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#100B (1 mg)

Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

Info

APOPTOSIS PRODUCT BULLETIN
CHOLERA TOXIN PRODUCT BULLETIN
SIGNAL TRANSDUCTION PRODUCT BULLETIN
COA

Current
Certificate of Testing for Lot# 10071A2
Archived
Certificate of Testing for Lot# 10071A1
Certificate of Analysis for Lot # 10070A1
Certificate of Analysis for Lot # 10069A1
Certificate of Analysis for Lot # 10067A1
Certificate of Analysis for Lot # 10068A1
Certificate of Analysis for Lot # 10060A2
Certificate of Analysis for Lot # 10063A1
SDS

100-sdsv4-128-1-8-pdf-8
Poster

Current
HPLC Method to Assay the ADP-Ribosyltransferase Activity of Cholera Toxin

$375.00

#104 (0.5 mg)

Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

Info

FITC AND BIOTIN CONJUGATES OF CHOLERA TOXIN B SUBUNIT
CHOLERA TOXIN PRODUCT BULLETIN
COA

Current
Certificate of Testing for Lot # 10434A1
Archived
Certificate of Analysis for Lot # 10433A1
Certificate of Analysis for Lot # 10430A1
Certificate of Analysis for Lot # 10431A1
Certificate of Analysis for Lot # 10432A1
Certificate of Analysis for Lot # 10431B1
N-HAZ

non-hazardous-statement-conjugates-129-1-pdf
Poster

Current
HPLC Method to Assay the ADP-Ribosyltransferase Activity of Cholera Toxin

$600.00

#106 (0.2 mg)

Cholera Toxin B Subunit (CTB) from Vibrio cholerae FITC, Conjugate

Info

CHOLERA TOXIN PRODUCT BULLETIN
FITC AND BIOTIN CONJUGATES OF CHOLERA TOXIN B SUBUNIT
COA

Current
Certificate of Analysis for Lot # 10616A v02
Archived
Certificate of Analysis for Lot # 10616A
N-HAZ

non-hazardous-statement-conjugates-12-1-pdf

$300.00

#112 (0.2 mg)

Cholera Toxin B Subunit Biotin Conjugate

Info

CHOLERA TOXIN AND RELATED PRODUCTS
FITC AND BIOTIN CONJUGATES OF CHOLERA TOXIN B SUBUNIT
COA

Current
Certificate of Analysis for Lot # 11212A1
Archived
Certificate of Analysis for Lot # 11211A1
N-HAZ

non-hazardous-statement-conjugates-226-1-pdf

$695.00

#133L (Liquid)

Botulinum Neurotoxin Type A Toxoid from Clostridium botulinum

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 1333A7
Archived
Certificate of Analysis for Lot # 1333A1
Certificate of Analysis for Lot # 1333A3
Certificate of Analysis for Lot # 1333A4
N-HAZ

non-hazardous-statement-toxoids-28-1-pdf

#149A (0.25 mg)

Diphtheria Toxin CRM197, Mutant

Info

DIPHTHERIA TOXIN, TOXOID, CRM MUTANT PRODUCT BULLETIN
Diphtheria Toxin and Engineered Receptor
Protein Carriers for Vaccines
COA

Current
Certificate of Analysis for Lot # 14937A1
Archived
Certificate of Analysis for Lot # 14936A1
Certificate of Analysis for Lot # 14934A1
Certificate of Analysis for Lot # 14935A1
N-HAZ

non-hazardous-statement-v2

$525.00

#150 (1 mg)

Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae

Info

APOPTOSIS PRODUCT BULLETIN
DIPHTHERIA TOXIN, TOXOID, CRM MUTANT PRODUCT BULLETIN
Diphtheria Toxin and Engineered Receptor
Protein Carriers for Vaccines
COA

Current
Certificate of Testing for LoT #15048A1
Archived
Certificate of Analysis for Lot # 15047A1
Certificate of Analysis for Lot # 15046A1
Certificate of Analysis for Lot #15045A1
Certificate of Analysis for Lot # 15042B1
Certificate of Analysis for Lot # 15043A1
SDS

150-sdsv3-35-1-pdf

$783.00

#151 (0.5 mg)

Diphtheria Toxoid, from Corynebacterium diphtheriae

This product is Out of stock.

Info

DIPHTHERIA TOXIN, TOXOID, CRM MUTANT PRODUCT BULLETIN
Diphtheria Toxin and Engineered Receptor
COA

Current
Certificate of Analysis for Lot # 1519A1 v02
Archived
Certificate of Analysis for Lot # 1518A1
N-HAZ

non-hazardous-statement-toxoids-36-1-pdf

#152C (100 ug)

Toxin A from Clostridium difficile

Info

APOPTOSIS PRODUCT BULLETIN
C. DIFFICILE TOXINS PRODUCT BULLETIN
SIGNAL TRANSDUCTION PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Analysis for Lot # 15219A3 v02
Archived
Certificate of Analysis for Lot # 15219A2
Certificate of Analysis for Lot # 15215A1C
Certificate of Analysis for Lot # 15215A5
SDS

152-sdsv3-209-1-pdf

$620.00

#155L (liquid)

Toxin B from Clostridium difficile

Info

APOPTOSIS PRODUCT BULLETIN
C. DIFFICILE TOXINS PRODUCT BULLETIN
SIGNAL TRANSDUCTION PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Testing for Lot #15522A3 v01
Archived
Certificate of Testing for Lot #15522A2 v01
Certificate of Analysis for Lot # 15521G1B
Certificate of Analysis for Lot # 15521G1A
Certificate of Analysis for Lot # 15521A1
Certificate of Analysis for Lot # 15522A1
Certificate of Analysis for Lot # 15518A1A
Certificate of Analysis for Lot # 15520A3A
Certificate of Analysis for Lot # 15520A4A
Certificate of Analysis for Lot # 15520A3B
Certificate of Analysis for Lot # 15521A2
SDS

155-sdsv5-41-1-pdf

$995.00

#156 (50 ug)

Pasteurella multocida Toxin

Info

APOPTOSIS PRODUCT BULLETIN
PASTEURELLA MULTOCIDA TOXIN PRODUCT BULLETIN
SIGNAL TRANSDUCTION PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 1566C1
Archived
Certificate of Analysis for Lot # 1566A1
SDS

156-sdsv3-44-1-pdf

$555.00

#157A (20 ug)

Binary Toxin from Clostridium difficile, A Subunit

This product is discontinued.

Info

C. DIFFICILE TOXINS PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Analysis for Lot # 1573A1
N-HAZ

non-hazardous-statement-other-toxins-201-1-pdf

#159A (0.1 mg)

Glutamate Dehydrogenase (GDH) from Clostridium difficile

This product is discontinued.

Info

C. DIFFICILE TOXINS PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Analysis for Lot # 1591A2
N-HAZ

non-hazardous-statement-other-toxins-222-1-pdf

#161 (10 ug)

Shiga Toxin 1 from Escherichia coli

Info

SHIGA TOXINS Product information
COA

Current
Certificate of Analysis for Lot # 1611A1
SDS

161-sdsv3-174-1-pdf

$600.00

#162L (Liquid)

Shiga Toxin 2 from Escherichia coli

COA

Current
Certificate of Analysis for Lot # 1623A1 v05
Archived
Certificate of Analysis for Lot # 1621A1
Certificate of Analysis for Lot # 1622A1
SDS

162-162l-and-164-sdsv5-176-1-pdf

$955.00

#169L (Liquid)

Anthrax Lethal Factor (LF-A), Recombinant from B. anthracis Native Sequence

Info

MAPKKIDE PLUS PRODUCT BULLETIN
ANTHRAX TOXIN PRODUCT BULLETIN
LETHAL FACTOR, NATIVE SEQUENCE, DESCRIPTION
COA

Current
Certificate of Analysis for Lot # 1694A1
Archived
Certificate of Analysis for Lot # 1692A1B
N-HAZ

non-hazardous-statement-anthrax-toxins-03-15-18-172-1-pdf

$500.00

#170L (Liquid)

Filamentous Hemagglutinin (FHA) from Bordetella pertussis

Info

BORDETELLA VIRULENCE FACTORS PRODUCT INFORMATION
PERTUSSIS TOXIN FROM BORDETELLA PERTUSSIS PRODUCT INFORMATION
SIGNAL TRANSDUCTION PRODUCT BULLETIN
COA

Current
Certificate of Testing for Lot#17056A1
N-HAZ

non-hazardous-statement-other-toxins-158-1-pdf

$450.00

#171E (0.5 mg)

Anthrax Protective Antigen (PA), Recombinant from B. anthracis

Product # 171 is the entire 83 kDa native protein; This product contains the entire anthrax protective antigen 83 kDa native protein.

Info

MAPKKIDE PLUS PRODUCT BULLETIN
ANTHRAX TOXIN PRODUCT BULLETIN
MAPKKIDE PRODUCT BULLETIN
COA

Current
Certificate of Testing for Lot # 17121A2
Archived
Certificate of Analysis for Lot # 17121A1
Certificate of Analysis for Lot # 17120A1
Certificate of Analysis for Lot # 17119A1B
N-HAZ

non-hazardous-statement-anthrax-toxins-210-1-pdf

$770.00

#172B (1 mg), #172L (1 mg),

Anthrax Lethal Factor (LF), Recombinant from B. anthracis

Info

MAPKKIDE PLUS PRODUCT BULLETIN
ANTHRAX TOXIN PRODUCT BULLETIN
MAPKKIDE PRODUCT BULLETIN
COA

Current
172B (1 mg)
Certificate of Analysis for Lot # 1722B15A1 v03
172L (1 mg)
Certificate of Analysis for Lot # 1722B15A2 v03
Archived
172B (1 mg)
Certificate of Analysis for Lot # 1722B10B
172B (1 mg)
Certificate of Analysis for Lot # 1722B11B
172B (1 mg)
Certificate of Analysis for Lot # 17210A1B
172L (1 mg)
Certificate of Analysis for Lot # 1722B15A1
N-HAZ

non-hazardous-statement-anthrax-toxins-53-1-2-pdf-2
Poster

Current
FRET Peptide Substrates for the Botulinum Toxins Type A, B, and E and for Anthrax Lethal Factor
Physical Characteristics of rLF and rPA: Effects on Enzymatic Activity and Binding
Internally Quenched Fluorogenic Substrates for Anthrax Lethal Factor.
Sensitive Detection of Anthrax Lethal Factor in Plasma Using a Specific Biotinylated Fluorogenic Substrate
A Novel Substrate for Specific Detection of Anthrax Infection

$775.00 – $1,025.00

#173B (0.5 mg)

Anthrax Edema Factor (EF), Recombinant, Mutant S447N from B. anthracis

Info

ANTHRAX TOXIN PRODUCT BULLETIN
ADENYLATE CYCLASE TOXIN PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 1732A1
N-HAZ

non-hazardous-statement-anthrax-toxins-56-1-2-pdf-2

$980.00

#174 (0.5 mg)

Anthrax Protective Antigen, Activated (PA 63) from B. anthracis

Product # 174 is PA63, which has been created by enzymatic digestion and purified;

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 17410A1 Rev. 2021
Archived
Certificate of Analysis for Lot # 17410A1
Certificate of Analysis for Lot # 1749A1
Certificate of Analysis for Lot # 17410A1
N-HAZ

non-hazardous-statement-anthrax-toxins-57-1-pdf

$625.00

#175 (50 ug)

Anthrax PA 63 - FITC Conjugate

Product # 175 is purified PA63 conjugated to FITC for visualization.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 1752A1v02
Archived
Certificate of Analysis for Lot # 1751A
N-HAZ

non-hazardous-statement-anthrax-toxins-59-1-pdf

$475.00

#176B (1 mg),

Anthrax Lethal Factor (LF), Recombinant, Mutant E687C from B. anthracis

Info

ANTHRAX TOXIN PROTECTIVE ANTIGEN, LETHAL FACTOR, EDEMA FACTOR From Bacillus anthracis
COA

Current
Certificate of Analysis for Lot # 1761AA Size A
Certificate of Analysis for Lot # 1761AA
N-HAZ

non-hazardous-statement-anthrax-toxins-60-1-pdf

$1,050.00

#177A (50 ug), #177B (.25mg),

Anthrax Protective Antigen Fragment (PA 20) from B. anthracis

Product # 177 is PA20, the approximately 20 kDA fragment cleaved from PA; and

Info
COA

Current
Certificate of Analysis for Lot # 1771A1 v02 Size A
Certificate of Analysis for Lot # 1771A1 v02 Size B
Archived
Certificate of Analysis for Lot # 1771A1 Size A
N-HAZ

non-hazardous-statement-anthrax-toxins-62-1-pdf

$355.00 – $675.00

#178A (0.1 mg)

Anthrax Edema Factor (EF), Recombinant from B. anthracis

Info
COA

Current
Certificate of Analysis for Lot # 1785A1A v02
Archived
Certificate of Analysis for Lot # 1781A1A
Certificate of Analysis for Lot # 1784A1
N-HAZ

non-hazardous-statement-anthrax-toxins-64-1

$205.00

#179A (50 ug)

Pertussis Toxin from B. pertussis (in Glycerol)

Info

PERTUSSIS TOXIN from Bordetella pertussis
SIGNAL TRANSDUCTION product information
COA

Current
Certificate of Testing for Lot#179245A1 v.02
Archived
Certificate of Testing for Lot#179244A1 v02
Certificate of Analysis for Lot # 179227A1A
Certificate of Analysis for Lot # 179216A1A
Certificate of Analysis for Lot # 179216A2A
Certificate of Analysis for Lot # 179202A1A
SDS

179-sdsv4-157-1-pdf

$505.00

#180 (50 ug)

Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Info

PERTUSSIS TOXIN from Bordetella pertussis
SIGNAL TRANSDUCTION product information
COA

Current
Certificate of Testing for Lot # 180248A1
Archived
Certificate of Testing for Lot # 180246A1
Certificate of Testing for Lot # 180245A1
Certificate of Testing for Lot # 180244A3
Certificate of Testing for Lot # 180244A1
Certificate of Testing for Lot # 180243A2 v02
Certificate of Analysis for Lot # 180243A1
Certificate of Analysis for Lot # 180242A1 v02
Certificate of Analysis for Lot # 180241A1
Certificate of Analysis for Lot # 180232A1
Certificate of Analysis for Lot # 180235A1A
SDS

180_181-sdsv5

$500.00

#181 (50 ug)

Pertussis Toxin from B. pertussis, Lyophilized (Salt-Free)

Info

PERTUSSIS TOXIN from Bordetella pertussis
SIGNAL TRANSDUCTION product information
COA

Current
Certificate of Testing for Lot # 1812427A1
Archived
Certificate of Testing for Lot # 181242A2
Certificate of Testing for Lot # 181244A1
Certificate of Testing for Lot # 181242A1 v03
Certificate of Analysis for Lot # 181238A1
Certificate of Analysis for Lot # 181218A1
Certificate of Analysis for Lot # 181220A1
Certificate of Analysis for Lot # 181241A1
Certificate of Analysis for Lot # 181236A1
SDS

180_181-sdsv5

$510.00

#184 (50 ug)

Pertussis Toxin Mutant

This product is discontinued.

Info

PERTUSSIS TOXIN from Bordetella Pertussis
COA

Current
Certificate of Analysis for Lot # 1842A1 v02
N-HAZ

non-hazardous-statement-toxoids-202-1-pdf

#186 (50 ug)

Fimbriae 2/3 from B. pertussis

This product is discontinued.

Info

FIMBRIAE 2/3 FROM BORDETELLA PERTUSSIS
Bordetella Virulence Factors
COA

Current
Certificate of Analysis for Lot # 1865A1
Archived
Certificate of Analysis for Lot # 1863A1
Certificate of Analysis for Lot # 1864C1
N-HAZ

non-hazardous-statement-other-toxins-180-1-pdf

#187 (50 ug)

Pertactin from B. pertussis (69 kDa Protein)

This product is discontinued.

Info

Bordetella Virulence Factors
PERTUSSIS TOXIN from Bordetella pertussis
COA

Current
Certificate of Analysis for Lot # 1876A1 v02
Archived
Certificate of Analysis for Lot # 1874A1
Certificate of Analysis for Lot # 1873A1
Certificate of Analysis for Lot # 1872A1
N-HAZ

non-hazardous-statement-other-toxins-192-1-pdf

#188L (Liquid)

Adenylate Cyclase Toxin, Recombinant from B. pertussis

Info

BORDETELLA VIRULENCE FACTORS PRODUCT INFORMATION
PERTUSSIS TOXIN FROM BORDETELLA PERTUSSIS PRODUCT INFORMATION
ADENYLATE CYCLASE TOXIN PRODUCT BULLETIN
SIGNAL TRANSDUCTION PRODUCT BULLETIN
GENETIC DESCRIPTION
TIPS FOR WORKING WITH ADENYLATE CYCLASE
Adenylate cyclase from B. pertussis, product comparison
COA

Current
Certificate of Testing for Lot # 18810A3
Archived
Certificate of Testing for Lot # 18810A2
Certificate of Analysis for Lot # 18810A1
Certificate of Analysis for Lot # 1889A1
Certificate of Analysis for Lot # 1888A2
Certificate of Analysis for Lot # 1888A3
Certificate of Analysis for Lot # 188L.001
N-HAZ

non-hazardous-statement-other-toxins-158-1-pdf

$505.00

#190A (25 ug), #190B (100 ug),

Tetanus Toxin from Clostridium tetani

Info

TETANUS TOXIN, TETANUS TOXOID, TETANUS LIGHT CHAIN, C-FRAGMENT, FITC C-FRAGMENT AND GST SYNAPTOBREVIN 2 PRODUCT BULLETIN
Protein Carriers for Vaccines
COA

Current
Certificate of Testing for Lot #19050A3
Certificate of Testing for Lot #19050A4
Archived
Certificate of Testing for Lot #19050A3 v02
Certificate of Analysis for Lot # 19050A2
Certificate of Analysis for Lot # 19050A1
Certificate of Analysis for Lot # 19042E1A
Certificate of Analysis for Lot # 19047B1
Certificate of Analysis for Lot # 19042C1
Certificate of Analysis for Lot # 19047A1
SDS

190-sdsv6-73-1-pdf

$300.00 – $870.00

#191A (25 ug), #191B (100 ug),

Tetanus Toxoid from Clostridium tetani

Info

TETANUS TOXIN, TETANUS TOXOID, TETANUS LIGHT CHAIN, C-FRAGMENT, FITC C-FRAGMENT AND GST SYNAPTOBREVIN 2
COA

Current
Certificate of Testing for Lot #19133A5
Certificate of Testing for Lot #19133A3
Certificate of Testing for Lot #19133A4
Archived
Certificate of Testing for Lot # 19133A2
Certificate of Testing for Lot # 19132A2
Certificate of Testing for Lot # 19131A2
Certificate of Testing for Lot # 19132A1 v02
Certificate of Analysis for Lot # 19130A1
Certificate of Analysis for Lot # 19131A1
Certificate of Analysis for Lot # 19127A1
Certificate of Analysis for Lot # 19120A1A
Certificate of Analysis for Lot # 19121A1A
Certificate of Analysis for Lot # 19122A1A
Certificate of Analysis for Lot # 19119A2
Certificate of Analysis for Lot # 19120A1B
Certificate of Analysis for Lot # 19121A1B
Certificate of Analysis for Lot # 19123A1
N-HAZ

non-hazardous-statement-toxoids-75-1-pdf

$460.00 – $1,315.00

#193 (10 ug)

Tetanus Toxin C-Fragment from Clostridium tetani

Info

TETANUS TOXIN, TETANUS TOXOID, TETANUS LIGHT CHAIN, C-FRAGMENT, FITC C-FRAGMENT AND GST SYNAPTOBREVIN 2
COA

Current
Certificate of Analysis for Lot # 19313C1
N-HAZ

non-hazardous-statement-conjugates-77-1-pdf

$750.00

#196A (10 ug)

Tetanus Toxin C-Fragment from Clostridium tetani, FITC Conjugate

This product is discontinued.

COA

Current
Certificate of Analysis for Lot # 1963A1
N-HAZ

non-hazardous-statement-conjugates-78-1-pdf

#201 (5 mg)

LPS from Escherichia coli O111:B4

Info

APOPTOSIS PRODUCT BULLETIN
HIGHLY PURIFIED BACTERIAL LPS PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 20148A1, V2
Archived
Certificate of Testing for Lot # 20147A2
Certificate of Analysis for Lot # 20147A1
Certificate of Analysis for Lot # 20146A1
Certificate of Analysis for Lot # 20144A2
Certificate of Analysis for Lot # 20146A1
Certificate of Analysis for Lot # 20146A2
SDS

201-sdsv1-81-1-pdf

$325.00

#203A (2.5 mg)

LPS from Escherichia coli O55:B5

Info

HIGHLY PURIFIED BACTERIAL LPS PRODUCT BULLETIN
APOPTOSIS PRODUCT BULLETIN
COA

Current
Certificate of Testing for Lot # 20327A4
Certificate of Testing for Lot # 20327A2
Archived
Certificate of Testing for Lot # 20328A1
Certificate of Testing for Lot # 20326A2 v03
Certificate of Testing for Lot # 20326B2 v02
Certificate of Analysis for Lot # 20324A1
Certificate of Analysis for Lot # 20323B1
Certificate of Analysis for Lot # 20323B2
Certificate of Analysis for Lot # 20321A6
SDS

203-sdsv1-82-1-pdf

$360.00

#225 (5 mg)

LPS from Salmonella typhimurium

Info

HIGHLY PURIFIED BACTERIAL LIPOPOLYSACCHARIDES AND RELATED PRODUCTS
APOPTOSIS PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 2258A2
Archived
Certificate of Analysis for Lot # 2258A1
SDS

225-sdsv1-85-1-pdf

$220.00

#301 (5 mg)

LPS from Escherichia coli J5 (Rc)

This product is discontinued.

Info

HIGHLY PURIFIED BACTERIAL LIPOPOLYSACCHARIDES AND RELATED PRODUCTS
APOPTOSIS PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 30131A1
Archived
Certificate of Analysis for Lot # 30130A1
Certificate of Analysis for Lot # 30130A2
SDS

301-sdsv1-86-1-pdf

#302 (5 mg)

LPS from Escherichia coli K12, D31m4 (Re)

Info

HIGHLY PURIFIED BACTERIAL LIPOPOLYSACCHARIDES AND RELATED PRODUCTS
APOPTOSIS PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 3029A1 v03
Archived
Certificate of Analysis for Lot # 3027A1
SDS

302-sdsv1-87-1-pdf

$200.00

#304 (5 mg)

LPS from Salmonella minnesota R595 (Re)

Info

HIGHLY PURIFIED BACTERIAL LIPOPOLYSACCHARIDES AND RELATED PRODUCTS
APOPTOSIS PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 30448A1
Archived
Certificate of Analysis for Lot # 30446A1
SDS

304-sdsv1-88-1-pdf

$220.00

#314 (1 mg)

LPS from Escherichia coli K12 strain LCD25

Info

HIGHLY PURIFIED BACTERIAL LIPOPOLYSACCHARIDES AND RELATED PRODUCTS
COA

Current
Certificate of Analysis for Lot # 3141C1 v02
SDS

314-sdsv1-89-1-pdf

$200.00

#401 (1 mg)

LIPID A monophosphoryl from Salmonella minnesota R595

Info

HIGHLY PURIFIED BACTERIAL LIPOPOLYSACCHARIDES AND RELATED PRODUCTS
COA

Current
Certificate of Analysis for Lot # 40140A1
Archived
Certificate of Analysis for Lot # 40138A
Certificate of Analysis for Lot # 40139A1
SDS

non-hazardous-statement-lps-and-related-91-1-pdf

$240.00

#421 (1 mg)

ULTRA PURE LPS from Escherichia coli O111:B4

This product is discontinued.

Info

HIGHLY PURIFIED BACTERIAL LIPOPOLYSACCHARIDES AND RELATED PRODUCTS
COA

Current
Certificate of Analysis for Lot # 4219A1
Archived
Certificate of Analysis for Lot # 4216A3
Certificate of Analysis for Lot # 4217A1
Certificate of Analysis for Lot # 4218A1
Certificate of Analysis for Lot # 4218A1
SDS

421-sdsv1-92-1-pdf

#423 (1 mg)

ULTRA PURE LPS from Escherichia coli O55:B5

This product is discontinued.

Info

HIGHLY PURIFIED BACTERIAL LIPOPOLYSACCHARIDES AND RELATED PRODUCTS
COA

Current
Certificate of Analysis for Lot # 4231A1
SDS

423-sdsv1-123-1-pdf

#433 (1 mg)

LIST™ HPT™ from Escherichia coli O113

This product is discontinued.

Info

HIGHLY PURIFIED BACTERIAL LIPOPOLYSACCHARIDES AND RELATED PRODUCTS
COA

Current
Certificate of Analysis for Lot # 4331B1 v03
SDS

433-sdsv1-193-1-pdf

#434 (1 mg)

ULTRA PURE LPS from Salmonella minnesota R595 (Re)

Info

APOPTOSIS PRODUCT BULLETIN
HIGHLY PURIFIED BACTERIAL LPS PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 4345A1
Archived
Certificate of Analysis for Lot # 4343A1
Certificate of Analysis for Lot # 4345A1
SDS

434-sdsv1-93-1-pdf

$285.00

#500A (100 ug)

SNAP-25 Recombinant Protein Substrate for C. botulinum Types A and E Neurotoxin

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 5004A1 v02
Archived
Certificate of Analysis for Lot # 5003A1
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-96-1-pdf

$410.00

#520 (200 nmoles)

SNAPtide® Peptide Substrate (o-Abz/Dnp) for C. botulinum Type A Neurotoxin

Info

BOTULINUM NEUROTOXINS PRODUCT BULLETIN
SNAPTIDE, VAMPTIDE, SYNTAXTIDE, AND SNAP ETIDE PRODUCT BULLETIN
COA

Current
Certificate of Testing for Lot 52011A1
Certificate of Testing for Lot 52010A2
Archived
Certificate of Testing for Lot 52010A1
Certificate of Testing for Lot # 5209A5 v01
Certificate of Analysis for Lot # 5209A4 v01
Certificate of Analysis for Lot # 5209A2
Certificate of Analysis for Lot # 5209A1
Certificate of Analysis for Lot # 5209A3
Certificate of Analysis for Lot # 5108A1
Certificate of Analysis for Lot # 5208A3
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-98-1-pdf
Poster

Current
SENSITIVE DETECTION OF BOTULINUM NEUROTOXIN TYPE A USING HIGH AFFINITY POLYCLONAL ANTIBODIES
Comparison of Activity of Botulinum Neurotoxin Type A Holotoxin and Light Chain Using SNAPtide ® FRET Substrates
FRET peptide substrates for the Botulinum toxins type A, B, and E and for anthrax lethal factor
Capture Assay for Botulinum Neurotoxin Type A Utilizing the Neuronal Receptor Protein SV2c
Functional Assay for Botulinum Neurotoxin Type A Utilizing the Neuronal Receptor Protein SV2c
Sensitive, In Vitro, Bifunctional, Potency Assay For Botulinum Neurotoxin Type A
FRET Peptide Substrates for Botulinum Neurotoxins Types A, B, C, and E
EVALUATION OF A SMALL PEPTIDE INHIBITOR AND A CONTROL PEPTIDE FOR BOTULINUM NEUROTOXIN, TYPE A
ULTRA SENSITIVE HPLC DETECTION ASSAY FOR BOTULINUM NEUROTOXIN TYPE A
NEW SV2c CONSTRUCT FOR USE IN BINDING AND DETECTING BOUTULINUM NEUROTOXIN TYPE A
SENSITIVE AND SPECIFIC BIFUNCTIONAL ASSAY FOR BOTULINUM NEUROTOXIN TYPE A

$970.00

#521 (200 nmoles)

SNAPtide® Peptide Substrate (FITC/DABCYL) for C. botulinum Type A Neurotoxin

This product is discontinued.

Info

BOTULINUM NEUROTOXINS PRODUCT BULLETIN
SNAPTIDE, VAMPTIDE, SYNTAXTIDE, AND SNAP ETIDE PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 5214A3 v02
Archived
Certificate of Analysis for Lot # 5213A2
Certificate of Analysis for Lot # 5214A2
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-99-1-pdf
Poster

Current
EVALUATION OF A SMALL PEPTIDE INHIBITOR AND A CONTROL PEPTIDE FOR BOTULINUM NEUROTOXIN, TYPE A
FRET Peptide Substrates for Botulinum Neurotoxins Types A, B, C, and E
Comparison of Activity of Botulinum Neurotoxin Type A Holotoxin and Light Chain Using SNAPtide ® FRET Substrates
NEW FRET SUBSTRATE FOR BOTULINUM NEUROTOXIN TYPE A
FRET peptide substrates for the Botulinum toxins type A, B, and E and for anthrax lethal factor

#523 (200 nmoles)

SNAPtide® Peptide Substrate flP6(DABCYL/5-IAF) for C. botulinum Type A Neurotoxin

Info

BOTULINUM NEUROTOXINS
COA

Current
Certificate of Analysis for Lot # 5232A1 v02
Archived
Certificate of Analysis for Lot # 5231A1
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-183-1
Poster

Current
NEW FRET SUBSTRATE FOR BOTULINUM NEUROTOXIN TYPE A

$600.00

#525 (200 nmoles)

Control Peptide for SNAPtide® 520 Substrate for C. botulinum Type A Neurotoxin

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 5252A1 v02
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-169-1-pdf
Poster

Current
EVALUATION OF A SMALL PEPTIDE INHIBITOR AND A CONTROL PEPTIDE FOR BOTULINUM NEUROTOXIN, TYPE A

$600.00

#526 (200 nmoles)

Control Peptide for SNAPtide® 521 for C. botulinum Type A Neurotoxin

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 5261A1 v02
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-186-1-pdf

$600.00

#528 (50 nmoles)

Unquenched Calibration Peptide for SNAPtide® 521 Substrate for C. botulinum Type A Neurotoxin

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 5281A2
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-100-1-pdf
Poster

Current
NEW FRET SUBSTRATE FOR BOTULINUM NEUROTOXIN TYPE A
Comparison of Activity of Botulinum Neurotoxin Type A Holotoxin and Light Chain Using SNAPtide ® FRET Substrates

#529 (50 nmoles)

Unquenched Calibration Peptide for SNAPtide® 520 Substrate for C. botulinum Type A Neurotoxin

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 5292A2 v02
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-101-1-pdf
Poster

Current
SENSITIVE AND SPECIFIC BIFUNCTIONAL ASSAY FOR BOTULINUM NEUROTOXIN TYPE A
Comparison of Activity of Botulinum Neurotoxin Type A Holotoxin and Light Chain Using SNAPtide ® FRET Substrates

$250.00

#530 (200 nmoles)

MAPKKide® Peptide Substrate (o-Abz/Dnp) for Anthrax Lethal Factor

Product # 530 is MAPKKide® utilizing the o-Abz/Dnp FRET pair. A calibration peptide, Product #539 is available for convenient use with the quenched substrate.

Info

MAPKKIDE PLUS PRODUCT BULLETIN
ANTHRAX TOXIN PRODUCT BULLETIN
MAPKKIDE PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 5303A6
Certificate of Analysis for Lot # 5303A5
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-102-1-pdf
Poster

Current
Internally Quenched Fluorogenic Substrates for Anthrax Lethal Factor
Physical Characteristics of rLF and rPA: Effects on Enzymatic Activity and Binding
FRET Peptide Substrates for the Botulinum Toxins Type A, B, and E and for Anthrax Lethal Factor

$365.00

#531 (200 nmoles)

MAPKKide® Peptide Substrate (DABCYL/FITC) for Anthrax Lethal Factor

This product is discontinued.Product # 531 is MAPKKide® with the FRET pair DABCYL/FITC.

Info

MAPKKIDE PLUS PRODUCT BULLETIN
ANTHRAX TOXIN PRODUCT BULLETIN
MAPKKIDE PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 5313A1
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-103-1-pdf
Poster

Current
FRET peptide substrates for the Botulinum toxins type A, B, and E and for anthrax lethal factor

#532 (100 nmoles)

MAPKKide® Plus (AMC) Specific Substrate for Anthrax Lethal Factor

Product # 532 is MAPKKide® Plus Specific Substrate for Anthrax Lethal Factor. This peptide is remarkable in its resistance to non-specific cleavage by enzymes which may be present in natural samples. MAPKKide® Plus carries the fluorophore 7-amido-4-methylcoumarin (AMC).

Info

MAPKKIDE PRODUCT BULLETIN
MAPKKIDE PLUS PRODUCT BULLETIN
ANTHRAX TOXIN PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 5321A1
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-251-1-pdf
Poster

Current
Sensitive Detection of Anthrax Lethal Factor in Plasma Using a Specific Biotinylated Fluorogenic Substrate
MAPKKide® Plus: A Specific Substrate for Sensitive Detection of Anthrax Lethal Factor in Complex Matrices
Fluorescence Substrate for Specific and Quantitative Detection of Anthrax Lethal Factor in Plasma
Substrate for Specific Lethal Factor
Specific Detection of Anthrax Infection

$305.00

#539 (50 nmoles)

Unquenched Calibration Peptide for MAPKKide® 530 for Anthrax Lethal Factor

This product is discontinued.

Info

MAPKKIDE PLUS PRODUCT BULLETIN
ANTHRAX TOXIN PRODUCT BULLETIN
MAPKKIDE PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 5391A2
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-104-1-pdf
Poster

Current
Physical Characteristics of rLF and rPA: Effects on Enzymatic Activity and Binding

#540 (200 nmoles)

VAMPtide® Peptide Substrate (o-Abz/Dnp) Substrate for C. botulinum Type B Neurotoxin

This product is discontinued.

Info

BOTULINUM NEUROTOXINS PRODUCT BULLETIN
SNAPTIDE, VAMPTIDE, SYNTAXTIDE, AND SNAP ETIDE PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 5404A1
Archived
Certificate of Analysis for Lot # 5403A1
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-105-1-pdf
Poster

Current
EVALUATION OF THREE VAMPTIDE® SUBSTRATES FOR BOTULINUM NEUROTOXIN TYPE B
FRET Peptide Substrates for Botulinum Neurotoxins Types A, B, C, and E
FRET peptide substrates for the Botulinum toxins type A, B, and E and for anthrax lethal factor
Comparison of Activity of Botulinum Neurotoxin Type A Holotoxin and Light Chain Using SNAPtide ® FRET Substrates

#541 (200 nmoles)

VAMPtide® Peptide Substrate (FITC/DABCYL) Substrate for C. botulinum Type B Neurotoxin

Info

BOTULINUM NEUROTOXINS PRODUCT BULLETIN
SNAPTIDE, VAMPTIDE, SYNTAXTIDE, AND SNAP ETIDE PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 5411A1 v02
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-170-1-pdf
Poster

Current
EVALUATION OF THREE VAMPTIDE® SUBSTRATES FOR BOTULINUM NEUROTOXIN TYPE B

$600.00

#542 (200 nmoles)

VAMPtide® (Pya/Nop) Peptide Substrate for Botulinum Neurotoxin Type B

Info

BOTULINUM NEUROTOXINS
FRET Peptides Native Substrates and Receptors
COA

Current
Certificate of Analysis for Lot # 5421A1
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-190-1-pdf
Poster

Current
EVALUATION OF THREE VAMPTIDE® SUBSTRATES FOR BOTULINUM NEUROTOXIN TYPE B

$600.00

#549 (100 nmoles)

Calibration Fluorophore for VAMPtide® 540 Substrate for C. botulinum Type B Neurotoxin

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 5491A1
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-147-1-pdf

$205.00

#550 (100 nmoles)

SNAP Etide® Peptide Substrate (o-Abz/Dnp) for C. botulinum Type E Neurotoxin

This product is discontinued.

Info

BOTULINUM NEUROTOXINS PRODUCT BULLETIN
SNAPTIDE, VAMPTIDE, SYNTAXTIDE, AND SNAP ETIDE PRODUCT BULLETIN
COA

Archived
Certificate of Testing for Lot # 5504A1
Certificate of Analysis for Lot # 5503A1 v02
Certificate of Analysis for Lot # 5502A1
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-106-1-pdf
Poster

Current
FRET Peptide Substrates for Botulinum Neurotoxins Types A, B, C, and E
SNAP EtideTM, a FRET Substrate for BotulinumToxin Type E
FRET peptide substrates for the Botulinum toxins type A, B, and E and for anthrax lethal factor

#559 (50 nmoles)

Unquenched Calibration Peptide for SNAP Etide® Prod #550

COA

Current
Certificate of Analysis for Lot # 5591A1 v02
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-256-1-pdf

$290.00

#560 (200 nmoles)

SYNTAXtide® (o-Abz/Dnp) Peptide Substrate for C. botulinum Type C Neurotoxin

Info

BOTULINUM NEUROTOXINS PRODUCT BULLETIN
SNAPTIDE, VAMPTIDE, SYNTAXTIDE, AND SNAP ETIDE PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 5602A1
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-144-1-pdf
Poster

Current
Ultra Sensitive HPLC Detection Assay for Botulinum Neurotoxin Type A
FRET Peptide Substrates for Botulinum Neurotoxins Types A, B, C, and E

$555.00

#611A (15 ug)

Botulinum Neurotoxin Type A Light Chain, Recombinant, GST Fusion

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 6112A1
Archived
Certificate of Analysis for Lot # 6111A1
N-HAZ

non-hazardous-statement-recombinant-chains-23-1-pdf

$310.00

#612A (50 ug)

Botulinum Neurotoxin Type A Heavy Chain, Recombinant, Binding Domain

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 6123A1
Archived
Certificate of Analysis for Lot # 6121A1
Certificate of Analysis for Lot # 6122A1
N-HAZ

non-hazardous-statement-recombinant-chains-153-1-pdf
Poster

Current
New High Affinity Antibodies Against Botulinum Neurotoxin Type A

#613A (50 ug)

Botulinum Neurotoxin Type A Heavy Chain, Recombinant, Binding Domain, GST Fusion

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 6131B1
N-HAZ

non-hazardous-statement-recombinant-chains-149-1-pdf

#620A (10 ug)

Botulinum Neurotoxin Type B Light Chain, Recombinant

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 62015A1
Archived
Certificate of Analysis for Lot # 6206A1
N-HAZ

non-hazardous-statement-recombinant-chains-24-1-pdf
Poster

Current
EVALUATION OF THREE VAMPTIDE® SUBSTRATES FOR BOTULINUM NEUROTOXIN TYPE B
FRET Peptide Substrates for Botulinum Neurotoxins Types A, B, C, and E
Comparison of Activity of Botulinum Neurotoxin Type A Holotoxin and Light Chain Using SNAPtide ® FRET Substrates

$555.00

#622A (50 ug)

Botulinum Neurotoxin Type B Heavy Chain, Recombinant, Binding Domain

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 6222A1
Archived
Certificate of Analysis for Lot # 6221A1
N-HAZ

non-hazardous-statement-recombinant-chains-152-1-pdf

#623A (50 ug)

Botulinum Neurotoxin Type B Heavy Chain, Recombinant, Binding Domain, GST Fusion

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 6231A1
N-HAZ

non-hazardous-statement-recombinant-chains-150-1-pdf

#625A (10 ug)

Botulinum Neurotoxin Type C Light Chain, Recombinant

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 6256A1
Archived
Certificate of Analysis for Lot # 6253A1
N-HAZ

non-hazardous-statement-recombinant-chains-25-1-pdf
Poster

Current
FRET Peptide Substrates for Botulinum Neurotoxins Types A, B, C, and E
Ultra Sensitive HPLC Detection Assay for Botulinum Neurotoxin Type A

$555.00

#630A (10 ug)

Botulinum Neurotoxin Type D Light Chain, Recombinant

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 6301A1 v02
N-HAZ

non-hazardous-statement-recombinant-chains-26-1-pdf

#690B (100 ug)

Receptor for Clostridium botulinum Type A Neurotoxin, GST-SV2c luminal domain

This product is discontinued.

Info

Technical Info
COA

Archived
Certificate of Testing for Lot # 6906A1
Certificate of Analysis for Lot # 6905A1
Certificate of Analysis for Lot # 6904A1
Certificate of Analysis for Lot # 6902A1
N-HAZ

non-hazardous-statement-recombinant-chains-194-1-pdf
Poster

Current
SENSITIVE AND SPECIFIC BIFUNCTIONAL ASSAY FOR BOTULINUM NEUROTOXIN TYPE A
Ultra Sensitive HPLC Detection Assay for Botulinum Neurotoxin Type A
Functional Assay for Botulinum Neurotoxin Type A Utilizing the Neuronal Receptor Protein SV2c
Capture Assay for Botulinum Neurotoxin Type A Utilizing the Neuronal Receptor Protein SV2c
Sensitive, In Vitro, Bifunctional, Potency Assay For Botulinum Neurotoxin Type A

#703 (0.1 ml)

Anti-Cholera Toxin B Subunit (Goat)

Info

FITC AND BIOTIN CONJUGATES OF CHOLERA TOXIN B SUBUNIT
CHOLERA TOXIN PRODUCT BULLETIN
COA

Current
Certificate of Testing for Lot # 7032A12
Certificate of Testing for Lot # 7032A11
Archived
Certificate of Analysis for Lot # 7032A10
Certificate of Analysis for Lot # 7032A9
Certificate of Analysis for Lot # 7032A6
Certificate of Analysis for Lot # 7032A7
Certificate of Analysis for Lot # 7032A8
N-HAZ

non-hazardous-statement-antisera-and-antibodies-110-1-pdf

$320.00

#730A (0.1 mg)

Anti-Botulinum Neurotoxin, Type A (Chicken lgY)

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Testing for Lot # 7304A1
Archived
Certificate of Analysis for Lot # 7303A1
Certificate of Analysis for Lot # 7302A1
Certificate of Analysis for Lot # 7302B2
Certificate of Analysis for Lot # 7302A1
N-HAZ

non-hazardous-statement-antisera-and-antibodies-140-1-pdf
Poster

Current
New High Affinity Antibodies Against Botulinum Neurotoxin Type A
SENSITIVE DETECTION OF BOTULINUM NEUROTOXIN TYPE A USING HIGH AFFINITY POLYCLONAL ANTIBODIES

#731L (0.1 mg)

Anti-Botulinum Neurotoxin, Type A (Mouse lgG monoclonal F1-40), Frozen Liquid

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 7311A2 v02
N-HAZ

non-hazardous-statement-antisera-and-antibodies-197-1-pdf
Poster

Current
New High Affinity Antibodies Against Botulinum Neurotoxin Type A
ULTRA SENSITIVE HPLC DETECTION ASSAY FOR BOTULINUM NEUROTOXIN TYPE A

$435.00

#752 (0.5 ml)

Anti-Toxin A from Clostridium difficile (Goat)

This product is discontinued.

Info

C. DIFFICILE TOXINS PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Analysis for Lot # 7521A2 v02
Archived
Certificate of Analysis for Lot # 7521A
N-HAZ

non-hazardous-statement-antisera-and-antibodies-111-1-pdf

#753A (0.1 mg)

Anti-Clostridium difficile Toxin A (Chicken lgY)

This product is discontinued.

Info

C. DIFFICILE TOXINS PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Analysis for Lot # 7531A2
Archived
Certificate of Analysis for Lot # 7531A1
N-HAZ

non-hazardous-statement-antisera-and-antibodies-160-1-pdf

#754A (0.1 mg)

Anti-Clostridium difficile Toxin B (Chicken lgY)

This product is discontinued.

Info

C. DIFFICILE TOXINS PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Analysis for Lot # 7542A1
N-HAZ

non-hazardous-statement-antisera-and-antibodies-196-1-pdf

#756A (0.1 mg)

Anti-Glutamate Dehydrogenase from Clostridium difficile lgY

This product is discontinued.

Info

C. DIFFICILE TOXINS PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Analysis for Lot # 7561A2
N-HAZ

non-hazardous-statement-antisera-and-antibodies-223-1-pdf

#757A (0.1 mg)

Anti-Clostridium difficile Binary Toxin A subunit (Chicken lgY)

This product is discontinued.

Info

C. DIFFICILE TOXINS PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Analysis for Lot # 7572A1
Archived
Certificate of Analysis for Lot # 7571A1
N-HAZ

non-hazardous-statement-antisera-and-antibodies-221-1-pdf

#758A (0.1 mg)

Anti-Clostridium difficile Binary Toxin B Subunit (Chicken lgY)

This product is discontinued.

Info

C. DIFFICILE TOXINS PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Analysis for Lot # 7582A1
Archived
Certificate of Analysis for Lot # 7581A1
N-HAZ

non-hazardous-statement-antisera-and-antibodies-212-1-pdf

#759A (0.1 mg)

Biotinylated Anti-Clostridium difficile Binary Toxin B Subunit (Chicken lgY)

This product is discontinued.

Info

C. DIFFICILE TOXINS PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Analysis for Lot # 7591A1
N-HAZ

non-hazardous-statement-antisera-and-antibodies-213-1-pdf

#761L (Liquid)

Anti-Shiga Toxin 1, Rabbit lgG

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 7611A1
N-HAZ

non-hazardous-statement-antisera-and-antibodies-248-1-pdf

#766L (Liquid)

Anti-Shiga Toxin, Camelid Antibody, VHH

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 7661A1
N-HAZ

non-hazardous-statement-antisera-and-antibodies-246-1-pdf

#768L (Liquid)

Anti-B. anthracis Lethal Factor (LF-A), lgY Antibody, Biotinylated

Product # 768L affinity purified and biotinylated Anti-Lethal Factor from B. anthracis (chicken lgY) works to detect the LF as described in the C of A.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 7681A1
N-HAZ

non-hazardous-statement-antisera-and-antibodies-245-1-pdf

$415.00

#771B (1 mg)

Anti-Protective Antigen from B. anthracis (Goat)

This product is discontinued.Products # 771, purified IgG from goat, is directed to PA.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 7712A3
Certificate of Analysis for Lot # 7712A2
Archived
Certificate of Analysis for Lot # 7711A6
Certificate of Analysis for Lot # 7712A1
N-HAZ

non-hazardous-statement-antisera-and-antibodies-115-1-pdf

#773L (Liquid)

Anti-Edema Factor from B. anthracis (Goat)

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 7732A3
N-HAZ

non-hazardous-statement-antisera-and-antibodies-117-1-pdf

The phosphatase DUSP22 inhibits UBR2-mediated K63-ubiquitination and activation of Lck downstream of TCR signalling

Nature Communications

Shih, YC;Chen, HF;Wu, CY;Ciou, YR;Wang, CW;Chuang, HC;Tan, TH;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

DUSP22 is a dual-specificity phosphatase that inhibits T cell activation by inactivating the kinase ....

Upregulation of CD8+ regulatory T cells following liver-directed AAV gene therapy

Cellular Immunology

Gaddie, CD;Senior, KG;Chan, C;Hoffman, BE;Keeler, GD;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Liver-directed AAV gene therapy represents a unique treatment modality for a host of diseases. This ....

Synaptic input and Ca2+ activity in zebrafish oligodendrocyte precursor cells contribute to myelin sheath formation

Nature Neuroscience

Li, J;Miramontes, TG;Czopka, T;Monk, KR;

Product: Tetanus Toxin from Clostridium tetani

In the nervous system, only one type of neuron-glial synapse is known to exist: that between neurons....

PTEN inhibition promotes robust growth of bulbospinal respiratory axons and partial recovery of diaphragm function in a chronic model of cervical contusion spinal cord injury

Biorxiv : The Preprint Server For Biology

Michel-Flutot, P;Cheng, L;Thomas, SJ;Lisi, B;Schwartz, H;Lam, S;Lyttle, M;Jaffe, DA;Smith, G;Li, S;Wright, MC;Lepore, AC;

Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

High spinal cord injury (SCI) leads to persistent and debilitating compromise in respiratory functio....

Foxo1 drives the TGFβ1-dependent dichotomy of Th17 cell fates

Journal Of Leukocyte Biology

Zhang, M;Guan, Y;Han, M;Kong, F;Xu, A;Jin, X;Hu, X;Dong, F;Zhang, N;Peng, X;Liu, D;Chen, Y;Zhao, R;Zhu, X;Zhang, Y;Lu, C;Hou, W;Liu, L;Li, D;Zhang, Z;Zhang, X;Zhang, S;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

T-helper 17 cells play a dual role in immunological responses, serving as essential components in ti....

Paracrine signalling by pancreatic ? cells determines the glycaemic set point in mice

Nature Metabolism

Huang, J;Pourhosseinzadeh, M;Lee, S;Krämer, N;Guillen, J;Cinque, N;Aniceto, P;Momen, A;Koike, S;Huising, M;

Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae

Multimodal vaccination targeting the receptor binding domains of Clostridioides difficile toxins A and B with an attenuated Salmonella Typhimurium vector (YS1646) protects mice from lethal challenge

Microbiology Spectrum

Winter, K;Houle, S;Dozois, CM;Ward, BJ;

Product: Toxin A from Clostridium difficile

Clostridioides difficile remains a major public health threat, and new approaches are needed to deve....

Curcumin and Its Semisynthetic Derivative F-Curcumin Ameliorate the Expression of Cytokines in Autoimmune Encephalomyelitis Mouse Models of Multiple Sclerosis

Iranian Journal Of Allergy, Asthma And Immunology

Khosropour, S;Shahvarooghi, E;Rezaeizadeh, H;Esmaeelzadeh, M;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Multiple sclerosis (MS) is an inflammatory disorder impacting the central nervous system, with cytok....

Disease-associated astrocyte epigenetic memory promotes CNS pathology

Biorxiv : The Preprint Server For Biology

Lee, HG;Rone, JM;Li, Z;Akl, CF;Shin, SW;Lee, JH;Flausino, LE;Pernin, F;Chao, CC;Kleemann, KL;Srun, L;Illouz, T;Giovannoni, F;Charabati, M;Sanmarco, LM;Kenison, JE;Piester, G;Zandee, SEJ;Antel, J;Rothhammer, V;Wheeler, MA;Prat, A;Clark, IC;Quintana, FJ;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Astrocytes play important roles in the central nervous system (CNS) physiology and pathology. Indeed....

Coexpressed?-,?-, and?-Opioid Receptors Modulate Voltage-Gated Ca2+Channels in Gastric-Projecting Vagal Afferent Neurons

Molecular Pharmacology

Goudsward, H;Ruiz?Velasco, V;Stella, S;Willing, L;Holmes, G;

Product: Pertussis Toxin from B. pertussis, Lyophilized (Salt-Free)

Opioid analgesics are frequently associated with gastrointestinal side effects, including constipati....

Autoimmune demyelination alters hypothalamic transcriptome and endocrine function

Journal Of Neuroinflammation

Carver, JJ;Lau, KM;Puckett, AE;Didonna, A;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

The hypothalamus is a brain structure that is deputed to maintain organism homeostasis by regulating....

Gasdermin D in macrophages drives orchitis by regulating inflammation and antigen presentation processes

EMBO Molecular Medicine

Ma, C;Huang, J;Jiang, Y;Liu, L;Wang, N;Huang, S;Li, H;Zhang, X;Wen, S;Wang, B;Yang, S;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Inflammation in the testes induced by infection and autoimmunity contributes significantly to male i....

Direct interrogation of context-dependent GPCR activity with a universal biosensor platform

Biorxiv : The Preprint Server For Biology

Janicot, R;Maziarz, M;Park, JC;Luebbers, A;Green, E;Zhao, J;Philibert, C;Zhang, H;Layne, MD;Wu, JC;Garcia-Marcos, M;

Product: Pertussis Toxin from B. pertussis (in Glycerol)

G protein-coupled receptors (GPCRs) are the largest family of druggable proteins in the human genome....

Exposure to Mycobacterium remodels alveolar macrophages and the early innate response to Mycobacterium tuberculosis infection

PLOS Pathogens

Mai, D;Jahn, A;Murray, T;Morikubo, M;Lim, PN;Cervantes, MM;Pham, LK;Nemeth, J;Urdahl, K;Diercks, AH;Aderem, A;Rothchild, AC;

Product: LPS from Salmonella minnesota R595 (Re)

Alveolar macrophages (AMs) play a critical role during Mycobacterium tuberculosis (Mtb) infection as....

The antioxidant N-acetyl cysteine inhibits cytokine and prostaglandin release in human fetal membranes stimulated ex vivo with lipoteichoic acid or live group B streptococcus

American Journal Of Reproductive Immunology

Park, HR;Harris, SM;Boldenow, E;Aronoff, DM;Rea, M;Xi, C;Loch-Caruso, R;

Product: LPS from Salmonella typhimurium

Infection during pregnancy is a significant public health concern due to the increased risk of adver....

Luminespib inhibitor

Luminespibinhibitor.Com

OHTA, H;SATO, K;MURATA, N;DAMIRIN, A;MALCHINKHUU, E;KON, J;KIMURA, T;TOBO, M;YAMAZAKI, Y;WATANABE, T;YAGI, M;SATO, M;SUZUKI, R;MUROOKA, H;SAKAI, T;NISHITOBA, T;IM, D;NOCHI, H;TAMOTO, K;TOMURA, H;OKAJIMA, F;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Lysophosphatidic acid (LPA) exerts a variety of biological re- sponses through specific receptors: t....

Investigation of brain extracellular matrix and application of experimental MRI to understand disease development in a murine model of multiple sclerosis

Thesis

Vieira da Silva, R;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Multiple sclerosis (MS) is a chronic neuroimmunological disease with growing incidence in which auto....

Biomechanical investigation of neurogenesis and neuroinflammation in the mouse brain by elastography

Thesis

Morr, A;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Investigation of the brain´s biomechanical properties provides information on its function in physio....

Effect of human complement proteins on the activity of binary bacterial toxins of Clostridium botulinum and Bacillus anthracis

Thesis

Wohlfart, J;

Product: Anthrax Lethal Factor (LF), Recombinant from B. anthracis

C2 toxin from Clostridium botulinum and lethal toxin from Bacillus anthracis are both composed of an....

Novel Insights into the Autoimmune Mechanisms in Coxsackievirus B Infections and Their Prevention by Vaccination

Thesis

Rasquinha, MT;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Coxsackievirus Bs (CVBs) are RNA viruses of the genus Enterovirus belonging to the Picornaviridae fa....

The signaling pathways of lipopolysaccharides and monophosphoryl lipid A in M1 and M2 macrophages

Thesis

van der Leij, RA;

Product: LIPID A monophosphoryl from Salmonella minnesota R595

LPS has been described in full detail as an inflammatory agent and can therefore be linked to the pr....

A Study Of Molecular Events In Lipopolysaccharide – Stimulated Murine B Lymphocytes (Two-Dimensional Gels, Lipid A, Receptors).

Thesis

Found, ALPSR;Gollahon, KA;

Product: LIPID A monophosphoryl from Salmonella minnesota R595

This study investigated two independent aspects of lipopolysaccharide (LPS) induced murine B cell mi....

MOLECULAR INSIGHTS ON PERTUSSIS TOXIN: STRUCTURE, FUNCTION, AND INHIBITION

Thesis

Sakari, M;

Product: Pertussis Toxin from B. pertussis (in Glycerol)

Vaccination against gammaherpesvirus attenuates viral enhanced disease in a murine model of multiple sclerosis

Thesis

Rosen, AR;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Multiple Sclerosis (MS) is a chronic, neurodegenerative autoimmune disease of the central nervous sy....

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Thesis

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Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

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Perinatal High Fat Diet Exposure Disrupts Development of Vagal Neurocircuits That Coordinate Gastric Motility

Thesis

Carson, K;

Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

Maternal obesity is a rapidly growing problem in the United States as only 2 out of 5 pregnant indiv....

Effects of Acute Alcohol Treatment on Macrophage Polarization

Thesis

Liu, L;

Product: ULTRA PURE LPS from Escherichia coli O111:B4

Influence of early microbial colonisation and the I?B transcription co-factor Bcl3 on intestinal immune homeostasis

Thesis

Kohler, AC;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

* Originaltitel: Influence of early microbial colonisation and the I?B transcription co-factor Bcl3 ....

Artificial melanin-like nanomaterials for biomedical application

Thesis

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Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Melanin is a comprehensive term referring to the dark pigment commonly present in biological entitie....

Major Histocompatibility Complex I and Its Role in Microglial Reactivity

Thesis

Kellogg, C;

Product: Pertussis Toxin from B. pertussis, Lyophilized (Salt-Free)

Parabrachial Neurons: Their Connections and Role in Maintaining Body Temperature, Wakefulness, and Appetite

Thesis

Grady, F;

Product: Anti-Cholera Toxin B Subunit (Goat)

Involvement of peptidergic Edinger-Westphal nucleus in the neurobiology of migraine and acute alcohol exposure

Thesis

Khalaf, AOAA;

Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

The main objective of this thesis was to examine the involvement of the centrally projecting Edinger....

Novel Mouse Models to Study the Role of T Cells in Cardiac Autoimmunity

Thesis

Sur, M;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Single-cell sequencing of the retina shows that LDHA regulates pathogenesis of autoimmune uveitis

Journal Of Autoimmunity

Peng, X;Li, H;Zhu, L;Zhao, S;Li, Z;Li, S;DongtingWu, ;Chen, J;Zheng, S;Su, W;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Autoimmune uveitis (AU) is a severe disorder causing poor vision and blindness. However, the cellula....

Metabolic fitness of IgA+ plasma cells in the gut requires DOCK8

Mucosal Immunology

Zhang, B;Chen, S;Yin, X;McBride, CD;Gertie, JA;Yurieva, M;Bielecka, AA;Hoffmann, B;Travis Hinson, J;Grassmann, J;Xu, L;Siniscalco, ER;Soldatenko, A;Hoyt, L;Joseph, J;Norton, EB;Uthaman, G;Palm, NW;Liu, E;Eisenbarth, SC;Williams, A;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

Dedicator of cytokinesis 8 (DOCK8) mutations lead to a primary immunodeficiency associated with recu....

TRAF6 signaling in T cells is crucial for the pathogenicity of experimental autoimmune encephalomyelitis

International Immunology

Kamiyama, N;Saechue, B;Sachi, N;Dewayani, A;Chalalai, T;Ozaka, S;Ariki, S;Soga, Y;Kagoshima, Y;Ekronarongchai, S;Hidano, S;Kobayashi, T;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Multiple sclerosis (MS) is an incurable chronic autoimmune disease affecting the central nervous sys....

FTY720 requires vitamin B12-TCN2-CD320 signaling in astrocytes to reduce disease in an animal model of multiple sclerosis

Cell Reports

Jonnalagadda, D;Kihara, Y;Groves, A;Ray, M;Saha, A;Ellington, C;Lee-Okada, HC;Furihata, T;Yokomizo, T;Quadros, EV;Rivera, R;Chun, J;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Vitamin B12 (B12) deficiency causes neurological manifestations resembling multiple sclerosis (MS); ....

Renal macrophages monitor and remove particles from urine to prevent tubule obstruction

Immunity

He, J;Cao, Y;Zhu, Q;Wang, X;Cheng, G;Wang, Q;He, R;Lu, H;Weng, Y;Mao, G;Bao, Y;Wang, J;Liu, X;Han, F;Shi, P;Shen, XZ;

Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae

When the filtrate of the glomerulus flows through the renal tubular system, various microscopic sedi....

Immunoswitch Nanomodulators Enable Active Targeting and Selective Proliferation of Regulatory T Cells for Multiple Sclerosis Therapy

ACS Nano

Wang, X;Liu, Z;Wang, D;Zhang, Y;Zhang, H;Xue, F;Wang, X;Tang, Z;Han, X;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Interleukin-2 (IL-2) used in multiple sclerosis (MS) therapy modulates the balance between regulator....

Tonabersat Significantly Reduces Disease Progression in an Experimental Mouse Model of Multiple Sclerosis

International Journal Of Molecular Sciences

Kwakowsky, A;Chawdhary, B;de Souza, A;Meyer, E;Kaye, AH;Green, CR;Stylli, SS;Danesh-Meyer, H;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Multiple sclerosis (MS) is a neurodegenerative disease marked by chronic neuroinflammation thought t....

Peripherally derived myeloid cells induce disease-dependent phenotypic changes in microglia

Frontiers In Cellular Neuroscience

Thougaard, E;Carney, B;Wlodarczyk, A;Brambilla, R;Lambertsen, KL;

Product: Pertussis Toxin from B. pertussis, Lyophilized (Salt-Free)

In central nervous system (CNS) injury and disease, peripherally derived myeloid cells infiltrate th....

Glycosylation-modified antigens as a tolerance-inducing vaccine platform prevent anaphylaxis in a pre-clinical model of food allergy

Cell Reports Medicine

Cao, S;Maulloo, CD;Raczy, MM;Sabados, M;Slezak, AJ;Nguyen, M;Solanki, A;Wallace, RP;Shim, HN;Wilson, DS;Hubbell, JA;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

The only FDA-approved oral immunotherapy for a food allergy provides protection against accidental e....

The long non-coding RNA HOTAIR contributes to joint-specific gene expression in rheumatoid arthritis

Nature Communications

Elhai, M;Micheroli, R;Houtman, M;Mirrahimi, M;Moser, L;Pauli, C;Bürki, K;Laimbacher, A;Kania, G;Klein, K;Schätzle, P;Bertoncelj, MF;Edalat, SG;Keusch, L;Khmelevskaya, A;Toitou, M;Geiss, C;Rauer, T;Sakkou, M;Kollias, G;Armaka, M;Distler, O;Ospelt, C;

Product: LPS from Escherichia coli J5 (Rc)

Although patients with rheumatoid arthritis (RA) typically exhibit symmetrical joint involvement, so....

A bead-based multiplex assay covering all coronaviruses pathogenic for humans for sensitive and specific surveillance of SARS-CoV-2 humoral immunity

Scientific Reports

Stern, D;Meyer, TC;Treindl, F;Mages, HW;Krüger, M;Skiba, M;Krüger, JP;Zobel, CM;Schreiner, M;Grossegesse, M;Rinner, T;Peine, C;Stoliaroff-Pépin, A;Harder, T;Hofmann, N;Michel, J;Nitsche, A;Stahlberg, S;Kneuer, A;Sandoni, A;Kubisch, U;Schlaud, M;Mankertz, A;Schwarz, T;Corman, VM;Müller, MA;Drosten, C;de la Rosa, K;Schaade, L;Dorner, MB;Dorner, BG;

Product: Pertussis Toxin from B. pertussis, Lyophilized (Salt-Free)

Serological assays measuring antibodies against SARS-CoV-2 are key to describe the epidemiology, pat....

Small-molecule targeting AMPA-mediated excitotoxicity has therapeutic effects in mouse models for multiple sclerosis

Science Advances

Zhai, D;Yan, S;Samsom, J;Wang, L;Su, P;Jiang, A;Zhang, H;Jia, Z;Wallach, I;Heifets, A;Zanato, C;Tseng, CC;Wong, AHC;Greig, IR;Liu, F;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

While most research and treatments for multiple sclerosis (MS) focus on autoimmune reactions causing....

Horizontal gene transfer shapes pathogenic bacteria in multiple sclerosis

Research Square

Yamamura, T;Takewaki, D;Kiguchi, Y;Masuoka, H;Manu, M;Raveney, B;Narushima, S;Kurokawa, R;Ogata, Y;Kimura, Y;Sato, N;Ozawa, Y;Yagishita, S;Araki, T;Miyake, S;Sato, W;Suda, W;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Multiple sclerosis (MS) is an autoimmune demyelinating disease influenced by environmental factors. ....

Chronic Adaptations in the Dorsal Horn following a cervical spinal cord injury in primates

The Journal Of Neuroscience

Fisher, K;Garner, J;Darian-Smith, C;

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Spinal cord injury (SCI) is devastating, with limited treatment options and variable outcomes. Most ....

Synaptic circuits involving gastrin-releasing peptide receptor-expressing neurons in the dorsal horn of the mouse spinal cord

Frontiers In Molecular Neuroscience

Quillet, R;Gutierrez-Mecinas, M;Polgár, E;Dickie, AC;Boyle, KA;Watanabe, M;Todd, AJ;

Product: Anti-Cholera Toxin B Subunit (Goat)

The superficial dorsal horn (SDH) of the spinal cord contains a diverse array of neurons. The vast m....

Acupuncture ameliorates experimental autoimmune encephalomyelitis via inhibiting the antigen presentation function of astrocytes

Research Square

Wang, J;Lei, Y;Zhu, F;Yu, J;Huo, X;Yang, C;Zhao, P;Huang, Y;Hao, M;Liu, Y;Liu, X;Li, H;Sun, B;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Multiple sclerosis (MS) is a chronic inflammatory disease occurring in the central nervous system (C....

The circadian clock time tunes axonal regeneration

Cell Metabolism

De Virgiliis, F;Mueller, F;Palmisano, I;Chadwick, JS;Luengo-Gutierrez, L;Giarrizzo, A;Yan, Y;Danzi, MC;Picon-Muñoz, C;Zhou, L;Kong, G;Serger, E;Hutson, TH;Maldonado-Lasuncion, I;Song, Y;Scheiermann, C;Brancaccio, M;Di Giovanni, S;

Product: Anti-Cholera Toxin B Subunit (Goat)

Nerve injuries cause permanent neurological disability due to limited axonal regeneration. Injury-de....

Transient Receptor Potential Vanilloid 4-Dependent Microglial Function in Myelin Injury and Repair

International Journal Of Molecular Sciences

Holloman, JP;Dimas, SH;Archambault, AS;Filipello, F;Du, L;Feng, J;Zhao, Y;Bollman, B;Piccio, L;Steelman, AJ;Hu, H;Wu, GF;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Microglia are found pathologically at all stages of multiple sclerosis (MS) lesion development and a....

A brainstem circuit for phonation and volume control in mice

Nature Neuroscience

Veerakumar, A;Head, JP;Krasnow, MA;

Product: Anti-Cholera Toxin B Subunit (Goat)

Mammalian vocalizations are critical for communication and are produced through the process of phona....

Altered response to Toll-like receptor 4 activation in fibromyalgia: A low-dose, human experimental endotoxemia pilot study

Brain, Behavior, & Immunity - Health

Jones, C;Parkitny, L;Strath, L;Wagener, BM;Barker, A;Younger, J;

Product: LIST™ HPT™ from Escherichia coli O113

In this pilot study, a human intravenous injection of low-dose endotoxin (lipopolysaccharide, LPS) m....

Huangqi-Guizhi-Wuwu Decoction regulates differentiation of CD4+ T cell and prevents against experimental autoimmune encephalomyelitis progression in mice

Phytomedicine

Xu, N;Han, X;Zhang, X;Wang, J;Yuan, J;Wang, M;Wu, H;Huang, F;Shi, H;Yang, L;Wu, X;

Product: Pertussis Toxin from B. pertussis, Lyophilized (Salt-Free)

Background Multiple sclerosis (MS) is a demyelination disorder caused by an overactive immune respon....

SPINAL V1 INHIBITORY INTERNEURON CLADES DIFFER IN BIRTHDATE, PROJECTIONS TO MOTONEURONS AND HETEROGENEITY

Biorxiv : The Preprint Server For Biology

Worthy, AE;Anderson, JT;Lane, AR;Gomez-Perez, L;Wang, AA;Griffith, RW;Rivard, AF;Bikoff, JB;Alvarez, FJ;

Product: Anti-Cholera Toxin B Subunit (Goat)

Spinal cord interneurons play a crucial role in shaping motor output, but their precise identity and....

Local regulation of T-cell immunity in the intestinal mucosa

Thesis

María Josefina Peña Mosca

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Summary After priming in Peyer’s patches (PPs) and mesenteric lymph nodes (mLN) Tcells infiltr....

OCA-B promotes autoimmune demyelination through control of stem-like CD4 + T cells

Biorxiv : The Preprint Server For Biology

Hughes, EP;Syage, A;Mehrabad, EM;Lane, TE;Spike, BT;Tantin, D;

Product: Pertussis Toxin from B. pertussis, Lyophilized (Salt-Free)

Stem-like T cell populations can selectively promote autoimmunity, but the activities that sustain t....

CTRP4/Interleukin-6 receptor signaling ameliorates autoimmune encephalomyelitis by suppressing Th17 cell differentiation

The Journal Of Clinical Investigation

Cao, L;Deng, J;Chen, W;He, M;Zhao, N;Huang, H;Ling, L;Li, Q;Zhu, X;Wang, L;

Product: Pertussis Toxin from B. pertussis (in Glycerol)

C1q/TNF related protein 4 (CTRP4) is generally thought to be released extracellularly and plays a cr....

Region-specific response of central microglial cells to sciatic nerve demyelination through sensory and motor pathways

Histology And Histopathology

Wu, S;Su, Y;Wang, Y;Wang, J;Xu, D;Liu, Y;Yang, K;Gao, J;Cui, J;Bai, W;

Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

Peripheral nerve injury can cause changes in microglial cells on the spinal dorsal and ventral horns....

Adipose cDC1s contribute to obesity-associated inflammation through STING-dependent IL-12 production

Nature Metabolism

Hildreth, AD;Padilla, ET;Gupta, M;Wong, YY;Sun, R;Legala, AR;O'Sullivan, TE;

Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae

Obesity is associated with chronic low-grade white adipose tissue (WAT) inflammation that can contri....

Exosomal miR-23a-3p derived from human umbilical cord mesenchymal stem cells promotes remyelination in central nervous system demyelinating diseases by targeting Tbr1/Wnt pathway

The Journal Of Biological Chemistry

Qin, D;Wang, C;Li, D;Guo, S;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Oligodendrocyte precursor cells (OPCs) are present in the adult central nervous system (CNS), and th....

Oral vancomycin treatment suppresses gut trypsin activity and preserves intestinal barrier function during EAE

Iscience

Bianchimano, P;Iwanowski, K;Smith, EM;Cantor, A;Leone, P;Bongers, G;Gonzalez, CG;Hongsup, Y;Elias, J;Weiner, HL;Clemente, JC;Tankou, SK;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Studies have reported increased intestinal permeability in multiple sclerosis (MS) patients and its ....

Ly6C-high monocytes alleviate brain injury in experimental subarachnoid hemorrhage in mice

Journal Of Neuroinflammation

Chen, H;Xu, C;Zeng, H;Zhang, Z;Wang, N;Guo, Y;Zheng, Y;Xia, S;Zhou, H;Yu, X;Fu, X;Tang, T;Wu, X;Chen, Z;Peng, Y;Cai, J;Li, J;Yan, F;Gu, C;Chen, G;Chen, J;

Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae

Background Subarachnoid hemorrhage (SAH) is an uncommon type of potentially fatal stroke. The pathop....

A novel mouse model of cerebral adrenoleukodystrophy highlights NLRP3 activity in lesion pathogenesis

Biorxiv

Hashemi, E;Narain Srivastava, I;Aguirre, A;Tilahan Yoseph, E;Kaushal, E;Awani, A;Kyu Ryu, J;Akassoglou, K;Talebian, S;Chu, P;Pisani, L;Musolino, P;Steinman, L;Doyle, K;Robinson, WH;Sharpe, O;Cayrol, R;Orchard, P;Lund, T;Vogel, H;Lenail, M;Han, MH;Bonkowsky, JL;Van Haren, KP;

Product: Pertussis Toxin from B. pertussis, Lyophilized (Salt-Free)

Objective: We sought to create and characterize a mouse model of the inflammatory, cerebral demyelin....

TRAF6 and TRAF2/3 Binding Motifs in CD40 Differentially Regulate B Cell Function in T-Dependent Antibody Responses and Dendritic Cell Function in Experimental Autoimmune Encephalomyelitis

Journal Of Immunology

Lu, Y;Chiang, J;Zhang, R;Roche, PA;Hodes, RJ;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Expression of the costimulatory molecule CD40 on both B cells and dendritic cells (DCs) is required ....

Critical role of CD206+ macrophages in organizing anti-tumor immunity

Biorxiv

Ray, A;Hu, KH;Kersten, K;Kuhn, NF;Samad, B;Combes, AJ;Krummel, MF;

Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae

Tumor-associated macrophages (TAMs) are frequently and simplistically categorized as immunosuppressi....

Targeting PGLYRP1 promotes antitumor immunity while inhibiting autoimmune neuroinflammation

Nature Immunology

Schnell, A;Huang, L;Regan, BML;Singh, V;Vonficht, D;Bollhagen, A;Wang, M;Hou, Y;Bod, L;Sobel, RA;Chihara, N;Madi, A;Anderson, AC;Regev, A;Kuchroo, VK;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Co-inhibitory and checkpoint molecules suppress T cell function in the tumor microenvironment, there....

Rapid activation of IL-2 receptor signaling by CD301b+DC-derived IL-2 dictates the outcome of helper T cell differentiation

Biorxiv

Tatsumi, N;El-Fenej, J;Davila-Pagan, A;Kumamoto, Y;

Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae

Effector T helper (Th) cell differentiation is fundamental to functional adaptive immunity. Differen....

Cutting Edge: Serpine1 Negatively Regulates Th1 Cell Responses in Experimental Autoimmune Encephalomyelitis

Journal Of Immunology

Akbar, I;Tang, R;Baillargeon, J;Roy, AP;Doss, PMIA;Zhu, C;Kuchroo, VK;Rangachari, M;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Th1 cells are critical in experimental autoimmune encephalomyelitis (EAE). Serine protease inhibitor....

Characterizing a Silver Nanoparticle-Based Electrochemical Biosensor for Shiga Toxin Detection

ACS Omega

Patel, D;Hansen, M;Lambert, C;Hegde, S;Jayamohan, H;Gale, B;Sant, H;

Product: Shiga Toxin 1 from Escherichia coli

Shiga toxins (1, 2) regularly cause outbreaks and food recalls and pose a significant health risk to....

Longitudinal in vivo evaluation of retinal ganglion cell complex layer and dendrites in mice with experimental autoimmune encephalomyelitis

Experimental Eye Research

Qian, Z;Zheng, K;Xu, Y;Chen, S;Chen, S;Liang, J;Cao, Y;Ng, TK;Qiu, K;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Experimental autoimmune encephalomyelitis (EAE), induced by the immunization of myelin oligodendrocy....

Discovery of Clinical Candidate NT-0796, a Brain-Penetrant and Highly Potent NLRP3 Inflammasome Inhibitor for Neuroinflammatory Disorders

Journal Of Medicinal Chemistry

Harrison, D;Billinton, A;Bock, MG;Doedens, JR;Gabel, CA;Holloway, MK;Porter, RA;Reader, V;Scanlon, J;Schooley, K;Watt, AP;

Product: Anthrax Protective Antigen (PA), Recombinant from B. anthracis

The NLRP3 inflammasome is a component of the innate immune system involved in the production of proi....

Integrin α3 promotes TH17 cell polarization and extravasation during autoimmune neuroinflammation

Science Immunology

Park, E;Barclay, WE;Barrera, A;Liao, TC;Salzler, HR;Reddy, TE;Shinohara, ML;Ciofani, M;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) caused by CNS-i....

Global lactylome reveals lactylation-dependent mechanisms underlying TH17 differentiation in experimental autoimmune uveitis

Science Advances

Fan, W;Wang, X;Zeng, S;Li, N;Wang, G;Li, R;He, S;Li, W;Huang, J;Li, X;Liu, J;Hou, S;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Dysregulation of CD4+ T cell differentiation is linked to autoimmune diseases. Metabolic reprogrammi....

Anthrax lethal toxin and tumor necrosis factor-α synergize on intestinal epithelia to induce mouse death

Protein & Cell

Gao, X;Teng, T;Liu, Y;Ai, T;Zhao, R;Fu, Y;Zhang, P;Han, J;Zhang, Y;

Product: Anthrax Protective Antigen (PA), Recombinant from B. anthracis

Bacillus anthracis (B. anthracis) lethal toxin (LT) is a determinant of lethal anthrax. Its function....

Autotaxin in encephalitogenic CD4 T cells as a therapeutic target for multiple sclerosis

European Journal Of Immunology

Petersen-Cherubini, CL;Murphy, SP;Xin, M;Liu, Y;Deffenbaugh, JL;Jahan, I;Rau, CN;Yang, Y;Lovett-Racke, AE;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Multiple sclerosis (MS) is an immune-mediated inflammatory disease of the CNS. A defining characteri....

Evaluation of an in vitro experimental platform of human polarized intestinal epithelial monolayers for the hazard assessment of insecticidal proteins

Food And Chemical Toxicology : An International Journal Published For The British Industrial Biological Research Association

Zimmermann, CS;Snow, RF;Wilson-Mifsud, B;LeRoy, K;Boeckman, C;Huang, E;Mathesius, CA;Roper, JM;Hurley, BP;

Product: Toxin B from Clostridium difficile

Previous work demonstrated the utility of using human-derived intestinal epithelial cell (IEC) lines....

Shiga toxin targets the podocyte causing hemolytic uremic syndrome through endothelial complement activation

Med

Bowen, EE;Hurcombe, JA;Barrington, F;Keir, LS;Farmer, LK;Wherlock, MD;Ortiz-Sandoval, CG;Bruno, V;Bohorquez-Hernandez, A;Diatlov, D;Rostam-Shirazi, N;Wells, S;Stewart, M;Teboul, L;Lay, AC;Butler, MJ;Pope, RJP;Larkai, EMS;Morgan, BP;Moppett, J;Satchell, SC;Welsh, GI;Walker, PD;Licht, C;Saleem, MA;Coward, RJM;

Product: Shiga Toxin 2 from Escherichia coli

Shiga toxin (Stx)-producing Escherichia coli hemolytic uremic syndrome (STEC-HUS) is the leading cau....

Tafluprost promotes axon regeneration after optic nerve crush via Zn2+-mTOR pathway

Neuropharmacology

Wu, S;Liu, C;Tang, J;Wu, C;Zhang, Q;Liu, Z;Han, J;Xue, J;Lin, J;Chen, Y;Yang, J;Zhuo, Y;Li, Y;

Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

Purpose To investigate whether Tafluprost could promote optic nerve regeneration in mice after optic....

Remyelination protects neurons from DLK-mediated neurodegeneration

Biorxiv : The Preprint Server For Biology

Duncan, GJ;Ingram, SD;Emberley, K;Hill, J;Cordano, C;Abdelhak, A;McCane, M;Jabassini, N;Ananth, K;Ferrara, SJ;Stedelin, B;Sivyer, B;Aicher, SA;Scanlan, T;Watkins, TA;Mishra, A;Nelson, J;Green, AJ;Emery, B;

Product: Pertussis Toxin from B. pertussis, Lyophilized (Salt-Free)

Chronic demyelination is theorized to contribute to neurodegeneration and drive progressive disabili....

Teriflunomide Promotes Blood-Brain Barrier Integrity by Upregulating Claudin-1 via the Wnt/?-catenin Signaling Pathway in Multiple Sclerosis

Molecular Neurobiology

Zhao, Y;Chen, C;Xiao, X;Fang, L;Cheng, X;Chang, Y;Peng, F;Wang, J;Shen, S;Wu, S;Huang, Y;Cai, W;Zhou, L;Qiu, W;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

The blood-brain barrier (BBB) and tight junction (TJ) proteins maintain the homeostasis of the centr....

Muscimol inhibits plasma membrane rupture and ninjurin-1 oligomerization during pyroptosis

Communications Biology

den Hartigh, AB;Loomis, WP;Anderson, MJ;Frølund, B;Fink, SL;

Product: Anthrax Protective Antigen (PA), Recombinant from B. anthracis

Pyroptosis is a cell death process that causes inflammation and contributes to numerous diseases. Py....

Role of Autoreactive Tc17 Cells in the Pathogenesis of Experimental Autoimmune Encephalomyelitis (EAE)

Research Square

Peng, Y;Zhang, X;Tang, Y;He, S;Rao, G;Chen, Q;Xue, Y;Jin, H;Liu, S;Zhou, Z;Xiang, Y;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Background The pathogenesis of multiple sclerosis (MS) and its animal model, experimental autoimmune....

Retinal transcriptome profiling identifies novel candidate genes associated with visual impairment in a mouse model of multiple sclerosis

Animal Cells And Systems

Hong, S;Weerasinghe-Mudiyanselage, PDE;Kang, S;Moon, C;Shin, T;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Visual impairment is occasionally observed in multiple sclerosis (MS) and its animal model, experime....

Ros-Dependent Palmitoylation Activates Pore Formation by Cleaved and Intact Gsdmd

Cell

Du, G;Healy, L;David, L;Walker, C;El-Baba, T;Lutomski, C;Goh, B;Pi, X;Fontana, P;Dong, Y;Ma, X;Miao, R;Devant, P;Puthenveetil, R;Banerjee, A;Kagan, J;Oh, S;Robinson, C;Lieberman, J;Wu, H;

Product: Anthrax Protective Antigen (PA), Recombinant from B. anthracis

Here we report that S-palmitoylation at Cys191 of GSDMD enables pore formation by both cleaved GSDMD....

Interferon restores replication fork stability and cell viability in BRCA-defective cells via ISG15

Nature Communications

Moro, RN;Biswas, U;Kharat, SS;Duzanic, FD;Das, P;Stavrou, M;Raso, MC;Freire, R;Chaudhuri, AR;Sharan, SK;Penengo, L;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

DNA replication and repair defects or genotoxic treatments trigger interferon (IFN)-mediated inflamm....

IL-12 sensing in neurons induces neuroprotective CNS tissue adaptation and attenuates neuroinflammation in mice

Nature Neuroscience

Andreadou, M;Ingelfinger, F;De Feo, D;Cramer, TLM;Tuzlak, S;Friebel, E;Schreiner, B;Eede, P;Schneeberger, S;Geesdorf, M;Ridder, F;Welsh, CA;Power, L;Kirschenbaum, D;Tyagarajan, SK;Greter, M;Heppner, FL;Mundt, S;Becher, B;

Product: Pertussis Toxin from B. pertussis (in Glycerol)

Interleukin-12 (IL-12) is a potent driver of type 1 immunity. Paradoxically, in autoimmune condition....

Identification of the regulatory circuit governing corneal epithelial fate determination and disease

Plos Biology

Smits, JGA;Cunha, DL;Amini, M;Bertolin, M;Laberthonnière, C;Qu, J;Owen, N;Latta, L;Seitz, B;Roux, LN;Stachon, T;Ferrari, S;Moosajee, M;Aberdam, D;Szentmary, N;van Heeringen, SJ;Zhou, H;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

The transparent corneal epithelium in the eye is maintained through the homeostasis regulated by lim....

Transgenic Mice Expressing Functional TCRs Specific to Cardiac Myhc-α 334–352 on Both CD4 and CD8 T Cells Are Resistant to the Development of Myocarditis on C57BL/6 Genetic Background

Cells

Sur, M;Rasquinha, M;Arumugam, R;Massilamany, C;Gangaplara, A;Mone, K;Lasrado, N;Yalaka, B;Doiphode, A;Gurumurthy, C;Steffen, D;Reddy, J;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Myocarditis is a predominant cause of congestive heart failure and sudden death in children and youn....

Presynaptic Release-Regulating Sphingosine 1-Phosphate 1/3 Receptors in Cortical Glutamatergic Terminals: Adaptations in EAE Mice and Impact of Therapeutic FTY720

Cells

Roggeri, A;Olivero, G;Usai, C;Vanmierlo, T;Pittaluga, A;

Product: Pertussis Toxin from B. pertussis, Lyophilized (Salt-Free)

This study provides evidence of the existence of presynaptic inhibitory sphingosine-1-phosphate rece....

TIM-4 Identifies Effector B Cells Expressing An IL-23-Driven Proinflammatory Cytokine Module That Promotes Immune Responses

Biorxiv : The Preprint Server For Biology

Ding, Q;Wu, Y;Triglia, ET;Gommerman, JL;Subramanian, A;Kuchroo, VK;Rothstein, DM;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

B cells can express pro-inflammatory cytokines that promote a wide variety of immune responses. Here....

Commensal bacteria signal through TLR5 and AhR to improve barrier integrity and prevent allergic responses to food

Cell Reports

Kemter, AM;Patry, RT;Arnold, J;Hesser, LA;Campbell, E;Ionescu, E;Mimee, M;Wang, S;Nagler, CR;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

The increasing prevalence of food allergies has been linked to reduced commensal microbial diversity....

A Mouse Model of Shrimp Allergy with Cross-Reactivity to Crab and Lobster

Methods In Molecular Biology

Smeekens, JM;Kesselring, JR;Bagley, K;Kulis, MD;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

Food allergies are a growing public health problem with recent estimates of 10% of the US population....

Metabolic modulation of mitochondrial mass during CD4+ Tcell activation

Cell Chemical Biology

Kurmi, K;Liang, D;van de Ven, R;Georgiev, P;Gassaway, BM;Han, S;Notarangelo, G;Harris, IS;Yao, CH;Park, JS;Hu, SH;Peng, J;Drijvers, JM;Boswell, S;Sokolov, A;Dougan, SK;Sorger, PK;Gygi, SP;Sharpe, AH;Haigis, MC;

Product: Pertussis Toxin from B. pertussis, Lyophilized (Salt-Free)

Mitochondrial biogenesis initiates within hours of T cell receptor (TCR) engagement and is critical ....

Naringenin confers protection against experimental autoimmune encephalomyelitis through modulating the gut-brain axis: A multi-omics analysis

The Journal Of Nutritional Biochemistry

Liu, Z;Sun, M;Jin, C;Sun, X;Feng, F;Niu, X;Wang, B;Zhang, Y;Wang, J;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Multiple sclerosis (MS) is a disease of the central nervous system that involves the immune system a....

A novel monoclonal antibody against 6-sulfo sialyl Lewis x glycans attenuates murine allergic rhinitis by suppressing Th2 immune responses

Scientific Reports

Liu, W;Xiong, W;Liu, W;Hirakawa, J;Kawashima, H;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

Lymphocyte homing is mediated by the interaction between L-selectin on lymphocytes and its glycoprot....

Th17/Treg balance is restored during the suppression of experimental autoimmune encephalomyelitis treated by Astragalus polysaccharides via the microbiota-gut-brain axis

Research Square

Ma, J;Lu, Q;Zhao, Y;Liu, X;Ding, G;Wang, Y;Wang, X;Chen, Y;Zhang, T;Cheng, X;

Product: Pertussis Toxin from B. pertussis, Lyophilized (Salt-Free)

The Th17/Treg imbalance is an important cause of immune cell infiltration into the central nervous s....

VE-cadherin in arachnoid and pia mater cells serves as a suitable landmark for in vivo imaging of CNS immune surveillance and inflammation

Nature Communications

Mapunda, JA;Pareja, J;Vladymyrov, M;Bouillet, E;Hélie, P;Pleska?, P;Barcos, S;Andrae, J;Vestweber, D;McDonald, DM;Betsholtz, C;Deutsch, U;Proulx, ST;Engelhardt, B;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Meninges cover the surface of the brain and spinal cord and contribute to protection and immune surv....

Volitional inspiration is mediated by two independent output channels in the primary motor cortex

The Journal Of Comparative Neurology

Helou, LB;Dum, RP;

Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

The diaphragm is a multifunctional muscle that mediates both autonomic and volitional inspiration. I....

Chimeric CNS-targeting-peptide engineered exosomes for experimental autoimmune encephalomyelitis therapy

International Immunopharmacology

Wang, YK;Zhao, YP;Ye, MZ;Wang, L;Lan, TS;Wang, Y;Qi, ZQ;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS) that causes d....

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Bacterial Toxin Terminology

July 23, 2018

By: douano@listlabs.com

By: Mary N. Wessling, Ph.D. ELS In this blog we will unravel the terminology describing bacterial toxins. In general, there are at least three ways that bacterial toxins are described in the literature: by their biological designation—the genus and/or species from which they come by the origin of the toxin, either as innate to the […]

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