List Labs scours the internet monthly, looking for citations referencing our products. We are highly intrigued by, and love to investigate the different ways researchers use our products. Scientists world-wide have used our toxins for research and have produced interesting results.

List Labs History of working with Botulinum Neurotoxin

List Labs has developed sensitive assays used by pharmaceutical companies, research universities and government agencies to detect Botulinum Toxin Type A in complex samples and to screen for potential inhibitors. List Labs also has a bifunctional assay for Botulinum Type A which measures SV2c receptor binding enzymatic activity.

List Labs is a well-known quality provider of bacterial toxins for research. We harness our vast experience, expertise, state of the art equipment and facilities to bring researchers some of the purest products available.

You can purchase List Labs Botulinum Neurotoxin research reagents here, and view our full catalog of products here.

View our Botulinum neurotoxin citations infographic below:

By: Rachel Berlin, Marketing Manager

The List Labs website hosts a library of scientific article abstracts related to the research performed using our products called the Citations Page. Visitors can search this library to learn how others have used List Labs’ reagents in their research. This valuable resource is updated monthly with new articles from a wide variety of publications. Check out a few recent articles below:

Botulinum Neurotoxin

• High Yield Preparation of Functionally Active Catalytic-Translocational Domain Module of Botulinum Neurotoxin Type A That Exhibits Uniquely Different Enzyme Kinetics 
• Augmentation of VAMP-catalytic activity of botulinum neurotoxin serotype B does not result in increased potency in physiological systems
• Detection and Quantification of Biologically Active Botulinum Neurotoxin Serotypes A and B using Förester Resonance Energy Transfer-based Quantum Dot Nanobiosensor 

Carrier Proteins

• Complexation hydrogels as potential carriers in oral vaccine delivery systems 
• Efficacy, but not antibody titer or affinity, of a heroin hapten conjugate vaccine correlates with increasing hapten densities on tetanus toxoid, but not on CRM197 carriers

Clostridium difficile toxin

• Catch-slip behavior observed upon rupturing membrane-cytoskeleton bonds
• Immunization with Recombinant TcdB-Encapsulated Nanocomplex Induces Protection against Clostridium difficile Challenge in a Mouse Model
• Clostridium difficile chimeric toxin receptor binding domain vaccine induced protection against different strains in active and passive challenge models 

Lipopolysaccharide (LPS)

• A quantitative method for microstructural analysis of myelinated axons in the injured rodent brain
• Innate immune responses of equine monocytes cultured in equine platelet lysate
• Cationic peptides from peptic hydrolysates of rice endosperm protein exhibit antimicrobial, LPS-neutralizing, and angiogenic activities

Diphtheria toxin

• Auditory Neuropathy after Damage to Cochlear Spiral Ganglion Neurons in Mice Resulting from Conditional Expression of Diphtheria Toxin Receptors
• Monocytes Promote Crescent Formation in Anti-Myeloperoxidase Antibody-Induced Glomerulonephritis
• Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis

Don’t see the reagent you’re interested in? You can search the citations by product, year, publication, or by the type of cell, animal, assay, protein or research. Check it out today!

By: Allisa Clemens, Production Biochemist

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My name is Allisa Clemens, and I started working at List Labs about 2 years ago as a Production Biochemist within the Purification team. Prior to working at List Labs I was a full time graduate student and Teaching Associate in the Chemistry department at San Jose State University. While working on my research for my Master’s thesis, I quickly learned how scarce funding for equipment, reagents, and supplies can slow down progress.

In 2016, I began the Marguerite E. Bourez Donations for Academic Research program here at List Labs, to celebrate and pass on the generous spirit of my Aunt Marguerite, who, when I had nothing, gave me a home and enabled me to go to college, and eventually complete my Master of Science in Chemistry. Without her generous support, my own contribution to the scientific community might not have been possible. And I am not alone; over the years she has helped many people just like me.  Being a rocket scientist herself, she knows how education can not only present more career opportunities, but also enrich your life. My hope that this program will reflect her commitment to giving and advancing education.

Donations Program Gives to Deserving Academic Research Labs

The Rascón Research Group is one of such research groups. I first met Dr. Rascón when I took his graduate enzymology course at San Jose State University. No single academic course has made more of an impact in changing the way I think as a student and as a researcher. Dr. Rascón has been very generous with me over the years in offering me his time and expertise. So naturally, when I had the opportunity to give back, he was the first person I thought of. According to Dr. Rascón, “We at SJSU strive to provide research opportunities to our undergraduate and graduate students, but sometimes reagents and columns are hard to come by. With these columns we have been able to purify a couple of our proteolytic enzymes and have been able to show students the purification process.” The Rascón Research group is working to investigate and develop serine protease inhibitors for the Aedes aegypti mosquito. This invasive species is a vector for dengue fever, chikungunya virus, zika virus, and yellow fever read. The work his research group does provides invaluable information for vector control of these potentially deadly viruses.

Another research group we are proud to support is the Miller Conrad lab, which uses organic chemistry and molecular biology techniques to understand and combat virulence in the pathogen Pseudomonas aeruginosa. This opportunistic pathogen is responsible for an estimated 51,000 hospital acquired infections a year, with roughly 13% being multidrug resistant. As antibiotic resistance continues to be a global threat to health, we are eager to support this much needed humanitarian work.

Recent donations

Mills College – has a strong commitment for the advancement of women. Mills works hard to offer an affordable education to those and prides themselves on accepting those who have a desire and the qualification to attend, so over 98% of their undergraduate students received financial aid. Caroline Harmon, a Production Biochemist with List Labs, was one of these proud Alumnae. After being involved in a research project her first year, she was inspired to pursue biochemical research. The donations given to Mills College will aid the new biochemistry professor, Ana Mostafavi, to set up her lab. Professor Mostafavi is currently at the Muir Lab at Princeton and will be joining Mills in the Fall of 2019. Giving Mills equipment that they may not have been able to attain themselves, as Women’s colleges have seen a loss in financial donations. We hope that this donation will aid in training future researchers and promoting women in science, and will greatly improve these undergraduate students’ education.

To date, the Marguerite E. Bourez Donations for Academic Research program at List Labs has given over $100,000 worth of supplies, reagents, and equipment to a number of well deserving academic research labs. Included in the donations were a variety of AKTA columns and chromatography resins, various types of bacteria culture media, pipette tips, vials with stoppers, filters and gloves. If you would your academic research lab like to be considered to receive donations please contact Shawn Lyles.

List Labs Dedicated to Providing Reagents to Advance Research

List Labs’ heart is in the science and discovery of innovative research reagents, and we function to serve the global research community. List Biological Laboratories, Inc. is dedicated to providing research reagents to advance the understanding of disease and to further the development of vaccines, therapeutics and diagnostics. I am happy to have been able to make a small contribution on behalf of List Labs to the student and faculty research being performed by these outstanding research groups.

If you know of an academic research group that you would like to be considered for our donation program, please contact List Labs by emailing me with an explanation for the types of supplies, equipment, or reagents needed and a brief description of the research being performed. Donation of all equipment, supplies and reagents is contingent on availability.