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Tear duct M cells exacerbate allergic conjunctivitis by facilitating germinal-center reactions
Mucosal Immunology
Oya, Y;Kimura, S;Uemura, M;Fujimura, Y;Hase, K;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
The ocular mucosal surface regularly encounters external materials in the air and tear fluids. Micro....
Widespread innervation of motoneurons by spinal V3 neurons globally amplifies locomotor output in mice
Cell Reports
Zhang, H;Deska-Gauthier, D;MacKay, CS;Hari, K;Lucas-Osma, AM;Borowska-Fielding, J;Letawsky, RL;Rancic, V;Akay, T;Fenrich, KK;Bennett, DJ;Zhang, Y;
Product: Anti-Cholera Toxin B Subunit (Goat)
While considerable progress has been made in understanding the neuronal circuits that underlie the p....
One-Step Evaluation of Doxorubicin Toxicity Through Concentration Gradient Generator Integrating Breast Cancer-on-a-Chip
Biochip Journal
Park, B;Song, Y;Youn, D;Aliya, S;Jung, E;Huh, Y;Kang, S;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Conventional drug screening platforms face limitations such as single cell line analysis, slow proce....
Elaborating the connections of a closed-loop forebrain circuit in the rat: Circumscribed evidence for novel topography within a cortico-striato-pallidal triple descending projection, with thalamic feedback, to the anterior lateral hypothalamic area
Biorxiv : The Preprint Server For Biology
Negishi, K;Navarro, VI;Montes, LP;Arzate, LS;Guerra Ruiz, JM;Sotelo, D;Toccoli, AR;Khan, AM;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
Motivated behaviors are regulated by distributed forebrain networks. Traditional approaches have oft....
Conditioning electrical stimulation enhances functional rewiring in a mouse model of nerve transfer to treat chronic spinal cord injury
Biorxiv
Jara, J;Soliman, M;Bernstein, A;Grazia, P;Ferguson, A;Brown, J;Torres?Espín, A;Hollis, E;
Product: Anti-Cholera Toxin B Subunit (Goat)
Nerve transfer surgery is a state-of-the-art surgical approach to restore hand and arm function in i....
Encoding of cerebellar dentate neuron activity during visual attention in rhesus macaques
Elife
Flierman, NA;Koay, SA;van Hoogstraten, WS;Ruigrok, TJH;Roelfsema, P;Badura, A;De Zeeuw, CI;
Product: Anti-Cholera Toxin B Subunit (Goat)
The role of cerebellum in controlling eye movements is well established, but its contribution to mor....
Dorsal raphe nucleus receives retinal projections of morphologically distinct fibers in the common marmoset (Callithrix jacchus): A subunit B cholera labeling
Journal Of Anatomy
Santana, NNM;Escarião, WKM;Silva, EHA;Fiuza, FP;Nascimento Júnior, ES;Costa, MSMO;Engelberth, RC;Cavalcante, JS;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
Non-image forming (NIF) pathways, a specialized branch of retinal circuitry, play a crucial role sup....
Allergic Reactivity and Memory Occur Independently of Sequential Switching Through IgG1
Allergy
Koenig, JFE;Wade-Vallance, AK;Jiménez-Saiz, R;Bruton, K;Gadkar, S;Grydziuszko, E;Walker, TD;Gordon, ME;Gillgrass, AE;Taylor, JJ;Waserman, S;Jordana, M;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Allergic reactions to foods are primarily driven by allergen-binding immunoglobulin (Ig)E antibodies....
Maternally activated connections of the ventral lateral septum reveal input from the posterior intralaminar thalamus
Brain Structure & Function
Puska, G;Szendi, V;Egyed, M;Dimén, D;Cservenák, M;Dobolyi, Á;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
The lateral septum (LS) demonstrates activation in response to pup exposure in mothers, and its lesi....
Senolytic Targeting of Anti-Apoptotic Bcl Family Increases Cell Death in UV-Irradiated Senescent Melanocytes: Search for Senolytics
Experimental Dermatology
Kim, JC;Kim, NY;Kim, Y;Baek, DJ;Park, TJ;Kang, HY;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Senescent melanocytes have been suggested to play a role in the development of ageing-associated pig....
Inhibition of CFTR-mediated intestinal chloride secretion by nornidulin: Cellular mechanisms and anti-secretory efficacy in human intestinal epithelial cells and human colonoids
Plos One
Yibcharoenporn, C;Kongkaew, T;Worakajit, N;Khumjiang, R;Saetang, P;Satitsri, S;Rukachaisirikul, V;Muanprasat, C;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Secretory diarrhea, a major global health concern, particularly among young children, is often chara....
Identification of antigen-presenting cell-T cell interactions driving immune responses to food
Science
Canesso, MCC;Castro, TBR;Nakandakari-Higa, S;Lockhart, A;Luehr, J;Bortolatto, J;Parsa, R;Esterházy, D;Lyu, M;Liu, TT;Murphy, KM;Sonnenberg, GF;Reis, BS;Victora, GD;Mucida, D;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
The intestinal immune system must concomitantly tolerate food and commensals and protect against pat....
Glycolytic metabolism modulation on spinal neuroinflammation and vital functions following cervical spinal cord injury
Respiratory Physiology & Neurobiology
Michel-Flutot, P;Mansart, A;Vinit, S;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
High spinal cord injuries (SCIs) often result in persistent diaphragm paralysis and respiratory dysf....
Central amygdala-to-pre-Bötzinger complex neurotransmission is direct and inhibitory
The European Journal Of Neuroscience
Gu, J;Sugimura, YK;Kato, F;Del Negro, CA;
Product: Anti-Cholera Toxin B Subunit (Goat)
Breathing behaviour is subject to emotional regulation, but the underlying mechanisms remain unclear....
RSV Vaccine with Nanoparticle-Based Poly-Sorbitol Transporter (PST) Adjuvant Improves Respiratory Protection Against RSV Through Inducing Both Systemic and Mucosal Humoral Immunity
Vaccines
Jung, SM;Kim, SJ;Park, YC;Seo, ES;Kim, CG;Kim, T;Lee, S;Cho, E;Chang, J;Yun, CH;Shim, BS;Cheon, IS;Son, YM;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Background/Objectives: Respiratory syncytial virus (RSV) causes symptoms similar to a mild cold for ....
Nuclear Focal Adhesion Kinase Protects Against Cisplatin Stress in Ovarian Carcinoma
Cancer Research Communications
Zhang, Y;Ojalill, M;Boyer, A;Chen, XL;Tahon, E;Thivolle Lioux, G;Xia, M;Abbas, M;Soylu, HM;Flieder, DB;Connolly, DC;Molinolo, AA;McHale, MT;Stupack, DG;Schlaepfer, DD;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Tumor chemotherapy resistance arises frequently and limits high grade serous ovarian cancer (HGSOC) ....
Metabolic rewiring controlled by HIF-1? tunes IgA-producing B-cell differentiation and intestinal inflammation
Cellular & Molecular Immunology
Meng, X;Asadi-Asadabad, S;Cao, S;Song, R;Lin, Z;Safhi, M;Qin, Y;Tcheumi Tactoum, E;Taudte, V;Ekici, A;Mielenz, D;Wirtz, S;Schett, G;Bozec, A;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Germinal centers where B cells undergo clonal expansion and antibody affinity maturation are hypoxic....
Dietary nucleic acids promote oral tolerance through innate sensing pathways in mice
Nature Communications
Yang, T;Li, T;Xing, Y;Cao, M;Zhang, M;Leng, Q;Qiu, J;Song, X;Chen, J;Hu, G;Qian, Y;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Oral tolerance is essential for intestinal homeostasis and systemic immune function. However, our un....
MiR-193b-365 microcluster downstream of Fezf2 coordinates neuron-subtype identity and dendritic morphology in cortical projection neurons
Iscience
Iyer, A;Vaasjo, L;Siththanandan, V;C, R;Thurmon, A;Akumuo, M;Lu, V;Nnebe, C;Nair, R;Galazo, M;Tharin, S;
Product: Cholera Toxin B Subunit (CTB) from Vibrio cholerae FITC, Conjugate
Different neuron types develop characteristic axonal and dendritic arborizations that determine thei....
Tumor-suppressive activities for pogo transposable element derived with KRAB domain via ribosome biogenesis restriction
Molecular Cell
Tu, Z;Bassal, MA;Bell, GW;Zhang, Y;Hu, Y;Quintana, LM;Gokul, D;Tenen, DG;Karnoub, AE;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Transposable elements (TEs) are indispensable for human development, with critical functions in plur....
Bioengineering Strategy to Promote CNS Nerve Growth and Regeneration via Chronic Glutamate Signaling
Acta Biomaterialia
Chang, K;Wu, JG;Ma, TL;Hsu, SH;Cho, KS;Yu, Z;Lennikov, A;Ashok, A;Rajagopalan, A;Chen, MH;Su, WF;Utheim, TP;Chen, DF;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
Being part of the mature mammalian central nervous system, impairments of the retina and optic nerve....
Axon-specific microtubule regulation drives asymmetric regeneration of sensory neuron axons
Biorxiv
Costa, A;Murillo, B;Bessa, R;Ribeiro, R;da Silva, T;Porfírio-Rodrigues, P;Martins, G;Brites, P;Kneussel, M;Misgeld, T;Brill, M;Sousa, M;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
Sensory dorsal root ganglion (DRG) neurons have a unique pseudo-unipolar morphology in which a stem ....
Topographic organization of bidirectional connections between the cingulate region (infralimbic area and anterior cingulate area, dorsal part) and the interbrain (diencephalon) of the adult male rat
Biorxiv
Negishi, K;Montes, L;Navarro, V;Soto Arzate, L;Oliveros, C;Khan, A;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
The medial prefrontal cortex [cingulate region (Brodmann, 1909)(CNG)] in the rat is a connectionally....
Label-Free Exosome Analysis by Surface-Enhanced Raman Scattering Spectroscopy with Laser-Ablated Silver Nanoparticle Substrate
Advanced Healthcare Materials
Park, JE;Nam, H;Hwang, JS;Kim, S;Kim, SJ;Kim, S;Jeon, JS;Yang, M;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Early diagnostics of breast cancer is crucial to reduce the risk of cancer metastasis and late relap....
Calbindin and Girk2/Aldh1a1 define resilient vs vulnerable dopaminergic neurons in a primate Parkinson’s disease model
Npj Parkinson'S Disease
Del Rey, NL;Hernández-Pinedo, N;Carrillo, M;Del Cerro, M;Esteban-García, N;Trigo-Damas, I;Monje, MHG;Lanciego, JL;Cavada, C;Obeso, JA;Blesa, J;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
The differential vulnerability of dopaminergic neurons of the substantia nigra pars compacta (SNc) i....
A population of Insula neurons encodes for social preference only after acute social isolation in mice
Nature Communications
Glangetas, C;Guillaumin, A;Ladevèze, E;Braine, A;Gauthier, M;Bonamy, L;Doudnikoff, E;Dhellemmes, T;Landry, M;Bézard, E;Caille, S;Taupignon, A;Baufreton, J;Georges, F;
Product: Anti-Cholera Toxin B Subunit (Goat)
The Insula functions as a multisensory relay involved in socio-emotional processing with projections....
Convergent direct and indirect cortical streams shape avoidance decisions in mice via the midline thalamus
Nature Communications
Ma, J;O'Malley, JJ;Kreiker, M;Leng, Y;Khan, I;Kindel, M;Penzo, MA;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
Current concepts of corticothalamic organization in the mammalian brain are mainly based on sensory ....
A mucosal vaccine formulation against tuberculosis by exploiting the adjuvant activity of S100A4-A damage-associated molecular pattern molecule
Vaccine
Abil, OZ;Liu, S;Yeh, YW;Wu, Y;Sen Chaudhuri, A;Li, NS;Deng, C;Xiang, Z;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), remains one of the top t....
Encoding of cerebellar dentate neuronal activity during visual attention in rhesus macaques
Biorxiv
Flierman, N;Koay, S;van Hoogstraten, W;Ruigrok, T;Roelfsema, P;Badura, A;De Zeeuw, C;
Product: Anti-Cholera Toxin B Subunit (Goat)
The role of cerebellum in controlling eye movements is well established, but its contribution to mor....
Viscerosensory signalling to the nucleus accumbens via the solitary tract nucleus
Journal Of Neurochemistry
McDougall, SJ;Ong, ZY;Heller, R;Horton, A;Thek, KK;Choi, EA;McNally, GP;Lawrence, AJ;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
The nucleus of the solitary tract (NTS) receives direct viscerosensory vagal afferent input that dri....
Standardizing the skin tape stripping method for sensitization and using it to create a mouse model of peanut allergy
International Journal Of Pharmaceutics
Nesovic, LD;Gonzalez Cruz, PE;Rychener, N;Wilks, LR;Singh Gill, H;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Animal models for food allergies serve as crucial tools in understanding allergy mechanisms and asse....
Merkel Cell Polyomavirus targets SET/PP2A complex to promote cellular proliferation and migration
Virology
Gupta, P;Venuti, A;Savoldy, M;Harold, A;Zito, FA;Taverniti, V;Romero-Medina, MC;Galati, L;Sirand, C;Shahzad, N;Shuda, M;Gheit, T;Accardi, R;Tommasino, M;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Merkel Cell Carcinoma (MCC) is a rare neuroendocrine skin cancer. In our previous work, we decoded g....
The Cystic Fibrosis Transmembrane Regulator Controls Tolerogenic Responses to Food Allergens in Mice and Humans
Medrxiv
Emmenegger, M;Zografou, C;Dai, Y;Hoyt, L;Gudneppanavar, R;Chincisan, A;Rehrauer, H;Noé, F;Zajac, N;Meisl, G;Schneider, M;Nguyen, H;Höpker, K;Knowles, T;Sospedra, M;Martin, R;Ring, A;Leeds, S;Eisenbarth, S;Egan, M;Bruscia, E;Aguzzi, A;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
IgE antibodies against the allergen Ara-h2 can cause life-threatening anaphylaxis upon exposure to p....
A synbiotic of Anaerostipes caccae and lactulose prevents and treats food allergy in mice
Cell Host & Microbe
Hesser, LA;Puente, AA;Arnold, J;Ionescu, E;Mirmira, A;Talasani, N;Lopez, J;Maccio-Maretto, L;Mimee, M;Nagler, CR;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Depletion of beneficial microbes by modern lifestyle factors correlates with the rising prevalence o....
Mitochondria Transplantation Promotes Corneal Epithelial Wound Healing
Investigative Ophthalmology & Visual Science
Raz, D;Ben-Yaakov, K;Levi, M;Bertolin, M;Ferrari, S;Ponzin, D;Busin, M;Leiba, H;Marcovich, AL;Eisenberg-Lerner, A;Rotfogel, Z;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
The integrity of the corneal epithelium is essential in maintaining normal corneal function. Conditi....
Populations of hindbrain glucagon-like peptide 1 (GLP1) neurons that innervate the hypothalamic PVH, thalamic PVT, or limbic forebrain BST have axon collaterals that reach all central regions innervated by GLP1 neurons
The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience
Randolph, AB;Zheng, H;Rinaman, L;
Product: Anti-Cholera Toxin B Subunit (Goat)
Neurons in the caudal nucleus of the solitary tract (cNTS) and intermediate reticular nucleus (IRt) ....
Orexin facilitates the peripheral chemoreflex via corticotropin releasing hormone neurons projecting to the nucleus of the solitary tract
The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience
Ben Musa, R;Cornelius-Green, J;Zang, H;Li, DP;Kline, DD;Hasser, EM;Cummings, KJ;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
We previously showed that orexin neurons are activated by hypoxia and facilitate the peripheral chem....
Parallel phosphoproteomics and metabolomics map the global metabolic tyrosine phosphoproteome
Biorxiv
Hillis, A;Tamir, T;Perry, G;Asara, J;Johnson, J;Yaron, T;Cantley, L;White, F;Toker, A;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Tyrosine phosphorylation of metabolic enzymes is an evolutionarily conserved post-translational modi....
Afferent projections to the Calca /CGRP-expressing parabrachial neurons in mice
Biorxiv : The Preprint Server For Biology
Korkutata, M;De Luca, R;Fitzgerald, B;Arrigoni, E;Scammell, TE;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
The parabrachial nucleus (PB), located in the dorsolateral pons, contains primarily glutamatergic ne....
Lessons learned from contamination with endotoxin originated from the supplement in the cell culture medium
Regenerative Therapy
Uehara, K;Oshiro, E;Ochiai, A;Takagi, R;Yamato, M;Kato, A;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Endotoxin is a typical pyrogen derived from the outer membrane of Gram-negative bacteria. In fabrica....
A mutation in Themis contributes to anaphylaxis severity following oral peanut challenge in CC027 mice
The Journal Of Allergy And Clinical Immunology
Risemberg, EL;Smeekens, JM;Cruz Cisneros, MC;Hampton, BK;Hock, P;Linnertz, CL;Miller, DR;Orgel, K;Shaw, GD;Manuel de Villena, FP;Burks, AW;Valdar, W;Kulis, MD;Ferris, MT;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
The development of peanut allergy is due to a combination of genetic and environmental factors, alth....
Anatomical circuits for flexible spatial mapping by single neurons in posterior parietal cortex
Biorxiv
Ahmed, B;Ko, H;Rüsseler, M;Smith, J;Krug, K;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
Primate lateral intraparietal area (LIP) is critical for cognitive processing. Its contribution to c....
Distributional coding of associative learning in discrete populations of midbrain dopamine neurons
Cell Reports
Avvisati, R;Kaufmann, AK;Young, CJ;Portlock, GE;Cancemi, S;Costa, RP;Magill, PJ;Dodson, PD;
Product: Anti-Cholera Toxin B Subunit (Goat)
Midbrain dopamine neurons are thought to play key roles in learning by conveying the difference betw....
A 3D atlas of sexually dimorphic lumbosacral motor neurons that control and integrate pelvic visceral and somatic functions in rats
Biorxiv
Fuller-Jackson, J;Yang, Z;Wiedmann, N;Watson, A;Jenkins, N;Keast, J;Osborne, P;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
The lumbosacral spinal motor system comprises somatic motor neurons (SMNs) that target striated musc....
Extracellular vesicles adhere to cells predominantly through the interaction of CD151-associated integrin heterodimers and GM1 with laminin
Biorxiv
Isogai, T;Hirosawa, K;Kanno, M;Sho, A;Kasai, R;Komura, N;Ando, H;Furukawa, K;Ohmi, Y;Furukawa, K;Yokota, Y;Suzuki, K;
Product: Cholera Toxin B Subunit Biotin Conjugate
Quantitative assessments using single-molecule imaging and super-resolution microscopy revealed that....
Galaninergic and hypercapnia-activated neuronal projections to the ventral respiratory column
Brain Structure & Function
Dereli, AS;Oh, AYS;McMullan, S;Kumar, NN;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
In mammals, the ventral respiratory column (VRC) plays a pivotal role in integrating neurochemically....
Chilean brush-tailed mouse (Octodon degus): a diurnal precocial rodent as a new model to study visual receptive field properties of superior colliculus neurons
Biorxiv
Márquez, N;Fernández-Aburto, P;Deichler, A;Perales, I;Letelier, J;Marín, G;Mpodozis, J;Pallas, S;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
Lab rodent species used to study the visual system and its development (hamsters, rats, and mice) ar....
Pathways from the superior colliculus and the nucleus of the optic tract to the posterior parietal cortex in macaque monkeys: Functional frameworks for representation updating and online movement guidance
The European Journal Of Neuroscience
Ugolini, G;Graf, W;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
The posterior parietal cortex (PPC) integrates multisensory and motor-related information for genera....
A stress sensor, IRE1a, is required for bacterialexotoxin-induced interleukin-1b production in tissue-resident macrophages
Cell Reports
Sasaki, I;Fukuda-Ohta, Y;Nakai, C;Wakaki-Nishiyama, N;Okamoto, C;Okuzaki, D;Morita, S;Kaji, S;Furuta, Y;Hemmi, H;Kato, T;Yamamoto, A;Tosuji, E;Saitoh, SI;Tanaka, T;Hoshino, K;Fukuda, S;Miyake, K;Kuroda, E;Ishii, KJ;Iwawaki, T;Furukawa, K;Kaisho, T;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
Cholera toxin (CT), a bacterial exotoxin composed of one A subunit (CTA) and five B subunits (CTB), ....
A Mucosal Vaccine Formulation Against Tuberculosis by Exploiting the Adjuvant Activity of S100a4A Damage-Associated Molecular Pattern Molecule
SSRN
Abil, O;Liu, S;Yeh, Y;WU, Y;Sen Chaudhuri, A;Shan Li, N;Deng, C;Xiang, Z;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), remains one of the top t....
A cerebro-cerebellar network for learning visuomotor associations
Nature Communications
Sendhilnathan, N;Bostan, AC;Strick, PL;Goldberg, ME;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
Consensus is rapidly building to support a role for the cerebellum beyond motor function, but its co....
Investigation of vagal sensory neurons in mice using optical vagal stimulation and tracheal neuroanatomy
Iscience
Moe, AAK;Bautista, TG;Trewella, MW;Korim, WS;Yao, ST;Behrens, R;Driessen, AK;McGovern, AE;Mazzone, SB;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
In rats and guinea pigs, sensory innervation of the airways is derived largely from the vagus nerve,....
MucoRice-CTB line 19A, a new marker-free transgenic rice-based cholera vaccine produced in an LED-based hydroponic system
Frontiers In Plant Science
Yuki, Y;Kurokawa, S;Sugiura, K;Kashima, K;Maruyama, S;Yamanoue, T;Honma, A;Mejima, M;Takeyama, N;Kuroda, M;Kozuka-Hata, H;Oyama, M;Masumura, T;Nakahashi-Ouchida, R;Fujihashi, K;Hiraizumi, T;Goto, E;Kiyono, H;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
We previously established the selection-marker-free rice-based oral cholera vaccine (MucoRice-CTB) l....
Migratory CD103+CD11b+ cDC2 cells in Peyer’s patches are critical for gut IgA responses following oral immunization
Mucosal Immunology
Gribonika, I;Strömberg, A;Chandode, RK;Schön, K;Lahl, K;Bemark, M;Lycke, N;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Induction and regulation of specific intestinal IgA responses critically depend on dendritic cell su....
Multimodal sensory control of motor performance by glycinergic interneurons of the mouse spinal cord deep dorsal horn
Neuron
Gradwell, MA;Ozeri-Engelhard, N;Eisdorfer, JT;Laflamme, OD;Gonzalez, M;Upadhyay, A;Medlock, L;Shrier, T;Patel, KR;Aoki, A;Gandhi, M;Abbas-Zadeh, G;Oputa, O;Thackray, JK;Ricci, M;George, A;Yusuf, N;Keating, J;Imtiaz, Z;Alomary, SA;Bohic, M;Haas, M;Hernandez, Y;Prescott, SA;Akay, T;Abraira, VE;
Product: Anti-Cholera Toxin B Subunit (Goat)
Sensory feedback is integral for contextually appropriate motor output, yet the neural circuits resp....
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Cellular signal transduction comprises a complex series of biochemical reactions by which extracellu....
Impact of consumption of the human milk oligosaccharides 2′-FL and LNnT on reduction of risk of allergic sensitisation
Food And Agricultural Immunology
Holvoet, S;Foata, F;Nutten, S;Ní Cléirigh, E;Shevlyakova, M;Kwong Chung, C;Lefevre, G;Sprenger, N;Bourdeau, T;Donnicola, D;Noti, M;Combremont, S;Binia, A;Nembrini, C;Vogel, M;Kiess, W;Blanchard, C;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Human Milk Oligosaccharides (HMOs) have been proposed to be instrumental in building immune competen....
The Dorsal Column Nuclei Scales Mechanical Allodynia During Neuropathic Pain
Biorxiv
Upadhyay, A;Gradwell, M;Vajtay, T;Conner, J;Sayal, A;Azadegan, C;Patel, K;Thackary, J;Bohic, M;Imai, F;Ogundare, S;Yoshida, Y;Abdus-Saboor, I;Azim, E;Abraira, V;
Product: Anti-Cholera Toxin B Subunit (Goat)
Tactile perception relies on reliable transmission and modulation of low-threshold information as it....
Aberrant axon initial segment is an indicator for task-independent neural activity in autism model mice
Biorxiv
Otani, Y;Koga, K;Kawabata, R;Liu, X;Miyajima, H;Takumi, T;Fujitani, M;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
Autism spectrum disorder (ASD) is a developmental disorder characterized by impairments in several c....
Type 2-polarized memory B cells hold allergen-specific IgE memory
Science Translational Medicine
Koenig, JFE;Knudsen, NPH;Phelps, A;Bruton, K;Hoof, I;Lund, G;Libera, DD;Lund, A;Christensen, LH;Glass, DR;Walker, TD;Fang, A;Waserman, S;Jordana, M;Andersen, PS;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Allergen-specific immunoglobulin E (IgE) antibodies mediate pathology in diseases such as allergic r....
Sustained silencing peanut allergy by xanthopurpurin is associated with suppression of peripheral and bone marrow IgE-producing B cell
Frontiers In Immunology
Yang, N;Srivastava, K;Chen, Y;Li, H;Maskey, A;Yoo, P;Liu, X;Tiwari, RK;Geliebter, J;Nowak-Wegrzyn, A;Zhan, J;Li, XM;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Peanut allergy is an immunoglobulin E (IgE) mediated food allergy. Rubia cordifolia L. (R. cordifoli....
Formation of a giant unilocular vacuole via macropinocytosis-like process confers anoikis resistance
Biorxiv
Kim, J;Kim, D;Kim, D;Lee, S;Jang, W;Lim, D;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Cell survival in metazoans depends on cell attachment to the extracellular matrix (ECM) or to neighb....
Identification of a novel perifornical-hypothalamic-area-projecting serotonergic system that inhibits innate panic and conditioned fear responses
Translational Psychiatry
Bernabe, CS;Caliman, IF;de Abreu, ARR;Molosh, AI;Truitt, WA;Shekhar, A;Johnson, PL;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
The serotonin (5-HT) system is heavily implicated in the regulation of anxiety and trauma-related di....
Thymic-Epithelial-Cell-Dependent Microenvironment Influences Proliferation and Apoptosis of Leukemic Cells
International Journal Of Molecular Sciences
Patel, S;Zhdanovskaya, N;Sergio, I;Cardinale, A;Rosichini, M;Varricchio, C;Pace, E;Capalbo, C;Locatelli, F;Macone, A;Velardi, E;Palermo, R;Felli, M;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
T-cell acute lymphoblastic leukemia (T-ALL) is a hematological cancer characterized by the infiltrat....
Disynaptic inhibitory cerebellar control over caudal medial accessory olive
Eneuro
van Hoogstraten, WS;Lute, MCC;Liu, Z;Broersen, R;Mangili, L;Kros, L;Gao, Z;Wang, X;van den Maagdenberg, AMJM;De Zeeuw, CI;
Product: Anti-Cholera Toxin B Subunit (Goat)
The olivocerebellar system, which is critical for sensorimotor performance and learning, functions t....
Cholesterol biosynthesis inhibition synergizes with AKT inhibitors in triple-negative breast cancer
Biorxiv
Hillis, A;Martin, T;Manchester, H;Hogstrom, J;Zhang, N;Lecky, E;Kozlova, N;Persky, N;Root, D;Brown, M;Cichowski, K;Elledge, S;Muranen, T;Fruman, D;Barry, S;Clohessy, J;Madsen, R;Toker, A;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Triple-negative breast cancer (TNBC) is responsible for a disproportionate number of breast cancer d....
Rapid and label-free exosome analysis by surface-enhanced Raman spectroscopy using silver nanoparticle substrate based on selective laser ablation and melting of silver nanowire
Biorxiv
Nam, H;Park, J;Hwang, J;Kim, S;Kim, S;Kim, S;Yang, M;Jeon, J;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Early diagnostics of breast cancer is crucial to reduce the risk of cancer metastasis and late relap....
PTEN inhibition promotes robust growth of bulbospinal respiratory axons and partial recovery of diaphragm function in a chronic model of cervical contusion spinal cord injury
Biorxiv : The Preprint Server For Biology
Michel-Flutot, P;Cheng, L;Thomas, SJ;Lisi, B;Schwartz, H;Lam, S;Lyttle, M;Jaffe, DA;Smith, G;Li, S;Wright, MC;Lepore, AC;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
High spinal cord injury (SCI) leads to persistent and debilitating compromise in respiratory functio....
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
?????????????????????????????????????? ?????????????????????????????????????? ??????????????????????....
Perinatal High Fat Diet Exposure Disrupts Development of Vagal Neurocircuits That Coordinate Gastric Motility
Thesis
Carson, K;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
Maternal obesity is a rapidly growing problem in the United States as only 2 out of 5 pregnant indiv....
Influence of early microbial colonisation and the I?B transcription co-factor Bcl3 on intestinal immune homeostasis
Thesis
Kohler, AC;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
* Originaltitel: Influence of early microbial colonisation and the I?B transcription co-factor Bcl3 ....
Parabrachial Neurons: Their Connections and Role in Maintaining Body Temperature, Wakefulness, and Appetite
Thesis
Grady, F;
Product: Anti-Cholera Toxin B Subunit (Goat)
Involvement of peptidergic Edinger-Westphal nucleus in the neurobiology of migraine and acute alcohol exposure
Thesis
Khalaf, AOAA;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
The main objective of this thesis was to examine the involvement of the centrally projecting Edinger....
Metabolic fitness of IgA+ plasma cells in the gut requires DOCK8
Mucosal Immunology
Zhang, B;Chen, S;Yin, X;McBride, CD;Gertie, JA;Yurieva, M;Bielecka, AA;Hoffmann, B;Travis Hinson, J;Grassmann, J;Xu, L;Siniscalco, ER;Soldatenko, A;Hoyt, L;Joseph, J;Norton, EB;Uthaman, G;Palm, NW;Liu, E;Eisenbarth, SC;Williams, A;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Dedicator of cytokinesis 8 (DOCK8) mutations lead to a primary immunodeficiency associated with recu....
Glycosylation-modified antigens as a tolerance-inducing vaccine platform prevent anaphylaxis in a pre-clinical model of food allergy
Cell Reports Medicine
Cao, S;Maulloo, CD;Raczy, MM;Sabados, M;Slezak, AJ;Nguyen, M;Solanki, A;Wallace, RP;Shim, HN;Wilson, DS;Hubbell, JA;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
The only FDA-approved oral immunotherapy for a food allergy provides protection against accidental e....
Chronic Adaptations in the Dorsal Horn following a cervical spinal cord injury in primates
The Journal Of Neuroscience
Fisher, K;Garner, J;Darian-Smith, C;
Product: Anti-Cholera Toxin B Subunit (Goat)
Spinal cord injury (SCI) is devastating, with limited treatment options and variable outcomes. Most ....
Synaptic circuits involving gastrin-releasing peptide receptor-expressing neurons in the dorsal horn of the mouse spinal cord
Frontiers In Molecular Neuroscience
Quillet, R;Gutierrez-Mecinas, M;Polgár, E;Dickie, AC;Boyle, KA;Watanabe, M;Todd, AJ;
Product: Anti-Cholera Toxin B Subunit (Goat)
The superficial dorsal horn (SDH) of the spinal cord contains a diverse array of neurons. The vast m....
The circadian clock time tunes axonal regeneration
Cell Metabolism
De Virgiliis, F;Mueller, F;Palmisano, I;Chadwick, JS;Luengo-Gutierrez, L;Giarrizzo, A;Yan, Y;Danzi, MC;Picon-Muñoz, C;Zhou, L;Kong, G;Serger, E;Hutson, TH;Maldonado-Lasuncion, I;Song, Y;Scheiermann, C;Brancaccio, M;Di Giovanni, S;
Product: Anti-Cholera Toxin B Subunit (Goat)
Nerve injuries cause permanent neurological disability due to limited axonal regeneration. Injury-de....
A brainstem circuit for phonation and volume control in mice
Nature Neuroscience
Veerakumar, A;Head, JP;Krasnow, MA;
Product: Anti-Cholera Toxin B Subunit (Goat)
Mammalian vocalizations are critical for communication and are produced through the process of phona....
SPINAL V1 INHIBITORY INTERNEURON CLADES DIFFER IN BIRTHDATE, PROJECTIONS TO MOTONEURONS AND HETEROGENEITY
Biorxiv : The Preprint Server For Biology
Worthy, AE;Anderson, JT;Lane, AR;Gomez-Perez, L;Wang, AA;Griffith, RW;Rivard, AF;Bikoff, JB;Alvarez, FJ;
Product: Anti-Cholera Toxin B Subunit (Goat)
Spinal cord interneurons play a crucial role in shaping motor output, but their precise identity and....
Region-specific response of central microglial cells to sciatic nerve demyelination through sensory and motor pathways
Histology And Histopathology
Wu, S;Su, Y;Wang, Y;Wang, J;Xu, D;Liu, Y;Yang, K;Gao, J;Cui, J;Bai, W;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
Peripheral nerve injury can cause changes in microglial cells on the spinal dorsal and ventral horns....
Tafluprost promotes axon regeneration after optic nerve crush via Zn2+-mTOR pathway
Neuropharmacology
Wu, S;Liu, C;Tang, J;Wu, C;Zhang, Q;Liu, Z;Han, J;Xue, J;Lin, J;Chen, Y;Yang, J;Zhuo, Y;Li, Y;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
Purpose To investigate whether Tafluprost could promote optic nerve regeneration in mice after optic....
Interferon restores replication fork stability and cell viability in BRCA-defective cells via ISG15
Nature Communications
Moro, RN;Biswas, U;Kharat, SS;Duzanic, FD;Das, P;Stavrou, M;Raso, MC;Freire, R;Chaudhuri, AR;Sharan, SK;Penengo, L;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
DNA replication and repair defects or genotoxic treatments trigger interferon (IFN)-mediated inflamm....
Identification of the regulatory circuit governing corneal epithelial fate determination and disease
Plos Biology
Smits, JGA;Cunha, DL;Amini, M;Bertolin, M;Laberthonnière, C;Qu, J;Owen, N;Latta, L;Seitz, B;Roux, LN;Stachon, T;Ferrari, S;Moosajee, M;Aberdam, D;Szentmary, N;van Heeringen, SJ;Zhou, H;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
The transparent corneal epithelium in the eye is maintained through the homeostasis regulated by lim....
Commensal bacteria signal through TLR5 and AhR to improve barrier integrity and prevent allergic responses to food
Cell Reports
Kemter, AM;Patry, RT;Arnold, J;Hesser, LA;Campbell, E;Ionescu, E;Mimee, M;Wang, S;Nagler, CR;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
The increasing prevalence of food allergies has been linked to reduced commensal microbial diversity....
A Mouse Model of Shrimp Allergy with Cross-Reactivity to Crab and Lobster
Methods In Molecular Biology
Smeekens, JM;Kesselring, JR;Bagley, K;Kulis, MD;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Food allergies are a growing public health problem with recent estimates of 10% of the US population....
A novel monoclonal antibody against 6-sulfo sialyl Lewis x glycans attenuates murine allergic rhinitis by suppressing Th2 immune responses
Scientific Reports
Liu, W;Xiong, W;Liu, W;Hirakawa, J;Kawashima, H;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Lymphocyte homing is mediated by the interaction between L-selectin on lymphocytes and its glycoprot....
Volitional inspiration is mediated by two independent output channels in the primary motor cortex
The Journal Of Comparative Neurology
Helou, LB;Dum, RP;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
The diaphragm is a multifunctional muscle that mediates both autonomic and volitional inspiration. I....
A mutation in Themis contributes to peanut-induced oral anaphylaxis in CC027 mice
Biorxiv : The Preprint Server For Biology
Risemberg, EL;Smeekens, JM;Cruz Cisneros, MC;Hampton, BK;Hock, P;Linnertz, CL;Miller, DR;Orgel, K;Shaw, GD;Pardo Manuel de Villena, F;Burks, AW;Valdar, W;Kulis, MD;Ferris, MT;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
The development of peanut allergy is due to a combination of genetic and environmental factors, alth....
Topical Spironolactone in the Treatment of Ocular Graft-Versus-Host Disease
Cureus
Wong, C;Yang, A;Liu, C;Watsky, M;Lu, X;Le, H;Yee, R;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Blockade of the larger renin-angiotensin-aldosterone system (RAAS) has been shown to have anti-fibro....
A Bioengineering-Regenerative Medicine Approach for Ocular Surface Reconstruction Using a Functionalized Native Cornea?Derived Bio?Scaffold
Advanced Functional Materials
Park, M;Richardson, A;Delic, N;Nguyen, K;Biazik, J;Zhang, R;Sprogyte, L;Nureen, L;Lees, J;Fajardo, A;Kunicki, U;Watson, S;Males, J;Girolamo, N;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Limbal stem cell deficiency (LSCD) is characterized by the loss of limbal epithelial stem cells (LES....
Protocol for isolating human BCAM-positive corneal progenitor cells by flow cytometry and cell sorting
Star Protocols
Sasamoto, Y;Yeung, PC;Tran, J;Frank, MH;Frank, NY;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
BCAM-positive basal limbal epithelial cells are an early transit-amplifying cell population (TAC) ca....
Sex-dependent effects of stress on insular cortex-to-nucleus accumbens synaptic plasticity
Biorxiv
Gauthier, M;Dugast, E;Lardeux, V;Letort, K;Belnoue, L;Balado, E;Solinas, M;Belujon, P;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
Stress is an important risk factor for the development of psychiatric disorders and men and women te....
Cholera intoxication of human enteroids reveals interplay between decoy and functional glycoconjugate ligands
Glycobiology
Singla, A;Boucher, A;Wallom, KL;Lebens, M;Kohler, JJ;Platt, FM;Yrlid, U;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Prior research on cholera toxin (CT) binding and intoxication has relied on human colonic- cancer-de....
New characterization and safety evaluation of human limbal stem cells used in clinical application: fidelity of mitotic process and mitotic spindle morphologies
Research Square
Marija Zekušić1 Marina Bujić Mihica1 Marija Skoko1 Kruno Vukušić2 Patrik Risteski2 Jelena Martinčić2 Iva M. Tolić2 Krešo Bendelja3 Snježana Ramić1 Tamara Dolenec1 Ivana Vrgoč Zimić1 Dominik Puljić1 Ivanka Petric Vicković1 Renata Iveković1 Ivanka Batarilo4 Uršula Prosenc Zmrzljak5 Alan Hoffmeister6 Tiha Vučemilo1
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Background Limbal stem cells(LSCs) are crucial for the regeneration of the corneal epithelium in pat....
Direct and Indirect Nociceptive Input from the Trigeminal Dorsal Horn to Pain-Modulating Neurons in the Rostral Ventromedial Medulla
The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience
De Preter, CC;Heinricher, MM;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
The brain is able to amplify or suppress nociceptive signals by means of descending projections to t....
Fucosylated glycoproteins and fucosylated glycolipids play opposing roles in cholera intoxication
Biorxiv : The Preprint Server For Biology
Ghorashi, AC;Boucher, A;Archer-Hartmann, SA;Murray, NB;Konada, RSR;Zhang, X;Xing, C;Azadi, P;Yrlid, U;Kohler, JJ;
Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae
Cholera toxin (CT) is the etiological agent of cholera. Here we report that multiple classes of fuco....
Patterns of collateralization of the raphe nuclei and nucleus incertus to the septo-hippocampal system
Àgora De Salut
Navarro Sánchez, M;Gil-Miravet, I;Montero Caballero, D;Chaima, L;Es-Safi, S;Olucha-Bordonau, F;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
The relaxin 3 (rln3), rich nucleus incertus (ni), and the serotonin (5ht), rich raphe nuclei, are mo....
Distinct roles of spinal commissural interneurons in transmission of contralateral sensory information
Current Biology
Laflamme, OD;Markin, SN;Deska-Gauthier, D;Banks, R;Zhang, Y;Danner, SM;Akay, T;
Product: Anti-Cholera Toxin B Subunit (Goat)
Crossed reflexes are mediated by commissural pathways transmitting sensory information to the contra....
Caspase-mediated LPS sensing and pyroptosis signaling in Hydra
Science Advances
Chen, S;Li, S;Chen, H;Gong, Y;Yang, D;Zhang, Y;Liu, Q;
Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt
Inflammatory caspases sensing lipopolysaccharide (LPS) to drive gasdermin (GSDM)-mediated pyroptosis....
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