Citations

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4694 total record number 67 records this year

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4694 citations found

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Critical role of CD206+ macrophages in organizing anti-tumor immunity

Ray, A;Hu, KH;Kersten, K;Kuhn, NF;Samad, B;Combes, AJ;Krummel, MF;

Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae

  • Diphtheria toxin administration:

    For depletion of CD206-expressing macrophages, 500ng (20ng/g body weight, assuming an average 25g weight for each mouse) diphtheria toxin (DTx;List Biological Laboratories) in 100µL 1X PBS was injected intraperitoneally into each mouse – for both Csf1rCre; Mrc1(CD206) LSL-Venus-DTR (DTR) and Mrc1(CD206) LSL-Venus-DTR (WT) groups – at every time point. For the early depletion regime, injections were started 2 days after adoptive transfer of T cells and continued every 2-3 days till endpoint, while for the late depletion regime, injections began at d10 after T cell injection and continued till endpoint. For testing the effects of DTx in tumor-free tissue, similar dosing of DTx as the early depletion regime was implemented without tumor injection, and the skin (ectopic tumor site) and skin-draining lymph nodes were isolated for analysis. Mice were found to be healthy and without frank health issues with 6 doses of 500ng DTx (early depletion regime), but were monitored nevertheless throughout the experiment, as per IACUC guidelines.

    Product #150 – Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae

Cutting Edge: Serpine1 Negatively Regulates Th1 Cell Responses in Experimental Autoimmune Encephalomyelitis

Akbar, I;Tang, R;Baillargeon, J;Roy, AP;Doss, PMIA;Zhu, C;Kuchroo, VK;Rangachari, M;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae

  • Immunization and in vivo treatment

    All immunization procedures were conducted in the rear footpad with 20 µL injection volume per
    footpad. Mice were immunized as indicated in each Figure with 5 µg low-endotoxin OVA (Worthington
    Biochemical Corporation) mixed with either 50 µg papain (P4762, Sigma), 10 µL FCA (F5881, Sigma),
    or 10 µL alum (77161, Thermo Scientific) in phosphate-buffered saline (PBS). For DC depletion, mice
    were injected i.p. with 500 ng DT in PBS (List Biological Laboratories)
    at indicated time-points. …

    T cell priming assays

    … Mice with DTR expression were treated with DT as indicated in each Figure. …

    Product #150 – Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae

Targeting PGLYRP1 promotes antitumor immunity while inhibiting autoimmune neuroinflammation

Schnell, A;Huang, L;Regan, BML;Singh, V;Vonficht, D;Bollhagen, A;Wang, M;Hou, Y;Bod, L;Sobel, RA;Chihara, N;Madi, A;Anderson, AC;Regev, A;Kuchroo, VK;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Characterizing a Silver Nanoparticle-Based Electrochemical Biosensor for Shiga Toxin Detection

Patel, D;Hansen, M;Lambert, C;Hegde, S;Jayamohan, H;Gale, B;Sant, H;

Product: Shiga Toxin 1 from Escherichia coli

Longitudinal in vivo evaluation of retinal ganglion cell complex layer and dendrites in mice with experimental autoimmune encephalomyelitis

Qian, Z;Zheng, K;Xu, Y;Chen, S;Chen, S;Liang, J;Cao, Y;Ng, TK;Qiu, K;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Dysregulated Immunity to Clostridioides difficile in IBD Patients Without a History of Recognized Infection

Cook, L;Wong, MQ;Rees, WD;Schick, A;Lisko, DJ;Lunken, GR;Wang, X;Peters, H;Oliveira, L;Lau, T;Mah, R;Bressler, B;Levings, MK;Steiner, TS;

Product: Toxin B Toxoid from Clostridium difficile

  • Reagents

    C. difficile TcdB toxoid (formaldehyde inactivated; List Biological Laboratories Inc) was used at 5 μg/mL.

Discovery of Clinical Candidate NT-0796, a Brain-Penetrant and Highly Potent NLRP3 Inflammasome Inhibitor for Neuroinflammatory Disorders

Harrison, D;Billinton, A;Bock, MG;Doedens, JR;Gabel, CA;Holloway, MK;Porter, RA;Reader, V;Scanlon, J;Schooley, K;Watt, AP;

Product: Anthrax Protective Antigen (PA), Recombinant from B. anthracis

Global lactylome reveals lactylation-dependent mechanisms underlying TH17 differentiation in experimental autoimmune uveitis

Fan, W;Wang, X;Zeng, S;Li, N;Wang, G;Li, R;He, S;Li, W;Huang, J;Li, X;Liu, J;Hou, S;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer