Bacterial Toxin Research Citations

July 1, 2024

Cns Neuroscience & Therapeutics

Yang, X;Zhangyi, Z;Yu, A;Zhou, Q;Xia, A;Qiu, J;Cai, M;Chu, X;Li, L;Feng, Z;Luo, Z;Sun, G;Zhang, J;Geng, M;Chen, S;Xie, Z;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

e experimental autoimmune encephalomyelitis (EAE), we administered myelin oligodendrocyte glycoprotein (MOG) (#51716, GL Biochem (Shanghai), Ltd.) and pertussis toxin (PTX) (#180, List Biological) to mice. On day 0, the mice were randomly assigned to different groups (n?=?10). After anesthetizing the mice with isoflurane, we subcutaneously injected an emulsion containing 2?mg/mL MOG35-55 and 4?mg/mL complete Freund's adjuvant (CFA) in equal volumes (10??L each), which had been homogenized for 1?h in a 40?mL brown glass vial. Simultaneously, we intraperitoneally injected 200??L (200?ng) of a diluted PTX solution. After 48?h, th

July 1, 2024

Cancer Immunology Research

Dong, B;Obermajer, N;Tsuji, T;Matsuzaki, J;Bonura, CM;Sander, C;Withers, H;Long, MD;Chavel, C;Olejniczak, SH;Minderman, H;Kirkwood, JM;Edwards, RP;Storkus, WJ;Romero, P;Kalinski, P;

Product: Enterotoxin Type B from Staphylococcus aureus

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PubMed ID: 38949179

Partner Therapeutics; IL-4, IL-1?, TNF?, and IFN-? were purchased from Miltenyi; IL-6 was purchased from R&D Systems; IFN-? (Intron A- IFN-?-2b) and IL-2 (Proleukin aldesleukin) were purchased from McKesson; PGE2 and poly-I:C were purchased from Sigma-Aldrich; IL-7 and IL12p70 were purchased from Peprotech; Staphylococcus Enterotoxin B (SEB) was purchased from List Labs; Dynabeads Human T-Activator CD3/CD28 was purchased from Gibco; purified Streptavidin was purchased from Biolegend to crosslink biotinylated-antibodies for short-term CTL stimulation. Oxaliplatin and cis-Diammineplatinum(II) Dichloride (Cisplatin) were purchased from Sigma-Aldrich

June 28, 2024

Journal Of Controlled Release : Official Journal Of The Controlled Release Society

Cao, F;Liang, K;Tang, WW;Ni, QY;Ji, ZY;Zha, CK;Wang, YK;Jiang, ZX;Hou, S;Tao, LM;Wang, X;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

popolysaccharide (LPS) and complete Freund's adjuvant (CFA) were purchased from Sigma-Aldrich (St. Louis, Missouri, USA). Pertussis toxin (PTX) was purchased from List Biological Labs (USA). Human intercellular retinol-binding protein (IRBP1169-1191, PTARSVGAADGSSWEGVGVVPDV) was purchased from Sangon Bioengineering Technology and Services Co., Ltd. (Shanghai, China). All primary antibodies for immunofluorescenc

June 27, 2024

Research Square

Wang, L;Zhao, T;Shang, S;Lu, X;

Product: Pertussis Toxin from B. pertussis, Lyophilized (Salt-Free)

SCs were seeded into petri dishes t a density of 1×106/ml and cultured overnight. Then, the cells were either treated with different concentrations of BHB for 1 day or pretreated with 500 ng/ml PTX (List Biological, 181), 10 µM gallein (Topscience, T3040), 20 µM NF023 (Abcam, ab120454) or 100 nM U0126 (Sigma, U120) separately for 1 hour, followed by treatment with 0.02 mM BHB for 2 days. Pictur ... SCs were seeded into petri dishes t a density of 1×106/ml and cultured overnight. Then, the cells were either treated with different concentrations of BHB for 1 day or pretreated with 500 ng/ml PTX (List Biological, 181), 10 µM gallein (Topscience, T3040), 20 µM NF023 (Abcam, ab120454) or 100 nM U0126 (Sigma, U120) separately for 1 hour, followed by treatment with 0.02 mM BHB for 2 days. Pictur

June 26, 2024

Frontiers In Endocrinology

Cao, Z;Zhao, Y;Liu, R;Yan, X;Wang, J;Chen, N;

Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae

To induce deletion of Cre-positive cells, mice were injected daily with 100 ng/mouse/day of diphtheria toxin (DT) (Biological List Laboratories, Cat#150) for 5 days via the

June 26, 2024

Biorxiv

Ghena, N;Anderson, S;Roberts, J;Irvin, E;Schwakopf, J;Bosco, A;Vetter, M;

Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae

Science,A15520) was dissolved in corn oil and 10% DMSO and administered to postnatal pups by intraperitoneal injection on P2-P4 at 0.125 mg/g body weight. Diphtheria Toxin (List Labs, #150) was dissolved in PBS and administered to postnatal pups by intraperitoneal injection at

June 26, 2024

Nature Communications

Fazazi, MR;Doss, PMIA;Pereira, R;Fudge, N;Regmi, A;Joly-Beauparlant, C;Akbar, I;Yeola, AP;Mailhot, B;Baillargeon, J;Grenier, P;Bertrand, N;Lacroix, S;Droit, A;Moore, CS;Rojas, OL;Rangachari, M;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

is extract (BD Difco). On day 0 and day 2 post-immunization, mice received 200?ng pertussis toxin (List Biological Laboratories) intraperitoneally. For p19 blockade, mice were administered anti-p19 (clone G23-8) or isotype (rIgG1, clone HRPM; both BioXcell), 1?mg, on d-1 and d+6 post-immunization56. For the comparison of Th17 cell pathogenicity in the presence of WT or IgH[MOG] B cells (Fig. 3d), 10-week-old NOD.Scid mice were first passively infused i.v. with 2?×?106 CD19+ WT or IgH[MOG] B cells from unimmunized donors. Fourteen days post-infusion, 2?

June 20, 2024

Journal Of Integrative Neuroscience

Xiang, W;Bai, S;Wang, K;Peng, J;Wang, Z;Han, L;Xie, C;Guan, Y;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

lete Freunds adjuvant (BD Difco, Franklin Lakes, NJ, USA) at 4 sites. Then, they were injected (i.p.) with 200 ng pertussis toxin (List Biological Laboratories, Campbell, CA, USA) on days 4 and 7 after immunization. Mice started to receive injections (i.p.) of NMO-IgG on day 0 for 8 consecutive days (5 mg NMO-IgG/day). The control group received injections of adjuvant, pertussis toxin, and the same amount of control-IgG. 2.3 Detection of Motor Impairments

June 19, 2024

Cell Reports

Nasrallah, K;Berthoux, C;Hashimotodani, Y;Chávez, AE;Gulfo, MC;Luján, R;Castillo, PE;

Product: Botulinum Neurotoxin Type B Light Chain, Recombinant

ANA-12 Tocris Bioscience Cat#4781 Botulinum toxin-B List biological Cat# 620A H89 dihydrochloride Tocris Bioscience Cat#2910

June 18, 2024

Medrxiv

Emmenegger, M;Zografou, C;Dai, Y;Hoyt, L;Gudneppanavar, R;Chincisan, A;Rehrauer, H;Noé, F;Zajac, N;Meisl, G;Schneider, M;Nguyen, H;Höpker, K;Knowles, T;Sospedra, M;Martin, R;Ring, A;Leeds, S;Eisenbarth, S;Egan, M;Bruscia, E;Aguzzi, A;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

was dissolved in 200 µl of 0.2 mol sodium bicarbonate buffer with or without 10 µg of cholera toxin (List Biologicals, Campbell, Calif) as an adjuvant and delivered by oral gavage. Blood was collected from the retro-orb

Bacterial Toxin Research Citations

GV-971 attenuates the progression of neuromyelitis optica in murine models and reverses alterations in gut microbiota and associated peripheral abnormalities

NK Receptor Signaling Lowers TCR Activation Threshold, Enhancing Selective Recognition of Cancer Cells by TAA-Specific CTLs

Polyvinylpyrrolidone-curcumin nanoparticles with immune regulatory and metabolism regulatory effects for the treatment of experimental autoimmune uveitis

BHB promotes the proliferation of neural stem cells by activating the Erk1/2- MAPK pathway and changing histone modification patterns

Identification of ibuprofen targeting CXCR family members to alleviate metabolic disturbance in lipodystrophy based on bioinformatics and in vivo experimental verification

CD11c-expressing microglia are transient, driven by interactions with apoptotic cells

Myelin-reactive B cells exacerbate CD4+ T cell-driven CNS autoimmunity in an IL-23-dependent manner

Human NMO-IgG Induced Different Pathological and Immunological Changes in the CNS and Peripheral Tissues of Mice

Retrograde adenosine/A2A receptor signaling facilitates excitatory synaptic transmission and seizures

The Cystic Fibrosis Transmembrane Regulator Controls Tolerogenic Responses to Food Allergens in Mice and Humans