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#100B (1 mg)

Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

Info

APOPTOSIS PRODUCT BULLETIN
CHOLERA TOXIN PRODUCT BULLETIN
SIGNAL TRANSDUCTION PRODUCT BULLETIN
COA

Current
Certificate of Testing for Lot# 10071A2
Archived
Certificate of Testing for Lot# 10071A1
Certificate of Analysis for Lot # 10070A1
Certificate of Analysis for Lot # 10069A1
Certificate of Analysis for Lot # 10067A1
Certificate of Analysis for Lot # 10068A1
Certificate of Analysis for Lot # 10060A2
Certificate of Analysis for Lot # 10063A1
SDS

100-sdsv4-128-1-8-pdf-8
Poster

Current
HPLC Method to Assay the ADP-Ribosyltransferase Activity of Cholera Toxin

$375.00

#104 (0.5 mg)

Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

Info

FITC AND BIOTIN CONJUGATES OF CHOLERA TOXIN B SUBUNIT
CHOLERA TOXIN PRODUCT BULLETIN
COA

Current
Certificate of Testing for Lot # 10434A1
Archived
Certificate of Analysis for Lot # 10433A1
Certificate of Analysis for Lot # 10430A1
Certificate of Analysis for Lot # 10431A1
Certificate of Analysis for Lot # 10432A1
Certificate of Analysis for Lot # 10431B1
N-HAZ

non-hazardous-statement-conjugates-129-1-pdf
Poster

Current
HPLC Method to Assay the ADP-Ribosyltransferase Activity of Cholera Toxin

$600.00

#106 (0.2 mg)

Cholera Toxin B Subunit (CTB) from Vibrio cholerae FITC, Conjugate

Info

CHOLERA TOXIN PRODUCT BULLETIN
FITC AND BIOTIN CONJUGATES OF CHOLERA TOXIN B SUBUNIT
COA

Current
Certificate of Analysis for Lot # 10616A v02
Archived
Certificate of Analysis for Lot # 10616A
N-HAZ

non-hazardous-statement-conjugates-12-1-pdf

$720.00

#112 (0.2 mg)

Cholera Toxin B Subunit Biotin Conjugate

Info

CHOLERA TOXIN AND RELATED PRODUCTS
FITC AND BIOTIN CONJUGATES OF CHOLERA TOXIN B SUBUNIT
COA

Current
Certificate of Analysis for Lot # 11212A1
Archived
Certificate of Analysis for Lot # 11211A1
N-HAZ

non-hazardous-statement-conjugates-226-1-pdf

$695.00

#133L (Liquid)

Botulinum Neurotoxin Type A Toxoid from Clostridium botulinum

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 1333A7
Archived
Certificate of Analysis for Lot # 1333A1
Certificate of Analysis for Lot # 1333A3
Certificate of Analysis for Lot # 1333A4
N-HAZ

non-hazardous-statement-toxoids-28-1-pdf

#149A (0.25 mg)

Diphtheria Toxin CRM197, Mutant

Info

DIPHTHERIA TOXIN, TOXOID, CRM MUTANT PRODUCT BULLETIN
Diphtheria Toxin and Engineered Receptor
Protein Carriers for Vaccines
COA

Current
Certificate of Analysis for Lot # 14937A1
Archived
Certificate of Analysis for Lot # 14936A1
Certificate of Analysis for Lot # 14934A1
Certificate of Analysis for Lot # 14935A1
N-HAZ

non-hazardous-statement-v2

$525.00

#150 (1 mg)

Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae

This product is Out of stock.

Info

APOPTOSIS PRODUCT BULLETIN
DIPHTHERIA TOXIN, TOXOID, CRM MUTANT PRODUCT BULLETIN
Diphtheria Toxin and Engineered Receptor
Protein Carriers for Vaccines
COA

Current
Certificate of Analysis for Lot # 15047A1
Archived
Certificate of Analysis for Lot # 15046A1
Certificate of Analysis for Lot #15045A1
Certificate of Analysis for Lot # 15042B1
Certificate of Analysis for Lot # 15043A1
SDS

150-sdsv3-35-1-pdf

#151 (0.5 mg)

Diphtheria Toxoid, from Corynebacterium diphtheriae

This product is Out of stock.

Info

DIPHTHERIA TOXIN, TOXOID, CRM MUTANT PRODUCT BULLETIN
Diphtheria Toxin and Engineered Receptor
COA

Current
Certificate of Analysis for Lot # 1519A1 v02
Archived
Certificate of Analysis for Lot # 1518A1
N-HAZ

non-hazardous-statement-toxoids-36-1-pdf

#152C (100 ug)

Toxin A from Clostridium difficile

Info

APOPTOSIS PRODUCT BULLETIN
C. DIFFICILE TOXINS PRODUCT BULLETIN
SIGNAL TRANSDUCTION PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Analysis for Lot # 15219A3 v02
Archived
Certificate of Analysis for Lot # 15219A2
Certificate of Analysis for Lot # 15215A1C
Certificate of Analysis for Lot # 15215A5
SDS

152-sdsv3-209-1-pdf

$565.00

#155L (liquid)

Toxin B from Clostridium difficile

Info

APOPTOSIS PRODUCT BULLETIN
C. DIFFICILE TOXINS PRODUCT BULLETIN
SIGNAL TRANSDUCTION PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Testing for Lot #15522A3 v01
Archived
Certificate of Testing for Lot #15522A2 v01
Certificate of Analysis for Lot # 15521G1B
Certificate of Analysis for Lot # 15521G1A
Certificate of Analysis for Lot # 15521A1
Certificate of Analysis for Lot # 15522A1
Certificate of Analysis for Lot # 15518A1A
Certificate of Analysis for Lot # 15520A3A
Certificate of Analysis for Lot # 15520A4A
Certificate of Analysis for Lot # 15520A3B
Certificate of Analysis for Lot # 15521A2
SDS

155-sdsv5-41-1-pdf

$915.00

#156 (50 ug)

Pasteurella multocida Toxin

Info

APOPTOSIS PRODUCT BULLETIN
PASTEURELLA MULTOCIDA TOXIN PRODUCT BULLETIN
SIGNAL TRANSDUCTION PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 1566C1
Archived
Certificate of Analysis for Lot # 1566A1
SDS

156-sdsv3-44-1-pdf

$555.00

#157A (20 ug)

Binary Toxin from Clostridium difficile, A Subunit

This product is discontinued.

Info

C. DIFFICILE TOXINS PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Analysis for Lot # 1573A1
N-HAZ

non-hazardous-statement-other-toxins-201-1-pdf

#159A (0.1 mg)

Glutamate Dehydrogenase (GDH) from Clostridium difficile

This product is discontinued.

Info

C. DIFFICILE TOXINS PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Analysis for Lot # 1591A2
N-HAZ

non-hazardous-statement-other-toxins-222-1-pdf

#161 (10 ug)

Shiga Toxin 1 from Escherichia coli

Info

SHIGA TOXINS Product information
COA

Current
Certificate of Analysis for Lot # 1611A1
SDS

161-sdsv3-174-1-pdf

$835.00

#162L (Liquid)

Shiga Toxin 2 from Escherichia coli

COA

Current
Certificate of Analysis for Lot # 1623A1 v05
Archived
Certificate of Analysis for Lot # 1621A1
Certificate of Analysis for Lot # 1622A1
SDS

162-162l-and-164-sdsv5-176-1-pdf

$955.00

#169L (Liquid)

Anthrax Lethal Factor (LF-A), Recombinant from B. anthracis Native Sequence

Info

MAPKKIDE PLUS PRODUCT BULLETIN
ANTHRAX TOXIN PRODUCT BULLETIN
LETHAL FACTOR, NATIVE SEQUENCE, DESCRIPTION
COA

Current
Certificate of Analysis for Lot # 1694A1
Certificate of Analysis for Lot # 1692A1B
N-HAZ

non-hazardous-statement-anthrax-toxins-03-15-18-172-1-pdf

$490.00

#170L (Liquid)

Filamentous Hemagglutinin (FHA) from Bordetella pertussis

Info

BORDETELLA VIRULENCE FACTORS PRODUCT INFORMATION
PERTUSSIS TOXIN FROM BORDETELLA PERTUSSIS PRODUCT INFORMATION
SIGNAL TRANSDUCTION PRODUCT BULLETIN
COA

Current
Certificate of Testing for Lot#17056A1
N-HAZ

non-hazardous-statement-other-toxins-158-1-pdf

$450.00

#171E (0.5 mg)

Anthrax Protective Antigen (PA), Recombinant from B. anthracis

Product # 171 is the entire 83 kDa native protein; This product contains the entire anthrax protective antigen 83 kDa native protein.

Info

MAPKKIDE PLUS PRODUCT BULLETIN
ANTHRAX TOXIN PRODUCT BULLETIN
MAPKKIDE PRODUCT BULLETIN
COA

Current
Certificate of Testing for Lot # 17121A2
Archived
Certificate of Analysis for Lot # 17121A1
Certificate of Analysis for Lot # 17120A1
Certificate of Analysis for Lot # 17119A1B
N-HAZ

non-hazardous-statement-anthrax-toxins-210-1-pdf

$750.00

#172B (1 mg), #172L (1 mg),

Anthrax Lethal Factor (LF), Recombinant from B. anthracis

Info

MAPKKIDE PLUS PRODUCT BULLETIN
ANTHRAX TOXIN PRODUCT BULLETIN
MAPKKIDE PRODUCT BULLETIN
COA

Current
172B (1 mg)
Certificate of Analysis for Lot # 1722B15A1 v03
172L (1 mg)
Certificate of Analysis for Lot # 1722B15A2 v03
Archived
172B (1 mg)
Certificate of Analysis for Lot # 1722B10B
172B (1 mg)
Certificate of Analysis for Lot # 1722B11B
172B (1 mg)
Certificate of Analysis for Lot # 17210A1B
172L (1 mg)
Certificate of Analysis for Lot # 1722B15A1
N-HAZ

non-hazardous-statement-anthrax-toxins-53-1-2-pdf-2
Poster

Current
FRET Peptide Substrates for the Botulinum Toxins Type A, B, and E and for Anthrax Lethal Factor
Physical Characteristics of rLF and rPA: Effects on Enzymatic Activity and Binding
Internally Quenched Fluorogenic Substrates for Anthrax Lethal Factor.
Sensitive Detection of Anthrax Lethal Factor in Plasma Using a Specific Biotinylated Fluorogenic Substrate
A Novel Substrate for Specific Detection of Anthrax Infection

$775.00 – $1,025.00

#173B (0.5 mg)

Anthrax Edema Factor (EF), Recombinant, Mutant S447N from B. anthracis

Info

ANTHRAX TOXIN PRODUCT BULLETIN
ADENYLATE CYCLASE TOXIN PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 1732A1
N-HAZ

non-hazardous-statement-anthrax-toxins-56-1-2-pdf-2

$980.00

#174 (0.5 mg)

Anthrax Protective Antigen, Activated (PA 63) from B. anthracis

Product # 174 is PA63, which has been created by enzymatic digestion and purified;

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 17410A1 Rev. 2021
Archived
Certificate of Analysis for Lot # 17410A1
Certificate of Analysis for Lot # 1749A1
Certificate of Analysis for Lot # 17410A1
N-HAZ

non-hazardous-statement-anthrax-toxins-57-1-pdf

$625.00

#175 (50 ug)

Anthrax PA 63 - FITC Conjugate

Product # 175 is purified PA63 conjugated to FITC for visualization.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 1752A1v02
Archived
Certificate of Analysis for Lot # 1751A
N-HAZ

non-hazardous-statement-anthrax-toxins-59-1-pdf

$475.00

#176B (1 mg),

Anthrax Lethal Factor (LF), Recombinant, Mutant E687C from B. anthracis

Info

ANTHRAX TOXIN PROTECTIVE ANTIGEN, LETHAL FACTOR, EDEMA FACTOR From Bacillus anthracis
COA

Current
Certificate of Analysis for Lot # 1761AA Size A
Certificate of Analysis for Lot # 1761AA
N-HAZ

non-hazardous-statement-anthrax-toxins-60-1-pdf

$945.00

#177A (50 ug), #177B (.25mg),

Anthrax Protective Antigen Fragment (PA 20) from B. anthracis

Product # 177 is PA20, the approximately 20 kDA fragment cleaved from PA; and

Info
COA

Current
Certificate of Analysis for Lot # 1771A1 v02 Size A
Certificate of Analysis for Lot # 1771A1 v02 Size B
Archived
Certificate of Analysis for Lot # 1771A1 Size A
N-HAZ

non-hazardous-statement-anthrax-toxins-62-1-pdf

$355.00 – $675.00

#178A (0.1 mg)

Anthrax Edema Factor (EF), Recombinant from B. anthracis

Info
COA

Current
Certificate of Analysis for Lot # 1785A1A v02
Archived
Certificate of Analysis for Lot # 1781A1A
Certificate of Analysis for Lot # 1784A1
N-HAZ

non-hazardous-statement-anthrax-toxins-64-1

$185.00

#179A (50 ug)

Pertussis Toxin from B. pertussis (in Glycerol)

Info

PERTUSSIS TOXIN from Bordetella pertussis
SIGNAL TRANSDUCTION product information
COA

Current
Certificate of Testing for Lot#179245A1 v.02
Archived
Certificate of Testing for Lot#179244A1 v02
Certificate of Analysis for Lot # 179227A1A
Certificate of Analysis for Lot # 179216A1A
Certificate of Analysis for Lot # 179216A2A
Certificate of Analysis for Lot # 179202A1A
SDS

179-sdsv4-157-1-pdf

$505.00

#180 (50 ug)

Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Info

PERTUSSIS TOXIN from Bordetella pertussis
SIGNAL TRANSDUCTION product information
COA

Current
Certificate of Testing for Lot # 180248A1
Certificate of Testing for Lot # 180246A1
Archived
Certificate of Testing for Lot # 180245A1
Certificate of Testing for Lot # 180244A3
Certificate of Testing for Lot # 180244A1
Certificate of Testing for Lot # 180243A2 v02
Certificate of Analysis for Lot # 180243A1
Certificate of Analysis for Lot # 180242A1 v02
Certificate of Analysis for Lot # 180241A1
Certificate of Analysis for Lot # 180232A1
Certificate of Analysis for Lot # 180235A1A
SDS

180-181-sdsv4-143-1-pdf

$490.00

#181 (50 ug)

Pertussis Toxin from B. pertussis, Lyophilized (Salt-Free)

Info

PERTUSSIS TOXIN from Bordetella pertussis
SIGNAL TRANSDUCTION product information
COA

Current
Certificate of Testing for Lot # 1812427A1
Archived
Certificate of Testing for Lot # 181242A2
Certificate of Testing for Lot # 181244A1
Certificate of Testing for Lot # 181242A1 v03
Certificate of Analysis for Lot # 181238A1
Certificate of Analysis for Lot # 181218A1
Certificate of Analysis for Lot # 181220A1
Certificate of Analysis for Lot # 181241A1
Certificate of Analysis for Lot # 181236A1
SDS

180-181-sdsv4-69-1-pdf

$510.00

#184 (50 ug)

Pertussis Toxin Mutant

This product is discontinued.

Info

PERTUSSIS TOXIN from Bordetella Pertussis
COA

Current
Certificate of Analysis for Lot # 1842A1 v02
N-HAZ

non-hazardous-statement-toxoids-202-1-pdf

#186 (50 ug)

Fimbriae 2/3 from B. pertussis

This product is discontinued.

Info

FIMBRIAE 2/3 FROM BORDETELLA PERTUSSIS
Bordetella Virulence Factors
COA

Current
Certificate of Analysis for Lot # 1865A1
Archived
Certificate of Analysis for Lot # 1863A1
Certificate of Analysis for Lot # 1864C1
N-HAZ

non-hazardous-statement-other-toxins-180-1-pdf

#187 (50 ug)

Pertactin from B. pertussis (69 kDa Protein)

This product is discontinued.

Info

Bordetella Virulence Factors
PERTUSSIS TOXIN from Bordetella pertussis
COA

Current
Certificate of Analysis for Lot # 1876A1 v02
Archived
Certificate of Analysis for Lot # 1874A1
Certificate of Analysis for Lot # 1873A1
Certificate of Analysis for Lot # 1872A1
N-HAZ

non-hazardous-statement-other-toxins-192-1-pdf

#188L (Liquid)

Adenylate Cyclase Toxin, Recombinant from B. pertussis

Info

BORDETELLA VIRULENCE FACTORS PRODUCT INFORMATION
PERTUSSIS TOXIN FROM BORDETELLA PERTUSSIS PRODUCT INFORMATION
ADENYLATE CYCLASE TOXIN PRODUCT BULLETIN
SIGNAL TRANSDUCTION PRODUCT BULLETIN
GENETIC DESCRIPTION
TIPS FOR WORKING WITH ADENYLATE CYCLASE
Adenylate cyclase from B. pertussis, product comparison
COA

Current
Certificate of Testing for Lot # 18810A3
Archived
Certificate of Testing for Lot # 18810A2
Certificate of Analysis for Lot # 18810A1
Certificate of Analysis for Lot # 1889A1
Certificate of Analysis for Lot # 1888A2
Certificate of Analysis for Lot # 1888A3
Certificate of Analysis for Lot # 188L.001
N-HAZ

non-hazardous-statement-other-toxins-158-1-pdf

$490.00

#190A (25 ug), #190B (100 ug),

Tetanus Toxin from Clostridium tetani

Info

TETANUS TOXIN, TETANUS TOXOID, TETANUS LIGHT CHAIN, C-FRAGMENT, FITC C-FRAGMENT AND GST SYNAPTOBREVIN 2 PRODUCT BULLETIN
Protein Carriers for Vaccines
COA

Current
Certificate of Testing for Lot #19050A3
Certificate of Testing for Lot #19050A4
Archived
Certificate of Testing for Lot #19050A3 v02
Certificate of Analysis for Lot # 19050A2
Certificate of Analysis for Lot # 19050A1
Certificate of Analysis for Lot # 19042E1A
Certificate of Analysis for Lot # 19047B1
Certificate of Analysis for Lot # 19042C1
Certificate of Analysis for Lot # 19047A1
SDS

190-sdsv6-73-1-pdf

$270.00 – $870.00

#191A (25 ug), #191B (100 ug),

Tetanus Toxoid from Clostridium tetani

Info

TETANUS TOXIN, TETANUS TOXOID, TETANUS LIGHT CHAIN, C-FRAGMENT, FITC C-FRAGMENT AND GST SYNAPTOBREVIN 2
COA

Current
Certificate of Testing for Lot #19133A5
Certificate of Testing for Lot #19133A3
Certificate of Testing for Lot #19133A4
Archived
Certificate of Testing for Lot # 19133A2
Certificate of Testing for Lot # 19132A2
Certificate of Testing for Lot # 19131A2
Certificate of Testing for Lot # 19132A1 v02
Certificate of Analysis for Lot # 19130A1
Certificate of Analysis for Lot # 19131A1
Certificate of Analysis for Lot # 19127A1
Certificate of Analysis for Lot # 19120A1A
Certificate of Analysis for Lot # 19121A1A
Certificate of Analysis for Lot # 19122A1A
Certificate of Analysis for Lot # 19119A2
Certificate of Analysis for Lot # 19120A1B
Certificate of Analysis for Lot # 19121A1B
Certificate of Analysis for Lot # 19123A1
N-HAZ

non-hazardous-statement-toxoids-75-1-pdf

$460.00 – $1,315.00

#193 (10 ug)

Tetanus Toxin C-Fragment from Clostridium tetani

Info

TETANUS TOXIN, TETANUS TOXOID, TETANUS LIGHT CHAIN, C-FRAGMENT, FITC C-FRAGMENT AND GST SYNAPTOBREVIN 2
COA

Current
Certificate of Analysis for Lot # 19313C1
N-HAZ

non-hazardous-statement-conjugates-77-1-pdf

$750.00

#196A (10 ug)

Tetanus Toxin C-Fragment from Clostridium tetani, FITC Conjugate

This product is discontinued.

COA

Current
Certificate of Analysis for Lot # 1963A1
N-HAZ

non-hazardous-statement-conjugates-78-1-pdf

#201 (5 mg)

LPS from Escherichia coli O111:B4

Info

APOPTOSIS PRODUCT BULLETIN
HIGHLY PURIFIED BACTERIAL LPS PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 20148A1
Archived
Certificate of Testing for Lot # 20147A2
Certificate of Analysis for Lot # 20147A1
Certificate of Analysis for Lot # 20146A1
Certificate of Analysis for Lot # 20144A2
Certificate of Analysis for Lot # 20146A1
Certificate of Analysis for Lot # 20146A2
SDS

201-sdsv1-81-1-pdf

$325.00

#203A (2.5 mg)

LPS from Escherichia coli O55:B5

Info

HIGHLY PURIFIED BACTERIAL LPS PRODUCT BULLETIN
APOPTOSIS PRODUCT BULLETIN
COA

Current
Certificate of Testing for Lot # 20327A4
Certificate of Testing for Lot # 20327A2
Archived
Certificate of Testing for Lot # 20328A1
Certificate of Testing for Lot # 20326A2 v03
Certificate of Testing for Lot # 20326B2 v02
Certificate of Analysis for Lot # 20324A1
Certificate of Analysis for Lot # 20323B1
Certificate of Analysis for Lot # 20323B2
Certificate of Analysis for Lot # 20321A6
SDS

203-sdsv1-82-1-pdf

$345.00

#225 (5 mg)

LPS from Salmonella typhimurium

Info

HIGHLY PURIFIED BACTERIAL LIPOPOLYSACCHARIDES AND RELATED PRODUCTS
APOPTOSIS PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 2258A2
Archived
Certificate of Analysis for Lot # 2258A1
SDS

225-sdsv1-85-1-pdf

$220.00

#301 (5 mg)

LPS from Escherichia coli J5 (Rc)

This product is discontinued.

Info

HIGHLY PURIFIED BACTERIAL LIPOPOLYSACCHARIDES AND RELATED PRODUCTS
APOPTOSIS PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 30131A1
Archived
Certificate of Analysis for Lot # 30130A1
Certificate of Analysis for Lot # 30130A2
SDS

301-sdsv1-86-1-pdf

#302 (5 mg)

LPS from Escherichia coli K12, D31m4 (Re)

Info

HIGHLY PURIFIED BACTERIAL LIPOPOLYSACCHARIDES AND RELATED PRODUCTS
APOPTOSIS PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 3029A1 v03
Archived
Certificate of Analysis for Lot # 3027A1
SDS

302-sdsv1-87-1-pdf

$200.00

#304 (5 mg)

LPS from Salmonella minnesota R595 (Re)

Info

HIGHLY PURIFIED BACTERIAL LIPOPOLYSACCHARIDES AND RELATED PRODUCTS
APOPTOSIS PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 30448A1
Archived
Certificate of Analysis for Lot # 30446A1
SDS

304-sdsv1-88-1-pdf

$200.00

#314 (1 mg)

LPS from Escherichia coli K12 strain LCD25

Info

HIGHLY PURIFIED BACTERIAL LIPOPOLYSACCHARIDES AND RELATED PRODUCTS
COA

Current
Certificate of Analysis for Lot # 3141C1 v02
SDS

314-sdsv1-89-1-pdf

$200.00

#401 (1 mg)

LIPID A monophosphoryl from Salmonella minnesota R595

Info

HIGHLY PURIFIED BACTERIAL LIPOPOLYSACCHARIDES AND RELATED PRODUCTS
COA

Current
Certificate of Analysis for Lot # 40140A1
Archived
Certificate of Analysis for Lot # 40138A
Certificate of Analysis for Lot # 40139A1
SDS

non-hazardous-statement-lps-and-related-91-1-pdf

$240.00

#421 (1 mg)

ULTRA PURE LPS from Escherichia coli O111:B4

This product is discontinued.

Info

HIGHLY PURIFIED BACTERIAL LIPOPOLYSACCHARIDES AND RELATED PRODUCTS
COA

Current
Certificate of Analysis for Lot # 4219A1
Archived
Certificate of Analysis for Lot # 4216A3
Certificate of Analysis for Lot # 4217A1
Certificate of Analysis for Lot # 4218A1
Certificate of Analysis for Lot # 4218A1
SDS

421-sdsv1-92-1-pdf

#423 (1 mg)

ULTRA PURE LPS from Escherichia coli O55:B5

This product is discontinued.

Info

HIGHLY PURIFIED BACTERIAL LIPOPOLYSACCHARIDES AND RELATED PRODUCTS
COA

Current
Certificate of Analysis for Lot # 4231A1
SDS

423-sdsv1-123-1-pdf

#433 (1 mg)

LIST™ HPT™ from Escherichia coli O113

This product is discontinued.

Info

HIGHLY PURIFIED BACTERIAL LIPOPOLYSACCHARIDES AND RELATED PRODUCTS
COA

Current
Certificate of Analysis for Lot # 4331B1 v03
SDS

433-sdsv1-193-1-pdf

#434 (1 mg)

ULTRA PURE LPS from Salmonella minnesota R595 (Re)

Info

APOPTOSIS PRODUCT BULLETIN
HIGHLY PURIFIED BACTERIAL LPS PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 4345A1
Archived
Certificate of Analysis for Lot # 4343A1
Certificate of Analysis for Lot # 4345A1
SDS

434-sdsv1-93-1-pdf

$285.00

#500A (100 ug)

SNAP-25 Recombinant Protein Substrate for C. botulinum Types A and E Neurotoxin

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 5004A1 v02
Archived
Certificate of Analysis for Lot # 5003A1
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-96-1-pdf

$410.00

#520 (200 nmoles)

SNAPtide® Peptide Substrate (o-Abz/Dnp) for C. botulinum Type A Neurotoxin

Info

BOTULINUM NEUROTOXINS PRODUCT BULLETIN
SNAPTIDE, VAMPTIDE, SYNTAXTIDE, AND SNAP ETIDE PRODUCT BULLETIN
COA

Current
Certificate of Testing for Lot 52011A1
Certificate of Testing for Lot 52010A2
Archived
Certificate of Testing for Lot 52010A1
Certificate of Testing for Lot # 5209A5 v01
Certificate of Analysis for Lot # 5209A4 v01
Certificate of Analysis for Lot # 5209A2
Certificate of Analysis for Lot # 5209A1
Certificate of Analysis for Lot # 5209A3
Certificate of Analysis for Lot # 5108A1
Certificate of Analysis for Lot # 5208A3
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-98-1-pdf
Poster

Current
SENSITIVE DETECTION OF BOTULINUM NEUROTOXIN TYPE A USING HIGH AFFINITY POLYCLONAL ANTIBODIES
Comparison of Activity of Botulinum Neurotoxin Type A Holotoxin and Light Chain Using SNAPtide ® FRET Substrates
FRET peptide substrates for the Botulinum toxins type A, B, and E and for anthrax lethal factor
Capture Assay for Botulinum Neurotoxin Type A Utilizing the Neuronal Receptor Protein SV2c
Functional Assay for Botulinum Neurotoxin Type A Utilizing the Neuronal Receptor Protein SV2c
Sensitive, In Vitro, Bifunctional, Potency Assay For Botulinum Neurotoxin Type A
FRET Peptide Substrates for Botulinum Neurotoxins Types A, B, C, and E
EVALUATION OF A SMALL PEPTIDE INHIBITOR AND A CONTROL PEPTIDE FOR BOTULINUM NEUROTOXIN, TYPE A
ULTRA SENSITIVE HPLC DETECTION ASSAY FOR BOTULINUM NEUROTOXIN TYPE A
NEW SV2c CONSTRUCT FOR USE IN BINDING AND DETECTING BOUTULINUM NEUROTOXIN TYPE A
SENSITIVE AND SPECIFIC BIFUNCTIONAL ASSAY FOR BOTULINUM NEUROTOXIN TYPE A

$970.00

#521 (200 nmoles)

SNAPtide® Peptide Substrate (FITC/DABCYL) for C. botulinum Type A Neurotoxin

This product is discontinued.

Info

BOTULINUM NEUROTOXINS PRODUCT BULLETIN
SNAPTIDE, VAMPTIDE, SYNTAXTIDE, AND SNAP ETIDE PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 5214A3 v02
Archived
Certificate of Analysis for Lot # 5213A2
Certificate of Analysis for Lot # 5214A2
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-99-1-pdf
Poster

Current
EVALUATION OF A SMALL PEPTIDE INHIBITOR AND A CONTROL PEPTIDE FOR BOTULINUM NEUROTOXIN, TYPE A
FRET Peptide Substrates for Botulinum Neurotoxins Types A, B, C, and E
Comparison of Activity of Botulinum Neurotoxin Type A Holotoxin and Light Chain Using SNAPtide ® FRET Substrates
NEW FRET SUBSTRATE FOR BOTULINUM NEUROTOXIN TYPE A
FRET peptide substrates for the Botulinum toxins type A, B, and E and for anthrax lethal factor

#523 (200 nmoles)

SNAPtide® Peptide Substrate flP6(DABCYL/5-IAF) for C. botulinum Type A Neurotoxin

Info

BOTULINUM NEUROTOXINS
COA

Current
Certificate of Analysis for Lot # 5232A1 v02
Archived
Certificate of Analysis for Lot # 5231A1
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-183-1
Poster

Current
NEW FRET SUBSTRATE FOR BOTULINUM NEUROTOXIN TYPE A

$600.00

#525 (200 nmoles)

Control Peptide for SNAPtide® 520 Substrate for C. botulinum Type A Neurotoxin

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 5252A1 v02
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-169-1-pdf
Poster

Current
EVALUATION OF A SMALL PEPTIDE INHIBITOR AND A CONTROL PEPTIDE FOR BOTULINUM NEUROTOXIN, TYPE A

$600.00

#526 (200 nmoles)

Control Peptide for SNAPtide® 521 for C. botulinum Type A Neurotoxin

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 5261A1 v02
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-186-1-pdf

$600.00

#528 (50 nmoles)

Unquenched Calibration Peptide for SNAPtide® 521 Substrate for C. botulinum Type A Neurotoxin

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 5281A2
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-100-1-pdf
Poster

Current
NEW FRET SUBSTRATE FOR BOTULINUM NEUROTOXIN TYPE A
Comparison of Activity of Botulinum Neurotoxin Type A Holotoxin and Light Chain Using SNAPtide ® FRET Substrates

#529 (50 nmoles)

Unquenched Calibration Peptide for SNAPtide® 520 Substrate for C. botulinum Type A Neurotoxin

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 5292A2 v02
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-101-1-pdf
Poster

Current
SENSITIVE AND SPECIFIC BIFUNCTIONAL ASSAY FOR BOTULINUM NEUROTOXIN TYPE A
Comparison of Activity of Botulinum Neurotoxin Type A Holotoxin and Light Chain Using SNAPtide ® FRET Substrates

$250.00

#530 (200 nmoles)

MAPKKide® Peptide Substrate (o-Abz/Dnp) for Anthrax Lethal Factor

Product # 530 is MAPKKide® utilizing the o-Abz/Dnp FRET pair. A calibration peptide, Product #539 is available for convenient use with the quenched substrate.

Info

MAPKKIDE PLUS PRODUCT BULLETIN
ANTHRAX TOXIN PRODUCT BULLETIN
MAPKKIDE PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 5303A6
Certificate of Analysis for Lot # 5303A5
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-102-1-pdf
Poster

Current
Internally Quenched Fluorogenic Substrates for Anthrax Lethal Factor
Physical Characteristics of rLF and rPA: Effects on Enzymatic Activity and Binding
FRET Peptide Substrates for the Botulinum Toxins Type A, B, and E and for Anthrax Lethal Factor

$365.00

#531 (200 nmoles)

MAPKKide® Peptide Substrate (DABCYL/FITC) for Anthrax Lethal Factor

This product is discontinued.Product # 531 is MAPKKide® with the FRET pair DABCYL/FITC.

Info

MAPKKIDE PLUS PRODUCT BULLETIN
ANTHRAX TOXIN PRODUCT BULLETIN
MAPKKIDE PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 5313A1
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-103-1-pdf
Poster

Current
FRET peptide substrates for the Botulinum toxins type A, B, and E and for anthrax lethal factor

#532 (100 nmoles)

MAPKKide® Plus (AMC) Specific Substrate for Anthrax Lethal Factor

Product # 532 is MAPKKide® Plus Specific Substrate for Anthrax Lethal Factor. This peptide is remarkable in its resistance to non-specific cleavage by enzymes which may be present in natural samples. MAPKKide® Plus carries the fluorophore 7-amido-4-methylcoumarin (AMC).

Info

MAPKKIDE PRODUCT BULLETIN
MAPKKIDE PLUS PRODUCT BULLETIN
ANTHRAX TOXIN PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 5321A1
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-251-1-pdf
Poster

Current
Sensitive Detection of Anthrax Lethal Factor in Plasma Using a Specific Biotinylated Fluorogenic Substrate
MAPKKide® Plus: A Specific Substrate for Sensitive Detection of Anthrax Lethal Factor in Complex Matrices
Fluorescence Substrate for Specific and Quantitative Detection of Anthrax Lethal Factor in Plasma
Substrate for Specific Lethal Factor
Specific Detection of Anthrax Infection

$305.00

#539 (50 nmoles)

Unquenched Calibration Peptide for MAPKKide® 530 for Anthrax Lethal Factor

This product is discontinued.

Info

MAPKKIDE PLUS PRODUCT BULLETIN
ANTHRAX TOXIN PRODUCT BULLETIN
MAPKKIDE PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 5391A2
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-104-1-pdf
Poster

Current
Physical Characteristics of rLF and rPA: Effects on Enzymatic Activity and Binding

#540 (200 nmoles)

VAMPtide® Peptide Substrate (o-Abz/Dnp) Substrate for C. botulinum Type B Neurotoxin

This product is discontinued.

Info

BOTULINUM NEUROTOXINS PRODUCT BULLETIN
SNAPTIDE, VAMPTIDE, SYNTAXTIDE, AND SNAP ETIDE PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 5404A1
Archived
Certificate of Analysis for Lot # 5403A1
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-105-1-pdf
Poster

Current
EVALUATION OF THREE VAMPTIDE® SUBSTRATES FOR BOTULINUM NEUROTOXIN TYPE B
FRET Peptide Substrates for Botulinum Neurotoxins Types A, B, C, and E
FRET peptide substrates for the Botulinum toxins type A, B, and E and for anthrax lethal factor
Comparison of Activity of Botulinum Neurotoxin Type A Holotoxin and Light Chain Using SNAPtide ® FRET Substrates

#541 (200 nmoles)

VAMPtide® Peptide Substrate (FITC/DABCYL) Substrate for C. botulinum Type B Neurotoxin

Info

BOTULINUM NEUROTOXINS PRODUCT BULLETIN
SNAPTIDE, VAMPTIDE, SYNTAXTIDE, AND SNAP ETIDE PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 5411A1 v02
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-170-1-pdf
Poster

Current
EVALUATION OF THREE VAMPTIDE® SUBSTRATES FOR BOTULINUM NEUROTOXIN TYPE B

$600.00

#542 (200 nmoles)

VAMPtide® (Pya/Nop) Peptide Substrate for Botulinum Neurotoxin Type B

Info

BOTULINUM NEUROTOXINS
FRET Peptides Native Substrates and Receptors
COA

Current
Certificate of Analysis for Lot # 5421A1
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-190-1-pdf
Poster

Current
EVALUATION OF THREE VAMPTIDE® SUBSTRATES FOR BOTULINUM NEUROTOXIN TYPE B

$600.00

#549 (100 nmoles)

Calibration Fluorophore for VAMPtide® 540 Substrate for C. botulinum Type B Neurotoxin

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 5491A1
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-147-1-pdf

$205.00

#550 (100 nmoles)

SNAP Etide® Peptide Substrate (o-Abz/Dnp) for C. botulinum Type E Neurotoxin

This product is discontinued.

Info

BOTULINUM NEUROTOXINS PRODUCT BULLETIN
SNAPTIDE, VAMPTIDE, SYNTAXTIDE, AND SNAP ETIDE PRODUCT BULLETIN
COA

Archived
Certificate of Testing for Lot # 5504A1
Certificate of Analysis for Lot # 5503A1 v02
Certificate of Analysis for Lot # 5502A1
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-106-1-pdf
Poster

Current
FRET Peptide Substrates for Botulinum Neurotoxins Types A, B, C, and E
SNAP EtideTM, a FRET Substrate for BotulinumToxin Type E
FRET peptide substrates for the Botulinum toxins type A, B, and E and for anthrax lethal factor

#559 (50 nmoles)

Unquenched Calibration Peptide for SNAP Etide® Prod #550

COA

Current
Certificate of Analysis for Lot # 5591A1 v02
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-256-1-pdf

$290.00

#560 (200 nmoles)

SYNTAXtide® (o-Abz/Dnp) Peptide Substrate for C. botulinum Type C Neurotoxin

Info

BOTULINUM NEUROTOXINS PRODUCT BULLETIN
SNAPTIDE, VAMPTIDE, SYNTAXTIDE, AND SNAP ETIDE PRODUCT BULLETIN
COA

Current
Certificate of Analysis for Lot # 5602A1
N-HAZ

non-hazardous-statement-fret-peptide-native-substrates-and-receptors-144-1-pdf
Poster

Current
Ultra Sensitive HPLC Detection Assay for Botulinum Neurotoxin Type A
FRET Peptide Substrates for Botulinum Neurotoxins Types A, B, C, and E

$555.00

#611A (15 ug)

Botulinum Neurotoxin Type A Light Chain, Recombinant, GST Fusion

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 6112A1
Archived
Certificate of Analysis for Lot # 6111A1
N-HAZ

non-hazardous-statement-recombinant-chains-23-1-pdf

$310.00

#612A (50 ug)

Botulinum Neurotoxin Type A Heavy Chain, Recombinant, Binding Domain

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 6123A1
Archived
Certificate of Analysis for Lot # 6121A1
Certificate of Analysis for Lot # 6122A1
N-HAZ

non-hazardous-statement-recombinant-chains-153-1-pdf
Poster

Current
New High Affinity Antibodies Against Botulinum Neurotoxin Type A

#613A (50 ug)

Botulinum Neurotoxin Type A Heavy Chain, Recombinant, Binding Domain, GST Fusion

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 6131B1
N-HAZ

non-hazardous-statement-recombinant-chains-149-1-pdf

#620A (10 ug)

Botulinum Neurotoxin Type B Light Chain, Recombinant

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 62015A1
Archived
Certificate of Analysis for Lot # 6206A1
N-HAZ

non-hazardous-statement-recombinant-chains-24-1-pdf
Poster

Current
EVALUATION OF THREE VAMPTIDE® SUBSTRATES FOR BOTULINUM NEUROTOXIN TYPE B
FRET Peptide Substrates for Botulinum Neurotoxins Types A, B, C, and E
Comparison of Activity of Botulinum Neurotoxin Type A Holotoxin and Light Chain Using SNAPtide ® FRET Substrates

$555.00

#622A (50 ug)

Botulinum Neurotoxin Type B Heavy Chain, Recombinant, Binding Domain

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 6222A1
Archived
Certificate of Analysis for Lot # 6221A1
N-HAZ

non-hazardous-statement-recombinant-chains-152-1-pdf

#623A (50 ug)

Botulinum Neurotoxin Type B Heavy Chain, Recombinant, Binding Domain, GST Fusion

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 6231A1
N-HAZ

non-hazardous-statement-recombinant-chains-150-1-pdf

#625A (10 ug)

Botulinum Neurotoxin Type C Light Chain, Recombinant

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 6256A1
Archived
Certificate of Analysis for Lot # 6253A1
N-HAZ

non-hazardous-statement-recombinant-chains-25-1-pdf
Poster

Current
FRET Peptide Substrates for Botulinum Neurotoxins Types A, B, C, and E
Ultra Sensitive HPLC Detection Assay for Botulinum Neurotoxin Type A

$555.00

#630A (10 ug)

Botulinum Neurotoxin Type D Light Chain, Recombinant

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 6301A1 v02
N-HAZ

non-hazardous-statement-recombinant-chains-26-1-pdf

#690B (100 ug)

Receptor for Clostridium botulinum Type A Neurotoxin, GST-SV2c luminal domain

This product is discontinued.

Info

Technical Info
COA

Archived
Certificate of Testing for Lot # 6906A1
Certificate of Analysis for Lot # 6905A1
Certificate of Analysis for Lot # 6904A1
Certificate of Analysis for Lot # 6902A1
N-HAZ

non-hazardous-statement-recombinant-chains-194-1-pdf
Poster

Current
SENSITIVE AND SPECIFIC BIFUNCTIONAL ASSAY FOR BOTULINUM NEUROTOXIN TYPE A
Ultra Sensitive HPLC Detection Assay for Botulinum Neurotoxin Type A
Functional Assay for Botulinum Neurotoxin Type A Utilizing the Neuronal Receptor Protein SV2c
Capture Assay for Botulinum Neurotoxin Type A Utilizing the Neuronal Receptor Protein SV2c
Sensitive, In Vitro, Bifunctional, Potency Assay For Botulinum Neurotoxin Type A

#703 (0.1 ml)

Anti-Cholera Toxin B Subunit (Goat)

Info

FITC AND BIOTIN CONJUGATES OF CHOLERA TOXIN B SUBUNIT
CHOLERA TOXIN PRODUCT BULLETIN
COA

Current
Certificate of Testing for Lot # 7032A12
Certificate of Testing for Lot # 7032A11
Archived
Certificate of Analysis for Lot # 7032A10
Certificate of Analysis for Lot # 7032A9
Certificate of Analysis for Lot # 7032A6
Certificate of Analysis for Lot # 7032A7
Certificate of Analysis for Lot # 7032A8
N-HAZ

non-hazardous-statement-antisera-and-antibodies-110-1-pdf

$320.00

#730A (0.1 mg)

Anti-Botulinum Neurotoxin, Type A (Chicken lgY)

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Testing for Lot # 7304A1
Archived
Certificate of Analysis for Lot # 7303A1
Certificate of Analysis for Lot # 7302A1
Certificate of Analysis for Lot # 7302B2
Certificate of Analysis for Lot # 7302A1
N-HAZ

non-hazardous-statement-antisera-and-antibodies-140-1-pdf
Poster

Current
New High Affinity Antibodies Against Botulinum Neurotoxin Type A
SENSITIVE DETECTION OF BOTULINUM NEUROTOXIN TYPE A USING HIGH AFFINITY POLYCLONAL ANTIBODIES

#731L (0.1 mg)

Anti-Botulinum Neurotoxin, Type A (Mouse lgG monoclonal F1-40), Frozen Liquid

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 7311A2 v02
N-HAZ

non-hazardous-statement-antisera-and-antibodies-197-1-pdf
Poster

Current
New High Affinity Antibodies Against Botulinum Neurotoxin Type A
ULTRA SENSITIVE HPLC DETECTION ASSAY FOR BOTULINUM NEUROTOXIN TYPE A

$435.00

#752 (0.5 ml)

Anti-Toxin A from Clostridium difficile (Goat)

This product is discontinued.

Info

C. DIFFICILE TOXINS PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Analysis for Lot # 7521A2 v02
Archived
Certificate of Analysis for Lot # 7521A
N-HAZ

non-hazardous-statement-antisera-and-antibodies-111-1-pdf

#753A (0.1 mg)

Anti-Clostridium difficile Toxin A (Chicken lgY)

This product is discontinued.

Info

C. DIFFICILE TOXINS PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Analysis for Lot # 7531A2
Archived
Certificate of Analysis for Lot # 7531A1
N-HAZ

non-hazardous-statement-antisera-and-antibodies-160-1-pdf

#754A (0.1 mg)

Anti-Clostridium difficile Toxin B (Chicken lgY)

This product is discontinued.

Info

C. DIFFICILE TOXINS PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Analysis for Lot # 7542A1
N-HAZ

non-hazardous-statement-antisera-and-antibodies-196-1-pdf

#756A (0.1 mg)

Anti-Glutamate Dehydrogenase from Clostridium difficile lgY

This product is discontinued.

Info

C. DIFFICILE TOXINS PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Analysis for Lot # 7561A2
N-HAZ

non-hazardous-statement-antisera-and-antibodies-223-1-pdf

#757A (0.1 mg)

Anti-Clostridium difficile Binary Toxin A subunit (Chicken lgY)

This product is discontinued.

Info

C. DIFFICILE TOXINS PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Analysis for Lot # 7572A1
Archived
Certificate of Analysis for Lot # 7571A1
N-HAZ

non-hazardous-statement-antisera-and-antibodies-221-1-pdf

#758A (0.1 mg)

Anti-Clostridium difficile Binary Toxin B Subunit (Chicken lgY)

This product is discontinued.

Info

C. DIFFICILE TOXINS PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Analysis for Lot # 7582A1
Archived
Certificate of Analysis for Lot # 7581A1
N-HAZ

non-hazardous-statement-antisera-and-antibodies-212-1-pdf

#759A (0.1 mg)

Biotinylated Anti-Clostridium difficile Binary Toxin B Subunit (Chicken lgY)

This product is discontinued.

Info

C. DIFFICILE TOXINS PRODUCT BULLETIN
C difficile Family of Products
COA

Current
Certificate of Analysis for Lot # 7591A1
N-HAZ

non-hazardous-statement-antisera-and-antibodies-213-1-pdf

#761L (Liquid)

Anti-Shiga Toxin 1, Rabbit lgG

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 7611A1
N-HAZ

non-hazardous-statement-antisera-and-antibodies-248-1-pdf

#766L (Liquid)

Anti-Shiga Toxin, Camelid Antibody, VHH

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 7661A1
N-HAZ

non-hazardous-statement-antisera-and-antibodies-246-1-pdf

#768L (Liquid)

Anti-B. anthracis Lethal Factor (LF-A), lgY Antibody, Biotinylated

Product # 768L affinity purified and biotinylated Anti-Lethal Factor from B. anthracis (chicken lgY) works to detect the LF as described in the C of A.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 7681A1
N-HAZ

non-hazardous-statement-antisera-and-antibodies-245-1-pdf

$415.00

#771B (1 mg)

Anti-Protective Antigen from B. anthracis (Goat)

This product is discontinued.Products # 771, purified IgG from goat, is directed to PA.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 7712A3
Certificate of Analysis for Lot # 7712A2
Archived
Certificate of Analysis for Lot # 7711A6
Certificate of Analysis for Lot # 7712A1
N-HAZ

non-hazardous-statement-antisera-and-antibodies-115-1-pdf

#773L (Liquid)

Anti-Edema Factor from B. anthracis (Goat)

This product is discontinued.

Info

Technical Info
COA

Current
Certificate of Analysis for Lot # 7732A3
N-HAZ

non-hazardous-statement-antisera-and-antibodies-117-1-pdf

Beta-defensins activate macrophages and synergize in pro-inflammatory cytokine expression induced by TLR ligands

Immunobiology

Barabas, N;Rhrl, J;Holler, E;Hehlgans, T;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Our previous studies indicated that mouse beta defensin 14 (mBD14, Defb14), a newly identified membe....

Inhibitory effects of tocopherols on expression of the cyclooxygenase-2 gene in RAW264.7 cells stimulated by lipopolysaccharide, tumor necrosis factor- or Porphyromonas gingivalis fimbriae

In Vivo

Murakami, Y;Kawata, A;Koh, T;Seki, Y;Tamura, S;Katayama, T;Fujisawa, S;

Product: LPS from Escherichia coli O111:B4

Tocopherols, which include -, -, -, and -tocopherol, protect cells against harmful free radicals and....

Anti-bacterial and anti-toxic immunity induced by a killed whole-cell-cholera toxin B subunit cholera vaccine is essential for protection against lethal bacterial infection in mouse pulmonary cholera model

Mucosal Immunology

Kang, SS;Yang, JS;Kim, KW;Yun, CH;Holmgren, J;Czerkinsky, C;Han, SH;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

The lack of appropriate animal model for studying protective immunity has limited vaccine developmen....

Immunisation of mares with binding domains of toxins A and B of Clostridium difficile elicits serum and colostral antibodies that block toxin binding

Equine Veterinary Journal

Artiushin, S;Timoney, JF;Fettinger, M;Fallon, L;Rathgeber, R;

Product: Toxin A from Clostridium difficile

Enterocolitis caused by Clostridium difficile (C. difficile) is a serious, sometimes fatal, disease ....

Detection of Clostridium difficile toxins A, B and binary toxin with slow off-rate modified aptamers

Diagnostic Microbiology And Infectious Disease

Ochsner, UA;Katilius, E;Janjic, N;

Product: Toxin B from Clostridium difficile

Rapid and accurate diagnostic tests for Clostridium difficile infections (CDI) are crucial for manag....

Characterization of the native form of anthrax lethal factor for use in the toxin neutralization assay

Clinical And Vaccine Immunology

Lu, H;Catania, J;Baranji, K;Feng, J;Gu, M;Lathey, J;Sweeny, D;Sanford, H;Sapru, K;Patamawenu, T;Chen, JH;Ng, A;Fesseha, Z;Kluepfel-Stahl, S;Minang, J;Alleva, D;

Product: Anthrax Lethal Factor (LF), Recombinant from B. anthracis

The cell-based anthrax toxin neutralization assay (TNA) is used to determine functional antibody tit....

Neutralization of B. anthracis toxins during ex vivo phagocytosis

Glycoconjugate Journal

Tarasenko, O;Scott, A;Jones, A;Soderberg, L;Alusta, P;

Product: Anthrax Edema Factor (EF), Recombinant from B. anthracis

Glycoconjugates (GCs) are recognized as stimulation and signaling agents, affecting cell adhesion, a....

In-depth analysis of hyaline fibromatosis syndrome frameshift mutations at the same site reveal the necessity of personalized therapy

Human Mutation

Yan, SE;Lemmin, T;Salvi, S;Lausch, E;Superti-Furga, A;Rokicki, D;Dal Peraro, M;van der Goot, FG;

Product: Anti-Protective Antigen from B. anthracis (Goat)

Hyaline fibromatosis syndrome is an autosomal recessive disease caused by mutations in ANTXR2, a gen....

Single-step grafting of aminooxy-peptides to hyaluronan: a simple approach to multifunctional therapeutics for experimental autoimmune encephalomyelitis

Journal of Controlled Release

Sestak, J;Mullins, M;Northrup, L;Thati, S;Forrest, ML;Siahaan, TJ;Berkland, C;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

The immune response to antigens is directed in part by the presence or absence of costimulatory sign....

Plastic changes in lumbar segments after thoracic spinal cord injuries in adult rats: an integrative view of spinal nociceptive dysfunctions

Restorative Neurology And Neuroscience

Redondo-Castro, E;Garca-Alas, G;Navarro, X;

Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

Spinal cord injuries (SCI) cause motor, sensory and autonomic dysfunctions as well as neuropathic pa....

Perforin deficiency impairs a critical immunoregulatory loop involving murine CD8(+) T cells and dendritic cells

Blood

Terrell, CE;Jordan, MB;

Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae

Humans and mice with impaired perforin-dependent cytotoxic function may develop excessive T-cell act....

Omega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation

Immunity

Yan, Y;Jiang, W;Spinetti, T;Tardivel, A;Castillo, R;Bourquin, C;Guarda, G;Tian, Z;Tschopp, J;Zhou, R;

Product: Anthrax Protective Antigen (PA), Recombinant from B. anthracis

Omega-3 fatty acids (-3 FAs) have potential anti-inflammatory activity in a variety of inflammatory ....

Complement C3a signaling mediates production of angiogenic factors in mesenchymal stem cells

Journal Of Biomedical Science And Engineering

DiScipio, RG;Khaldoyanidi, SK;Moya-Castro, R;Schraufstatter, IU;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

A major portion of the beneficial effect of mesenchymal stem cells (MSC) is due to the production of....

Efeitos da senescncia no ncleo supraquiasmtico do sagui (Callithrix Jacchus): plasticidade morfolgica e neuroqumica

Thesis

Engelberth, RCGJ;

Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

Effects of administration of live or inactivated virulent Rhodococccus equi and age on the fecal microbiome of neonatal foals

PLoS ONE

Bordin, AI;Suchodolski, JS;Markel, ME;Weaver, KB;Steiner, JM;Dowd, SE;Pillai, S;Cohen, ND;

Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

Rhodococcus equi is an important pathogen of foals. Enteral administration of live, virulent R. equi....

B7-H5 costimulates human T cells via CD28H.

Nature Communications

Zhu, Y;Yao, S;Iliopoulou, BP;Han, X;Augustine, MM;Xu, H;Phennicie, RT;Flies, SJ;Broadwater, M;Ruff, W;Taube, JM;Zheng, L;Luo, L;Zhu, G;Chen, J;Chen, L;

Product: Tetanus Toxin from Clostridium tetani

The B7/CD28 family has profound modulatory effects in immune responses and constitutes an important ....

Dendritic peptide release mediates interpopulation crosstalk between neurosecretory and preautonomic networks

Neuron

Son, SJ;Filosa, JA;Potapenko, ES;Biancardi, VC;Zheng, H;Patel, KP;Tobin, VA;Ludwig, M;Stern, JE;

Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

Although communication between neurons is considered a function of the synapse, neurons also release....

Pertussis toxin attenuates experimental autoimmune encephalomyelitis by upregulating neuronal vascular endothelial growth factor

NeuroReport

Tang, Z;Yin, JX;Han, P;Gan, Y;Coons, SW;Wang, C;Maalouf, M;Shi, J;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

We have reported earlier that pertussis toxin (PTx) attenuates the motor deficits in experimental au....

Human astrocytes derived from glial restricted progenitors support regeneration of the injured spinal cord

Journal Of Neurotrauma

Haas, C;Fischer, I;

Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

Cellular transplantation using neural stem cells and progenitors is a promising therapeutic strategy....

Neural pathways mediating control of reproductive behavior in male Japanese quail

The Journal of Comparative Neurology

Wild, JM;Balthazart, J;

Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

The sexually dimorphic medial preoptic nucleus (POM) in Japanese quail has for many years been the f....

Characterization of migration parameters on peripheral and central nervous system T cells following treatment of experimental allergic encephalomyelitis with CRYAB

Journal Of Neuroimmunology

Oyebamiji, AI;Finlay, TM;Hough, RM;Hoghooghi, V;Lim, EM;Wong, CH;Ousman, SS;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

CRYAB, a small heat shock protein, was previously shown to decrease neuroinflammation in experimenta....

Virus-induced CD8+ T cells accelerate the onset of experimental autoimmune encephalomyelitis: implications for how viral infections might trigger multiple sclerosis exacerbations

Journal Of Neuroimmunology

Rainey-Barger, EK;Blakely, PK;Huber, AK;Segal, BM;Irani, DN;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Viral infections can exacerbate multiple sclerosis (MS) through poorly defined mechanisms. We develo....

Role of macrophage receptor with collagenous structure in innate immune tolerance

The Journal of Immunology

Jing, J;Yang, IV;Hui, L;Patel, JA;Evans, CM;Prikeris, R;Kobzik, L;O'Connor, BP;Schwartz, DA;

Product: ULTRA PURE LPS from Escherichia coli O111:B4

Macrophages play a key role in host defense against microbes, in part, through phagocytosis. Macroph....

Characterization of multiple bistratified retinal ganglion cells in a purkinje cell protein 2-Cre transgenic mouse line

The Journal of Comparative Neurology

Ivanova, E;Lee, P;Pan, ZH;

Product: Anti-Cholera Toxin B Subunit (Goat)

Retinal ganglion cells are categorized into multiple classes, including multiple types of bistratifi....

Prenatal passive transfer of maternal immunity in Asian elephants (Elephas maximus)

Veterinary Immunology And Immunopathology

Nofs, SA;Atmar, RL;Keitel, WA;Hanlon, C;Stanton, JJ;Tan, J;Flanagan, JP;Howard, L;Ling, PD;

Product: Tetanus Toxoid from Clostridium tetani

Asian (Elephas maximus) and African (Loxodonta africana) elephants exhibit characteristics of endoth....

Ascending and descending propriospinal pathways between lumbar and cervical segments in the rat: evidence for a substantial ascending excitatory pathway

Neuroscience

Brockett, EG;Seenan, PG;Bannatyne, BA;Maxwell, DJ;

Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

Precise mechanisms are required to coordinate the locomotor activity of fore- and hind-limbs in quad....

Discrete melanocortin-sensitive neuroanatomical pathway linking the ventral premmamillary nucleus to the paraventricular hypothalamus

Neuroscience

Gautron, L;Cravo, RM;Elmquist, JK;Elias, CF;

Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

The physiological effects of melanocortin-4 receptor (MC4-R) on metabolism have been hypothesized to....

RIP1-driven autoinflammation targets IL-1 independently of inflammasomes and RIP3

Nature

Lukens, JR;Vogel, P;Johnson, GR;Kelliher, MA;Iwakura, Y;Lamkanfi, M;Kanneganti, TD;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

The protein-tyrosine phosphatase SHP-1 has critical roles in immune signalling, but how mutations in....

Barrelettes without barrels in the American water shrew

PLoS ONE

Catania, KC;Catania, EH;Sawyer, EK;Leitch, DB;

Product: Anti-Cholera Toxin B Subunit (Goat)

Water shrews (Sorex palustris) depend heavily on their elaborate whiskers to navigate their environm....

CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells

PNAS

Slater, LH;Hett, EC;Clatworthy, AE;Mark, KG;Hung, DT;

Product: Anthrax Edema Factor (EF), Recombinant from B. anthracis

Bacterial toxins have evolved successful strategies for coopting host proteins to access the cytosol....

Nasal immunization with the 40-kDa outer membrane protein of Porphyromonas gingivalis plus cholera toxin induces protective immunity in aged mice

Journal Of Oral Science

Cai, Y;Kurita-Ochiai, T;Kobayashi, R;Hashizume, T;Yamamoto, M;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

Previous studies have demonstrated that nasal administration of the outer membrane protein of Porphy....

Mapping the epitopes of a neutralizing antibody fragment directed against the lethal factor of Bacillus anthracis and cross-reacting with the homologous edema factor

PLoS ONE

Thullier, P;Avril, A;Mathieu, J;Behrens, CK;Pellequer, JL;Pelat, T;

Product: Anthrax Edema Factor (EF), Recombinant from B. anthracis

The lethal toxin (LT) of Bacillus anthracis, composed of the protective antigen (PA) and the lethal ....

Active suppression induced by repetitive self-epitopes protects against EAE development

PLoS ONE

Puentes, F;Dickhaut, K;Hofsttter, M;Falk, K;Rtzschke, O;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Autoimmune diseases result from a breakdown in self-tolerance to autoantigens. Self-tolerance is ind....

Amygdala lesions reduce cataplexy in orexin knock-out mice

The Journal of Neuroscience

Burgess, CR;Oishi, Y;Mochizuki, T;Peever, JH;Scammell, TE;

Product: Anti-Cholera Toxin B Subunit (Goat)

Narcolepsy is characterized by excessive sleepiness and cataplexy, sudden episodes of muscle weaknes....

Arid5a controls IL-6 mRNA stability, which contributes to elevation of IL-6 level in vivo

PNAS

Masuda, K;Ripley, B;Nishimura, R;Mino, T;Takeuchi, O;Shioi, G;Kiyonari, H;Kishimoto, T;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Posttranscriptional regulation of IL-6 has been largely uncharacterized, with the exception of the r....

Substrates and controls for the quantitative detection of active botulinum neurotoxin in protease-containing samples

Analytical Chemistry

Bagramyan, K;Kaplan, BE;Cheng, LW;Strotmeier, J;Rummel, A;Kalkum, M;

Product: SNAPtide® Peptide Substrate (FITC/DABCYL) for C. botulinum Type A Neurotoxin

Botulinum neurotoxins (BoNTs) are used in a wide variety of medical applications, but there is limit....

Retinorecipient areas in the diurnal murine rodent Arvicanthis niloticus: A disproportionally large superior colliculus.

The Journal of Comparative Neurology

Gaillard, F;Karten, HJ;Sauv, Y;

Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

The Nile grass rat (Arvicanthis niloticus) has a high proportion of cone photoreceptors (30-40%) com....

Macrophages are essential for the early wound healing response and the formation of a fibrovascular scar

The American Journal Of Pathology

He, L;Marneros, AG;

Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae

After wounding, multiple cell types interact to form a fibrovascular scar; the formation and cellula....

High-mobility group box 1 protein (HMGB1) neutralization ameliorates experimental autoimmune encephalomyelitis

Journal of Autoimmunity

Robinson, AP;Caldis, MW;Harp, CT;Goings, GE;Miller, SD;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Multiple sclerosis (MS) is an autoimmune, demyelinating disease and as such, the gold standard of tr....

Copper/zinc chelation by clioquinol reduces spinal cord white matter damage and behavioral deficits in a murine MOG-induced multiple sclerosis model

Neurobiology of Disease

Choi, BY;Jang, BG;Kim, JH;Seo, JN;Wu, G;Sohn, M;Chung, TN;Suh, SW;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

The present study aimed to evaluate the therapeutic potential of clioquinol (CQ), a metal chelator, ....

Progression in multiple sclerosis is associated with low endogenous NCAM

Journal Of Neurochemistry

Gnanapavan, S;Ho, P;Heywood, W;Jackson, S;Grant, D;Rantell, K;Keir, G;Mills, K;Steinman, L;Giovannoni, G;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Multiple sclerosis (MS) is a CNS disorder characterized by demyelination and neurodegeneration. Alth....

Elevation of tumor necrosis factor in dorsal root ganglia and spinal cord is associated with neuroimmune modulation of pain in an animal model of multiple sclerosis

Journal of Neuroimmune Pharmacology

Begum, F;Zhu, W;Cortes, C;MacNeil, B;Namaka, M;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Neuropathic pain (NPP) is a frequently reported symptom described by 50-80% of multiple sclerosis (M....

Podoplanin is an inflammatory protein upregulated in Th17 cells in SKG arthritic joints

Molecular Immunology

Miyamoto, Y;Uga, H;Tanaka, S;Kadowaki, M;Ikeda, M;Saegusa, J;Morinobu, A;Kumagai, S;Kurata, H;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Interleukin 17-producing helper T (Th17) cells play pathogenic roles in chronic inflammatory and aut....

A modified superantigen rescues Ly6G- CD11b+ blood monocyte suppressor function and suppresses antigen-specific inflammation in EAE

Autoimmunity

Slaney, CY;Toker, A;Fraser, JD;Harper, JL;Bckstrm, BT;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

In a previous study, we showed that the Ly6G(-)CD11b(+) blood monocytes residing in nave mice are in....

Macromolecule Permeability in Rodent Intestine following Thermal Injury and Lipopolysaccharide Challenge

ISRN Physiology

Yu, P;Carter, EA;

Product: LPS from Escherichia coli O111:B4

The barrier function of the intestinal mucosa may be lost during stress such as severe trauma and se....

Infection of macrophages with Mycobacterium tuberculosis induces global modifications to phagosomal function

Cellular Microbiology

Podinovskaia, M;Lee, W;Caldwell, S;Russell, DG;

Product: ULTRA PURE LPS from Salmonella minnesota R595 (Re)

The phagosome is a central mediator of both the homeostatic and microbicidal functions of a macropha....

The sirtuin inhibitor cambinol impairs MAPK signaling, inhibits inflammatory and innate immune responses and protects from septic shock

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Lugrin, J;Ciarlo, E;Santos, A;Grandmaison, G;dos Santos, I;Le Roy, D;Roger, T;

Product: ULTRA PURE LPS from Salmonella minnesota R595 (Re)

Sirtuins (SIRT1-7) are NAD(+)-dependent histone deacetylases (HDACs) that play an important role in ....

Toll-like receptor 5-dependent immunogenicity and protective efficacy of a recombinant fusion protein vaccine containing the nontoxic domains of Clostridium difficile toxins A and B and Salmonella enterica serovar typhimurium flagellin in a mouse model of

Infection And Immunity

Ghose, C;Verhagen, JM;Chen, X;Yu, J;Huang, Y;Chenesseau, O;Kelly, CP;Ho, DD;

Product: Anti-Toxin A from Clostridium difficile (Goat)

Clostridium difficile is a spore-forming bacillus that produces toxin-mediated enteric disease. C. d....

Arsenic inhibits autophagic flux, activating the Nrf2-Keap1 pathway in a p62-dependent manner

Molecular And Cellular Biology

Lau, A;Zheng, Y;Tao, S;Wang, H;Whitman, SA;White, E;Zhang, DD;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

The Nrf2-Keap1 signaling pathway is a protective mechanism promoting cell survival. Activation of th....

An Adult Mouse Model of Vibrio cholerae-induced Diarrhea for Studying Pathogenesis and Potential Therapy of Cholera

PLoS Neglected Tropical Diseases

Sawasvirojwong, S;Srimanote, P;Chatsudthipong, V;Muanprasat, C;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

Cholera is a diarrheal disease causing significant morbidity and mortality worldwide. This study aim....

Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis

Nature Chemical Biology

Hett, EC;Slater, LH;Mark, KG;Kawate, T;Monks, BG;Stutz, A;Latz, E;Hung, DT;

Product: Anthrax Edema Factor (EF), Recombinant from B. anthracis

Formation of the inflammasome, a scaffolding complex that activates caspase-1, is important in numer....

Targeted delivery of TrkB receptor to phrenic motoneurons enhances functional recovery of rhythmic phrenic activity after cervical spinal hemisection

PLoS ONE

Gransee, HM;Zhan, WZ;Sieck, GC;Mantilla, CB;

Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

Progressive recovery of rhythmic phrenic activity occurs over time after a spinal cord hemisection i....

Pharmacological dissection of the actions of the Mu opioid receptor in the Rostroventral medial medulla

Thesis

Cano, M;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

IL-7/anti-IL-7 mAb complexes augment cytokine potency in mice through association with IgG-Fc and by competition with IL-7R

Blood

Martin, CE;van Leeuwen, EM;Im, SJ;Roopenian, DC;Sung, YC;Surh, CD;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Interleukin-7 (IL-7) is essential to T-cell survival as well as homeostatic proliferation, and clini....

Autoimmune memory T helper 17 cell function and expansion are dependent on interleukin-23

Cell Reports

Haines, CJ;Chen, Y;Blumenschein, WM;Jain, R;Chang, C;Joyce-Shaikh, B;Porth, K;Boniface, K;Mattson, J;Basham, B;Anderton, SM;McClanahan, TK;Sadekova, S;Cua, DJ;McGeachy, MJ;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Interleukin-23 (IL-23) is essential for the differentiation of pathogenic effector T helper 17 (Th17....

Signaling of high mobility group box 1 (HMGB1) through toll-like receptor 4 in macrophages requires CD14

Molecular Medicine

Kim, S;Kim, SY;Pribis, JP;Lotze, M;Mollen, KP;Shapiro, R;Loughran, P;Scott, MJ;Billiar, TR;

Product: ULTRA PURE LPS from Escherichia coli O111:B4

High mobility group box 1 (HMGB1) is a DNA-binding protein that possesses cytokinelike, proinflammat....

Localization of gadolinium-loaded CPMV to sites of inflammation during central nervous system autoimmunity

Journal Of Materials Chemistry B

Shriver, LP;Plummer, EM;Thomas, DM;Ho, S;Manchester, M;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Contrast-enhanced magnetic resonance imaging (MRI) allows rapid non-invasive diagnosis of central ne....

C-type lectin MCL is an FcR-coupled receptor that mediates the adjuvanticity of mycobacterial cord factor

Immunity

Miyake, Y;Toyonaga, K;Mori, D;Kakuta, S;Hoshino, Y;Oyamada, A;Yamada, H;Ono, K;Suyama, M;Iwakura, Y;Yoshikai, Y;Yamasaki, S;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Cord factor, also called trehalose-6,6′-dimycolate (TDM), is a potent mycobacterial adjuvant. ....

Hematopoietic sphingosine 1-phosphate lyase deficiency decreases atherosclerotic lesion development in LDL-receptor deficient mice

PLoS ONE

Bot, M;Van Veldhoven, PP;de Jager, SC;Johnson, J;Nijstad, N;Van Santbrink, PJ;Westra, MM;Van Der Hoeven, G;Gijbels, MJ;Mller-Tidow, C;Varga, G;Tietge, UJ;Kuiper, J;Van Berkel, TJ;Nofer, JR;Bot, I;Biessen, EA;

Product: LPS from Salmonella minnesota R595 (Re)

Altered sphingosine 1-phosphate (S1P) homeostasis and signaling is implicated in various inflammator....

Enhanced production of full-length immunoglobulin G via the signal recognition particle (SRP)-dependent pathway in Escherichia coli

Journal Of Biotechnology

Lee, YJ;Kim, HS;Ryu, AJ;Jeong, KJ;

Product: Anthrax Protective Antigen, Activated (PA 63) from B. anthracis

Because of the lack of post-translational glycosylation, Escherichia coli is not a preferable host f....

Retrograde tracing technique for neonatal animals.

Methods In Molecular Biology

Funakoshi, K;Yoshikawa, A;Atobe, Y;

Product: Anti-Cholera Toxin B Subunit (Goat)

Tract tracing is a fundamental technique in neuroanatomy for examining fiber connections in the nerv....

Common interactions between S100A4 and S100A9 defined by a novel chemical probe

PLoS ONE

Bjrk, P;Kllberg, E;Wellmar, U;Riva, M;Olsson, A;He, Z;Trngren, M;Liberg, D;Ivars, F;Leanderson, T;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

S100A4 and S100A9 proteins have been described as playing roles in the control of tumor growth and m....

Mycoplasma pneumoniae CARDS toxin is internalized via clathrin-mediated endocytosis

PLoS ONE

Krishnan, M;Kannan, TR;Baseman, JB;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

Bacterial toxins possess specific mechanisms of binding and uptake by mammalian cells. Mycoplasma pn....

Development and preclinical evaluation of safety and immunogenicity of an oral ETEC vaccine containing inactivated E. coli bacteria overexpressing colonization factors CFA/I, CS3, CS5 and CS6 combined with a hybrid LT/CT B subunit antigen, administered al

Vaccine

Holmgren, J;Bourgeois, L;Carlin, N;Clements, J;Gustafsson, B;Lundgren, A;Nygren, E;Tobias, J;Walker, R;Svennerholm, AM;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

A first-generation oral inactivated whole-cell enterotoxigenic Escherichia coli (ETEC) vaccine, comp....

Method of inhibiting AB-type bacterial toxins and treatment for associated diseases

Thesis

Taylor, M;Teter, K;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

Disclosed herein are compounds useful in inhibiting the action of AB-type bacterial toxins such as c....

PD-1 Interaction with PD-L1 but not PD-L2 on B-cells Mediates Protective Effects of Estrogen against EAE

Journal Of Clinical Cell Immunology

Bodhankar, S;Galipeau, D;Vandenbark, AA;Offner, H;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Increased remissions in multiple sclerosis (MS) during late pregnancy may result from high levels of....

Regulator of G-protein signaling – 5 (RGS5) is a novel repressor of hedgehog signaling.

PLoS ONE

Mahoney, WM;Gunaje, J;Daum, G;Dong, XR;Majesky, MW;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Hedgehog (Hh) signaling plays fundamental roles in morphogenesis, tissue repair, and human disease. ....

CNS effects of blood-borne relaxin on the paraventricular nucleus of the hypothalamus

Thesis

Brown, R;

Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

Pregnancy is characterized by increased blood volume and baseline sympathetic nerve activity, and pr....

CD11c+ alveolar macrophages are a source of IL-23 during lipopolysaccharide-induced acute lung injury

Shock

Bosmann, M;Grailer, JJ;Russkamp, NF;Ruemmler, R;Zetoune, FS;Sarma, JV;Ward, PA;

Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae

Acute lung injury (ALI) is a severe pulmonary disease causing high numbers of fatalities worldwide. ....

Mast cell activation and neutrophil recruitment promotes early and robust inflammation in the meninges in EAE

Journal of Autoimmunity

Christy, AL;Walker, ME;Hessner, MJ;Brown, MA;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

The meninges are often considered inert tissues that house the CSF and provide protection for the br....

Cutting edge: the pathogenicity of IFN–producing Th17 cells is independent of T-bet

The Journal of Immunology

Duhen, R;Glatigny, S;Arbelaez, CA;Blair, TC;Oukka, M;Bettelli, E;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

During the development of experimental autoimmune encephalomyelitis (EAE), the proportion of pathoge....

Amelioration of experimental autoimmune encephalomyelitis by the quinoline-3-carboxamide paquinimod: reduced priming of proinflammatory effector CD4(+) T cells

The American Journal Of Pathology

Helmersson, S;Sundstedt, A;Deronic, A;Leanderson, T;Ivars, F;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Quinoline-3-carboxamide compounds (Q compounds) have demonstrated efficacy in treating autoimmune di....

Partial MHC class II constructs inhibit MIF/CD74 binding and downstream effects

European Journal Of Immunology

Benedek, G;Meza-Romero, R;Andrew, S;Leng, L;Burrows, GG;Bourdette, D;Offner, H;Bucala, R;Vandenbark, AA;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

MIF and its receptor, CD74, are pivotal regulators of the immune system. Here, we demonstrate for th....

Lentiviral-mediated administration of IL-25 in the CNS induces alternative activation of microglia

Gene Therapy

Maiorino, C;Khorooshi, R;Ruffini, F;Lbner, M;Bergami, A;Garzetti, L;Martino, G;Owens, T;Furlan, R;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Interleukin-25 (IL-25) is the only anti-inflammatory cytokine of the IL-17 family, and it has been s....

Identification of Immunomodulatory Cells Induced By 670 nm Light Therapy in an Animal Model of Multiple Sclerosis

Thesis

Koester, EC;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Innate immune signaling induces expression and shedding of the heparan sulfate proteoglycan syndecan-4 in cardiac fibroblasts and myocytes, affecting inflammation in the pressure-overloaded heart

The FEBS Journal

Strand, ME;Herum, KM;Rana, ZA;Skrbic, B;Askevold, ET;Dahl, CP;Vistnes, M;Hasic, A;Kvaly, H;Sjaastad, I;Carlson, CR;Tnnessen, T;Gullestad, L;Christensen, G;Lunde, IG;

Product: LPS from Escherichia coli O111:B4

Sustained pressure overload induces heart failure, the main cause of mortality in the Western world.....

Lumican is increased in experimental and clinical heart failure, and its production by cardiac fibroblasts is induced by mechanical and proinflammatory stimuli

The FEBS Journal

Engebretsen, KV;Lunde, IG;Strand, ME;Waehre, A;Sjaastad, I;Marstein, HS;Skrbic, B;Dahl, CP;Askevold, ET;Christensen, G;Bjrnstad, JL;Tnnessen, T;

Product: LPS from Escherichia coli O111:B4

During progression to heart failure (HF), myocardial extracellular matrix (ECM) alterations and tiss....

Zymosan activates protein kinase A via adenylyl cyclase VII to modulate innate immune responses during inflammation

Molecular Immunology

Jiang, LI;Sternweis, PC;Wang, JE;

Product: LPS from Salmonella minnesota R595 (Re)

Pathogens use a variety of strategies to evade host immune defenses. A powerful way to suppress immu....

Expression of the Nrf2-system at the blood-CSF barrier is modulated by neonatal inflammation and hypoxia-ischemia

Journal Of Inherited Metabolic Disease

D'Angelo, B;Ek, CJ;Sandberg, M;Mallard, C;

Product: ULTRA PURE LPS from Escherichia coli O55:B5

Transcription factor NF-E2-related factor-2 (Nrf2) is a key regulator of endogenous anti-oxidant sys....

Cortical projections to the superior colliculus in tree shrews (Tupaia belangeri)

The Journal of Comparative Neurology

Baldwin, MK;Wei, H;Reed, JL;Bickford, ME;Petry, HM;Kaas, JH;

Product: Anti-Cholera Toxin B Subunit (Goat)

The visuomotor functions of the superior colliculus depend not only on direct inputs from the retina....

Projections of the superior colliculus to the pulvinar in prosimian galagos (Otolemur garnettii) and VGLUT2 staining of the visual pulvinar

The Journal of Comparative Neurology

Baldwin, MK;Balaram, P;Kaas, JH;

Product: Anti-Cholera Toxin B Subunit (Goat)

An understanding of the organization of the pulvinar complex in prosimian primates has been somewhat....

Nanogel-based PspA intranasal vaccine prevents invasive disease and nasal colonization by Streptococcus pneumoniae

Infection And Immunity

Kong, IG;Sato, A;Yuki, Y;Nochi, T;Takahashi, H;Sawada, S;Mejima, M;Kurokawa, S;Okada, K;Sato, S;Briles, DE;Kunisawa, J;Inoue, Y;Yamamoto, M;Akiyoshi, K;Kiyono, H;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

To establish a safer and more effective vaccine against pneumococcal respiratory infections, current....

Characterization of in vitro Chlamydia muridarum persistence and utilization in an in vivo mouse model of Chlamydia vaccine

American Journal Of Reproductive Immunology

Carey, AJ;Huston, WM;Cunningham, KA;Hafner, LM;Timms, P;Beagley, KW;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

Chlamydia trachomatis genital tract infections are easily treated with antibiotics; however, the maj....

Secretory expression and efficient purification of recombinant anthrax toxin lethal factor with full biological activity in E. coli

Protein Expression And Purification

Liu, J;Cai, C;Guo, Q;Zhang, J;Dong, D;Li, G;Fu, L;Xu, J;Chen, W;

Product: Anthrax Lethal Factor (LF), Recombinant from B. anthracis

Lethal factor (LF), a virulence factor of Bacillus anthracis, plays key roles in anthrax pathogenesi....

Noradrenaline is a stress-associated metaplastic signal at GABA synapses

Nature Neuroscience

Inoue, W;Baimoukhametova, DV;Fzesi, T;Wamsteeker Cusulin, JI;Koblinger, K;Whelan, PJ;Pittman, QJ;Bains, JS;

Product: Botulinum Neurotoxin Type C Light Chain, Recombinant

Exposure to a stressor sensitizes behavioral and hormonal responses to future stressors. Stress-asso....

Glucocorticoid feedback uncovers retrograde opioid signaling at hypothalamic synapses.

Nature Neuroscience

Wamsteeker Cusulin, JI;Fzesi, T;Inoue, W;Bains, JS;

Product: Botulinum Neurotoxin Type C Light Chain, Recombinant

Stressful experience initiates a neuroendocrine response culminating in the release of glucocorticoi....

G-mediated activation of protein kinase D exhibits subunit specificity and requires G-responsive phospholipase C isoforms

Cell Communication And Signaling

Lau, WW;Chan, AS;Poon, LS;Zhu, J;Wong, YH;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Protein kinase D (PKD) constitutes a novel family of serine/threonine protein kinases implicated in ....

Supplemental Information Dendritic Peptide Release Mediates Interpopulation Crosstalk between Neurosecretory and Preautonomic Networks

Neuron

Son, SJ;Filosa, JA;Potapenko, ES;Biancardi, VC;

Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

Although communication between neurons is considered a function of the synapse, neurons also release....

Secondary B cell receptor diversification is necessary for T cell mediated neuro-inflammation during experimental autoimmune encephalomyelitis.

PLoS ONE

Galicia, G;Boulianne, B;Pikor, N;Martin, A;Gommerman, JL;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Clinical studies of B cell depletion in Multiple Sclerosis (MS) have revealed that B Lymphocytes are....

Pituitary adenylate cyclase activating peptide deficient mice exhibit impaired thymic and extrathymic regulatory T cell proliferation during EAE

PLoS ONE

Tan, YV;Abad, C;Wang, Y;Lopez, R;Waschek, JA;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

We have shown that mice deficient in pituitary adenylate cyclase-activating polypeptide (PACAP, gene....

Microbe-dependent CD11b+ IgA+ plasma cells mediate robust early-phase intestinal IgA responses in mice

Nature Communications

Kunisawa, J;Gohda, M;Hashimoto, E;Ishikawa, I;Higuchi, M;Suzuki, Y;Goto, Y;Panea, C;Ivanov, II;Sumiya, R;Aayam, L;Wake, T;Tajiri, S;Kurashima, Y;Shikata, S;Akira, S;Takeda, K;Kiyono, H;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

Intestinal plasma cells predominantly produce immunoglobulin (Ig) A, however, their functional diver....

Immunization with a MOMP-based vaccine protects mice against a pulmonary Chlamydia challenge and identifies a disconnection between infection and pathology

PLoS ONE

O'Meara, CP;Armitage, CW;Harvie, MC;Timms, P;Lycke, NY;Beagley, KW;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

Chlamydia pneumoniae is responsible for up to 20% of community acquired pneumonia and can exacerbate....

Potential of urinary metabolites for diagnosing multiple sclerosis.

ACS Chemical Biology

Gebregiworgis, T;Massilamany, C;Gangaplara, A;Thulasingam, S;Kolli, V;Werth, MT;Dodds, ED;Steffen, D;Reddy, J;Powers, R;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

A definitive diagnostic test for multiple sclerosis (MS) does not exist; instead physicians use a co....

Identification of novel host-targeted compounds that protect from anthrax lethal toxin-induced cell death

ACS Chemical Biology

Slater, LH;Hett, EC;Mark, K;Chumbler, NM;Patel, D;Lacy, DB;Collier, RJ;Hung, DT;

Product: Anthrax Edema Factor (EF), Recombinant from B. anthracis

Studying how pathogens subvert the host to cause disease has contributed to the understanding of fun....

Electroacupuncture improves thermal and mechanical sensitivities in a rat model of postherpetic neuralgia

Molecular Pain

Wu, CH;Lv, ZT;Zhao, Y;Gao, Y;Li, JQ;Gao, F;Meng, XF;Tian, B;Shi, J;Pan, HL;Li, M;

Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

Electroacupuncture (EA) is effective in relieving pain in patients with postherpetic neuralgia (PHN)....

Fibrin facilitates both innate and T cell-mediated defense against Yersinia pestis.

The Journal of Immunology

Luo, D;Lin, JS;Parent, MA;Mullarky-Kanevsky, I;Szaba, FM;Kummer, LW;Duso, DK;Tighe, M;Hill, J;Gruber, A;Mackman, N;Gailani, D;Smiley, ST;

Product: Cholera Toxin (AZIDE-FREE) from Vibrio cholerae

The Gram-negative bacterium Yersinia pestis causes plague, a rapidly progressing and often fatal dis....

Recurrent exposure to subclinical lipopolysaccharide increases mortality and induces cardiac fibrosis in mice

PLoS ONE

Lew, WY;Bayna, E;Molle, ED;Dalton, ND;Lai, NC;Bhargava, V;Mendiola, V;Clopton, P;Tang, T;

Product: LPS from Escherichia coli O55:B5

Circulating subclinical lipopolysaccharide (LPS) occurs in health and disease. Ingesting high fatty ....

Central neuropathic pain in MS is due to distinct thoracic spinal cord lesions

The University Of Arizona

Okuda, DT;Melmed, K;Matsuwaki, T;Blomqvist, A;Craig, AD;

Product: Cholera Toxin B Subunit (Choleragenoid) from Vibrio cholerae in Low Salt

To determine a neuro-anatomic cause for central neuropathic pain (CNP) observed in multiple sclerosi....

Sex bias in experimental immune-mediated, drug-induced liver injury in BALB/c mice: suggested roles for Tregs, estrogen, and IL-6

PLoS ONE

Cho, J;Kim, L;Li, Z;Rose, NR;Talor, MV;Njoku, DB;

Product: Pertussis Toxin from B. pertussis, Lyophilized in Buffer

Immune-mediated, drug-induced liver injury (DILI) triggered by drug haptens is more prevalent in wom....

Peptidergic CGRP primary sensory neurons encode heat and itch and tonically suppress sensitivity to cold

Neuron

McCoy, ES;Taylor-Blake, B;Street, SE;Pribisko, AL;Zheng, J;Zylka, MJ;

Product: Diphtheria Toxin, Unnicked, from Corynebacterium diphtheriae

Calcitonin gene-related peptide (CGRP) is a classic molecular marker of peptidergic primary somatose....

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Bacterial Toxin Terminology

July 23, 2018

By: douano@listlabs.com

By: Mary N. Wessling, Ph.D. ELS In this blog we will unravel the terminology describing bacterial toxins. In general, there are at least three ways that bacterial toxins are described in the literature: by their biological designation—the genus and/or species from which they come by the origin of the toxin, either as innate to the […]

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