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3951 citations found

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Inflammasome-induced extracellular vesicles harbour distinct RNA signatures and alter bystander macrophage responses

Budden, CF;Gearing, LJ;Kaiser, R;Standke, L;Hertzog, PJ;Latz, E;

Product: Anthrax Protective Antigen (PA), Recombinant from B. anthracis

Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae

  • 2.1. Mouse model and treatment

    Vglut3DTR/+ mice were generated in our lab. We used the CRISPR/Cas9 approach to connect DTR to the C-terminus of Vglut3 via the P2A peptide. PCR and Southern blot methods were used to screen out the mice with the correct recombination. Lgr5CreERT2/+ (Stock #008875) and Rosa26-tdTomato (Stock #007914) mice were purchased from the Jackson Laboratory. The primers used for genotyping Lgr5creERT2/+, Rosa26-tdTomato and Vglut3DTR/+ mice are listed in Supplementary table 1. Tamoxifen (Sigma-Aldrich) was injected intraperitoneally at postnatal day (P)2 at 0.20 mg/g bodyweight. EdU (Click-iT EdU Imaging Kit; Invitrogen) was injected intraperitoneally from P3 to P5 once a day at a dose of 50 μg/g. DT (List Biological Laboratories) was injected intraperitoneally at 12.5 ng/g, 25 ng/g, or 37.5 ng/g at P2. …

    Product #150 – Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae

Autoantibodies against NMDA receptor 1 modify rather than cause encephalitis

Wilke, JBH;Hindermann, M;Berghoff, SA;Zihsler, S;Arinrad, S;Ronnenberg, A;Barnkothe, N;Steixner-Kumar, AA;Röglin, S;Stöcker, W;Hollmann, M;Nave, KA;Lühder, F;Ehrenreich, H;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

  • Immunization of the replication cohorts followed the protocol of Wagnon et al. [17].

    Male C57B/6 J mice were immunized at 8–9 weeks of age with either GluN1168-187 (control peptide), GluN1359-378 (active peptide) or for our additional comparison with ovalbumin, each emulsified in an equal volume of CFA (as described above). Antigens (200 µg) were equally distributed over 4 subcutaneous injections, 2 at shoulders and 2 at hind limbs. In addition, mice received 2 intraperitoneal injections of 200 ng of Bordetella pertussis toxin (#180, List Biological Laboratories) in PBS, immediately after and 48 h after immunization.

    Product #180 – Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Constipation induced gut microbiota dysbiosis exacerbates experimental autoimmune encephalomyelitis in C57BL/6 mice

Lin, X;Liu, Y;Ma, L;Ma, X;Shen, L;Ma, X;Chen, Z;Chen, H;Li, D;Su, Z;Chen, X;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

The differentiation status of hair cells that regenerate naturally in the vestibular inner ear of the adult mouse

González-Garrido, A;Pujol, R;Ramírez, OL;Finkbeiner, C;Eatock, RA;Stone, JS;

Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae

Product: LIST™ HPT™ from Escherichia coli O113

  • Study Design

    This single-center, randomized, double-blind, placebo-controlled, full-factorial single-dose study was conducted between December 2016 and December 2017 in subjects in whom pyrexia was induced by intravenous (IV) administration of a reference standard endotoxin (RSE; identifier: NCT02761980). In this standardized model, fever was induced by endotoxin (gram-negative bacterial lipopolysaccharide) derived from Escherichia coli O113, which was developed as a national biological reference standard in 1976 by the National Institute of Allergy and Infectious Diseases and the US Food and Drug Administration.17 The RSE used in this study was a new lot supplied by List Biological Laboratories, Inc. (Campbell, California). …

    Product #433 – LIST™ HPT™ from Escherichia coli O113

A direct comparison of afferents to the rat anterior thalamic nuclei and nucleus reuniens: overlapping but different

Mathiasen, ML;Nelson, AJD;Amin, E;O'Mara, SM;Aggleton, JP;

Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

Selenium Modulates the Allergic Response to Whey Protein in a Mouse Model for Cows Milk Allergy

Zhao, X;Thijssen, S;Chen, H;Garssen, J;Knippels, L;Hogenkamp, A;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

  • 2.2. Experimental Design

    … In the sensitization phase (day 0–28), mice in the PBS group were administered 10 µg of cholera toxin as an adjuvant (CT; List Biological Laboratories, Campbell, CA, USA) in 0.5 mL PBS via oral gavage. Mice in the other experimental groups were administered 20 mg whey together with 10 μg CT/0.5 mL PBS. …

    Product #100B – Cholera Toxin (AZIDE-FREE) from Vibrio cholerae