List Labs Bacterial Toxin & Vaccine Research Blog

Microbiome Research Requires GMP Facilities

May 15, 2017

By: douano@listlabs.com

By: Stacy Burns-Guydish, Ph.D., Senior Director, Microbiology The human body is home to a vast ecosystem of microbes, called the microbiome. Research is shedding light on the importance of the microbiome as a benefactor to our health and development. Perturbation of the microbiome has been associated with a growing number of diseases including inflammatory bowel […]

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Carrier Protein Used in Life-Changing Research

March 27, 2017

By: douano@listlabs.com

By: Mary N. Wessling, Ph.D. ELS Cross-Reacting Materials: The Motor Behind Conjugate Vaccines Vaccines in history The history and practice of vaccination as protection against viral infection is often thought to begin with Edward Jenner’s discovery that cowpox, a viral infection of cows, prevented smallpox in humans. However, it had long been suspected that survivors […]

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List Labs Citation Library – A New Tool Available To Aid In Your Research Needs

March 13, 2017

By: douano@listlabs.com

By: Grace Ayabe, Technical Support Specialist List Labs recently launched a citation library in our website to provide you with research papers that utilize List Labs products; these papers can provide supplemental information for your research. We currently have over 1800 citations, from around the world, available for viewing. The number of available citations will […]

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Endotoxins: Potency Testing and Low Endotoxin Recovery (LER/LLR) in Pharmaceutical Applications

March 6, 2017

By: douano@listlabs.com

By: Md. Elias, Ph.D, Senior Scientist What are Endotoxins? Endotoxins (aka lipopolysaccharide, LPS or lipoglycan) are part of the outer membrane of Gram-negative bacteria consisting of a lipid moiety and a polysaccharide moiety, the latter is composed of an inner core, outer core and O-antigen joined by covalent bonds1. In animals the lipid part of […]

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C. Difficile Toxins A and B Support Development of Diagnostics

February 14, 2017

By: List Labs

By: Mary N. Wessling, Ph.D. ELS List Biological Laboratories, Inc.’s products are being used to confront one of the most pressing problems in health care today: stopping the worldwide spread of illness caused by Clostridium difficile (CD, C Difficile Toxin), a gram-positive, spore-forming anaerobic bacillus. The spores are highly resistant to adverse environmental conditions and are […]

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Cell Ablation Using Diphtheria Toxin (DT): Studying Cellular Regeneration in Live Animals

December 12, 2016

By: List Labs

By: Suzanne Canada, Ph.D. Diphtheria toxin is an important tool used for selective killing (ablation) of cells for research purposes. Using this technique, dubbed “toxin receptor–mediated cell knockout” when it was first used [1], researchers can selectively remove a specific type of cell in a live mouse without having to generate transgenic “knockout” animals, which […]

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