#122 (0.5 mg)
$600.00
#123 (0.25 mg)
$545.00
Enterotoxin B (SEB) is an extracellular toxin produced by certain strains of Staphylococcus aureus. SEB is synthesized as a precursor protein of 266 amino acids. This precursor is then activated during excretion of the protein by cleavage of an N-terminal portion of the molecule. The active enterotoxin B is a single 239 amino acid chain of molecular weight 28 kDa and isoelectric point of 8.
Staphylococcus aureus enterotoxins are responsible for many cases of food poisoning and toxic shock syndrome and have been implicated in rheumatoid arthritis, an autoimmune disease. SEB is a “superantigen” that binds to major histocompatibility complex (MHC) class II molecules. This activity elicits cytokine gene expression, phospholipase C activation, T-cell stimulation and serotonin release from mast cells from the host immune system. Enterotoxin B is also a strong mitogen, inducing DNA and interferon synthesis in lymphocytes.
SEB is a useful reagent for the production of cytokines in animals and cell culture. We are learning that cytokine production is of great importance in the progression of certain disease. Models of cytokine production in cells and animals serve to identify therapies which may control this aspect of infection.
SEB preparations from List Labs are highly purified by ion exchange chromatography from Staphylococcus aureus strain S6.
Enterotoxin Type B Toxoid from Staphylococcus aureus (SEB Toxoid) is produced from purified SEB which has been inactivated with formaldehyde. SEB Toxoid has been used to vaccinate monkeys by aerosol immunization.
Journal For Immunotherapy Of Cancer
Chaudhary, O;Trotta, D;Wang, K;Wang, X;Chu, X;Bradley, C;Okulicz, J;Maves, RC;Kronmann, K;Schofield, CM;Blaylock, JM;Deng, Y;Schalper, KA;Kaech, SM;Agan, B;Ganesan, A;Emu, B;
Product: Enterotoxin Type B from Staphylococcus aureus
Immunity
Collora, JA;Liu, R;Pinto-Santini, D;Ravindra, N;Ganoza, C;Lama, JR;Alfaro, R;Chiarella, J;Spudich, S;Mounzer, K;Tebas, P;Montaner, LJ;van Dijk, D;Duerr, A;Ho, YC;
Product: Enterotoxin Type B from Staphylococcus aureus
Iscience
McDavid, A;Laniewski, N;Grier, A;Gill, A;Kessler, H;Huyck, H;Carbonell, E;Holden-Wiltse, J;Bandyopadhyay, S;Carnahan, J;Dylag, A;Topham, D;Falsey, A;Caserta, M;Pryhuber, G;Gill, S;Scheible, K;
Product: Enterotoxin Type B from Staphylococcus aureus
Molecular Therapy - Methods & Clinical Development
Wang, L;Warzecha, C;Kistner, A;Chichester, J;Bell, P;Buza, E;He, Z;Pampena, M;Couthouis, J;Sethi, S;McKeever, K;Betts, M;Kakkis, E;Wilson, J;Wadsworth, S;Sullivan, B;
Product: Enterotoxin Type B from Staphylococcus aureus
Cell Host & Microbe
Zabaleta, N;Dai, W;Bhatt, U;Hérate, C;Maisonnasse, P;Chichester, JA;Sanmiguel, J;Estelien, R;Michalson, KT;Diop, C;Maciorowski, D;Dereuddre-Bosquet, N;Cavarelli, M;Gallouët, AS;Naninck, T;Kahlaoui, N;Lemaitre, J;Qi, W;Hudspeth, E;Cucalon, A;Dyer, CD;Pampena, MB;Knox, JJ;LaRocque, RC;Charles, RC;Li, D;Kim, M;Sheridan, A;Storm, N;Johnson, RI;Feldman, J;Hauser, BM;Contreras, V;Marlin, R;Tsong Fang, RH;Chapon, C;van der Werf, S;Zinn, E;Ryan, A;Kobayashi, DT;Chauhan, R;McGlynn, M;Ryan, ET;Schmidt, AG;Price, B;Honko, A;Griffiths, A;Yaghmour, S;Hodge, R;Betts, MR;Freeman, MW;Wilson, JM;Le Grand, R;Vandenberghe, LH;
Product: Enterotoxin Type B from Staphylococcus aureus
Plos Pathogens
Rinaldi, S;de Armas, L;Dominguez-Rodríguez, S;Pallikkuth, S;Dinh, V;Pan, L;G?rtner, K;Pahwa, R;Cotugno, N;Rojo, P;Nastouli, E;Klein, N;Foster, C;De Rossi, A;Giaquinto, C;Rossi, P;Palma, P;EPIICAL consortium, ;
Product: Enterotoxin Type B from Staphylococcus aureus
High-Throughput Screening For Drug Discovery
Liu, Z;Gomez-Donart, A;Weldon, C;Senutovitch, N;ORourke, J;
Product: Enterotoxin Type B from Staphylococcus aureus
JCI Insight
Yu, KK;Fischinger, S;Smith, MT;Atyeo, C;Cizmeci, D;Wolf, CR;Layton, ED;Logue, JK;Aguilar, MS;Shuey, K;Loos, C;Yu, J;Franko, NM;Choi, RY;Wald, A;Barouch, DH;Koelle, DM;Lauffenburger, D;Chu, HY;Alter, G;Seshadri, C;
Product: Enterotoxin Type B from Staphylococcus aureus
Scientific Reports
Wee, JH;Ko, YK;Khalmuratova, R;Shin, HW;Kim, DW;Rhee, CS;
Product: Enterotoxin Type B from Staphylococcus aureus
Biorxiv : The Preprint Server For Biology
Zabaleta, N;Dai, W;Bhatt, U;Chichester, JA;Estelien, R;Sanmiguel, J;Michalson, KT;Diop, C;Maciorowski, D;Qi, W;Hudspeth, E;Cucalon, A;Dyer, CD;Pampena, MB;Knox, JJ;LaRocque, RC;Charles, RC;Li, D;Kim, M;Sheridan, A;Storm, N;Johnson, RI;Feldman, J;Hauser, BM;Ryan, A;Kobayashi, DT;Chauhan, R;McGlynn, M;Ryan, ET;Schmidt, AG;Price, B;Honko, A;Griffiths, A;Yaghmour, S;Hodge, R;Betts, MR;Freeman, MW;Wilson, JM;Vandenberghe, LH;
Product: Enterotoxin Type B from Staphylococcus aureus
Transfusion
Coombs, J;Ben Hassen, L;Leclerc, M;Tamagne, M;Pannetier, L;Khelfa, M;Delorme, A;Bocquet, T;Maury, S;Pirenne, F;Ansart-Pirenne, H;Vingert, B;
Product: Enterotoxin Type B from Staphylococcus aureus
Elife
Pallikkuth, S;Chaudhury, S;Lu, P;Pan, L;Jongert, E;Wille-Reece, U;Pahwa, S;
Product: Enterotoxin Type B from Staphylococcus aureus
Nature Medicine
Harper, J;Gordon, S;Chan, C;Wang, H;Lindemuth, E;Galardi, C;Falcinelli, S;Raines, S;Read, J;Nguyen, K;McGary, C;Nekorchuk, M;Busman-Sahay, K;Schawalder, J;King, C;Pino, M;Micci, L;Cervasi, B;Jean, S;Sanderson, A;Johns, B;Koblansky, A;Amrine-Madsen, H;Lifs
Product: Enterotoxin Type B from Staphylococcus aureus
Journal Of Controlled Release : Official Journal Of The Controlled Release Society
Kim, Y;Hwang, S;Khalmuratova, R;Kang, S;Lee, M;Song, Y;Park, JW;Yu, J;Shin, HW;Lee, Y;
Product: Enterotoxin Type B from Staphylococcus aureus
International Forum Of Allergy & Rhinology
Kong, IG;Kim, DK;Eun, KM;Yang, SK;Kim, M;Oh, H;Kim, DW;
Product: Enterotoxin Type B from Staphylococcus aureus
Aids Research And Human Retroviruses
De Armas, L;Pallikkuth, S;Rinaldi, S;Pahwa, R;Pahwa, S;
Product: Enterotoxin Type B from Staphylococcus aureus
Mucosal Immunology
Veenbergen, S;Li, P;Raatgeep, HC;Lindenbergh-Kortleve, DJ;Simons-Oosterhuis, Y;Farrel, A;Costes, LMM;Joosse, ME;van Berkel, LA;de Ruiter, LF;van Leeuwen, MA;Winter, D;Holland, SM;Freeman, AF;Wakabayashi, Y;Zhu, J;de Ridder, L;Driessen, GJ;Escher, JC;Leona
Product: Enterotoxin Type B from Staphylococcus aureus
Scientific Reports
Park, J;Wang, Q;Wu, Q;Mao-Draayer, Y;Kim, CH;
Product: Enterotoxin Type B from Staphylococcus aureus
Plos Biology
Pallikkuth, S;de Armas, LR;Rinaldi, S;George, VK;Pan, L;Arheart, KL;Pahwa, R;Pahwa, S;
Product: Enterotoxin Type B from Staphylococcus aureus
Elife
Spolski, R;West, EE;Li, P;Veenbergen, S;Yung, S;Kazemian, M;Oh, J;Yu, ZX;Freeman, AF;Holland, SM;Murphy, PM;Leonard, WJ;
Product: Enterotoxin Type B from Staphylococcus aureus
Journal For Immunotherapy Of Cancer
Fromm, G;de Silva, S;Johannes, K;Patel, A;Hornblower, JC;Schreiber, TH;
Product: Enterotoxin Type B from Staphylococcus aureus
Nature Communications
Akiyama, H;Miller, CM;Ettinger, CR;Belkina, AC;Snyder-Cappione, JE;Gummuluru, S;
Product: Enterotoxin Type B from Staphylococcus aureus
Allergy
Rouyar, A;Classe, M;Gorski, R;Bock, MD;le-Guern, J;Roche, S;Fourgous, V;Remaury, A;Paul, P;Ponsolles, C;Franon, D;Rocheteau-Beaujouan, L;Clment, M;Haddad, EB;Guillemot, JC;Didier, M;Biton, B;Orsini, C;Mikol, V;Leonetti, M;
Product: Enterotoxin Type B from Staphylococcus aureus
The Journal Of Experimental Medicine
Pardi, N;Hogan, MJ;Naradikian, MS;Parkhouse, K;Cain, DW;Jones, L;Moody, MA;Verkerke, HP;Myles, A;Willis, E;LaBranche, CC;Montefiori, DC;Lobby, JL;Saunders, KO;Liao, HX;Korber, BT;Sutherland, LL;Scearce, RM;Hraber, PT;Tombcz, I;Muramatsu, H;Ni, H;Balikov
Product: Enterotoxin Type B from Staphylococcus aureus
Scientific Reports
Lee, M;Park, CG;Huh, BK;Kim, SN;Lee, SH;Khalmuratova, R;Park, JW;Shin, HW;Choy, YB;
Product: Enterotoxin Type B from Staphylococcus aureus
Plos Pathogens
Roberts, ER;Carnathan, DG;Li, H;Shaw, GM;Silvestri, G;Betts, MR;
Product: Enterotoxin Type B from Staphylococcus aureus
Thesis
Santana, MAD;
Product: Enterotoxin Type B from Staphylococcus aureus
Laryngoscope
Kim, DW;Eun, KM;Jin, HR;Cho, SH;Kim, DK;
Product: Enterotoxin Type B from Staphylococcus aureus
Vaccine
Tung, FY;Tung, JK;Pallikkuth, S;Pahwa, S;Fischl, MA;
Product: Enterotoxin Type B from Staphylococcus aureus
Allergologia et Immunopathologia
Khalmuratova, R;Lee, M;Kim, DW;Park, JW;Shin, HW;
Product: Enterotoxin Type B from Staphylococcus aureus
Journal of Allergy and Clinical Immunology
Lee, M;Kim, DW;Yoon, H;So, D;Khalmuratova, R;Rhee, CS;Park, JW;Shin, HW;
Product: Enterotoxin Type B from Staphylococcus aureus
Nature Communications
Herter, JM;Grabie, N;Cullere, X;Azcutia, V;Rosetti, F;Bennett, P;Herter-Sprie, GS;Elyaman, W;Luscinskas, FW;Lichtman, AH;Mayadas, TN;
Product: Enterotoxin Type B from Staphylococcus aureus
Cytotherapy
Hashimoto, H;Kitano, S;Yamagata, S;Miyagi Maeshima, A;Ueda, R;Ito, A;Tada, K;Fuji, S;Yamashita, T;Tomura, D;Nukaya, I;Mineno, J;Fukuda, T;Mori, S;Takaue, Y;Heike, Y;
Product: Enterotoxin Type B from Staphylococcus aureus
PNAS
Bialas, KM;Tanaka, T;Tran, D;Varner, V;Cisneros De La Rosa, E;Chiuppesi, F;Wussow, F;Kattenhorn, L;Macri, S;Kunz, EL;Estroff, JA;Kirchherr, J;Yue, Y;Fan, Q;Lauck, M;O'Connor, DH;Hall, AH;Xavier, A;Diamond, DJ;Barry, PA;Kaur, A;Permar, SR;
Product: Enterotoxin Type B from Staphylococcus aureus
Journal of Virology
Johnson, S;Eller, M;Teigler, JE;Maloveste, SM;Schultz, BT;Soghoian, DZ;Lu, R;Oster, AF;Chenine, AL;Alter, G;Dittmer, U;Marovich, M;Robb, ML;Michael, NL;Bolton, D;Streeck, H;
Product: Enterotoxin Type B from Staphylococcus aureus
Journal of Allergy and Clinical Immunology
Shin, HW;Kim, DK;Park, MH;Eun, KM;Lee, M;So, D;Kong, IG;Mo, JH;Yang, MS;Jin, HR;Park, JW;Kim, DW;
Product: Enterotoxin Type B from Staphylococcus aureus
Journal Of Molecular Recognition
Kogot, JM;Pennington, JM;Sarkes, DA;Kingery, DA;Pellegrino, PM;Stratis-Cullum, DN;
Product: Enterotoxin Type B from Staphylococcus aureus
Laryngoscope
Jin, J;Chang, DY;Kim, SH;Rha, KS;Mo, JH;Shin, EC;Kim, YM;
Product: Enterotoxin Type B from Staphylococcus aureus
European Archives Of Oto-Rhino-Laryngology
Jin, J;Yoon, YH;Kwak, SY;Rha, KS;Kim, YM;
Product: Enterotoxin Type B from Staphylococcus aureus
Clinical Biochemistry
Kim, YM;Jin, J;Choi, JA;Cho, SN;Lim, YJ;Lee, JH;Seo, JY;Chen, HY;Rha, KS;Song, CH;
Product: Enterotoxin Type B from Staphylococcus aureus
European Archives Of Oto-Rhino-Laryngology
Jin, J;Rha, KS;Kim, DW;Kim, YM;
Product: Enterotoxin Type B from Staphylococcus aureus
Antimicrobial Agents And Chemotherapy
Jekle, A;Yoon, J;Zuck, M;Najafi, R;Wang, L;Shiau, T;Francavilla, C;Rani, SA;Eitzinger, C;Nagl, M;Anderson, M;Debabov, D;
Product: Enterotoxin Type B from Staphylococcus aureus