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#100B (1 mg)

Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

Info

APOPTOSIS PRODUCT BULLETIN
CHOLERA TOXIN PRODUCT BULLETIN
SIGNAL TRANSDUCTION PRODUCT BULLETIN
COA

Current
Certificate of Testing for Lot# 10071A2
Archived
Certificate of Testing for Lot# 10071A1
Certificate of Analysis for Lot # 10070A1
Certificate of Analysis for Lot # 10069A1
Certificate of Analysis for Lot # 10067A1
Certificate of Analysis for Lot # 10068A1
Certificate of Analysis for Lot # 10060A2
Certificate of Analysis for Lot # 10063A1
SDS

100-sdsv4-128-1-8-pdf-8
Poster

Current
HPLC Method to Assay the ADP-Ribosyltransferase Activity of Cholera Toxin

$375.00

#104 (0.5 mg)

Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

Info

FITC AND BIOTIN CONJUGATES OF CHOLERA TOXIN B SUBUNIT
CHOLERA TOXIN PRODUCT BULLETIN
COA

Current
Certificate of Testing for Lot # 10434A1
Archived
Certificate of Analysis for Lot # 10433A1
Certificate of Analysis for Lot # 10430A1
Certificate of Analysis for Lot # 10431A1
Certificate of Analysis for Lot # 10432A1
Certificate of Analysis for Lot # 10431B1
N-HAZ

non-hazardous-statement-conjugates-129-1-pdf
Poster

Current
HPLC Method to Assay the ADP-Ribosyltransferase Activity of Cholera Toxin

$600.00

#106 (0.2 mg)

Cholera Toxin B Subunit (CTB) from Vibrio cholerae FITC, Conjugate

Info

CHOLERA TOXIN PRODUCT BULLETIN
FITC AND BIOTIN CONJUGATES OF CHOLERA TOXIN B SUBUNIT
COA

Current
Certificate of Analysis for Lot # 10616A v02
Archived
Certificate of Analysis for Lot # 10616A
N-HAZ

non-hazardous-statement-conjugates-12-1-pdf

$300.00

#112 (0.2 mg)

Cholera Toxin B Subunit Biotin Conjugate

Info

CHOLERA TOXIN AND RELATED PRODUCTS
FITC AND BIOTIN CONJUGATES OF CHOLERA TOXIN B SUBUNIT
COA

Current
Certificate of Analysis for Lot # 11212A1
Archived
Certificate of Analysis for Lot # 11211A1
N-HAZ

non-hazardous-statement-conjugates-226-1-pdf

$695.00

#133L (Liquid)

Botulinum Neurotoxin Type A Toxoid from Clostridium botulinum

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 1333A7
Archived
Certificate of Analysis for Lot # 1333A1
Certificate of Analysis for Lot # 1333A3
Certificate of Analysis for Lot # 1333A4
N-HAZ

non-hazardous-statement-toxoids-28-1-pdf

#149A (0.25 mg)

Diphtheria Toxin CRM197, Mutant

Info

DIPHTHERIA TOXIN, TOXOID, CRM MUTANT PRODUCT BULLETIN
Diphtheria Toxin and Engineered Receptor
Protein Carriers for Vaccines
COA

Current
Certificate of Analysis for Lot # 14937A1
Archived
Certificate of Analysis for Lot # 14936A1
Certificate of Analysis for Lot # 14934A1
Certificate of Analysis for Lot # 14935A1
N-HAZ

non-hazardous-statement-v2

$525.00

#150 (1 mg)

Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae

Info

APOPTOSIS PRODUCT BULLETIN
DIPHTHERIA TOXIN, TOXOID, CRM MUTANT PRODUCT BULLETIN
Diphtheria Toxin and Engineered Receptor
Protein Carriers for Vaccines
COA

Current
Certificate of Testing for LoT #15048A1
Archived
Certificate of Analysis for Lot # 15047A1
Certificate of Analysis for Lot # 15046A1
Certificate of Analysis for Lot #15045A1
Certificate of Analysis for Lot # 15042B1
Certificate of Analysis for Lot # 15043A1
SDS

150-sdsv3-35-1-pdf

$783.00

#151 (0.5 mg)

Diphtheria Toxoid, from Corynebacterium diphtheriae

This product is Out of stock.

Info

DIPHTHERIA TOXIN, TOXOID, CRM MUTANT PRODUCT BULLETIN
Diphtheria Toxin and Engineered Receptor
COA

Current
Certificate of Analysis for Lot # 1519A1 v02
Archived
Certificate of Analysis for Lot # 1518A1
N-HAZ

non-hazardous-statement-toxoids-36-1-pdf

#152C (100 ug)

Toxin A from Clostridium difficile

Info

APOPTOSIS PRODUCT BULLETIN
C. DIFFICILE TOXINS PRODUCT BULLETIN
SIGNAL TRANSDUCTION PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Analysis for Lot # 15219A3 v02
Archived
Certificate of Analysis for Lot # 15219A2
Certificate of Analysis for Lot # 15215A1C
Certificate of Analysis for Lot # 15215A5
SDS

152-sdsv3-209-1-pdf

$620.00

#155L (liquid)

Toxin B from Clostridium difficile

Info

APOPTOSIS PRODUCT BULLETIN
C. DIFFICILE TOXINS PRODUCT BULLETIN
SIGNAL TRANSDUCTION PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Testing for Lot #15522A3 v01
Archived
Certificate of Testing for Lot #15522A2 v01
Certificate of Analysis for Lot # 15521G1B
Certificate of Analysis for Lot # 15521G1A
Certificate of Analysis for Lot # 15521A1
Certificate of Analysis for Lot # 15522A1
Certificate of Analysis for Lot # 15518A1A
Certificate of Analysis for Lot # 15520A3A
Certificate of Analysis for Lot # 15520A4A
Certificate of Analysis for Lot # 15520A3B
Certificate of Analysis for Lot # 15521A2
SDS

155-sdsv5-41-1-pdf

$995.00

#156 (50 ug)

Pasteurella multocida Toxin

Info

APOPTOSIS PRODUCT BULLETIN
PASTEURELLA MULTOCIDA TOXIN PRODUCT BULLETIN
SIGNAL TRANSDUCTION PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 1566C1
Archived
Certificate of Analysis for Lot # 1566A1
SDS

156-sdsv3-44-1-pdf

$555.00

#157A (20 ug)

Binary Toxin from Clostridium difficile, A Subunit

This product is discontinued.

Info

C. DIFFICILE TOXINS PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Analysis for Lot # 1573A1
N-HAZ

non-hazardous-statement-other-toxins-201-1-pdf

#159A (0.1 mg)

Glutamate Dehydrogenase (GDH) from Clostridium difficile

This product is discontinued.

Info

C. DIFFICILE TOXINS PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Analysis for Lot # 1591A2
N-HAZ

non-hazardous-statement-other-toxins-222-1-pdf

#161 (10 ug)

Shiga Toxin 1 from Escherichia coli

Info

SHIGA TOXINS Product information
COA

Current
Certificate of Analysis for Lot # 1611A1
SDS

161-sdsv3-174-1-pdf

$600.00

#162L (Liquid)

Shiga Toxin 2 from Escherichia coli

COA

Current
Certificate of Analysis for Lot # 1623A1 v05
Archived
Certificate of Analysis for Lot # 1621A1
Certificate of Analysis for Lot # 1622A1
SDS

162-162l-and-164-sdsv5-176-1-pdf

$955.00

#169L (Liquid)

Anthrax Lethal Factor (LF-A), Recombinant from B. anthracis Native Sequence

Info

MAPKKIDE PLUS PRODUCT BULLETIN
ANTHRAX TOXIN PRODUCT BULLETIN
LETHAL FACTOR, NATIVE SEQUENCE, DESCRIPTION
COA

Current
Certificate of Analysis for Lot # 1694A1
Archived
Certificate of Analysis for Lot # 1692A1B
N-HAZ

non-hazardous-statement-anthrax-toxins-03-15-18-172-1-pdf

$500.00

#170L (Liquid)

Filamentous Hemagglutinin (FHA) from Bordetella pertussis

Info

BORDETELLA VIRULENCE FACTORS PRODUCT INFORMATION
PERTUSSIS TOXIN FROM BORDETELLA PERTUSSIS PRODUCT INFORMATION
SIGNAL TRANSDUCTION PRODUCT BULLETIN
COA

Current
Certificate of Testing for Lot#17056A1
N-HAZ

non-hazardous-statement-other-toxins-158-1-pdf

$450.00

#171E (0.5 mg)

Anthrax Protective Antigen (PA), Recombinant from B. anthracis

Product # 171 is the entire 83 kDa native protein; This product contains the entire anthrax protective antigen 83 kDa native protein.

Info

MAPKKIDE PLUS PRODUCT BULLETIN
ANTHRAX TOXIN PRODUCT BULLETIN
MAPKKIDE PRODUCT BULLETIN
COA

Current
Certificate of Testing for Lot # 17121A2
Archived
Certificate of Analysis for Lot # 17121A1
Certificate of Analysis for Lot # 17120A1
Certificate of Analysis for Lot # 17119A1B
N-HAZ

non-hazardous-statement-anthrax-toxins-210-1-pdf

$770.00

#172B (1 mg), #172L (1 mg),

Anthrax Lethal Factor (LF), Recombinant from B. anthracis

Info

MAPKKIDE PLUS PRODUCT BULLETIN
ANTHRAX TOXIN PRODUCT BULLETIN
MAPKKIDE PRODUCT BULLETIN
COA

Current
172B (1 mg)
Certificate of Analysis for Lot # 1722B15A1 v03
172L (1 mg)
Certificate of Analysis for Lot # 1722B15A2 v03
Archived
172B (1 mg)
Certificate of Analysis for Lot # 1722B10B
172B (1 mg)
Certificate of Analysis for Lot # 1722B11B
172B (1 mg)
Certificate of Analysis for Lot # 17210A1B
172L (1 mg)
Certificate of Analysis for Lot # 1722B15A1
N-HAZ

non-hazardous-statement-anthrax-toxins-53-1-2-pdf-2
Poster

Current
FRET Peptide Substrates for the Botulinum Toxins Type A, B, and E and for Anthrax Lethal Factor
Physical Characteristics of rLF and rPA: Effects on Enzymatic Activity and Binding
Internally Quenched Fluorogenic Substrates for Anthrax Lethal Factor.
Sensitive Detection of Anthrax Lethal Factor in Plasma Using a Specific Biotinylated Fluorogenic Substrate
A Novel Substrate for Specific Detection of Anthrax Infection

$775.00 – $1,025.00

#173B (0.5 mg)

Anthrax Edema Factor (EF), Recombinant, Mutant S447N from B. anthracis

Info

ANTHRAX TOXIN PRODUCT BULLETIN
ADENYLATE CYCLASE TOXIN PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 1732A1
N-HAZ

non-hazardous-statement-anthrax-toxins-56-1-2-pdf-2

$980.00

#174 (0.5 mg)

Anthrax Protective Antigen, Activated (PA 63) from B. anthracis

Product # 174 is PA63, which has been created by enzymatic digestion and purified;

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 17410A1 Rev. 2021
Archived
Certificate of Analysis for Lot # 17410A1
Certificate of Analysis for Lot # 1749A1
Certificate of Analysis for Lot # 17410A1
N-HAZ

non-hazardous-statement-anthrax-toxins-57-1-pdf

$625.00

#175 (50 ug)

Anthrax PA 63 - FITC Conjugate

Product # 175 is purified PA63 conjugated to FITC for visualization.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 1752A1v02
Archived
Certificate of Analysis for Lot # 1751A
N-HAZ

non-hazardous-statement-anthrax-toxins-59-1-pdf

$475.00

#176B (1 mg),

Anthrax Lethal Factor (LF), Recombinant, Mutant E687C from B. anthracis

Info

ANTHRAX TOXIN PROTECTIVE ANTIGEN, LETHAL FACTOR, EDEMA FACTOR From Bacillus anthracis
COA

Current
Certificate of Analysis for Lot # 1761AA Size A
Certificate of Analysis for Lot # 1761AA
N-HAZ

non-hazardous-statement-anthrax-toxins-60-1-pdf

$1,050.00

#177A (50 ug), #177B (.25mg),

Anthrax Protective Antigen Fragment (PA 20) from B. anthracis

Product # 177 is PA20, the approximately 20 kDA fragment cleaved from PA; and

Info
COA

Current
Certificate of Analysis for Lot # 1771A1 v02 Size A
Certificate of Analysis for Lot # 1771A1 v02 Size B
Archived
Certificate of Analysis for Lot # 1771A1 Size A
N-HAZ

non-hazardous-statement-anthrax-toxins-62-1-pdf

$355.00 – $675.00

#178A (0.1 mg)

Anthrax Edema Factor (EF), Recombinant from B. anthracis

Info
COA

Current
Certificate of Analysis for Lot # 1785A1A v02
Archived
Certificate of Analysis for Lot # 1781A1A
Certificate of Analysis for Lot # 1784A1
N-HAZ

non-hazardous-statement-anthrax-toxins-64-1

$205.00

#179A (50 ug)

Pertussis Toxin from B. pertussis (in Glycerol)

Info

PERTUSSIS TOXIN from Bordetella pertussis
SIGNAL TRANSDUCTION product information
COA

Current
Certificate of Testing for Lot#179245A1 v.02
Archived
Certificate of Testing for Lot#179244A1 v02
Certificate of Analysis for Lot # 179227A1A
Certificate of Analysis for Lot # 179216A1A
Certificate of Analysis for Lot # 179216A2A
Certificate of Analysis for Lot # 179202A1A
SDS

179-sdsv4-157-1-pdf

$505.00

#180 (50 ug)

Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Info

PERTUSSIS TOXIN from Bordetella pertussis
SIGNAL TRANSDUCTION product information
COA

Current
Certificate of Testing for Lot # 180248A1
Archived
Certificate of Testing for Lot # 180246A1
Certificate of Testing for Lot # 180245A1
Certificate of Testing for Lot # 180244A3
Certificate of Testing for Lot # 180244A1
Certificate of Testing for Lot # 180243A2 v02
Certificate of Analysis for Lot # 180243A1
Certificate of Analysis for Lot # 180242A1 v02
Certificate of Analysis for Lot # 180241A1
Certificate of Analysis for Lot # 180232A1
Certificate of Analysis for Lot # 180235A1A
SDS

180_181-sdsv5

$500.00

#181 (50 ug)

Pertussis Toxin from B. pertussis, Lyophilized (Salt-Free)

Info

PERTUSSIS TOXIN from Bordetella pertussis
SIGNAL TRANSDUCTION product information
COA

Current
Certificate of Testing for Lot # 1812427A1
Archived
Certificate of Testing for Lot # 181242A2
Certificate of Testing for Lot # 181244A1
Certificate of Testing for Lot # 181242A1 v03
Certificate of Analysis for Lot # 181238A1
Certificate of Analysis for Lot # 181218A1
Certificate of Analysis for Lot # 181220A1
Certificate of Analysis for Lot # 181241A1
Certificate of Analysis for Lot # 181236A1
SDS

180_181-sdsv5

$510.00

#184 (50 ug)

Pertussis Toxin Mutant

This product is discontinued.

Info

PERTUSSIS TOXIN from Bordetella Pertussis
COA

Current
Certificate of Analysis for Lot # 1842A1 v02
N-HAZ

non-hazardous-statement-toxoids-202-1-pdf

#186 (50 ug)

Fimbriae 2/3 from B. pertussis

This product is discontinued.

Info

FIMBRIAE 2/3 FROM BORDETELLA PERTUSSIS
Bordetella Virulence Factors
COA

Current
Certificate of Analysis for Lot # 1865A1
Archived
Certificate of Analysis for Lot # 1863A1
Certificate of Analysis for Lot # 1864C1
N-HAZ

non-hazardous-statement-other-toxins-180-1-pdf

#187 (50 ug)

Pertactin from B. pertussis (69 kDa Protein)

This product is discontinued.

Info

Bordetella Virulence Factors
PERTUSSIS TOXIN from Bordetella pertussis
COA

Current
Certificate of Analysis for Lot # 1876A1 v02
Archived
Certificate of Analysis for Lot # 1874A1
Certificate of Analysis for Lot # 1873A1
Certificate of Analysis for Lot # 1872A1
N-HAZ

non-hazardous-statement-other-toxins-192-1-pdf

#188L (Liquid)

Adenylate Cyclase Toxin, Recombinant from B. pertussis

Info

BORDETELLA VIRULENCE FACTORS PRODUCT INFORMATION
PERTUSSIS TOXIN FROM BORDETELLA PERTUSSIS PRODUCT INFORMATION
ADENYLATE CYCLASE TOXIN PRODUCT BULLETIN
SIGNAL TRANSDUCTION PRODUCT BULLETIN
GENETIC DESCRIPTION
TIPS FOR WORKING WITH ADENYLATE CYCLASE
Adenylate cyclase from B. pertussis, product comparison
COA

Current
Certificate of Testing for Lot # 18810A3
Archived
Certificate of Testing for Lot # 18810A2
Certificate of Analysis for Lot # 18810A1
Certificate of Analysis for Lot # 1889A1
Certificate of Analysis for Lot # 1888A2
Certificate of Analysis for Lot # 1888A3
Certificate of Analysis for Lot # 188L.001
N-HAZ

non-hazardous-statement-other-toxins-158-1-pdf

$505.00

#190A (25 ug), #190B (100 ug),

Tetanus Toxin from Clostridium tetani

Info

TETANUS TOXIN, TETANUS TOXOID, TETANUS LIGHT CHAIN, C-FRAGMENT, FITC C-FRAGMENT AND GST SYNAPTOBREVIN 2 PRODUCT BULLETIN
Protein Carriers for Vaccines
COA

Current
Certificate of Testing for Lot #19050A3
Certificate of Testing for Lot #19050A4
Archived
Certificate of Testing for Lot #19050A3 v02
Certificate of Analysis for Lot # 19050A2
Certificate of Analysis for Lot # 19050A1
Certificate of Analysis for Lot # 19042E1A
Certificate of Analysis for Lot # 19047B1
Certificate of Analysis for Lot # 19042C1
Certificate of Analysis for Lot # 19047A1
SDS

190-sdsv6-73-1-pdf

$300.00 – $870.00

#191A (25 ug), #191B (100 ug),

Tetanus Toxoid from Clostridium tetani

Info

TETANUS TOXIN, TETANUS TOXOID, TETANUS LIGHT CHAIN, C-FRAGMENT, FITC C-FRAGMENT AND GST SYNAPTOBREVIN 2
COA

Current
Certificate of Testing for Lot #19133A5
Certificate of Testing for Lot #19133A3
Certificate of Testing for Lot #19133A4
Archived
Certificate of Testing for Lot # 19133A2
Certificate of Testing for Lot # 19132A2
Certificate of Testing for Lot # 19131A2
Certificate of Testing for Lot # 19132A1 v02
Certificate of Analysis for Lot # 19130A1
Certificate of Analysis for Lot # 19131A1
Certificate of Analysis for Lot # 19127A1
Certificate of Analysis for Lot # 19120A1A
Certificate of Analysis for Lot # 19121A1A
Certificate of Analysis for Lot # 19122A1A
Certificate of Analysis for Lot # 19119A2
Certificate of Analysis for Lot # 19120A1B
Certificate of Analysis for Lot # 19121A1B
Certificate of Analysis for Lot # 19123A1
N-HAZ

non-hazardous-statement-toxoids-75-1-pdf

$460.00 – $1,315.00

#193 (10 ug)

Tetanus Toxin C-Fragment from Clostridium tetani

Info

TETANUS TOXIN, TETANUS TOXOID, TETANUS LIGHT CHAIN, C-FRAGMENT, FITC C-FRAGMENT AND GST SYNAPTOBREVIN 2
COA

Current
Certificate of Analysis for Lot # 19313C1
N-HAZ

non-hazardous-statement-conjugates-77-1-pdf

$750.00

#196A (10 ug)

Tetanus Toxin C-Fragment from Clostridium tetani, FITC Conjugate

This product is discontinued.

COA

Current
Certificate of Analysis for Lot # 1963A1
N-HAZ

non-hazardous-statement-conjugates-78-1-pdf

#201 (5 mg)

LPS from Escherichia coli O111:B4

Info

APOPTOSIS PRODUCT BULLETIN
HIGHLY PURIFIED BACTERIAL LPS PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 20148A1, V2
Archived
Certificate of Testing for Lot # 20147A2
Certificate of Analysis for Lot # 20147A1
Certificate of Analysis for Lot # 20146A1
Certificate of Analysis for Lot # 20144A2
Certificate of Analysis for Lot # 20146A1
Certificate of Analysis for Lot # 20146A2
SDS

201-sdsv1-81-1-pdf

$325.00

#203A (2.5 mg)

LPS from Escherichia coli O55:B5

Info

HIGHLY PURIFIED BACTERIAL LPS PRODUCT BULLETIN
APOPTOSIS PRODUCT BULLETIN
COA

Current
Certificate of Testing for Lot # 20327A4
Certificate of Testing for Lot # 20327A2
Archived
Certificate of Testing for Lot # 20328A1
Certificate of Testing for Lot # 20326A2 v03
Certificate of Testing for Lot # 20326B2 v02
Certificate of Analysis for Lot # 20324A1
Certificate of Analysis for Lot # 20323B1
Certificate of Analysis for Lot # 20323B2
Certificate of Analysis for Lot # 20321A6
SDS

203-sdsv1-82-1-pdf

$360.00

#225 (5 mg)

LPS from Salmonella typhimurium

Info

HIGHLY PURIFIED BACTERIAL LIPOPOLYSACCHARIDES AND RELATED PRODUCTS
APOPTOSIS PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 2258A2
Archived
Certificate of Analysis for Lot # 2258A1
SDS

225-sdsv1-85-1-pdf

$220.00

#301 (5 mg)

LPS from Escherichia coli J5 (Rc)

This product is discontinued.

Info

HIGHLY PURIFIED BACTERIAL LIPOPOLYSACCHARIDES AND RELATED PRODUCTS
APOPTOSIS PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 30131A1
Archived
Certificate of Analysis for Lot # 30130A1
Certificate of Analysis for Lot # 30130A2
SDS

301-sdsv1-86-1-pdf

#302 (5 mg)

LPS from Escherichia coli K12, D31m4 (Re)

Info

HIGHLY PURIFIED BACTERIAL LIPOPOLYSACCHARIDES AND RELATED PRODUCTS
APOPTOSIS PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 3029A1 v03
Archived
Certificate of Analysis for Lot # 3027A1
SDS

302-sdsv1-87-1-pdf

$200.00

#304 (5 mg)

LPS from Salmonella minnesota R595 (Re)

Info

HIGHLY PURIFIED BACTERIAL LIPOPOLYSACCHARIDES AND RELATED PRODUCTS
APOPTOSIS PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 30448A1
Archived
Certificate of Analysis for Lot # 30446A1
SDS

304-sdsv1-88-1-pdf

$220.00

#314 (1 mg)

LPS from Escherichia coli K12 strain LCD25

Info

HIGHLY PURIFIED BACTERIAL LIPOPOLYSACCHARIDES AND RELATED PRODUCTS
COA

Current
Certificate of Analysis for Lot # 3141C1 v02
SDS

314-sdsv1-89-1-pdf

$200.00

#401 (1 mg)

LIPID A monophosphoryl from Salmonella minnesota R595

Info

HIGHLY PURIFIED BACTERIAL LIPOPOLYSACCHARIDES AND RELATED PRODUCTS
COA

Current
Certificate of Analysis for Lot # 40140A1
Archived
Certificate of Analysis for Lot # 40138A
Certificate of Analysis for Lot # 40139A1
SDS

non-hazardous-statement-lps-and-related-91-1-pdf

$240.00

#421 (1 mg)

ULTRA PURE LPS from Escherichia coli O111:B4

This product is discontinued.

Info

HIGHLY PURIFIED BACTERIAL LIPOPOLYSACCHARIDES AND RELATED PRODUCTS
COA

Current
Certificate of Analysis for Lot # 4219A1
Archived
Certificate of Analysis for Lot # 4216A3
Certificate of Analysis for Lot # 4217A1
Certificate of Analysis for Lot # 4218A1
Certificate of Analysis for Lot # 4218A1
SDS

421-sdsv1-92-1-pdf

#423 (1 mg)

ULTRA PURE LPS from Escherichia coli O55:B5

This product is discontinued.

Info

HIGHLY PURIFIED BACTERIAL LIPOPOLYSACCHARIDES AND RELATED PRODUCTS
COA

Current
Certificate of Analysis for Lot # 4231A1
SDS

423-sdsv1-123-1-pdf

#433 (1 mg)

LIST™ HPT™ from Escherichia coli O113

This product is discontinued.

Info

HIGHLY PURIFIED BACTERIAL LIPOPOLYSACCHARIDES AND RELATED PRODUCTS
COA

Current
Certificate of Analysis for Lot # 4331B1 v03
SDS

433-sdsv1-193-1-pdf

#434 (1 mg)

ULTRA PURE LPS from Salmonella minnesota R595 (Re)

Info

APOPTOSIS PRODUCT BULLETIN
HIGHLY PURIFIED BACTERIAL LPS PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 4345A1
Archived
Certificate of Analysis for Lot # 4343A1
Certificate of Analysis for Lot # 4345A1
SDS

434-sdsv1-93-1-pdf

$285.00

#500A (100 ug)

SNAP-25 Recombinant Protein Substrate for C. botulinum Types A and E Neurotoxin

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 5004A1 v02
Archived
Certificate of Analysis for Lot # 5003A1
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-96-1-pdf

$410.00

#520 (200 nmoles)

SNAPtide® Peptide Substrate (o-Abz/Dnp) for C. botulinum Type A Neurotoxin

Info

BOTULINUM NEUROTOXINS PRODUCT BULLETIN
SNAPTIDE, VAMPTIDE, SYNTAXTIDE, AND SNAP ETIDE PRODUCT BULLETIN
COA

Current
Certificate of Testing for Lot 52011A1
Certificate of Testing for Lot 52010A2
Archived
Certificate of Testing for Lot 52010A1
Certificate of Testing for Lot # 5209A5 v01
Certificate of Analysis for Lot # 5209A4 v01
Certificate of Analysis for Lot # 5209A2
Certificate of Analysis for Lot # 5209A1
Certificate of Analysis for Lot # 5209A3
Certificate of Analysis for Lot # 5108A1
Certificate of Analysis for Lot # 5208A3
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-98-1-pdf
Poster

Current
SENSITIVE DETECTION OF BOTULINUM NEUROTOXIN TYPE A USING HIGH AFFINITY POLYCLONAL ANTIBODIES
Comparison of Activity of Botulinum Neurotoxin Type A Holotoxin and Light Chain Using SNAPtide ® FRET Substrates
FRET peptide substrates for the Botulinum toxins type A, B, and E and for anthrax lethal factor
Capture Assay for Botulinum Neurotoxin Type A Utilizing the Neuronal Receptor Protein SV2c
Functional Assay for Botulinum Neurotoxin Type A Utilizing the Neuronal Receptor Protein SV2c
Sensitive, In Vitro, Bifunctional, Potency Assay For Botulinum Neurotoxin Type A
FRET Peptide Substrates for Botulinum Neurotoxins Types A, B, C, and E
EVALUATION OF A SMALL PEPTIDE INHIBITOR AND A CONTROL PEPTIDE FOR BOTULINUM NEUROTOXIN, TYPE A
ULTRA SENSITIVE HPLC DETECTION ASSAY FOR BOTULINUM NEUROTOXIN TYPE A
NEW SV2c CONSTRUCT FOR USE IN BINDING AND DETECTING BOUTULINUM NEUROTOXIN TYPE A
SENSITIVE AND SPECIFIC BIFUNCTIONAL ASSAY FOR BOTULINUM NEUROTOXIN TYPE A

$970.00

#521 (200 nmoles)

SNAPtide® Peptide Substrate (FITC/DABCYL) for C. botulinum Type A Neurotoxin

This product is discontinued.

Info

BOTULINUM NEUROTOXINS PRODUCT BULLETIN
SNAPTIDE, VAMPTIDE, SYNTAXTIDE, AND SNAP ETIDE PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 5214A3 v02
Archived
Certificate of Analysis for Lot # 5213A2
Certificate of Analysis for Lot # 5214A2
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-99-1-pdf
Poster

Current
EVALUATION OF A SMALL PEPTIDE INHIBITOR AND A CONTROL PEPTIDE FOR BOTULINUM NEUROTOXIN, TYPE A
FRET Peptide Substrates for Botulinum Neurotoxins Types A, B, C, and E
Comparison of Activity of Botulinum Neurotoxin Type A Holotoxin and Light Chain Using SNAPtide ® FRET Substrates
NEW FRET SUBSTRATE FOR BOTULINUM NEUROTOXIN TYPE A
FRET peptide substrates for the Botulinum toxins type A, B, and E and for anthrax lethal factor

#523 (200 nmoles)

SNAPtide® Peptide Substrate flP6(DABCYL/5-IAF) for C. botulinum Type A Neurotoxin

Info

BOTULINUM NEUROTOXINS
COA

Current
Certificate of Analysis for Lot # 5232A1 v02
Archived
Certificate of Analysis for Lot # 5231A1
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-183-1
Poster

Current
NEW FRET SUBSTRATE FOR BOTULINUM NEUROTOXIN TYPE A

$600.00

#525 (200 nmoles)

Control Peptide for SNAPtide® 520 Substrate for C. botulinum Type A Neurotoxin

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 5252A1 v02
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-169-1-pdf
Poster

Current
EVALUATION OF A SMALL PEPTIDE INHIBITOR AND A CONTROL PEPTIDE FOR BOTULINUM NEUROTOXIN, TYPE A

$600.00

#526 (200 nmoles)

Control Peptide for SNAPtide® 521 for C. botulinum Type A Neurotoxin

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 5261A1 v02
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-186-1-pdf

$600.00

#528 (50 nmoles)

Unquenched Calibration Peptide for SNAPtide® 521 Substrate for C. botulinum Type A Neurotoxin

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 5281A2
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-100-1-pdf
Poster

Current
NEW FRET SUBSTRATE FOR BOTULINUM NEUROTOXIN TYPE A
Comparison of Activity of Botulinum Neurotoxin Type A Holotoxin and Light Chain Using SNAPtide ® FRET Substrates

#529 (50 nmoles)

Unquenched Calibration Peptide for SNAPtide® 520 Substrate for C. botulinum Type A Neurotoxin

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 5292A2 v02
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-101-1-pdf
Poster

Current
SENSITIVE AND SPECIFIC BIFUNCTIONAL ASSAY FOR BOTULINUM NEUROTOXIN TYPE A
Comparison of Activity of Botulinum Neurotoxin Type A Holotoxin and Light Chain Using SNAPtide ® FRET Substrates

$250.00

#530 (200 nmoles)

MAPKKide® Peptide Substrate (o-Abz/Dnp) for Anthrax Lethal Factor

Product # 530 is MAPKKide® utilizing the o-Abz/Dnp FRET pair. A calibration peptide, Product #539 is available for convenient use with the quenched substrate.

Info

MAPKKIDE PLUS PRODUCT BULLETIN
ANTHRAX TOXIN PRODUCT BULLETIN
MAPKKIDE PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 5303A6
Certificate of Analysis for Lot # 5303A5
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-102-1-pdf
Poster

Current
Internally Quenched Fluorogenic Substrates for Anthrax Lethal Factor
Physical Characteristics of rLF and rPA: Effects on Enzymatic Activity and Binding
FRET Peptide Substrates for the Botulinum Toxins Type A, B, and E and for Anthrax Lethal Factor

$365.00

#531 (200 nmoles)

MAPKKide® Peptide Substrate (DABCYL/FITC) for Anthrax Lethal Factor

This product is discontinued.Product # 531 is MAPKKide® with the FRET pair DABCYL/FITC.

Info

MAPKKIDE PLUS PRODUCT BULLETIN
ANTHRAX TOXIN PRODUCT BULLETIN
MAPKKIDE PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 5313A1
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-103-1-pdf
Poster

Current
FRET peptide substrates for the Botulinum toxins type A, B, and E and for anthrax lethal factor

#532 (100 nmoles)

MAPKKide® Plus (AMC) Specific Substrate for Anthrax Lethal Factor

Product # 532 is MAPKKide® Plus Specific Substrate for Anthrax Lethal Factor. This peptide is remarkable in its resistance to non-specific cleavage by enzymes which may be present in natural samples. MAPKKide® Plus carries the fluorophore 7-amido-4-methylcoumarin (AMC).

Info

MAPKKIDE PRODUCT BULLETIN
MAPKKIDE PLUS PRODUCT BULLETIN
ANTHRAX TOXIN PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 5321A1
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-251-1-pdf
Poster

Current
Sensitive Detection of Anthrax Lethal Factor in Plasma Using a Specific Biotinylated Fluorogenic Substrate
MAPKKide® Plus: A Specific Substrate for Sensitive Detection of Anthrax Lethal Factor in Complex Matrices
Fluorescence Substrate for Specific and Quantitative Detection of Anthrax Lethal Factor in Plasma
Substrate for Specific Lethal Factor
Specific Detection of Anthrax Infection

$305.00

#539 (50 nmoles)

Unquenched Calibration Peptide for MAPKKide® 530 for Anthrax Lethal Factor

This product is discontinued.

Info

MAPKKIDE PLUS PRODUCT BULLETIN
ANTHRAX TOXIN PRODUCT BULLETIN
MAPKKIDE PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 5391A2
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-104-1-pdf
Poster

Current
Physical Characteristics of rLF and rPA: Effects on Enzymatic Activity and Binding

#540 (200 nmoles)

VAMPtide® Peptide Substrate (o-Abz/Dnp) Substrate for C. botulinum Type B Neurotoxin

This product is discontinued.

Info

BOTULINUM NEUROTOXINS PRODUCT BULLETIN
SNAPTIDE, VAMPTIDE, SYNTAXTIDE, AND SNAP ETIDE PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 5404A1
Archived
Certificate of Analysis for Lot # 5403A1
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-105-1-pdf
Poster

Current
EVALUATION OF THREE VAMPTIDE® SUBSTRATES FOR BOTULINUM NEUROTOXIN TYPE B
FRET Peptide Substrates for Botulinum Neurotoxins Types A, B, C, and E
FRET peptide substrates for the Botulinum toxins type A, B, and E and for anthrax lethal factor
Comparison of Activity of Botulinum Neurotoxin Type A Holotoxin and Light Chain Using SNAPtide ® FRET Substrates

#541 (200 nmoles)

VAMPtide® Peptide Substrate (FITC/DABCYL) Substrate for C. botulinum Type B Neurotoxin

Info

BOTULINUM NEUROTOXINS PRODUCT BULLETIN
SNAPTIDE, VAMPTIDE, SYNTAXTIDE, AND SNAP ETIDE PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 5411A1 v02
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-170-1-pdf
Poster

Current
EVALUATION OF THREE VAMPTIDE® SUBSTRATES FOR BOTULINUM NEUROTOXIN TYPE B

$600.00

#542 (200 nmoles)

VAMPtide® (Pya/Nop) Peptide Substrate for Botulinum Neurotoxin Type B

Info

BOTULINUM NEUROTOXINS
FRET Peptides Native Substrates and Receptors
COA

Current
Certificate of Analysis for Lot # 5421A1
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-190-1-pdf
Poster

Current
EVALUATION OF THREE VAMPTIDE® SUBSTRATES FOR BOTULINUM NEUROTOXIN TYPE B

$600.00

#549 (100 nmoles)

Calibration Fluorophore for VAMPtide® 540 Substrate for C. botulinum Type B Neurotoxin

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 5491A1
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-147-1-pdf

$205.00

#550 (100 nmoles)

SNAP Etide® Peptide Substrate (o-Abz/Dnp) for C. botulinum Type E Neurotoxin

This product is discontinued.

Info

BOTULINUM NEUROTOXINS PRODUCT BULLETIN
SNAPTIDE, VAMPTIDE, SYNTAXTIDE, AND SNAP ETIDE PRODUCT BULLETIN
COA

Archived
Certificate of Testing for Lot # 5504A1
Certificate of Analysis for Lot # 5503A1 v02
Certificate of Analysis for Lot # 5502A1
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-106-1-pdf
Poster

Current
FRET Peptide Substrates for Botulinum Neurotoxins Types A, B, C, and E
SNAP EtideTM, a FRET Substrate for BotulinumToxin Type E
FRET peptide substrates for the Botulinum toxins type A, B, and E and for anthrax lethal factor

#559 (50 nmoles)

Unquenched Calibration Peptide for SNAP Etide® Prod #550

COA

Current
Certificate of Analysis for Lot # 5591A1 v02
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-256-1-pdf

$290.00

#560 (200 nmoles)

SYNTAXtide® (o-Abz/Dnp) Peptide Substrate for C. botulinum Type C Neurotoxin

Info

BOTULINUM NEUROTOXINS PRODUCT BULLETIN
SNAPTIDE, VAMPTIDE, SYNTAXTIDE, AND SNAP ETIDE PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 5602A1
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-144-1-pdf
Poster

Current
Ultra Sensitive HPLC Detection Assay for Botulinum Neurotoxin Type A
FRET Peptide Substrates for Botulinum Neurotoxins Types A, B, C, and E

$555.00

#611A (15 ug)

Botulinum Neurotoxin Type A Light Chain, Recombinant, GST Fusion

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 6112A1
Archived
Certificate of Analysis for Lot # 6111A1
N-HAZ

non-hazardous-statement-recombinant-chains-23-1-pdf

$310.00

#612A (50 ug)

Botulinum Neurotoxin Type A Heavy Chain, Recombinant, Binding Domain

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 6123A1
Archived
Certificate of Analysis for Lot # 6121A1
Certificate of Analysis for Lot # 6122A1
N-HAZ

non-hazardous-statement-recombinant-chains-153-1-pdf
Poster

Current
New High Affinity Antibodies Against Botulinum Neurotoxin Type A

#613A (50 ug)

Botulinum Neurotoxin Type A Heavy Chain, Recombinant, Binding Domain, GST Fusion

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 6131B1
N-HAZ

non-hazardous-statement-recombinant-chains-149-1-pdf

#620A (10 ug)

Botulinum Neurotoxin Type B Light Chain, Recombinant

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 62015A1
Archived
Certificate of Analysis for Lot # 6206A1
N-HAZ

non-hazardous-statement-recombinant-chains-24-1-pdf
Poster

Current
EVALUATION OF THREE VAMPTIDE® SUBSTRATES FOR BOTULINUM NEUROTOXIN TYPE B
FRET Peptide Substrates for Botulinum Neurotoxins Types A, B, C, and E
Comparison of Activity of Botulinum Neurotoxin Type A Holotoxin and Light Chain Using SNAPtide ® FRET Substrates

$555.00

#622A (50 ug)

Botulinum Neurotoxin Type B Heavy Chain, Recombinant, Binding Domain

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 6222A1
Archived
Certificate of Analysis for Lot # 6221A1
N-HAZ

non-hazardous-statement-recombinant-chains-152-1-pdf

#623A (50 ug)

Botulinum Neurotoxin Type B Heavy Chain, Recombinant, Binding Domain, GST Fusion

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 6231A1
N-HAZ

non-hazardous-statement-recombinant-chains-150-1-pdf

#625A (10 ug)

Botulinum Neurotoxin Type C Light Chain, Recombinant

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 6256A1
Archived
Certificate of Analysis for Lot # 6253A1
N-HAZ

non-hazardous-statement-recombinant-chains-25-1-pdf
Poster

Current
FRET Peptide Substrates for Botulinum Neurotoxins Types A, B, C, and E
Ultra Sensitive HPLC Detection Assay for Botulinum Neurotoxin Type A

$555.00

#630A (10 ug)

Botulinum Neurotoxin Type D Light Chain, Recombinant

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 6301A1 v02
N-HAZ

non-hazardous-statement-recombinant-chains-26-1-pdf

#690B (100 ug)

Receptor for Clostridium botulinum Type A Neurotoxin, GST-SV2c luminal domain

This product is discontinued.

Info

Technical Info
COA

Archived
Certificate of Testing for Lot # 6906A1
Certificate of Analysis for Lot # 6905A1
Certificate of Analysis for Lot # 6904A1
Certificate of Analysis for Lot # 6902A1
N-HAZ

non-hazardous-statement-recombinant-chains-194-1-pdf
Poster

Current
SENSITIVE AND SPECIFIC BIFUNCTIONAL ASSAY FOR BOTULINUM NEUROTOXIN TYPE A
Ultra Sensitive HPLC Detection Assay for Botulinum Neurotoxin Type A
Functional Assay for Botulinum Neurotoxin Type A Utilizing the Neuronal Receptor Protein SV2c
Capture Assay for Botulinum Neurotoxin Type A Utilizing the Neuronal Receptor Protein SV2c
Sensitive, In Vitro, Bifunctional, Potency Assay For Botulinum Neurotoxin Type A

#703 (0.1 ml)

Anti-Cholera Toxin B Subunit (Goat)

Info

FITC AND BIOTIN CONJUGATES OF CHOLERA TOXIN B SUBUNIT
CHOLERA TOXIN PRODUCT BULLETIN
COA

Current
Certificate of Testing for Lot # 7032A12
Certificate of Testing for Lot # 7032A11
Archived
Certificate of Analysis for Lot # 7032A10
Certificate of Analysis for Lot # 7032A9
Certificate of Analysis for Lot # 7032A6
Certificate of Analysis for Lot # 7032A7
Certificate of Analysis for Lot # 7032A8
N-HAZ

non-hazardous-statement-antisera-and-antibodies-110-1-pdf

$320.00

#730A (0.1 mg)

Anti-Botulinum Neurotoxin, Type A (Chicken lgY)

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Testing for Lot # 7304A1
Archived
Certificate of Analysis for Lot # 7303A1
Certificate of Analysis for Lot # 7302A1
Certificate of Analysis for Lot # 7302B2
Certificate of Analysis for Lot # 7302A1
N-HAZ

non-hazardous-statement-antisera-and-antibodies-140-1-pdf
Poster

Current
New High Affinity Antibodies Against Botulinum Neurotoxin Type A
SENSITIVE DETECTION OF BOTULINUM NEUROTOXIN TYPE A USING HIGH AFFINITY POLYCLONAL ANTIBODIES

#731L (0.1 mg)

Anti-Botulinum Neurotoxin, Type A (Mouse lgG monoclonal F1-40), Frozen Liquid

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 7311A2 v02
N-HAZ

non-hazardous-statement-antisera-and-antibodies-197-1-pdf
Poster

Current
New High Affinity Antibodies Against Botulinum Neurotoxin Type A
ULTRA SENSITIVE HPLC DETECTION ASSAY FOR BOTULINUM NEUROTOXIN TYPE A

$435.00

#752 (0.5 ml)

Anti-Toxin A from Clostridium difficile (Goat)

This product is discontinued.

Info

C. DIFFICILE TOXINS PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Analysis for Lot # 7521A2 v02
Archived
Certificate of Analysis for Lot # 7521A
N-HAZ

non-hazardous-statement-antisera-and-antibodies-111-1-pdf

#753A (0.1 mg)

Anti-Clostridium difficile Toxin A (Chicken lgY)

This product is discontinued.

Info

C. DIFFICILE TOXINS PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Analysis for Lot # 7531A2
Archived
Certificate of Analysis for Lot # 7531A1
N-HAZ

non-hazardous-statement-antisera-and-antibodies-160-1-pdf

#754A (0.1 mg)

Anti-Clostridium difficile Toxin B (Chicken lgY)

This product is discontinued.

Info

C. DIFFICILE TOXINS PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Analysis for Lot # 7542A1
N-HAZ

non-hazardous-statement-antisera-and-antibodies-196-1-pdf

#756A (0.1 mg)

Anti-Glutamate Dehydrogenase from Clostridium difficile lgY

This product is discontinued.

Info

C. DIFFICILE TOXINS PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Analysis for Lot # 7561A2
N-HAZ

non-hazardous-statement-antisera-and-antibodies-223-1-pdf

#757A (0.1 mg)

Anti-Clostridium difficile Binary Toxin A subunit (Chicken lgY)

This product is discontinued.

Info

C. DIFFICILE TOXINS PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Analysis for Lot # 7572A1
Archived
Certificate of Analysis for Lot # 7571A1
N-HAZ

non-hazardous-statement-antisera-and-antibodies-221-1-pdf

#758A (0.1 mg)

Anti-Clostridium difficile Binary Toxin B Subunit (Chicken lgY)

This product is discontinued.

Info

C. DIFFICILE TOXINS PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Analysis for Lot # 7582A1
Archived
Certificate of Analysis for Lot # 7581A1
N-HAZ

non-hazardous-statement-antisera-and-antibodies-212-1-pdf

#759A (0.1 mg)

Biotinylated Anti-Clostridium difficile Binary Toxin B Subunit (Chicken lgY)

This product is discontinued.

Info

C. DIFFICILE TOXINS PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Analysis for Lot # 7591A1
N-HAZ

non-hazardous-statement-antisera-and-antibodies-213-1-pdf

#761L (Liquid)

Anti-Shiga Toxin 1, Rabbit lgG

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 7611A1
N-HAZ

non-hazardous-statement-antisera-and-antibodies-248-1-pdf

#766L (Liquid)

Anti-Shiga Toxin, Camelid Antibody, VHH

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 7661A1
N-HAZ

non-hazardous-statement-antisera-and-antibodies-246-1-pdf

#768L (Liquid)

Anti-B. anthracis Lethal Factor (LF-A), lgY Antibody, Biotinylated

Product # 768L affinity purified and biotinylated Anti-Lethal Factor from B. anthracis (chicken lgY) works to detect the LF as described in the C of A.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 7681A1
N-HAZ

non-hazardous-statement-antisera-and-antibodies-245-1-pdf

$415.00

#771B (1 mg)

Anti-Protective Antigen from B. anthracis (Goat)

This product is discontinued.Products # 771, purified IgG from goat, is directed to PA.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 7712A3
Certificate of Analysis for Lot # 7712A2
Archived
Certificate of Analysis for Lot # 7711A6
Certificate of Analysis for Lot # 7712A1
N-HAZ

non-hazardous-statement-antisera-and-antibodies-115-1-pdf

#773L (Liquid)

Anti-Edema Factor from B. anthracis (Goat)

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 7732A3
N-HAZ

non-hazardous-statement-antisera-and-antibodies-117-1-pdf

T cell-independent modulation of experimental autoimmune encephalomyelitis in ADAP-deficient mice.

The Journal of Immunology

Engelmann, S;Togni, M;Thielitz, A;Reichardt, P;Kliche, S;Reinhold, D;Schraven, B;Reinhold, A;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

The adhesion- and degranulation-promoting adaptor protein (ADAP), expressed in T cells, myeloid cell....

An electrophysiologic approach to quantify impaired synaptic transmission and plasticity in experimental autoimmune encephalomyelitis

Journal Of Neuroimmunology

Prochnow, N;Gold, R;Haghikia, A;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Despite its various limitations, for many decades the experimental autoimmune encephalomyelitis (EAE....

Lipopolysaccharide stimulates platelets through an IL-1 autocrine loop

The Journal of Immunology

Brown, GT;Narayanan, P;Li, W;Silverstein, RL;McIntyre, TM;

Product: ULTRA PURE LPS from Escherichia coli O111:B4

LPS activates platelets through TLR4, aiding productive sepsis, with stimulated splicing and transla....

Orexin neurons are indispensable for prostaglandin E2-induced fever and defence against environmental cooling in mice

The Journal of Physiology

Takahashi, Y;Zhang, W;Sameshima, K;Kuroki, C;Matsumoto, A;Sunanaga, J;Kono, Y;Sakurai, T;Kanmura, Y;Kuwaki, T;

Product: Anti-Cholera Toxin B Subunit (Goat)

We recently showed using prepro-orexin knockout (ORX-KO) mice and orexin neuron-ablated (ORX-AB) mic....

Medial habenula output circuit mediated by 5 nicotinic receptor-expressing GABAergic neurons in the interpeduncular nucleus.

The Journal of Neuroscience

Hsu, YW;Tempest, L;Quina, LA;Wei, AD;Zeng, H;Turner, EE;

Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

The Chrna5 gene encodes the 5 nicotinic acetylcholine receptor subunit, an accessory subunit of pent....

Role of sphingosine 1-phosphate (S1P) receptor 1 in experimental autoimmune encephalomyelitisI

Pharmacology & Pharmacy , 2013, 4, 628-637

Seki, N;Maeda, Y;Kataoka, H;Sugahara, K;Chi, K;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Infiltration of myelin-specific helper T (Th) cells into the central nervous system (CNS) plays a ke....

The chemokine receptor CCR1 is constitutively active, which leads to G protein-independent, -arrestin-mediated internalization.

The Journal Of Biological Chemistry

Gilliland, CT;Salanga, CL;Kawamura, T;Trejo, J;Handel, TM;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Activation of G protein-coupled receptors by their associated ligands has been extensively studied, ....

Genetic identification of a neural circuit that suppresses appetite

Nature

Carter, ME;Soden, ME;Zweifel, LS;Palmiter, RD;

Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae

Appetite suppression occurs after a meal and in conditions when it is unfavourable to eat, such as d....

Immunity against a Chlamydia infection and disease may be determined by a balance of IL-17 signaling.

Immunololgy And Cell Biology

O'Meara, CP;Armitage, CW;Harvie, MC;Andrew, DW;Timms, P;Lycke, NY;Beagley, KW;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

Most vaccines developed against Chlamydia using animal models provide partial protection against a g....

Cholera toxin enhances vaccine-induced protection against Mycobacterium tuberculosis challenge in mice

PLoS ONE

Griffiths, KL;Stylianou, E;Poyntz, HC;Betts, GJ;Fletcher, HA;McShane, H;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

Interleukin (IL)-17 is emerging as an important cytokine in vaccine-induced protection against tuber....

Decreased signal transducers and activators of transcription (STAT) protein expression in lymphatic organs during EAE development in mice

Immunology Innovation

Wu, WX;Zuo, L;Dine, KE;Shindler, KS;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Experimental autoimmune encephalomyelitis (EAE) is mediated by myelin-specific CD4+ T cells secretin....

Dorsal column sensory axons degenerate due to impaired microvascular perfusion after spinal cord injury in rats

Experimental Neurology

Muradov, JM;Ewan, EE;Hagg, T;

Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

The mechanisms contributing to axon loss after spinal cord injury (SCI) are largely unknown but may ....

Defective sphingosine 1-phosphate receptor 1 (S1P1) phosphorylation exacerbates TH17-mediated autoimmune neuroinflammation

Nature Immunology

Garris, CS;Wu, L;Acharya, S;Arac, A;Blaho, VA;Huang, Y;Moon, BS;Axtell, RC;Ho, PP;Steinberg, GK;Lewis, DB;Sobel, RA;Han, DK;Steinman, L;Snyder, MP;Hla, T;Han, MH;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Sphingosine 1-phosphate (S1P) signaling regulates lymphocyte egress from lymphoid organs into system....

Itch expression by Treg cells controls Th2 inflammatory responses

The Journal of Clinical Investigation

Jin, HS;Park, Y;Elly, C;Liu, YC;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Regulatory T (Treg) cells maintain immune homeostasis by limiting autoimmune and inflammatory respon....

Th1-mediated experimental autoimmune encephalomyelitis is CXCR3 independent

European Journal Of Immunology

Lalor, SJ;Segal, BM;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Drugs that block leukocyte trafficking ameliorate multiple sclerosis (MS). Occurrences of opportunis....

Serum exosomes in pregnancy-associated immune modulation and neuroprotection during CNS autoimmunity

Clinical Immunology

Williams, JL;Gatson, NN;Smith, KM;Almad, A;McTigue, DM;Whitacre, CC;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

In multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE), relapses are markedl....

ITE, a novel endogenous nontoxic aryl hydrocarbon receptor ligand, efficiently suppresses EAU and T-cell-mediated immunity

Investigative Ophthalmology And Visual Science

Nugent, LF;Shi, G;Vistica, BP;Ogbeifun, O;Hinshaw, SJ;Gery, I;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Ligands for aryl hydrocarbon receptor (AHR), such as dioxins, are highly toxic. One such ligand, TCD....

Responses of different geographic populations of two potato tuber moth species to genetic variants of Phthorimaea operculella granulovirus

Entomologia Experimentalis et Applicata

Zeddam, J;Lery, X;YanneryG-omez-Bonilla, ;Espinel-Correal, C;Paez, D;Rebaudo, F;L-opez-Ferber, M;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Phthorimaea operculella granulovirus (PhopGV) belongs to the genus Betabaculovirus of the arthropod-....

Proapoptotic chemotherapeutic drugs induce noncanonical processing and release of IL-1 via caspase-8 in dendritic cells

The Journal of Immunology

Antonopoulos, C;El Sanadi, C;Kaiser, WJ;Mocarski, ES;Dubyak, GR;

Product: LPS from Escherichia coli O111:B4

The identification of noncanonical (caspase-1-independent) pathways for IL-1 production has unveiled....

Persistence of LPS-induced lung inflammation in surfactant protein-C-deficient mice

American Journal Of Respiratory Cell And Molecular Biology

Glasser, SW;Maxfield, MD;Ruetschilling, TL;Akinbi, HT;Baatz, JE;Kitzmiller, JA;Page, K;Xu, Y;Bao, EL;Korfhagen, TR;

Product: LPS from Escherichia coli O111:B4

Pulmonary surfactant protein-C (SP-C) gene-targeted mice (Sftpc(-/-)) develop progressive lung infla....

The Generation of Synthetic Antibody Reagents for Clostridium difficile Toxins

Thesis

Wong, SCM;

Product: Toxin A from Clostridium difficile

Biophysical characterization and immunization studies of dominant negative inhibitor (DNI), a candidate anthrax toxin subunit vaccine

Human Vaccines And Immunotherapeutics

Iyer, V;Hu, L;Schant, CE;Vance, D;Chadwick, C;Jain, NK;Brey, RN;Joshi, SB;Volkin, DB;Andra, KK;Bann, JG;Mantis, NJ;Middaugh, CR;

Product: Anthrax Protective Antigen (PA), Recombinant from B. anthracis

Dominant Negative Inhibitor (DNI) is a translocation-deficient homolog of recombinant protective ant....

Mouse in vivo neutralization of Escherichia coli Shiga toxin 2 with monoclonal antibodies.

Toxins

Cheng, LW;Henderson, TD;Patfield, S;Stanker, LH;He, X;

Product: Shiga Toxin 2 from Escherichia coli

Shiga toxin-producing Escherichia coli (STEC) food contaminations pose serious health concerns, and ....

A polyclonal antibody based immunoassay detects seven subtypes of Shiga toxin 2 produced by Escherichia coli in human and environmental samples

PLoS ONE

He, X;Patfield, S;Hnasko, R;Rasooly, R;Mandrell, RE;

Product: Shiga Toxin 1 from Escherichia coli

Shiga toxin-producing Escherichia coli (STEC) are frequent causes of severe human diseases ranging f....

Ischemia-reperfusion lung injury is attenuated in MyD88-deficient mice

PLoS ONE

Altemeier, WA;Liles, WC;Villagra-Garcia, A;Matute-Bello, G;Glenny, RW;

Product: LPS from Escherichia coli O111:B4

Ischemia-reperfusion lung injury is a common cause of acute morbidity and mortality in lung transpla....

Bioluminescence assay for the highly sensitive detection of botulinum neurotoxin A activity

Analyst

Stevens, GB;Silver, DA;Zgaga-Griesz, A;Bessler, WG;Vashist, SK;Patel, P;Achazi, K;Strotmeier, J;Worbs, S;Dorner, MB;Dorner, BG;Pauly, D;Rummel, A;Urban, GA;Krueger, M;

Product: SNAPtide® Peptide Substrate (FITC/DABCYL) for C. botulinum Type A Neurotoxin

This article describes a novel bioluminescence assay for detecting the proteolytic activity of Botul....

Substrate Cleavage Profiling Suggests a Distinct Function of Bacteroides fragilis Metalloproteinases (Fragilysin and Metalloproteinase II) at the Microbiome-Inflammation-Cancer Interface

Journal Of Biological Chemistry

Shiryaev, SA;Remacle, AG;Chernov, AV;Golubkov, VS;Motamedchaboki, K;Muranaka, N;Dambacher, CM;Capek, P;Kukreja, M;Kozlov, IA;Perucho, M;Cieplak, P;Strongin, AY;

Product: Anthrax Protective Antigen (PA), Recombinant from B. anthracis

Enterotoxigenic anaerobic Bacteroides fragilis is a significant source of inflammatory diarrheal dis....

TNF-dependent development of lymphoid tissue in the absence of RORt lymphoid tissue inducer cells.

Mucosal Immunology

Furtado, GC;Pacer, ME;Bongers, G;Bnzech, C;He, Z;Chen, L;Berin, MC;Kollias, G;Caamao, JH;Lira, SA;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

Lymphoid tissue often forms within sites of chronic inflammation. Here we report that expression of ....

Organization of multisynaptic circuits within and between the medial and the central extended amygdala

The Journal of Comparative Neurology

Bienkowski, MS;Wendel, ES;Rinaman, L;

Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

The central and medial extended amygdala comprises the central (CEA) and medial nuclei of the amygda....

Regulation of the development of the hepatic B cell compartment during Schistosoma mansoni infection

The Journal of Immunology

Fairfax, KC;Everts, B;Smith, AM;Pearce, EJ;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

During infection with the helminth parasite Schistosoma mansoni, Ab regulates hepatic inflammation, ....

Mimicry epitope from Ehrlichia canis for interphotoreceptor retinoid-binding protein 201-216 prevents autoimmune uveoretinitis by acting as altered peptide ligand

Journal Of Neuroimmunology

Gangaplara, A;Massilamany, C;Steffen, D;Reddy, J;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

We report here identification of novel mimicry epitopes for interphotoreceptor retinoid-binding prot....

Suppression of MOG- and PLP-induced experimental autoimmune encephalomyelitis using a novel multivalent bifunctional peptide inhibitor

Journal Of Neuroimmunology

Badawi, AH;Siahaan, TJ;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Previously, bifunctional peptide inhibitors (BPI) with a single antigenic peptide have been shown to....

One calcitriol dose transiently increases Helios+ FoxP3+ T cells and ameliorates autoimmune demyelinating disease

Journal Of Neuroimmunology

Nashold, FE;Nelson, CD;Brown, LM;Hayes, CE;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Multiple sclerosis (MS) is an incurable inflammatory demyelinating disease. We investigated one calc....

Induction of cyclooxygenase-2 expression by prostaglandin E2 stimulation of the prostanoid EP4 receptor via coupling to Gi and transactivation of the epidermal growth factor receptor in HCA-7 human colon cancer cells.

European Journal Of Pharmacology

Yoshida, K;Fujino, H;Otake, S;Seira, N;Regan, JW;Murayama, T;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Increased expressions of cyclooxygenase-2 (COX-2) and its downstream metabolite, prostaglandin E2 (P....

Inflammasome-mediated secretion of IL-1 in human monocytes through TLR2 activation; modulation by dietary fatty acids

The Journal of Immunology

Snodgrass, RG;Huang, S;Choi, IW;Rutledge, JC;Hwang, DH;

Product: ULTRA PURE LPS from Escherichia coli O111:B4

Many studies have shown that TLR4- and TLR2-deficient mice are protected from high-fat diet-induced ....

Patterns of cortical reorganization in the adult marmoset after a cervical spinal cord injury

The Journal of Comparative Neurology

Bowes, C;Burish, M;Cerkevich, C;Kaas, J;

Product: Anti-Cholera Toxin B Subunit (Goat)

In the present study, we used microelectrode recordings of multiunit responses to evaluate patterns ....

Cholera toxin directly enhances IL-17A production from human CD4+ T cells

The Journal of Immunology

Tsai, HC;Wu, R;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

The significance of Th17 cells and IL-17A signaling in host defense and disease development has been....

Calpain-dependent cytoskeletal rearrangement exploited for anthrax toxin endocytosis

PNAS

Jeong, SY;Martchenko, M;Cohen, SN;

Product: Anthrax Protective Antigen (PA), Recombinant from B. anthracis

The protective antigen component of Bacillus anthracis toxins can interact with at least three disti....

Day-night differences in neural activation in histaminergic and serotonergic areas with putative projections to the cerebrospinal fluid in a diurnal brain

Neuroscience

Castillo-Ruiz, A;Gall, AJ;Smale, L;Nunez, AA;

Product: Anti-Cholera Toxin B Subunit (Goat)

In nocturnal rodents, brain areas that promote wakefulness have a circadian pattern of neural activa....

Anthrax lethal toxin induces acute diastolic dysfunction in rats through disruption of the phospholamban signaling network

International Journal of Cardiology

Golden, HB;Watson, LE;Nizamutdinov, D;Feng, H;Gerilechaogetu, F;Lal, H;Verma, SK;Mukhopadhyay, S;Foster, DM;Dillmann, WH;Dostal, DE;

Product: Anthrax Protective Antigen (PA), Recombinant from B. anthracis

Anthrax lethal toxin (LT), secreted by Bacillus anthracis, causes severe cardiac dysfunction by unkn....

Comprehensive metabolomic analysis of peanut-induced anaphylaxis in a murine model

Metabolomics

Chalcraft, KR;Kong, J;Waserman, S;Jordana, M;McCarry, BE;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

Acute anaphylaxis caused by food allergy is a potentially life-threatening allergic reaction that re....

Increased expression of complement regulators CD55 and CD59 on peripheral blood cells in patients with EAHEC O104:H4 infection

PLoS ONE

Dammermann, W;Schipper, P;Ullrich, S;Fraedrich, K;Schulze Zur Wiesch, J;Frndt, T;Tiegs, G;Lohse, A;Lth, S;

Product: Shiga Toxin 2 from Escherichia coli

An outbreak of Shiga Toxin 2 (Stx-2) producing enterohemorrhagic and enteroaggregative E.coli (EAHEC....

Lentiviral mediated expression of a NGF-soluble Nogo receptor 1 fusion protein promotes axonal regeneration

Neurobiology of Disease

Zhang, Y;Gao, F;Wu, D;Moshayedi, P;Zhang, X;Ellamushi, H;Yeh, J;Priestley, JV;Bo, X;

Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

Nogo receptor 1 (NgR1) mediates the inhibitory effects of several myelin-associated inhibitors (MAIs....

Immunoreactivity for the NMDA NR1 subunit in bulbospinal catecholamine and serotonin neurons of rat ventral medulla

Autonomic Neuroscience

Llewellyn-Smith, IJ;Mueller, PJ;

Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

Bulbospinal neurons in the ventral medulla play important roles in the regulation of sympathetic out....

Altered cognitive-emotional behavior in early experimental autoimmune encephalitis–cytokine and hormonal correlates

Brain, Behavior and Immunity

Acharjee, S;Nayani, N;Tsutsui, M;Hill, MN;Ousman, SS;Pittman, QJ;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Multiple sclerosis (MS) is often associated with co-morbid behavioural and cognitive impairments; ho....

α-Lipoic acid enhances endogenous peroxisome-proliferator-activated receptor-γ to ameliorate experimental autoimmune encephalomyelitis in mice

Clinical Science

Wang, KC;Tsai, CP;Lee, CL;Chen, SY;Lin, GJ;Yen, MH;Sytwu, HK;Chen, SJ;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

ALA (-lipoic acid) is a natural, endogenous antioxidant that acts as a PPAR- (peroxisome-proliferato....

Integrin- FG-GAP repeat-containing protein 2 is critical for normal B cell differentiation and controls disease development in a lupus model

The Journal of Immunology

Al-Shami, A;Crisostomo, J;Wilkins, C;Xu, N;Humphries, J;Chang, WC;Anderson, SJ;Oravecz, T;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

The phenylalanyl-glycyl-glycyl-alanyl-prolyl (FG-GAP) domain plays an important role in protein-prot....

Inhibition of endogenous activated protein C attenuates experimental autoimmune encephalomyelitis by inducing myeloid-derived suppressor cells

The Journal of Immunology

Alabanza, LM;Esmon, NL;Esmon, CT;Bynoe, MS;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Activated protein C (PC) is an anticoagulant involved in the interactions between the coagulation an....

Early axonal damage and progressive myelin pathology define the kinetics of CNS histopathology in a mouse model of multiple sclerosis

Clinical Immunology

Recks, MS;Stormanns, ER;Bader, J;Arnhold, S;Addicks, K;Kuerten, S;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Studies of MS histopathology are largely dependent on suitable animal models. While light microscopi....

Age of the donor reduces the ability of human adipose-derived stem cells to alleviate symptoms in the experimental autoimmune encephalomyelitis mouse model

Stem Cells Translational Medicine

Scruggs, BA;Semon, JA;Zhang, X;Zhang, S;Bowles, AC;Pandey, AC;Imhof, KM;Kalueff, AV;Gimble, JM;Bunnell, BA;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

There is a significant clinical need for effective therapies for primary progressive multiple sclero....

Saturable leptin transport across the BBB persists in EAE mice

Journal Of Molecular Neuroscience

Hsuchou, H;Mishra, PK;Kastin, AJ;Wu, X;Wang, Y;Ouyang, S;Pan, W;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

We have shown that mice with experimental autoimmune encephalomyelitis (EAE), a model of multiple sc....

Contribution of membrane progesterone receptor to the induction of progesterone-mediated apoptosis associated with mitochondrial membrane disruption and caspase cascade activation in Jurkat cell lines

Oncology Reports

Kon, A;Yuan, B;Hanazawa, T;Kikuchi, H;Sato, M;Furutani, R;Takagi, N;Toyoda, H;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

In the present study, we investigated the effects of progesterone (Pg) on the growth of A3 and its c....

Predictability of peripheral lymphocyte reduction of novel S1P1 agonists by in vitro GPCR signaling profile

Journal Of Biomolecular Screening

Xu, H;McElvain, M;Fiorino, M;Henkle, B;Sherman, L;Xu, Y;Tominey, E;Kelley, K;Adlam, M;Brli, R;Siu, J;Wong, M;Cee, VJ;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Surrogate readouts of G-protein-coupled receptor signaling pathways using highly engineered systems ....

Y-39983, a selective Rho-kinase inhibitor, attenuates experimental autoimmune encephalomyelitis via inhibition of demyelination

Neuroimmunomodulation

Gao, C;Huang, L;Long, Y;Zheng, J;Yang, J;Pu, S;Xie, L;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Rho-associated kinase (ROCK) is a serine/threonine kinase and a major downstream effector of the sma....

Characterizing the immunomodulatory effects of the antioxidant TEMPOL in a model of multiple sclerosis

Thesis

Neil, SE;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Maternal immune stimulation during pregnancy shapes the immunological phenotype of offspring

Brain, Behavior and Immunity

Mandal, M;Donnelly, R;Elkabes, S;Zhang, P;Davini, D;David, BT;Ponzio, NM;

Product: Pertussis Toxin from B. pertussis, Lyophilized (Salt-Free)

Epidemiological studies have associated infection during pregnancy with increased risk of neurodevel....

The TNF family member 4-1BBL sustains inflammation by interacting with TLR signaling components during late-phase activation.

Sci Signal

Ma, J;Bang, BR;Lu, J;Eun, SY;Otsuka, M;Croft, M;Tobias, P;Han, J;Takeuchi, O;Akira, S;Karin, M;Yagita, H;Kang, YJ;

Product: LPS from Escherichia coli O111:B4

Activation of Toll-like receptor (TLR)-dependent signaling leads to the expression of genes encoding....

Limiting of the innate immune response by SF3A-dependent control of MyD88 alternative mRNA splicing

PLoS Genetics

De Arras, L;Alper, S;

Product: LPS from Escherichia coli O111:B4

Controlling infectious disease without inducing unwanted inflammatory disease requires proper regula....

Role of antilipopolysaccharide antibodies in serum bactericidal activity against Salmonella enterica serovar Typhimurium in healthy adults and children in the United States

Clinical And Vaccine Immunology

Trebicka, E;Jacob, S;Pirzai, W;Hurley, BP;Cherayil, BJ;

Product: LPS from Salmonella typhimurium

Recent observations from Africa have rekindled interest in the role of serum bactericidal antibodies....

Calpastatin is upregulated in non-immune neuronal cells via toll-like receptor 2 (TLR2) pathways by lipid-containing agonists

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Vaisid, T;Kosower, NS;

Product: LPS from Escherichia coli K12, D31m4 (Re)

Calpain (intracellular Ca(2+)-dependent protease) and calpastatin (calpain specific endogenous inhib....

An interplay between scavenger receptor A and CD14 during activation of J774 cells by high concentrations of LPS

Immunobiology

Czerkies, M;Borzcka, K;Zdioruk, MI;Pciennikowska, A;Sobota, A;Kwiatkowska, K;

Product: ULTRA PURE LPS from Escherichia coli O111:B4

Lipopolysaccharide (LPS) activates macrophages by binding to the TLR4/MD-2 complex and triggers two ....

Oral administration of chitin and chitosan prevents peanut-induced anaphylaxis in a murine food allergy model

International Journal of Biological Macromolecules

Bae, MJ;Shin, HS;Kim, EK;Kim, J;Shon, DH;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

Peanut allergy is IgE-mediated type-I hypersensitivity, and T helper 2 cytokines are central to thos....

The Role of Dendritic Cell Subsets in Cross-presentation and Stimulation of Homing Marker Expression

Thesis

Nizza, SJT;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

Topical antigen (Ag) application mimics natural Ag exposure across the skin. Soluble Ag introduced t....

Comprehensive Metabolomic Analysis in Peanut Sensitization and Peanut-Induced Anaphylaxis: Discovery of Biomarkers and Mediators

Thesis

Kong, J;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

BACKGROUND: The ontogeny of peanut allergy (PA) is poorly understood, and the treatment of its most ....

Potent monoclonal antibodies against Clostridium difficile toxin A elicited by DNA immunization

Human Vaccines And Immunotherapeutics

Zhang, C;Jin, K;Xiao, Y;Cheng, Y;Huang, Z;Wang, S;Lu, S;

Product: Toxin A from Clostridium difficile

Recent studies have demonstrated that DNA immunization is effective in eliciting antigen-specific an....

Transfection in the third dimension

Integrative Biology

Dhaliwal, A;Oshita, V;Segura, T;

Product: Toxin B from Clostridium difficile

An understanding of parameters that modulate gene transfer in 3-D will assist in the formation of ge....

Toxin inhibition of antimicrobial factors induced by Bacillus anthracis peptidoglycan in human blood

Infection And Immunity

Barua, S;Iyer, JK;Larabee, JL;Raisley, B;Hughes, MA;Coggeshall, KM;Ballard, JD;

Product: Anthrax Edema Factor (EF), Recombinant from B. anthracis

Here, we describe the capacity of Bacillus anthracis peptidoglycan (BaPGN) to trigger an antimicrobi....

CD301b+ dermal dendritic cells drive T helper 2 cell-mediated immunity

Immunity

Kumamoto, Y;Linehan, M;Weinstein, JS;Laidlaw, BJ;

Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae

Unlike other types of T helper (Th) responses, whether the development of Th2 cells requires instruc....

The T antigen locus of Merkel cell polyomavirus downregulates human Toll-like receptor 9 expression.

Journal of Virology

Shahzad, N;Shuda, M;Gheit, T;Kwun, HJ;Cornet, I;Saidj, D;Zannetti, C;Hasan, U;Chang, Y;Moore, PS;Accardi, R;Tommasino, M;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

Establishment of a chronic infection is a key event in virus-mediated carcinogenesis. Several cancer....

Proteomic Analysis and Label-Free Quantification of the Large Clostridium difficile Toxins

International Journal Of Proteomics

Moura, H;Terilli, RR;Woolfitt, AR;Williamson, YM;Wagner, G;Blake, TA;Solano, MI;Barr, JR;

Product: Toxin B from Clostridium difficile

Clostridium difficile is the leading cause of antibiotic-associated diarrhea in hospitals worldwide,....

Differential joint-specific corticospinal tract projections within the cervical enlargement

PLoS ONE

Asante, CO;Martin, JH;

Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

The motor cortex represents muscle and joint control and projects to spinal cord interneurons and-in....

Hypoxia-inducible C-to-U coding RNA editing downregulates SDHB in monocytes

PeerJ

Baysal, BE;De Jong, K;Liu, B;Wang, J;Patnaik, SK;Wallace, PK;Taggart, RT;

Product: LPS from Escherichia coli O111:B4

Background. RNA editing is a post-transcriptional regulatory mechanism that can alter the coding seq....

A TREM-1 Polymorphism A/T within the Exon 2 Is Associated with Pneumonia in Burn-Injured Patients

ISRN Inflammation

Rivera-Chvez, FA;Huebinger, RM;Burris, A;Liu, MM;Minei, JP;Hunt, JL;Arnoldo, BD;Barber, RC;

Product: LPS from Escherichia coli K12 strain LCD25

Background. The triggering receptor expressed in myeloid cells (TREM-1) is a key mediator in the act....

Identification of potential cytokine pathways for therapeutic intervention in murine primary biliary cirrhosis

PLoS ONE

Kawata, K;Tsuda, M;Yang, GX;Zhang, W;Tanaka, H;Tsuneyama, K;Leung, P;He, XS;Knechtle, S;Ansari, AA;Coppel, RL;Gershwin, ME;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Primary biliary cirrhosis (PBC) is considered a model autoimmune disease, with the most highly direc....

BAD dephosphorylation and decreased expression of MCL-1 induce rapid apoptosis in prostate cancer cells

PLoS ONE

Yancey, D;Nelson, KC;Baiz, D;Hassan, S;Flores, A;Pullikuth, A;Karpova, Y;Axanova, L;Moore, V;Sui, G;Kulik, G;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

PTEN loss and constitutive activation of the PI3K signaling pathway have been associated with advanc....

Grape extracts inhibit multiple events in the cell biology of cholera intoxication

PLoS ONE

Reddy, S;Taylor, M;Zhao, M;Cherubin, P;Geden, S;Ray, S;Francis, D;Teter, K;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

Vibrio cholerae produces cholera toxin (CT), an AB5 protein toxin that is primarily responsible for ....

Dermal regulatory T cells display distinct migratory behavior that is modulated during adaptive and innate inflammation

The Journal of Immunology

Chow, Z;Mueller, SN;Deane, JA;Hickey, MJ;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Regulatory T cells (Tregs) are important in controlling skin inflammation, an effect dependent on th....

IL-4 and retinoic acid synergistically induce regulatory dendritic cells expressing Aldh1a2

The Journal of Immunology

Zhu, B;Buttrick, T;Bassil, R;Zhu, C;Olah, M;Wu, C;Xiao, S;Orent, W;Elyaman, W;Khoury, SJ;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Although activated inflammatory monocytes (IMCs) and inflammatory dendritic cells (IDCs) are potent ....

Complexity of trophic factor signaling in experimental autoimmune encephalomyelitis: differential expression of neurotrophic and gliotrophic factors

Journal Of Neuroimmunology

Song, F;Bandara, M;Deol, H;Loeb, JA;Benjamins, J;Lisak, RP;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Soluble factors that promote survival and differentiation of glia and neurons during development are....

The antioxidant idebenone fails to prevent or attenuate chronic experimental autoimmune encephalomyelitis in the mouse

Journal Of Neuroimmunology

Fiebiger, SM;Bros, H;Grobosch, T;Janssen, A;Chanvillard, C;Paul, F;Drr, J;Millward, JM;Infante-Duarte, C;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Oxidative stress and mitochondrial dysfunction appear to contribute to neurodegenerative processes d....

Parental dietary fat intake alters offspring microbiome and immunity

Journal of Immunology

Myles IA, Fontecilla NM, Janelsins BM, Vithayathil PJ, Segre JA, Datta SK.

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

Mechanisms underlying modern increases in prevalence of human inflammatory diseases remain unclear. ....

Autoantibody depletion ameliorates disease in murine experimental autoimmune encephalomyelitis

mAbs

Challa, DK;Bussmeyer, U;Khan, T;Montoyo, HP;Bansal, P;Ober, RJ;Ward, ES;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Much data support a role for central nervous system antigen-specific antibodies in the pathogenesis ....

Inhibition of miR-205 impairs the wound-healing process in human corneal epithelial cells by targeting KIR4.1 (KCNJ10)

Investigative Ophthalmology And Visual Science

Lin, D;Halilovic, A;Yue, P;Bellner, L;Wang, K;Wang, L;Zhang, C;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

The aim of the study was to test the hypotheses that injury stimulates the expression of miR-205, wh....

Acrolein-induced activation of mitogen-activated protein kinase signaling is mediated by alkylation of thioredoxin reductase and thioredoxin 1

Redox Biology

Randall, MJ;Spiess, PC;Hristova, M;Hondal, RJ;van der Vliet, A;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

Cigarette smoking remains a major health concern worldwide, and many of the adverse effects of cigar....

Artemisinin analogue SM934 ameliorates murine experimental autoimmune encephalomyelitis through enhancing the expansion and functions of regulatory T cell

PLoS ONE

Li, X;Li, TT;Zhang, XH;Hou, LF;Yang, XQ;Zhu, FH;Tang, W;Zuo, JP;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Artemisinin analogue SM934 was previously reported to possess immunosuppressive properties. The aim ....

The sst1 resistance locus regulates evasion of type I interferon signaling by Chlamydia pneumoniae as a disease tolerance mechanism

PLoS Pathogens

He, X;Berland, R;Mekasha, S;Christensen, TG;Alroy, J;Kramnik, I;Ingalls, RR;

Product: LPS from Escherichia coli O111:B4

The sst1, supersusceptibility to tuberculosis, locus has previously been shown to be a genetic deter....

Central activation of the A1 adenosine receptor (A1AR) induces a hypothermic, torpor-like state in the rat

The Journal of Neuroscience

Tupone, D;Madden, CJ;Morrison, SF;

Product: Anti-Cholera Toxin B Subunit (Goat)

Since central activation of A1 adenosine receptors (A1ARs) plays an important role in the induction ....

NR2B subunit of the NMDA glutamate receptor regulates appetite in the parabrachial nucleus

PNAS

Wu, Q;Zheng, R;Srisai, D;McKnight, GS;Palmiter, RD;

Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae

Diphtheria toxin-mediated, acute ablation of hypothalamic neurons expressing agouti-related protein ....

Protein kinase C as a therapeutic target stabilizing blood-brain barrier disruption in experimental autoimmune encephalomyelitis

PNAS

Lanz, TV;Becker, S;Osswald, M;Bittner, S;Schuhmann, MK;Opitz, CA;Gaikwad, S;Wiestler, B;Litzenburger, UM;Sahm, F;Ott, M;Iwantscheff, S;Grabitz, C;Mittelbronn, M;von Deimling, A;Winkler, F;Meuth, SG;Wick, W;Platten, M;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Disruption of the blood-brain barrier (BBB) is a hallmark of acute inflammatory lesions in multiple ....

Motoneuron BDNF/TrkB signaling enhances functional recovery after cervical spinal cord injury

Experimental Neurology

Mantilla, CB;Gransee, HM;Zhan, WZ;Sieck, GC;

Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

A C2 cervical spinal cord hemisection (SH) interrupts descending inspiratory-related drive to phreni....

A role for the ventral pallidum in context-induced and primed reinstatement of alcohol seeking

European Journal Of Neuroscience

Perry, CJ;McNally, GP;

Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

The ventral pallidum (VP) is a major target of projections from the nucleus accumbens, and has been ....

Prolactin is not required for the development of severe chronic experimental autoimmune encephalomyelitis

The Journal of Immunology

Costanza, M;Musio, S;Abou-Hamdan, M;Binart, N;Pedotti, R;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Predominance of multiple sclerosis (MS) in women, reductions of disease flares during pregnancy, and....

The role of chromogranin B in an animal model of multiple sclerosis

Molecular And Cellular Neuroscience

Mo, M;Hoang, HT;Schmidt, S;Clark, RB;Ehrlich, BE;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Chromogranin B (CGB) is a high capacity, low affinity calcium binding protein in the endoplasmic ret....

Anti-MS4a4B treatment abrogates MS4a4B-mediated protection in T cells and ameliorates experimental autoimmune encephalomyelitis

Apoptosis

Yan, Y;Li, Z;Zhang, GX;Williams, MS;Carey, GB;Zhang, J;Rostami, A;Xu, H;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Recent data show that anti-CD20 therapy is effective for some autoimmune diseases, including multipl....

The MAO inhibitor phenelzine can improve functional outcomes in mice with established clinical signs in experimental autoimmune encephalomyelitis (EAE)

Behavioural Brain Research

Benson, CA;Wong, G;Tenorio, G;Baker, GB;Kerr, BJ;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Many symptoms in multiple sclerosis (MS) can be related to changes in the levels of key neurotransmi....

Transcriptional and post-transcriptional regulation of IB- upon engagement of the BCR, TLRs and FcR

International Immunology

Hanihara, F;Takahashi, Y;Okuma, A;Ohba, T;Muta, T;

Product: LPS from Escherichia coli O111:B4

IB- is a nuclear IB protein robustly induced in macrophages and fibroblasts upon TLR or IL-1R stimul....

Induction of toxin-specific neutralizing immunity by molecularly uniform rice-based oral cholera toxin B subunit vaccine without plant-associated sugar modification

Plant Biotechnology Journal

Yuki, Y;Mejima, M;Kurokawa, S;Hiroiwa, T;Takahashi, Y;Tokuhara, D;Nochi, T;Katakai, Y;Kuroda, M;Takeyama, N;Kashima, K;Abe, M;Chen, Y;Nakanishi, U;Masumura, T;Takeuchi, Y;Kozuka-Hata, H;Shibata, H;Oyama, M;Tanaka, K;Kiyono, H;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

Plants have been used as expression systems for a number of vaccines. However, the expression of vac....

Promotion of colonization and virulence by cholera toxin is dependent on neutrophils

Infection And Immunity

Queen, J;Satchell, KJ;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

The innate immune response to Vibrio cholerae infection is poorly understood, but this knowledge is ....

Enlargement of cerebral ventricles as an early indicator of encephalomyelitis

PLoS ONE

Lepore, S;Waiczies, H;Hentschel, J;Ji, Y;Skodowski, J;Pohlmann, A;Millward, JM;Paul, F;Wuerfel, J;Niendorf, T;Waiczies, S;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Inflammatory disorders of the central nervous system such as multiple sclerosis and acute disseminat....

Expresso de fos aps pulso de escuro no ncleo pr-geniculado do tlamo do sagui (Callithrix jacchus)

Thesis

Lima, RRM;

Product: Anti-Cholera Toxin B Subunit (Goat)

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Bacterial Toxin Terminology

July 23, 2018

By: douano@listlabs.com

By: Mary N. Wessling, Ph.D. ELS In this blog we will unravel the terminology describing bacterial toxins. In general, there are at least three ways that bacterial toxins are described in the literature: by their biological designation—the genus and/or species from which they come by the origin of the toxin, either as innate to the […]

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