POSTER - Presented at the 47th Annual Interagency Botulinum Research Coordinating Committee Meeting, November 2010 in Atlanta, GA
Shine, N.; Suryadi, K.; Christian, T.
Product: SNAPtide® Peptide Substrate (o-Abz/Dnp) for C. botulinum Type A Neurotoxin
Botulinum neurotoxins are among the most toxic substances known to man. Four of the seven immunologi....
Characterization of SNARE Cleavage Products Generated by Formulated Botulinum Neurotoxin Type-A Drug Products
Toxins
Hunt T, Rupp D, Shimizu G, Tam K, Weidler J, Xie J.
Product: SYNTAXtide® (o-Abz/Dnp) Peptide Substrate for C. botulinum Type C Neurotoxin
The study evaluated substrate cleavage product(s) generated by three botulinum neurotoxin serotype A....
FRET Peptide Substrates for BotulinumNeurotoxins Types A, B, C, and E
List Labs POSTER - Presented at the 46th Annual Interagency Botulinum Research Coordinating Committee Meeting, October 2009 in Alexandria, VA
Shine, N.; Endrukaite,E.; Christian, T.
Product: VAMPtide® Peptide Substrate (o-Abz/Dnp) Substrate for C. botulinum Type B Neurotoxin
Thebotulinumneurotoxinsareamongthemosttoxicsubstancesknowntoman.Fouroftheseven immunologicallydistin....
Sensitive, In Vitro, Bifunctional, Potency Assay For Botulinum Neurotoxin Type A
List Labs POSTER - Presented at the 46th Annual Interagency Botulinum Research Coordinating Committee Meeting, October 2009 in Alexandria, VA.
Christian, T.; Shine, N.
Product: SNAPtide® Peptide Substrate (o-Abz/Dnp) for C. botulinum Type A Neurotoxin
Botulinum toxin progresses through a three step process leading to the interruption of synaptic tran....
Functional Assay for Botulinum Neurotoxin Type A Utilizing the Neuronal Receptor Protein SV2c.
List Labs POSTER - Presented at the 45th Annual Interagency Botulinum Research Coordinating Committee Meeting, September 2008 in Philadelphia, PA.
Christian, T.; Rummel, A.; Shine, N.
Product: SNAPtide® Peptide Substrate (o-Abz/Dnp) for C. botulinum Type A Neurotoxin
Botulinum toxin progresses through a three step process leading to the interruption of synaptic tran....
Capture Assay for Botulinum Neurotoxin Type A Utilizing the Neuronal Receptor Protein SV2c.
List Labs POSTER - Presented at the 6th International Conference on Basic and Therapeutic Aspects of Botulinum and Tetanus Toxins, June 2008 in Baveno
Christian, T.; Shine, N.
Product: SNAPtide® Peptide Substrate (o-Abz/Dnp) for C. botulinum Type A Neurotoxin
Recent biochemical and molecular genetic studies have established synaptic vesicle glycoprotein 2c (....
New High Affinity Antibodies Against Botulinum Neurotoxin Type A
List Labs POSTER - Presented at the 6th Annual ASM Biodefense and Emerging Diseases Research Meeting, Baltimore, MD
Christian, T.; Shine, N.; Crawford, K.
Product: SNAPtide® Peptide Substrate (o-Abz/Dnp) for C. botulinum Type A Neurotoxin
New high affinity antibodies against Botulinum Neurotoxin Type A have been developed in chickens. Pr....
FRET Peptide Substrates for the Botulinum Toxins Type A, B, and E and for Anthrax Lethal Factor.
List Labs POSTER - Presented at the 5th Annual ASM Biodefense and Emerging Diseases Research Meeting, February 2007 in Washington, D.C.
Shine, N., Crawford, K.
Product: SNAPtide® Peptide Substrate (o-Abz/Dnp) for C. botulinum Type A Neurotoxin
SNAP-Etide, a FRET Substrate for Botulinum Toxin Type E
List Labs POSTER - Presented at the 43nd Annual IBRCC, November 2006 in Silver Springs, Maryland
Shine, N.; Christian, T.; Primak, Y.
Product: SNAP Etide® Peptide Substrate (o-Abz/Dnp) for C. botulinum Type E Neurotoxin
Botulinum neurotoxins have seven distinct serotypes, four of which (types A, B, E and F) cause botul....
Physical Characteristics of rLF and rPA: Effects on Enzymatic : Effects on Enzymatic Activity and Binding
List Labs POSTER - Presented at Bacillus Act 2005, September 25-29, 2005 in Sante Fe, New Mexico.
Shine, N., Le, C., Eaton, L., Crawford, K.
Product: Unquenched Calibration Peptide for MAPKKide® 530 for Anthrax Lethal Factor
Bacillus anthracis exotoxin is composed of three components; protective antigen (PA), lethal factor ....
Efficient synthetic inhibitors of anthrax lethal factor
Proceedings of the National Academy of Sciences of the United States of America
Forino M, Johnson S, Wong TY, Rozanov DV, Savinov AY, Li W, Fattorusso R, Becattini B, Orry AJ, Jung D, Abagyan RA, Smith JW, Alibek K, Liddington RC, Strongin AY, Pellecchia M
Product: MAPKKide® Peptide Substrate (o-Abz/Dnp) for Anthrax Lethal Factor
Inhalation anthrax is a deadly disease for which there is currently no effective treatment. Bacillus....
Comparison of Activity of Botulinum Neurotoxin Type A Holotoxin and Light Chain Using SNAPtide FRET Substrates.
List Labs POSTER - Presented at the 5th International Conference on Basic and Therapeutic Aspects of Botulinum and Tetanus Toxins, June 2005 in Denver
Christian, T.; Shine, N.; Eaton, L.; Crawford, K.
Product: SNAPtide® Peptide Substrate (o-Abz/Dnp) for C. botulinum Type A Neurotoxin
The botulinum neurotoxins are composed of two subunits, a 100 kD heavy chain and a 50 kD light chain....
INTERNALLY QUENCHED FLUOROGENIC SUBSTRATES FOR ANTHRAX LETHAL FACTOR
List Labs POSTER - Presented at the 5th International Conference on Anthrax, March 30, 2003 in Nice, France
Shine, N., Eaton, L., Crawford, K.
Product: MAPKKide® Peptide Substrate (DABCYL/FITC) for Anthrax Lethal Factor
Lethal factor (LF) is the enzymatic component of anthrax lethal toxin which specifically cleaves the....
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