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Characterizing a Silver Nanoparticle-Based Electrochemical Biosensor for Shiga Toxin Detection
ACS Omega
Patel, D;Hansen, M;Lambert, C;Hegde, S;Jayamohan, H;Gale, B;Sant, H;
Product: Shiga Toxin 1 from Escherichia coli
Shiga toxins (1, 2) regularly cause outbreaks and food recalls and pose a significant health risk to....
Shiga toxin targets the podocyte causing hemolytic uremic syndrome through endothelial complement activation
Med
Bowen, EE;Hurcombe, JA;Barrington, F;Keir, LS;Farmer, LK;Wherlock, MD;Ortiz-Sandoval, CG;Bruno, V;Bohorquez-Hernandez, A;Diatlov, D;Rostam-Shirazi, N;Wells, S;Stewart, M;Teboul, L;Lay, AC;Butler, MJ;Pope, RJP;Larkai, EMS;Morgan, BP;Moppett, J;Satchell, SC;Welsh, GI;Walker, PD;Licht, C;Saleem, MA;Coward, RJM;
Product: Shiga Toxin 2 from Escherichia coli
Shiga toxin (Stx)-producing Escherichia coli hemolytic uremic syndrome (STEC-HUS) is the leading cau....
Shiga-Toxin-Producing Strains of Escherichia coli O104:H4 and a Strain of O157:H7, Which Can Cause Human Hemolytic Uremic Syndrome, Differ in Biofilm Formation in the Presence of CO2 and in Their Ability to Grow in a Novel Cell Culture Medium
Microorganisms
Amemiya, K;Rozak, DA;Dankmeyer, JL;Dorman, WR;Marchand, C;Fetterer, DP;Worsham, PL;Purcell, BK;
Product: Shiga Toxin 2 from Escherichia coli
One pathogen that commonly causes gastrointestinal illnesses from the consumption of contaminated fo....
Apyrase decreases phage induction and Shiga toxin release from E. coli O157:H7 and has a protective effect during infection
Gut Microbes
Arvidsson, I;Tontanahal, A;Johansson, K;Kristoffersson, AC;Kellnerová, S;Berger, M;Dobrindt, U;Karpman, D;
Product: Anti-Shiga Toxin, Camelid Antibody, VHH
Shiga toxin (Stx)-producing enterohemorrhagic Escherichia coli (EHEC) cause gastrointestinal infecti....
C910 chemical compound inhibits the traffiking of several bacterial AB toxins with cross-protection against influenza virus
Iscience
Wu, Y;Mahtal, N;Paillares, E;Swistak, L;Sagadiev, S;Acharya, M;Demeret, C;Werf, SV;Guivel-Benhassine, F;Schwartz, O;Petracchini, S;Mettouchi, A;Caramelle, L;Couvineau, P;Thai, R;Barbe, P;Keck, M;Brodin, P;Machelart, A;Sencio, V;Trottein, F;Sachse, M;Chicanne, G;Payrastre, B;Ville, F;Kreis, V;Popoff, MR;Johannes, L;Cintrat, JC;Barbier, J;Gillet, D;Lemichez, E;
Product: Shiga Toxin 1 from Escherichia coli
The development of anti-infectives against a large range of AB-like toxin-producing bacteria include....
Identification of two lipid phosphatases that regulate sphingosine-1-phosphate cellular uptake and recycling
Journal Of Lipid Research
Kono, M;Hoachlander-Hobby, LE;Majumder, S;Schwartz, R;Byrnes, C;Zhu, H;Proia, RL;
Product: Shiga Toxin 2 from Escherichia coli
Sphingosine-1-phosphate (S1P) is a sphingolipid metabolite that serves as a potent extracellular sig....
Gut-Kidney Axis on Chip for Studying Effects of Antibiotics on Risk of Hemolytic Uremic Syndrome by Shiga Toxin-Producing Escherichia coli
Toxins
Lee, Y;Kim, MH;Alves, DR;Kim, S;Lee, LP;Sung, JH;Park, S;
Product: Shiga Toxin 2 from Escherichia coli
Shiga toxin-producing Escherichia coli (STEC) infects humans by colonizing the large intestine, and ....
Annexin Induces Cellular Uptake of Extracellular Vesicles and Delays Disease in Escherichia coli O157:H7 Infection
Microorganisms
Tontanahal, A;Arvidsson, I;Karpman, D;
Product: Anti-Shiga Toxin, Camelid Antibody, VHH
Enterohemorrhagic Escherichia coli secrete Shiga toxin and lead to hemolytic uremic syndrome. Patien....
Identification, Characterization, and Gene Expression Analysis of Thioester-Containing Proteins (TEPs), and the Host Response to Environmentally Evolved Bacteria in the Squid Euprymna scolopes
Thesis
Thuraisamy, T;
Product: Shiga Toxin 2 from Escherichia coli
The squid Euprymna scolopes forms a mutualistic symbiotic association with the bioluminescent marine....
A genome-wide CRISPR/Cas9 screen reveals that the aryl hydrocarbon receptor stimulates sphingolipid levels
The Journal Of Biological Chemistry
Majumder, S;Kono, M;Lee, YT;Byrnes, C;Li, C;Tuymetova, G;Proia, RL;
Product: Shiga Toxin 1 from Escherichia coli
Sphingolipid biosynthesis generates lipids for membranes and signaling that are crucial for many dev....
Revisiting Old Ionophore Lasalocid as a Novel Inhibitor of Multiple Toxins
Toxins
Mahtal, N;Wu, Y;Cintrat, JC;Barbier, J;Lemichez, E;Gillet, D;
Product: Shiga Toxin 1 from Escherichia coli
The ionophore lasalocid is widely used as a veterinary drug against coccidiosis. We found recently t....
Structure-activity relationship studies of Retro-1 analogues against Shiga toxin
Chemrxiv
Abdelkafi, H;Michau, A;Pons, V;Ngadjeua, F;Clerget, A;Ouarab, LA;Buisson, D;Caramelle, L;Gillet, D;Barbier, J;Cintrat, J;
Product: Shiga Toxin 2 from Escherichia coli
The Retro-1 molecule was identified in a high-throughput screening as an inhibitor of ricin and Shig....
Phosphorylation of IRE1 at S729 regulates RIDD in B cells and antibody production after immunization
The Journal Of Cell Biology
Tang, CA;Chang, S;Paton, AW;Paton, JC;Gabrilovich, DI;Ploegh, HL;Del Valle, JR;Hu, CA;
Product: Shiga Toxin 1 from Escherichia coli
To relieve endoplasmic reticulum (ER) stress, IRE1 splices XBP1 messenger RNA (mRNA) or engages regu....
Differential role of FL-BID and t-BID during verotoxin-1-induced apoptosis in Burkitt’s lymphoma cells
Oncogene
Debernardi, J;Hollville, E;Lipinski, M;Wiels, J;Robert, A;
Product: Shiga Toxin 1 from Escherichia coli
The globotriaosylceramide Gb3 is a glycosphingolipid expressed on a subpopulation of germinal center....
Secretion of the Shiga toxin B subunit (Stx1B) via an autotransporter protein optimizes the protective immune response to the antigen expressed in an attenuated E. coli (rEPEC E22ler) vaccine strain
Veterinary Microbiology
Byrd, W;Ruiz-Perez, F;Setty, P;Zhu, C;Boedeker, EC;
Product: Shiga Toxin 1 from Escherichia coli
We previously developed attenuated rabbit enteropathogenic E. coli (rEPEC) strains which are effecti....
A Cell-Based Fluorescent Assay to Detect the Activity of AB Toxins that Inhibit Protein Synthesis
Methods In Molecular Biology
Cherubin, P;Quiones, B;Elkahoui, S;Yokoyama, W;Teter, K;
Product: Shiga Toxin 1 from Escherichia coli
Many AB toxins elicit a cytotoxic effect involving the inhibition of protein synthesis. In this chap....
Detection of shiga toxins by lateral flow assay
Toxins
Ching, KH;He, X;Stanker, LH;Lin, AV;McGarvey, JA;Hnasko, R;
Product: Shiga Toxin 1 from Escherichia coli
Shiga toxin-producing Escherichia coli (STEC) produce shiga toxins (Stxs) that can cause human disea....
Development of an ELISA microarray assay for the sensitive and simultaneous detection of ten biodefense toxins
Analyst
Jenko, KL;Zhang, Y;Kostenko, Y;Fan, Y;Garcia-Rodriguez, C;Lou, J;Marks, JD;Varnum, SM;
Product: Shiga Toxin 1 from Escherichia coli
Plant and microbial toxins are considered bioterrorism threat agents because of their extreme toxici....
Quantitative detection of Vibrio cholera toxin by real-time and dynamic cytotoxicity monitoring
Journal Of Clinical Microbiolgy
Jin, D;Luo, Y;Zheng, M;Li, H;Zhang, J;Stampfl, M;Xu, X;Ding, G;Zhang, Y;Tang, YW;
Product: Shiga Toxin 1 from Escherichia coli
We report here the quantitative detection of Vibrio cholerae toxin (CT) in isolates and stool specim....
Mouse in vivo neutralization of Escherichia coli Shiga toxin 2 with monoclonal antibodies.
Toxins
Cheng, LW;Henderson, TD;Patfield, S;Stanker, LH;He, X;
Product: Shiga Toxin 2 from Escherichia coli
Shiga toxin-producing Escherichia coli (STEC) food contaminations pose serious health concerns, and ....
A polyclonal antibody based immunoassay detects seven subtypes of Shiga toxin 2 produced by Escherichia coli in human and environmental samples
PLoS ONE
He, X;Patfield, S;Hnasko, R;Rasooly, R;Mandrell, RE;
Product: Shiga Toxin 1 from Escherichia coli
Shiga toxin-producing Escherichia coli (STEC) are frequent causes of severe human diseases ranging f....
Increased expression of complement regulators CD55 and CD59 on peripheral blood cells in patients with EAHEC O104:H4 infection
PLoS ONE
Dammermann, W;Schipper, P;Ullrich, S;Fraedrich, K;Schulze Zur Wiesch, J;Frndt, T;Tiegs, G;Lohse, A;Lth, S;
Product: Shiga Toxin 2 from Escherichia coli
An outbreak of Shiga Toxin 2 (Stx-2) producing enterohemorrhagic and enteroaggregative E.coli (EAHEC....
Development and characterization of monoclonal antibodies against Shiga toxin 2 and their application for toxin detection in milk
Journal Of Immunological Methods
He, X;McMahon, S;Skinner, C;Merrill, P;Scotcher, MC;Stanker, LH;
Product: Shiga Toxin 1 from Escherichia coli
Human infection by Shiga toxin producing Escherichia coli (STEC) is one of the most prevalent foodbo....
Milk inhibits the biological activity of ricin
The Journal Of Biological Chemistry
Rasooly, R;He, X;Friedman, M;
Product: Shiga Toxin 2 from Escherichia coli
Ricin is a highly toxic protein produced by the castor plant Ricinus communis. The toxin is relative....
Activation of p53/ATM-dependent DNA damage signaling pathway by shiga toxin in mammalian cells
Microbial Pathogenesis
Talukder, KA;Azmi, IJ;Ahmed, KA;Hossain, MS;Kabir, Y;Cravioto, A;Sack, DA;Nur-E-Kamal, A;
Product: Shiga Toxin 1 from Escherichia coli
In this report, we studied the role of DNA damage signaling pathway in shiga toxin (STX)-induced mam....
Rapid detection of ribosome inactivating protein toxins by mass-spectrometry-based functional assays
International Journal Of Mass Spectrometry
Antoine, MD;Hagan, NA;Lin, JS;Feldman, AB;Demirev, PA;
Product: Shiga Toxin 1 from Escherichia coli
A family of structurally related protein toxins extracted from bacteria or plants have a similar mec....
Forssman Synthetase Expression Results in Diminished Shiga Toxin Susceptibility: a Role for Glycolipids in Determining Host-Microbe Interactions
Infection and Immunity
Elliott SP, Yu M, Xu H, Haslam DB
Product: Shiga Toxin 1 from Escherichia coli
Forssman glycolipid (FG), the product of Forssman synthetase (FS), is widely expressed among nonprim....
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