List Labs Bacterial Toxin & Vaccine Research Blog

How List Biological Laboratories, Inc. got its start

August 29, 2017

By: dpinkston@listlabs.com

The origin of businesses is often an interesting story. List Biological Laboratories is no exception. The company was founded in 1978 by Linda Shoer. Linda was an entrepreneurial scientist in Silicon Valley, who’d been relocated with her husband from Boston. She had an idea for a company and leveraged an initial order into a loan […]

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The Importance of Lyophilization for Bacteria Production

August 7, 2017

By: douano@listlabs.com

By: Mary N. Wessling, Ph.D. ELS What is Lyophilization? Protecting the activity of enzyme products and the viability of bacterial cultures that are used in scientific experimentation is an area where List Biological Laboratories is a leader. Lyophilization has been the most extensively used technique for maintaining the integrity of biopharmaceuticals. Lyophilization (otherwise known […]

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Tetanus Toxin – Model Antigen and Protein Carrier

July 17, 2017

By: douano@listlabs.com

By: Mary N. Wessling, Ph.D. ELS Tetanus Toxin’s Use as a Protein Carrier and Antigen Tetanus toxin (TT) is the major virulence factor of the Gram-positive bacterium Clostridium tetani. Infection with this bacterium in unvaccinated persons produces muscle spasms by binding to nerve endings and moving throughout the nervous system in a specific way. Eventually, […]

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How is Cholera Toxin Used in Scientific Research?

June 5, 2017

By: douano@listlabs.com

By: Mary N. Wessling, Ph.D. ELS Cholera Toxin: Dual Roles in Disease and Scientific Advancement In 2010, Sanchez et al published an article with the puzzling title “Cholera toxin—A foe & a friend. ” The cholera toxin, a complex of two units produced by the pathogen Vibrio cholerae clearly plays the “foe” role [1]. […]

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Microbiome Research Requires GMP Facilities

May 15, 2017

By: douano@listlabs.com

By: Stacy Burns-Guydish, Ph.D., Senior Director, Microbiology The human body is home to a vast ecosystem of microbes, called the microbiome. Research is shedding light on the importance of the microbiome as a benefactor to our health and development. Perturbation of the microbiome has been associated with a growing number of diseases including inflammatory bowel […]

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Carrier Protein Used in Life-Changing Research

March 27, 2017

By: douano@listlabs.com

By: Mary N. Wessling, Ph.D. ELS Cross-Reacting Materials: The Motor Behind Conjugate Vaccines Vaccines in history The history and practice of vaccination as protection against viral infection is often thought to begin with Edward Jenner’s discovery that cowpox, a viral infection of cows, prevented smallpox in humans. However, it had long been suspected that survivors […]

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